JP4704032B2 - プロテインキナーゼ阻害剤 - Google Patents

プロテインキナーゼ阻害剤 Download PDF

Info

Publication number: JP4704032B2
Authority: JP; Japan
Prior art keywords: alkyl; aryl; hetaryl; compound; carcinoma
Prior art date: 2002-05-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

JP2004507453A

Other languages

English (en)

Japanese (ja)

Other versions

JP2005535596A (ja

Inventor

クリストファー・ジョン・バーンズ

シャンヨン・ブ

アンドリュー・フレデリック・ウィルクス

Original Assignee

ワイエム・バイオサイエンシズ・オーストラリア・ピーティーワイ・リミテッド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-23

Filing date

2003-05-23

Publication date

2011-06-15

2003-05-23 Application filed by ワイエム・バイオサイエンシズ・オーストラリア・ピーティーワイ・リミテッド filed Critical ワイエム・バイオサイエンシズ・オーストラリア・ピーティーワイ・リミテッド

2003-05-23 Priority claimed from PCT/AU2003/000629 external-priority patent/WO2003099796A1/en

2005-11-24 Publication of JP2005535596A publication Critical patent/JP2005535596A/ja

2011-06-15 Application granted granted Critical

2011-06-15 Publication of JP4704032B2 publication Critical patent/JP4704032B2/ja

2023-05-23 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

WOGGCCCSBXWIMX-WJONVMNZSA-N C/C(/NCc1ccc[o]1)=C\N=C/CCl Chemical compound C/C(/NCc1ccc[o]1)=C\N=C/CCl WOGGCCCSBXWIMX-WJONVMNZSA-N 0.000 description 1
REDNYMGXSZQBOU-UXBLZVDNSA-N C/C(/c1cc(Cl)ccc1)=N\O Chemical compound C/C(/c1cc(Cl)ccc1)=N\O REDNYMGXSZQBOU-UXBLZVDNSA-N 0.000 description 1
RCNYSRKPADRFJI-UHFFFAOYSA-N COc1cc(-c2nc(NCc3ccc[o]3)cnc2)ccc1O Chemical compound COc1cc(-c2nc(NCc3ccc[o]3)cnc2)ccc1O RCNYSRKPADRFJI-UHFFFAOYSA-N 0.000 description 1
FBKJNNPCCRROIA-HNNXBMFYSA-N C[C@@H](c1ccccc1)Nc1nc(-c(cc2)ccc2NC(C2CC2)=O)cnc1 Chemical compound C[C@@H](c1ccccc1)Nc1nc(-c(cc2)ccc2NC(C2CC2)=O)cnc1 FBKJNNPCCRROIA-HNNXBMFYSA-N 0.000 description 1

Images

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

JP2004507453A 2002-05-23 2003-05-23 プロテインキナーゼ阻害剤 Expired - Fee Related JP4704032B2 (ja)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
AUPS2515		2002-05-23
AUPS2515A AUPS251502A0 (en)	2002-05-23	2002-05-23	Protein kinase inhibitors
US39907002P	2002-07-26	2002-07-26
US60/399,070		2002-07-26
PCT/AU2003/000629 WO2003099796A1 (en)	2002-05-23	2003-05-23	Protein kinase inhibitors

Publications (2)

Publication Number	Publication Date
JP2005535596A JP2005535596A (ja)	2005-11-24
JP4704032B2 true JP4704032B2 (ja)	2011-06-15

Family

ID=3836079

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2004507453A Expired - Fee Related JP4704032B2 (ja)	2002-05-23	2003-05-23	プロテインキナーゼ阻害剤

Country Status (4)

Country	Link
JP (1)	JP4704032B2 (ko)
KR (1)	KR101027426B1 (ko)
AU (1)	AUPS251502A0 (ko)
ZA (1)	ZA200409341B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002953255A0 (en) *	2002-12-11	2003-01-02	Cytopia Research Pty Ltd	Protein kinase inhibitors
PT1689715E (pt)	2003-12-03	2011-05-16	Ym Biosciences Australia Pty	Inibidores da tubulina
EP2099774A4 (en) *	2006-11-15	2010-11-24	Ym Biosciences Australia Pty L	INHIBITORS OF KINASEACTIVITY
US8436171B2 (en) *	2008-02-01	2013-05-07	Akinion Pharmaceuticals Ab	Amino substituted pyrazines as inhibitors or protein kinases
WO2013004332A1 (en) *	2011-07-07	2013-01-10	Merck Patent Gmbh	Substituted azaheterocycles for the treatment of cancer
AU2014205481A1 (en) *	2013-01-10	2015-08-27	Gilead Sciences, Inc.	Therapeutic indications of kinase inhibitors
DK3007689T3 (en) *	2013-01-10	2018-06-14	Pulmokine Inc	NON-SELECTIVE KINASE INHIBITORS
ES2959419T3 (es) *	2013-10-11	2024-02-26	Pulmokine Inc	Formulaciones secas por aspersión
WO2018081567A1 (en)	2016-10-27	2018-05-03	Pulmokine, Inc.	Combination therapy for treating pulmonary hypertension

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2004523474A (ja) *	2000-09-20	2004-08-05	オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド	チロシンキナーゼモジュレーターとしてのピラジン誘導体

2002
- 2002-05-23 AU AUPS2515A patent/AUPS251502A0/en not_active Abandoned
2003
- 2003-05-23 KR KR1020047018881A patent/KR101027426B1/ko active IP Right Grant
- 2003-05-23 JP JP2004507453A patent/JP4704032B2/ja not_active Expired - Fee Related
2004
- 2004-11-19 ZA ZA200409341A patent/ZA200409341B/en unknown

Also Published As

Publication number	Publication date
AUPS251502A0 (en)	2002-06-13
KR20050010010A (ko)	2005-01-26
JP2005535596A (ja)	2005-11-24
KR101027426B1 (ko)	2011-04-11
ZA200409341B (en)	2006-02-22

Legal Events

Date	Code	Title	Description
2005-12-22	A621	Written request for application examination	Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20051221
2009-07-15	A131	Notification of reasons for refusal	Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090714
2009-09-12	A521	Request for written amendment filed	Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090911
2010-09-29	A131	Notification of reasons for refusal	Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100928
2010-12-10	A521	Request for written amendment filed	Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20101209
2011-01-31	TRDD	Decision of grant or rejection written
2011-02-09	A01	Written decision to grant a patent or to grant a registration (utility model)	Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20110208
2011-03-17	A61	First payment of annual fees (during grant procedure)	Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20110309
2011-03-18	R150	Certificate of patent or registration of utility model	Ref document number: 4704032 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150
2014-03-11	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2015-03-17	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2016-03-15	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2017-03-14	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2018-03-20	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2019-03-12	R250	Receipt of annual fees	Free format text: JAPANESE INTERMEDIATE CODE: R250
2020-03-18	LAPS	Cancellation because of no payment of annual fees

Publication	Publication Date	Title
EP1513821B1 (en)	2007-10-31	Protein kinase inhibitors
JP5283336B2 (ja)	2013-09-04	選択的キナーゼ阻害剤
EP1511742B1 (en)	2010-02-03	Kinase inhibitors
KR101211514B1 (ko)	2012-12-12	아졸계 키나제 저해제
JP4704032B2 (ja)	2011-06-15	プロテインキナーゼ阻害剤
JP4772325B2 (ja)	2011-09-14	キナーゼ阻害剤
AU2003232919B2 (en)	2009-03-05	Protein kinase inhibitors
KR101169964B1 (ko)	2012-08-06	키나아제 저해제
MXPA06005983A (en)	2006-12-13	Azole-based kinase inhibitors