JP2019089762A5 - - Google Patents
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- Publication number
- JP2019089762A5 JP2019089762A5 JP2018219226A JP2018219226A JP2019089762A5 JP 2019089762 A5 JP2019089762 A5 JP 2019089762A5 JP 2018219226 A JP2018219226 A JP 2018219226A JP 2018219226 A JP2018219226 A JP 2018219226A JP 2019089762 A5 JP2019089762 A5 JP 2019089762A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 1
Claims (1)
- 式：
２２、
２８、
ＩＶ、
１１、
１５、
１６、
、
、
２６、
２７、
３０、
３１、
３２、
３４、
３６、
３７、
４３、または
４４
を有する化合物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779619P | 2013-03-13 | 2013-03-13 | |
| US61/779,619 | 2013-03-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018044050A Division JP2018150298A (ja) | 2013-03-13 | 2018-03-12 | ベンゾオキサゼピン化合物の作製方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019089762A JP2019089762A (ja) | 2019-06-13 |
| JP2019089762A5 true JP2019089762A5 (ja) | 2019-10-10 |
Family
ID=50241450
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562108A Active JP6363120B2 (ja) | 2013-03-13 | 2014-03-12 | ベンゾオキサゼピン化合物の作製方法 |
| JP2017135083A Active JP6442005B2 (ja) | 2013-03-13 | 2017-07-10 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018044050A Pending JP2018150298A (ja) | 2013-03-13 | 2018-03-12 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018153231A Active JP6663459B2 (ja) | 2013-03-13 | 2018-08-16 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018219226A Pending JP2019089762A (ja) | 2013-03-13 | 2018-11-22 | ベンゾオキサゼピン化合物の作製方法 |
| JP2020032846A Pending JP2020114814A (ja) | 2013-03-13 | 2020-02-28 | ベンゾオキサゼピン化合物の作製方法 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562108A Active JP6363120B2 (ja) | 2013-03-13 | 2014-03-12 | ベンゾオキサゼピン化合物の作製方法 |
| JP2017135083A Active JP6442005B2 (ja) | 2013-03-13 | 2017-07-10 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018044050A Pending JP2018150298A (ja) | 2013-03-13 | 2018-03-12 | ベンゾオキサゼピン化合物の作製方法 |
| JP2018153231A Active JP6663459B2 (ja) | 2013-03-13 | 2018-08-16 | ベンゾオキサゼピン化合物の作製方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020032846A Pending JP2020114814A (ja) | 2013-03-13 | 2020-02-28 | ベンゾオキサゼピン化合物の作製方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9303043B2 (ja) |
| EP (3) | EP3404032A3 (ja) |
| JP (6) | JP6363120B2 (ja) |
| KR (3) | KR101821468B1 (ja) |
| CN (2) | CN108929333A (ja) |
| AR (1) | AR095365A1 (ja) |
| AU (3) | AU2014230812B2 (ja) |
| BR (1) | BR112015020716A2 (ja) |
| CA (6) | CA2948763C (ja) |
| HK (1) | HK1215433A1 (ja) |
| IL (1) | IL240793A0 (ja) |
| MX (1) | MX2015011438A (ja) |
| NZ (1) | NZ711192A (ja) |
| RU (2) | RU2018109979A (ja) |
| SG (2) | SG10201706760YA (ja) |
| WO (1) | WO2014140073A1 (ja) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3083640A1 (en) | 2013-12-16 | 2016-10-26 | F. Hoffmann-La Roche AG | Polymorphs of 2-(4-(2-(1-isopropyl-3-methyl-1h-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1h-pyrazol-1-yl)-2-methylpropanamide, methods of production, and pharmaceutical uses thereof |
| US9650393B2 (en) | 2015-07-02 | 2017-05-16 | Genentech, Inc. | Benzoxazepin oxazolidinone compounds and methods of use |
