JP2020517269A - サンプルを調製するためのガラス化デバイス及び方法 - Google Patents
サンプルを調製するためのガラス化デバイス及び方法 Download PDFInfo
- Publication number
- JP2020517269A JP2020517269A JP2019557379A JP2019557379A JP2020517269A JP 2020517269 A JP2020517269 A JP 2020517269A JP 2019557379 A JP2019557379 A JP 2019557379A JP 2019557379 A JP2019557379 A JP 2019557379A JP 2020517269 A JP2020517269 A JP 2020517269A
- Authority
- JP
- Japan
- Prior art keywords
- sample
- sample chamber
- input
- cap
- fluid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims abstract description 32
- 238000004017 vitrification Methods 0.000 title claims description 108
- 239000002699 waste material Substances 0.000 claims abstract description 131
- 239000012530 fluid Substances 0.000 claims abstract description 96
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 66
- 239000007788 liquid Substances 0.000 claims abstract description 60
- 230000007246 mechanism Effects 0.000 claims abstract description 47
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 33
- 238000004891 communication Methods 0.000 claims abstract description 17
- 239000000463 material Substances 0.000 claims description 32
- 239000011148 porous material Substances 0.000 claims description 19
- 238000010257 thawing Methods 0.000 claims description 15
- -1 polypropylene Polymers 0.000 claims description 9
- 239000004743 Polypropylene Substances 0.000 claims description 5
- 229920001155 polypropylene Polymers 0.000 claims description 5
- 229920001634 Copolyester Polymers 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 4
- 230000008878 coupling Effects 0.000 claims description 4
- 238000010168 coupling process Methods 0.000 claims description 4
- 238000005859 coupling reaction Methods 0.000 claims description 4
- 239000004417 polycarbonate Substances 0.000 claims description 4
- 229920000515 polycarbonate Polymers 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 3
- 239000004020 conductor Substances 0.000 claims description 2
- 238000007710 freezing Methods 0.000 abstract description 11
- 230000008014 freezing Effects 0.000 abstract description 11
- 239000000523 sample Substances 0.000 description 249
- 238000001914 filtration Methods 0.000 description 34
- 239000000243 solution Substances 0.000 description 23
- 210000000287 oocyte Anatomy 0.000 description 14
- 210000002257 embryonic structure Anatomy 0.000 description 13
- 210000001161 mammalian embryo Anatomy 0.000 description 12
- 230000009471 action Effects 0.000 description 9
- 230000036961 partial effect Effects 0.000 description 9
- 239000010808 liquid waste Substances 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 230000000717 retained effect Effects 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 230000014759 maintenance of location Effects 0.000 description 5
- 239000004698 Polyethylene Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 229920000573 polyethylene Polymers 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000035899 viability Effects 0.000 description 4
- 239000011324 bead Substances 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 239000012780 transparent material Substances 0.000 description 3
