JP4436658B2 - ボリューム灌流を計算するための方法及び装置 - Google Patents
ボリューム灌流を計算するための方法及び装置 Download PDFInfo
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- JP4436658B2 JP4436658B2 JP2003393333A JP2003393333A JP4436658B2 JP 4436658 B2 JP4436658 B2 JP 4436658B2 JP 2003393333 A JP2003393333 A JP 2003393333A JP 2003393333 A JP2003393333 A JP 2003393333A JP 4436658 B2 JP4436658 B2 JP 4436658B2
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- 230000010412 perfusion Effects 0.000 title claims description 23
- 238000000034 method Methods 0.000 title description 27
- 210000000056 organ Anatomy 0.000 claims description 43
- 238000003384 imaging method Methods 0.000 claims description 40
- 238000002591 computed tomography Methods 0.000 claims description 36
- 238000013170 computed tomography imaging Methods 0.000 claims description 20
- 239000002872 contrast media Substances 0.000 claims description 13
- 230000005855 radiation Effects 0.000 claims description 8
- 238000001914 filtration Methods 0.000 claims description 6
- 210000004556 brain Anatomy 0.000 claims description 5
- 230000002123 temporal effect Effects 0.000 claims description 4
- 238000005259 measurement Methods 0.000 description 8
- 238000012545 processing Methods 0.000 description 7
- 238000004364 calculation method Methods 0.000 description 5
- 238000005070 sampling Methods 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000002238 attenuated effect Effects 0.000 description 2
- 238000003672 processing method Methods 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/507—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for determination of haemodynamic parameters, e.g. perfusion CT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/032—Transmission computed tomography [CT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/48—Diagnostic techniques
- A61B6/488—Diagnostic techniques involving pre-scan acquisition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
- A61B6/5211—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data
- A61B6/5217—Devices using data or image processing specially adapted for radiation diagnosis involving processing of medical diagnostic data extracting a diagnostic or physiological parameter from medical diagnostic data
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S378/00—X-ray or gamma ray systems or devices
- Y10S378/901—Computer tomography program or processor
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- High Energy & Nuclear Physics (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Theoretical Computer Science (AREA)
- Physiology (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Primary Health Care (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Description
12 ガントリ
14 X線源
18 検出器アレイ
20 検出器素子
22 患者
46 モータ式テーブル
48 ガントリ開口
Claims (6)
- 空間的に静止した臓器内のボリューム灌流を計算するためのコンピュータ断層撮影(CT)イメージングシステム(10)であって、
放射線源(14)と、
面検出器(18)と、
前記放射線源及び前記面検出器に動作可能に連結されたコンピュータ(36)と、
を含み、前記コンピュータが、
前記面検出器が全てのビュー角度において該イメージングシステムの撮像領域内に前記空間的に静止した臓器を含むように、該面検出器を位置決めし(62)、
該CTイメージングシステムをシネモードで動作させて、前記空間的に静止した臓器内の生体組織ダイナミックスを表す複数の投影データを収集し(64)、
前記投影データを用いて前記生体組織の造影剤ダイナミックスの再構成を生成し(66)、
前記生体組織ダイナミックスを表す前記投影データを用いて前記臓器内のボリューム灌流を計算する(68)、ように構成されており、
前記コンピュータ(36)が、前記複数の投影データを特定の時点に補間(88)することにより、改善された時間分解能で再構成を生成することを可能にするように更に構成されていることを特徴とする、