| EP3317283B1 (en) | 2015-07-02 | 2019-04-03 | H. Hoffnabb-La Roche Ag | Benzoxazepin oxazolidinone compounds and methods of use |
| CN105906635A (zh) * | 2016-06-08 | 2016-08-31 | 上海大学 | 全氟烷基苯并氮杂*并喹喔啉衍生物及其合成方法 |
| JP7036724B2 (ja) * | 2016-07-29 | 2022-03-15 | 日本たばこ産業株式会社 | ピラゾール－アミド化合物の製造方法 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| KR102537048B1 (ko) | 2016-12-15 | 2023-05-26 | 에프. 호프만-라 로슈 아게 | (S)-2-((2-((S)-4-(다이플루오로메틸)-2-옥소옥사졸리딘-3-일)-5,6-다이하이드로벤조[f]이미다조[1,2-d][1,4]옥사제핀-9-일)아미노) 프로판아미드의 제조 방법 |
| CN108752237A (zh) * | 2018-07-05 | 2018-11-06 | 四川青木制药有限公司 | 一种对氨基苯甲脒盐酸盐的新制备方法 |
| SG11202106635WA (en) | 2018-12-21 | 2021-07-29 | Daiichi Sankyo Co Ltd | Combination of antibody-drug conjugate and kinase inhibitor |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5846824A (en) | 1994-02-07 | 1998-12-08 | Ludwig Institute For Cancer Research | Polypeptides having kinase activity, their preparation and use |
| US6274327B1 (en) | 1992-04-13 | 2001-08-14 | Ludwig Institute For Cancer Research | Polypeptides having kinase activity, their preparation and use |
| GB9208135D0 (en) | 1992-04-13 | 1992-05-27 | Ludwig Inst Cancer Res | Polypeptides having kinase activity,their preparation and use |
| WO2000024720A1 (en) * | 1998-10-23 | 2000-05-04 | Dow Agrosciences Llc | 3-(substituted phenyl)-5-(substituted cyclopropyl)-1,2,4-triazole compounds |
| CA2453113A1 (en) | 2001-07-12 | 2003-01-23 | Avecia Limited | Microencapsulated catalyst, methods of preparation and methods of use thereof |
| MXPA04002931A (es) * | 2001-10-12 | 2005-04-11 | Bayer Pharmaceuticals Corp | Heterociclos que contienen nitrogeno de 5 miembros sustituidos con fenilo para el tratamiento de la obesidad. |
| WO2007056170A2 (en) | 2005-11-02 | 2007-05-18 | Bayer Healthcare Ag | Pyrrolo[2,1-f] [1,2,4] triazin-4-ylamines igf-1r kinase inhibitors for the treatment of cancer and other hyperproliferative diseases |
| WO2008051805A2 (en) | 2006-10-23 | 2008-05-02 | Sgx Pharmaceuticals, Inc. | Triazolo-pyridazine protein kinase modulators |
| PT2084162E (pt) * | 2006-10-23 | 2012-10-09 | Sgx Pharmaceuticals Inc | Triazoles bicíclicos como moduladores de proteína quinase |
| CA2675755C (en) | 2007-01-19 | 2015-10-06 | Xcovery, Inc. | Pyridine and pyridazine derivatives as kinase inhibitors |
| JP5348725B2 (ja) * | 2007-10-25 | 2013-11-20 | ジェネンテック， インコーポレイテッド | チエノピリミジン化合物の製造方法 |
| US8716483B2 (en) * | 2008-02-21 | 2014-05-06 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
| ES2480994T3 (es) | 2008-03-31 | 2014-07-29 | Genentech, Inc. | Compuestos de tipo benzopirano y benzoxepina inhibidores de PI3K y métodos de uso |
| GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
| EP2784078A1 (en) | 2009-09-28 | 2014-10-01 | F. Hoffmann-La Roche AG | Benzoxepin pi3k inhibitor compounds and methods of use |
| RU2600927C2 (ru) * | 2009-09-28 | 2016-10-27 | Ф.Хоффманн-Ля Рош Аг | Бензоксазепиновые ингибиторы pi3k и способы применения |
| CA2778684A1 (en) * | 2009-10-29 | 2011-05-05 | Schering Corporation | Bridged bicyclic piperidine derivatives and methods of use thereof |
| CN102558167A (zh) * | 2010-12-29 | 2012-07-11 | 中国医学科学院药物研究所 | Gk和ppar双重激动活性的噻唑烷二酮衍生物 |