- 239000002250 absorbent Substances 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000012472 biological sample Substances 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000005138 cryopreservation Methods 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000011067 equilibration Methods 0.000 description 2
- 230000035558 fertility Effects 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 210000004291 uterus Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000005587 bubbling Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000012628 flowing agent Substances 0.000 description 1
- 239000012520 frozen sample Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
- A01N1/0268—Carriers for immersion in cryogenic fluid, both for slow-freezing and vitrification, e.g. open or closed "straws" for embryos, oocytes or semen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0252—Temperature controlling refrigerating apparatus, i.e. devices used to actively control the temperature of a designated internal volume, e.g. refrigerators, freeze-drying apparatus or liquid nitrogen baths
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
- A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/22—Means for packing or storing viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/061—Sperm cells, spermatogonia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Reproductive Health (AREA)
- Thermal Sciences (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Sustainable Development (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Description
本出願は、2017年4月21日に提出された米国仮出願第62/488,655号への米国特許法第119条(e)の定めによる利益及び優先権を主張し、その全体が参照により本明細書に援用される。
本技術は、現在の技術の個別の態様の1つの例示として意図されているこの出願に記載された特定の実施形態に関して限定されない。その精神及び範囲から逸脱することなく本技術の多くの修正及び変形を行うことが可能であり、それは当業者には明らかであろう。本明細書で列挙されたものに加えて、本技術の範囲内で機能的に均等な方法及び装置も、当業者には先の記載から明らかであろう。このような修正及び変形が、本技術の範囲内に含まれることが意図される。本技術は、特定の方法、試薬、化合物組成又は当然に変化し得る生物系に限定されないことが理解されるべきである。また、本明細書で使用される用語は、単に特定の実施形態を記載すること目的としており、限定を意図していないことが理解されるべきである。
Claims (16)
- 入力ポートを有する入力部と、
サンプル室と、
前記サンプル室と流体連通する廃棄容器と、
前記サンプル室内にサンプルを保持しながら、前記入力ポートを通って導入される流体が前記サンプル室から前記廃棄容器内へと選択的に通過することを可能にするフィルタ機構と
を備え、
前記サンプル室、廃棄容器及びフィルタ機構は、前記サンプル室から前記フィルタ機構を通って前記廃棄容器へと毛細管現象によって流体を引き込むように構成される、ガラス化デバイス。 - 少なくとも1つの観察窓をさらに備え、前記観察窓は、前記サンプル室内のサンプルが前記観察窓を通して観察可能であるように構成される、請求項1に記載のガラス化デバイス。
- 前記入力ポートを閉じるために前記入力部に可逆的に結合することが可能なキャップをさらに備える、請求項1に記載のガラス化デバイス。
- 前記キャップは、前記キャップが前記入力部に結合されるときに前記ガラス化デバイス内の流体の流れを妨げるように前記入力ポートを密封するように構成される、請求項3に記載のガラス化デバイス。
- 前記フィルタ機構は、毛細管現象を促進するために複数のマイクロ流体チャネルを形成するようにサイズが決められかつ構成される複数の細孔を有するフィルタを備える、請求項1に記載のガラス化デバイス。
- 前記サンプル室は、液体窒素に耐性のある材料を備える、請求項1に記載のガラス化デバイス。
- 前記サンプル室は、熱伝導性材料を備える、請求項1に記載のガラス化デバイス。
- 前記サンプル室は、アクリル系材料、ポリプロピレン系材料、ポリカーボネート系材料、及びコポリエステル系材料の少なくとも1つから形成される、請求項1に記載のガラス化デバイス。
- 前記サンプル室は、0.002インチ以下の厚みの壁の有する、請求項1に記載のガラス化デバイス。
- サンプルを調製するための方法であって、
フィルタ機構に隣接するサンプル室内へサンプルを送達するステップと、
前記フィルタ機構が前記サンプル室内に前記サンプルを保持しながら、前記サンプル室を通して廃棄容器内へと流体力によって第1の流体を押し込むことによって前記第1の流体で前記サンプルを処理するステップと
を含み、
前記廃棄容器内へと前記第1の流体を押し込むことによって毛細管現象が開始され、後続の流体が前記サンプル室を通して前記廃棄容器内へと引き込まれる、方法。 - 前記フィルタ機構が前記サンプル室内に前記サンプルを保持しながら、前記サンプル室を通して前記廃棄容器内へと毛細管現象によって第2の流体を引き込むことによって前記第2の流体で前記サンプルを処理するステップをさらに含む、請求項10に記載の方法。