ことを特徴とするCTイメージングシステム(10)。 - 前記面検出器が該イメージングシステムの撮像領域内に前記空間的に静止した臓器を含むように該面検出器(18)を位置決めするために、前記コンピュータが、前記面検出器が脳の撮像領域を含むように該面検出器を位置決めするように更に構成されていることを特徴とする、請求項1に記載のCTイメージングシステム(10)。
- 該CTイメージングシステムをシネモードで動作させて、前記空間的に静止した臓器内の前記生体組織ダイナミックスを表す複数の投影データを収集することが、該CTイメージングシステムを動作させることを含み、前記コンピュータ(36)が、該CTシステムをシネモードで動作させて、各撮像位置での前記空間的に静止した臓器内の造影剤の取込み及び洗出しを測定する投影データを適切な頻度でサンプリングするように、前記空間的に静止した臓器内の前記生体組織ダイナミックスを表す複数の投影データを収集するように更に構成されていることを特徴とする、請求項1に記載のCTイメージングシステム(10)。
- 前記コンピュータ(36)が、前記面検出器(18)の多数列を多重化するように更に構成されることを特徴とする、請求項1に記載のCTイメージングシステム(10)。
- 前記コンピュータ(36)が、各ビュー角度での前記投影データをフィルタ処理(86)することにより、改善された画質で再構成を生成することを可能にするように更に構成されていることを特徴とする、請求項1に記載のCTイメージングシステム(10)。
- 各ビュー角度での前記投影データをフィルタ処理(86)することにより、前記患者(22)へ適用する放射線量を減少させることを可能にすることを特徴とする、請求項5に記載のCTイメージングシステム(10)。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/304,380 US6888914B2 (en) | 2002-11-26 | 2002-11-26 | Methods and apparatus for computing volumetric perfusion |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2004174249A JP2004174249A (ja) | 2004-06-24 |
JP2004174249A5 JP2004174249A5 (ja) | 2007-01-11 |
JP4436658B2 true JP4436658B2 (ja) | 2010-03-24 |
Family
ID=32298032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2003393333A Expired - Fee Related JP4436658B2 (ja) | 2002-11-26 | 2003-11-25 | ボリューム灌流を計算するための方法及び装置 |
Country Status (5)
Country | Link |
---|---|
US (3) | US6888914B2 (ja) |
JP (1) | JP4436658B2 (ja) |
CN (1) | CN1276743C (ja) |
DE (1) | DE10354737A1 (ja) |
NL (1) | NL1024854C2 (ja) |
Families Citing this family (38)
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US6888914B2 (en) * | 2002-11-26 | 2005-05-03 | General Electric Company | Methods and apparatus for computing volumetric perfusion |
US20040116795A1 (en) * | 2002-12-17 | 2004-06-17 | Collins William F. | Determination of dose-enhancing agent concentration and dose enhancement ratio |
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DE10335663A1 (de) * | 2003-08-04 | 2005-03-10 | Siemens Ag | Verfahren zur automatischen Kalibrierung von Perfusionsparameterbildern |
US6934353B2 (en) * | 2003-10-01 | 2005-08-23 | Ge Medical Systems Global Technology Company, Llc | Methods, apparatus, and computer readable mediums for performing perfusion studies |
US7918875B2 (en) * | 2004-10-25 | 2011-04-05 | Lanx, Inc. | Interspinous distraction devices and associated methods of insertion |
US7062006B1 (en) * | 2005-01-19 | 2006-06-13 | The Board Of Trustees Of The Leland Stanford Junior University | Computed tomography with increased field of view |
EP1846753B1 (en) * | 2005-02-04 | 2012-11-07 | Koninklijke Philips Electronics N.V. | System for the determination of vessel geometry and flow characteristics |
JP4170305B2 (ja) * | 2005-04-05 | 2008-10-22 | ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー | 放射線撮影装置 |
JP4713920B2 (ja) * | 2005-04-15 | 2011-06-29 | 株式会社東芝 | X線コンピュータ断層撮影装置 |
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DE102007024451B4 (de) * | 2007-05-25 | 2010-07-08 | Siemens Ag | Ermittlungsverfahren für örtlich dreidimensional aufgelöste Anwesenheitsverteilungen einer Substanz in einem Gefäßsystem und hiermit korrespondierende Einrichtungen |
WO2008146056A1 (en) * | 2007-05-30 | 2008-12-04 | Ruder Boskovic Institute | A method for determining importance of fractions of biological mixtures separated by a chromatographic method for discrimination of cell or tissue physiological conditions |