| WO2012126901A1 (en) * | 2011-03-21 | 2012-09-27 | F. Hoffmann-La Roche Ag | Benzoxazepin compounds selective for pi3k p110 delta and methods of use |
| NO3175985T3 (ja) * | 2011-07-01 | 2018-04-28 | ||
| BR112014028376A2 (pt) * | 2012-06-08 | 2018-04-24 | Hoffmann La Roche | métodos para o tratamento de um distúrbio hiperproliferativo, para a determinação dos compostos, para monitorar, para optimizar a eficácia terapêutica e de identificação de um biomarcador; formulação farmacêutica; utilização de uma combinação terapêutica e de gdc-0032, artigo de manufatura, produto e invenção |
-
2014
- 2014-03-12 BR BR112015020716A patent/BR112015020716A2/pt not_active Application Discontinuation
- 2014-03-12 EP EP18173513.5A patent/EP3404032A3/en active Pending
- 2014-03-12 CA CA2948763A patent/CA2948763C/en not_active Expired - Fee Related
- 2014-03-12 KR KR1020157024484A patent/KR101821468B1/ko active IP Right Grant
- 2014-03-12 CA CA2897618A patent/CA2897618A1/en not_active Abandoned
- 2014-03-12 CA CA3005103A patent/CA3005103A1/en not_active Abandoned
- 2014-03-12 RU RU2018109979A patent/RU2018109979A/ru not_active Application Discontinuation
- 2014-03-12 RU RU2015138488A patent/RU2649976C2/ru not_active IP Right Cessation
- 2014-03-12 SG SG10201706760YA patent/SG10201706760YA/en unknown
- 2014-03-12 AU AU2014230812A patent/AU2014230812B2/en not_active Ceased
- 2014-03-12 SG SG11201507394RA patent/SG11201507394RA/en unknown
- 2014-03-12 CA CA3005118A patent/CA3005118A1/en not_active Abandoned
- 2014-03-12 NZ NZ711192A patent/NZ711192A/en not_active IP Right Cessation
- 2014-03-12 US US14/205,634 patent/US9303043B2/en active Active
- 2014-03-12 CA CA3005112A patent/CA3005112A1/en not_active Abandoned
- 2014-03-12 CN CN201810489045.8A patent/CN108929333A/zh active Pending
- 2014-03-12 MX MX2015011438A patent/MX2015011438A/es unknown
- 2014-03-12 KR KR1020187016976A patent/KR20180070715A/ko not_active Application Discontinuation
- 2014-03-12 CN CN201480015055.8A patent/CN105377856B/zh active Active
- 2014-03-12 AR ARP140100904A patent/AR095365A1/es unknown
- 2014-03-12 EP EP20204345.1A patent/EP3845540A1/en active Pending
- 2014-03-12 EP EP14709314.0A patent/EP2970329A1/en not_active Withdrawn
- 2014-03-12 JP JP2015562108A patent/JP6363120B2/ja active Active
- 2014-03-12 KR KR1020177016062A patent/KR101871133B1/ko active IP Right Grant
- 2014-03-12 WO PCT/EP2014/054786 patent/WO2014140073A1/en active Application Filing
- 2014-03-12 CA CA2948765A patent/CA2948765A1/en not_active Abandoned
-
2015
- 2015-08-24 IL IL240793A patent/IL240793A0/en unknown
-
2016
- 2016-03-23 HK HK16103386.8A patent/HK1215433A1/zh unknown
- 2016-06-28 AU AU2016204432A patent/AU2016204432B2/en not_active Ceased
-
2017
- 2017-07-10 JP JP2017135083A patent/JP6442005B2/ja active Active
-
2018
- 2018-02-27 AU AU2018201393A patent/AU2018201393A1/en not_active Abandoned
- 2018-03-12 JP JP2018044050A patent/JP2018150298A/ja active Pending
- 2018-08-16 JP JP2018153231A patent/JP6663459B2/ja active Active
- 2018-11-22 JP JP2018219226A patent/JP2019089762A/ja active Pending
-
2020
- 2020-02-28 JP JP2020032846A patent/JP2020114814A/ja active Pending