- 前記サンプル室における観察窓を通して前記サンプル室内の前記サンプルを観察するステップをさらに含む、請求項10に記載の方法。
- キャップを結合することにより前記サンプル室内に流体を流すための入力ポートを密封するステップをさらに含む、請求項10に記載の方法。
- 前記サンプル室内の前記サンプルをガラス化するステップをさらに含む、請求項10に記載の方法。
- 前記サンプルは、前記サンプル室を液体窒素と接触させることによりガラス化される、請求項14に記載の方法。
- 前記サンプル室を温溶液と接触させることにより前記サンプルを解凍するステップをさらに含む、請求項14に記載の方法。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2023094705A JP2023123549A (ja) | 2017-04-21 | 2023-06-08 | サンプルを調製するためのガラス化デバイス及び方法 |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762488655P | 2017-04-21 | 2017-04-21 | |
US62/488,655 | 2017-04-21 | ||
PCT/US2018/028672 WO2018195496A1 (en) | 2017-04-21 | 2018-04-20 | Vitrification device and method for preparing sample |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023094705A Division JP2023123549A (ja) | 2017-04-21 | 2023-06-08 | サンプルを調製するためのガラス化デバイス及び方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2020517269A true JP2020517269A (ja) | 2020-06-18 |
JP7295028B2 JP7295028B2 (ja) | 2023-06-20 |
Family
ID=62117079
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019557379A Active JP7295028B2 (ja) | 2017-04-21 | 2018-04-20 | サンプルを調製するためのガラス化デバイス及び方法 |
JP2023094705A Pending JP2023123549A (ja) | 2017-04-21 | 2023-06-08 | サンプルを調製するためのガラス化デバイス及び方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023094705A Pending JP2023123549A (ja) | 2017-04-21 | 2023-06-08 | サンプルを調製するためのガラス化デバイス及び方法 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20200093122A1 (ja) |
EP (2) | EP3612025B1 (ja) |
JP (2) | JP7295028B2 (ja) |
KR (2) | KR102615574B1 (ja) |
CN (2) | CN110769690B (ja) |
BR (1) | BR112019022066B1 (ja) |
WO (1) | WO2018195496A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022025092A1 (ja) * | 2020-07-28 | 2022-02-03 | 国立大学法人山梨大学 | 凍結卵培養装置及び凍結卵の培養方法 |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USD918707S1 (en) * | 2018-12-04 | 2021-05-11 | Jun Tao | Vitrification and storage device |
JP2021151209A (ja) * | 2020-03-25 | 2021-09-30 | 三菱製紙株式会社 | 凍結保存作業補助治具 |
USD951481S1 (en) * | 2020-09-01 | 2022-05-10 | TMRW Life Sciences, Inc. | Cryogenic vial |
USD963194S1 (en) | 2020-12-09 | 2022-09-06 | TMRW Life Sciences, Inc. | Cryogenic vial carrier |
WO2022125817A1 (en) | 2020-12-10 | 2022-06-16 | TMRW Life Sciences, Inc. | Specimen holder with wireless transponder for attachment to secimen collection body |
CN115777685A (zh) * | 2021-09-10 | 2023-03-14 | 深圳拜尔洛克生物技术有限公司 | 用于生物组织冷冻保存或解冻复苏的装置 |
CN113907065B (zh) * | 2021-11-08 | 2022-06-14 | 深圳先进技术研究院 | 换液处理芯片和冷冻载杆 |
CN114403126B (zh) * | 2021-12-06 | 2023-04-25 | 起源细胞技术(滁州)有限公司 | 一种封闭式胚胎冷冻管和使用方法 |
CN115885973A (zh) * | 2022-11-21 | 2023-04-04 | 香港中文大学深港创新研究院(福田) | 一种玻璃化冷冻工具及其使用方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002055673A1 (en) * | 2001-01-10 | 2002-07-18 | Biopore, Inc. | Cell concentrator and washer |
WO2013098825A1 (en) * | 2012-01-01 | 2013-07-04 | A.A. Cash Technology Ltd | Cryopreservation device for vitrification and method for using same |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5217693A (en) * | 1990-05-29 | 1993-06-08 | Mark Anderson | Embryo washing apparatus and process |