US7983460B2 (en) * | 2007-06-08 | 2011-07-19 | General Electric Company | Method and system for performing high temporal resolution bolus detection using CT image projection data |
DE102007037996A1 (de) * | 2007-08-10 | 2009-02-19 | Siemens Ag | Verfahren zur dreidimensionalen Darstellung einer bewegten Struktur durch ein tomographisches Verfahren |
WO2009040742A2 (en) * | 2007-09-27 | 2009-04-02 | Philips Intellectual Property & Standards Gmbh | Methods for imaging the blood perfusion |
DE102008020814A1 (de) * | 2008-04-01 | 2009-10-15 | Siemens Aktiengesellschaft | Verfahren zur Ermittlung und Darstellung von Perfusionsparametern in der Tomographie |
US8200466B2 (en) | 2008-07-21 | 2012-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Method for tuning patient-specific cardiovascular simulations |
WO2010038161A2 (en) * | 2008-09-30 | 2010-04-08 | Koninklijke Philips Electronics, N.V. | Perfusion imaging |
DE102009004580A1 (de) * | 2009-01-14 | 2010-07-15 | Siemens Aktiengesellschaft | Abtast- und Rekonstruktionsverfahren eines CT-Systems und CT-System |
US7933377B2 (en) * | 2009-06-03 | 2011-04-26 | General Electric Company | Method of CT perfusion imaging and apparatus for implementing same |
EP2454925B1 (en) * | 2009-07-15 | 2022-10-05 | Mayo Foundation For Medical Education And Research | System and method for automatic tube potential selection for radiation dose reduction in ct |
US8654119B2 (en) | 2009-08-17 | 2014-02-18 | Mistretta Medical, Llc | System and method for four dimensional angiography and fluoroscopy |
US8643642B2 (en) | 2009-08-17 | 2014-02-04 | Mistretta Medical, Llc | System and method of time-resolved, three-dimensional angiography |
US8787521B2 (en) * | 2009-12-23 | 2014-07-22 | General Electric Company | System and method of iterative image reconstruction for computed tomography |
WO2011091300A2 (en) | 2010-01-24 | 2011-07-28 | Mistretta Medical, Llc | System and method for implementation of 4d time-energy subtraction computed tomography |
US8315812B2 (en) | 2010-08-12 | 2012-11-20 | Heartflow, Inc. | Method and system for patient-specific modeling of blood flow |
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-
2002
- 2002-11-26 US US10/304,380 patent/US6888914B2/en not_active Expired - Lifetime
-
2003
- 2003-11-21 DE DE10354737A patent/DE10354737A1/de not_active Ceased
- 2003-11-24 NL NL1024854A patent/NL1024854C2/nl not_active IP Right Cessation
- 2003-11-25 JP JP2003393333A patent/JP4436658B2/ja not_active Expired - Fee Related
- 2003-11-26 CN CNB2003101179557A patent/CN1276743C/zh not_active Expired - Fee Related
- 2003-11-26 US US10/724,461 patent/US7082180B2/en not_active Expired - Lifetime
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2005
- 2005-03-31 US US11/095,437 patent/US7054405B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NL1024854A1 (nl) | 2004-05-27 |
CN1509685A (zh) | 2004-07-07 |
US7082180B2 (en) | 2006-07-25 |
CN1276743C (zh) | 2006-09-27 |
DE10354737A1 (de) | 2004-06-03 |
US6888914B2 (en) | 2005-05-03 |
NL1024854C2 (nl) | 2005-07-05 |
US20040101085A1 (en) | 2004-05-27 |
US20050169420A1 (en) | 2005-08-04 |
US20040111023A1 (en) | 2004-06-10 |
US7054405B2 (en) | 2006-05-30 |
JP2004174249A (ja) | 2004-06-24 |
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