JP2005102619A (ja) * | 2003-09-30 | 2005-04-21 | Toshiba Corp | 細胞変態装置及び細胞変態方法 |
US20080038155A1 (en) * | 2004-12-21 | 2008-02-14 | Mcgill University | Tool and Method for Manipulating a Sample of Developmental Cells in a Process of Cryopreservation |
JP2005110695A (ja) * | 2005-01-06 | 2005-04-28 | Toyobo Co Ltd | 中空糸付き器具及びその使用方法 |
FR2891165B1 (fr) * | 2005-09-28 | 2008-01-11 | Cryo Bio System Sa | Ensemble de conditionnement d'un volume predetermine de substance a conserver par vitrification cryogenique. |
RU2349846C1 (ru) * | 2007-05-22 | 2009-03-20 | Институт биологического приборостроения Российской академии наук | Установка для витрификации ооцитов и эмбрионов млекопитающих |
US20090123992A1 (en) * | 2007-11-12 | 2009-05-14 | Milton Chin | Shape-Shifting Vitrification Device |
CN101200706B (zh) * | 2007-12-21 | 2010-09-29 | 安徽医科大学 | 生物样品玻璃化冷冻和保存工具 |
TR201820845T4 (tr) * | 2008-02-25 | 2019-01-21 | Genea Ip Holdings Pty Ltd | Biyolojik hücrelerin ve dokuların kriyoprezervasyonu. |
CN202873662U (zh) * | 2012-06-29 | 2013-04-17 | 冯贵雪 | 人类辅助生殖技术可多管同时冷冻的胚胎玻璃化冷冻装置 |
CN203369308U (zh) * | 2013-04-09 | 2014-01-01 | 上海安久生物科技有限公司 | 一种生物样本玻璃化冷冻载体及生物样本冻存组合装置 |
CN104412961A (zh) * | 2013-08-22 | 2015-03-18 | 薛松果 | 一种生物样品玻璃化冷冻和保存装置 |
US10099217B2 (en) * | 2013-12-12 | 2018-10-16 | 3M Innovative Properties Company | Apparatus and method for preparing a biological sample for analysis |
WO2015193076A1 (en) * | 2014-06-16 | 2015-12-23 | Koninklijke Philips N.V. | Cartridge for fast sample intake |
WO2016001933A1 (en) * | 2014-07-03 | 2016-01-07 | Fertilesafe Ltd | Device for preparing a biological sample for vitrification, and a method for utilizing it |
WO2016140379A1 (ko) * | 2015-03-04 | 2016-09-09 | 계명대학교 산학협력단 | 세포 급속 냉동을 위한 폴리머 미세 모세관 및 세포 트랩이 가능한 미세 모세관 |
CN108135155A (zh) * | 2015-10-13 | 2018-06-08 | 佛泰尔塞夫股份有限公司 | 制备用于低温程序的生物样品的装置及方法 |
RU164979U1 (ru) * | 2016-02-29 | 2016-09-27 | Общество с ограниченной ответственностью "ТюменНИИгипрогаз" | Фильтрующее устройство |
CN105831105B (zh) * | 2016-04-12 | 2018-12-14 | 上海理工大学 | 微流体细胞处理芯片及其应用方法 |
-
2018
- 2018-04-20 KR KR1020197033822A patent/KR102615574B1/ko active IP Right Grant
- 2018-04-20 KR KR1020237043090A patent/KR20230172627A/ko active Search and Examination
- 2018-04-20 BR BR112019022066-6A patent/BR112019022066B1/pt active IP Right Grant
- 2018-04-20 JP JP2019557379A patent/JP7295028B2/ja active Active
- 2018-04-20 CN CN201880039625.5A patent/CN110769690B/zh active Active
- 2018-04-20 WO PCT/US2018/028672 patent/WO2018195496A1/en active Application Filing
- 2018-04-20 CN CN202210117840.0A patent/CN114532329B/zh active Active
- 2018-04-20 US US16/606,717 patent/US20200093122A1/en active Pending
- 2018-04-20 EP EP18723234.3A patent/EP3612025B1/en active Active
- 2018-04-20 EP EP23174470.7A patent/EP4233542A3/en active Pending
-
2023
- 2023-06-08 JP JP2023094705A patent/JP2023123549A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002055673A1 (en) * | 2001-01-10 | 2002-07-18 | Biopore, Inc. | Cell concentrator and washer |
WO2013098825A1 (en) * | 2012-01-01 | 2013-07-04 | A.A. Cash Technology Ltd | Cryopreservation device for vitrification and method for using same |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2022025092A1 (ja) * | 2020-07-28 | 2022-02-03 | 国立大学法人山梨大学 | 凍結卵培養装置及び凍結卵の培養方法 |
Also Published As
Publication number | Publication date |
---|---|
CN114532329A (zh) | 2022-05-27 |
KR102615574B1 (ko) | 2023-12-18 |
EP3612025B1 (en) | 2023-06-28 |
BR112019022066B1 (pt) | 2024-04-30 |
KR20230172627A (ko) | 2023-12-22 |
CN114532329B (zh) | 2023-11-28 |
RU2019136692A3 (ja) | 2021-09-03 |
WO2018195496A1 (en) | 2018-10-25 |
JP7295028B2 (ja) | 2023-06-20 |
EP4233542A2 (en) | 2023-08-30 |
RU2019136692A (ru) | 2021-05-21 |
EP3612025A1 (en) | 2020-02-26 |
CN110769690B (zh) | 2022-02-25 |
US20200093122A1 (en) | 2020-03-26 |
KR20190140978A (ko) | 2019-12-20 |
BR112019022066A2 (pt) | 2020-05-05 |
EP4233542A3 (en) | 2023-11-22 |
JP2023123549A (ja) | 2023-09-05 |
CN110769690A (zh) | 2020-02-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7295028B2 (ja) | サンプルを調製するためのガラス化デバイス及び方法 | |
JP6799043B2 (ja) | 生物体液の極微標本管理装置 | |
ES2372169T3 (es) | Método y aparato de empotramiento rápido de bloques con células. | |
US5356814A (en) | Disaggregation device for cytological specimens | |
KR20170012281A (ko) | 생물학적 샘플로부터 생체분자를 수집, 운송 및 저장하기 위한 디바이스 | |
EP2279238A2 (en) | Flat cell carriers with cell traps | |
EP1520139A1 (en) | Changing the temperature of a liquid sample and a receptacle useful therefor | |
BR112020016868A2 (pt) | Dispositivo de coleta de fluido biológico e módulo de coleta | |
RU2019100237A (ru) | Набор и способ скрининга | |
CN110869486A (zh) | 微组织区室装置 | |
US20080185386A1 (en) | Changing the temperature of a liquid sample and a receptacle useful therefor | |
FR3034519A1 (fr) | Dispositif, kit et procede de prelevement et de traitement d'un echantillon biologique | |
CN214339670U (zh) | 一种生物材料处理装置 | |
CA1168585A (en) | Embryos thawing by isosmolal mixture | |
RU2017133436A (ru) | Пробоприемник, контейнер для проб и способ их использования | |
JP2023041884A (ja) | 生体液試料を回収する方法および生体液回収デバイス | |
US20160153966A1 (en) | Method For Handheld Diagnostics And Assays | |
RU2781072C2 (ru) | Устройство для витрификации и способ получения образца | |
CN114762498B (zh) | 一种生物材料处理装置 | |
WO2018069756A1 (en) | Devices and methods for warming of a cryopreserved biological sample | |
JP2019174188A (ja) | 試薬カートリッジ、核酸抽出セットおよび溶液廃棄方法 | |
CN212325242U (zh) | 一种细胞冷冻辅助装置 | |
KR102145842B1 (ko) | 정확한 관찰이 용이한 신속한 세포배양검사 장치 | |
BR112020021127A2 (pt) | sistema de coleta de fluido biológico | |
JP2020108336A (ja) | 生体細胞粒状凍結体作成具 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20210416 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20220131 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20220215 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20220513 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220815 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20221206 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230303 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20230509 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20230608 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7295028 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |