JP2018020104A - 吻合の部位における狭窄の予防のための装置および方法 - Google Patents
吻合の部位における狭窄の予防のための装置および方法 Download PDFInfo
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Abstract
Description
本願は、2010年1月27日に出願された米国仮特許出願第61/298,631号への優先権を主張する。
本発明は一般的に、吻合の部位およびその周囲における狭窄を予防、抑制または処置するために有用な治療移植片、装置および方法に関する。加えて本発明は、吻合またはフィステルへの配置のために特定的に構成されたステント、ならびにそれらの部位をマトリックス材料および治療剤を含む血管外治療移植片と組み合わせるための方法にも関する。この特定的に構成されたステントは、吻合から離れた狭窄または狭小化の処置にも有用であり、たとえば側枝における小孔狭窄の処置、中心静脈(例、橈側皮アーチ(cephalic arch))における狭窄の処置などにも有用である。
方法:ヒツジモデルを用いて原理研究の証明を行った。6mmのPTFE血管グラフトを、一方側の頸動脈と反対側の頸静脈との間で吻合し、ヒトの血液透析アクセスループと類似の構成の動脈静脈(AV)ループグラフトを作製した。合計4匹の動物の研究を行い、2匹の動物(2つのAVグラフト)はPTFEグラフト−静脈吻合に血管内自己拡張型ニチノールステントを受け取り、他方の2匹の動物(2つのAVグラフト)はPTFE−静脈グラフト吻合に血管内自己拡張型ニチノールステントと、血管周囲シロリムス(ラパマイシン)溶出コラーゲンマトリックスとを受け取った。シロリムス溶出コラーゲンマトリックスはPTFEグラフト静脈吻合の場所の外表面に移植されることによって、外部面のマトリックスが血管内のニチノール血管内ステントの場所にほぼ対応するようにされた。使用されたステントは自己拡張型ニチノールステントであり、長さは30mm、完全に拡張されたときの直径は8.0mmであった。コラーゲンマトリックスは既知用量のシロリムス(およそ75マイクログラム/cm2)と組み合わされた。
結論:
1.狭小化の程度(%ステント直径狭窄)は、ステントおよび薬物溶出性ステントマトリックスの両方を受け取った動物よりも、薬物溶出コラーゲンマトリックスを伴わずにステントを受け取った動物の方が高い。
方法:ヒツジ動脈−静脈フィステルモデルを用いて原理研究の証明を行った。大腿静脈を大腿動脈に、(静脈の)端部から(動脈の)側部への様式で吻合することによって、両側性の動脈静脈フィステルを作製した。吻合の方法(端部から側部)は、ヒトにおいて透析アクセスを提供するために作製されるAVフィステルの構成(例、橈骨−橈側皮(radio−cephalic)、上腕−橈側皮)を模倣するものである。血管内ステントに加えて血管周囲の薬物溶出(例、シロリムス)を用いるという概念は、他の吻合構成(例、端部から端部、側部から側部など)、および静脈と動脈とが吻合されるその他の手術(例、冠状動脈バイパスグラフト手術、末梢血管バイパス手術)または2本の導管が吻合されるその他の手術(例、卵管、尿管、胆管、気管支気道、腸係蹄など)にも適用可能である。対照フィステルは、血管内自己拡張型ニチノールステントも血管周囲シロリムス(ラパマイシン)溶出コラーゲンマトリックスも受け取らなかった。処置フィステルは、吻合から始まって流出静脈に延在する(この場合は吻合近傍セグメントにわたる)血管内自己拡張型ニチノールステントと、血管周囲シロリムス(ラパマイシン)溶出コラーゲンマトリックスとを受け取った。シロリムス溶出コラーゲンマトリックスはフィステルの外表面に移植されることによって、外部面のマトリックスが血管内のニチノール血管内ステントの吻合場所にほぼ対応するようにされた。加えてシロリムス溶出マトリックスは、マトリックスが吻合の場所の動脈と静脈との両方を包むように吻合に移植された。下に考察される例示的実施例は、長さが30mmまたは40mmで完全に拡張されたときの直径が6mmである自己拡張型ステントの使用を示す。コラーゲンマトリックスは既知用量のシロリムス(およそ75マイクログラム/cm2)と組み合わされた。
1.対照動物(血管内ステントも血管周囲シロリムス溶出コラーゲンマトリックスも無)における動脈−静脈フィステルの28日後の血管造影図は、吻合および流出静脈の吻合近傍セグメントにおける重篤な狭窄を示す。この狭窄のパターンは、ヒトにおける状況(例、透析を支持するために作製された橈骨−橈側皮フィステルにおける狭窄、冠状動脈および末梢動脈バイパスグラフト手術における静脈グラフトの吻合狭窄)を模倣している。
Claims (18)
- 血管吻合部位における狭窄を予防するための、抗血管増殖薬を吸収させた生細胞及び粘着性の両方がない生体適合性マトリックス材料であって、
血管の内腔内に配置された薬物のないステントと組み合わせて用いられ、
前記血管の血管外表面に適用されたスリーブに形成される、生体適合性マトリックス材料。 - 前記血管吻合部位は、動脈、静脈又はグラフトの一部である、請求項1に記載の生体適合性マトリックス材料。
- 前記ステントは自己拡張型ステントである、請求項1に記載の生体適合性マトリックス材料。
- 前記ステントはバルーン拡張可能型ステントである、請求項1に記載の生体適合性マトリックス材料。
- 前記ステントはベアメタルのステントである、請求項1に記載の生体適合性マトリックス材料。
- 前記ステントは、ポリマー又は織物によって部分的に又は完全に覆われている、請求項1に記載の生体適合性マトリックス材料。
- 前記ステントは、PTFEにより覆われている、請求項6に記載の生体適合性マトリックス材料。
- 前記マトリックス材料は、コラーゲン、フィブリン、多糖、およびそれらの混合物からなる群より選択される、請求項1に記載の生体適合性マトリックス材料。
- 前記多糖はキトサンである、請求項8に記載の生体適合性マトリックス材料。
- 前記マトリックス材料はコラーゲンを含む、請求項8に記載の生体適合性マトリックス材料。
- 前記コラーゲンは、I型、II型、III型、IV型、XI型、およびそれらの混合物からなる群より選択される、請求項10に記載の生体適合性マトリックス材料。
- 前記コラーゲンはI型ウシコラーゲンである、請求項11に記載の生体適合性マトリックス材料。
- 前記ステントは吻合部位に配置するために長手軸に沿って湾曲している、請求項8に記載の生体適合性マトリックス材料。
- 前記マトリックス材料に吸収された前記抗血管増殖薬はラパマイシンである、請求項1に記載の生体適合性マトリックス材料。
- 前記マトリックス材料に吸収された前記抗血管増殖薬はラパマイシンのアナログである、請求項1に記載の生体適合性マトリックス材料。
- 前記ラパマイシンの前記アナログはエベロリムス又はゾタロリムスである、請求項15に記載の生体適合性マトリックス材料。
- 前記生体適合性マトリックス材料に吸収された有効成分は、抗血管増殖薬のみからなる、請求項1に記載の生体適合性マトリックス材料。
- 前記マトリックス材料に吸収された前記抗血管増殖薬は、ラパマイシン又はラパマイシンのアナログである、請求項17に記載の生体適合性マトリックス材料。
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2019150584A (ja) * | 2010-01-27 | 2019-09-12 | バスキュラー・セラピーズ・インコーポレイテッド | 吻合の部位における狭窄の予防のための装置および方法 |
WO2024024946A1 (ja) * | 2022-07-29 | 2024-02-01 | 慶應義塾 | 吻合補助具 |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0419954D0 (en) | 2004-09-08 | 2004-10-13 | Advotek Medical Devices Ltd | System for directing therapy |
US20130190676A1 (en) | 2006-04-20 | 2013-07-25 | Limflow Gmbh | Devices and methods for fluid flow through body passages |
US9017323B2 (en) | 2010-11-16 | 2015-04-28 | Tva Medical, Inc. | Devices and methods for forming a fistula |
KR101330397B1 (ko) * | 2011-11-01 | 2013-11-15 | 재단법인 아산사회복지재단 | 자가 팽창성을 가지는 물질 또는 구조를 이용한 혈관 문합용 구조물 및 이를 이용한 혈관 문합 방법 |
WO2013114358A1 (en) * | 2012-01-30 | 2013-08-08 | Hipokrat | Negatively charged vascular stent |
US8840678B2 (en) * | 2012-02-10 | 2014-09-23 | Abbott Cardiovascular Systems Inc. | Drug-eluting bioabsorbable renal artery stent for renal cancer and inflammatory disorders |
WO2013192208A1 (en) * | 2012-06-18 | 2013-12-27 | Board Of Regents Of The University Of Nebraska | Stent to assist in arteriovenous fistula formation |
US9486276B2 (en) | 2012-10-11 | 2016-11-08 | Tva Medical, Inc. | Devices and methods for fistula formation |
US10835367B2 (en) | 2013-03-08 | 2020-11-17 | Limflow Gmbh | Devices for fluid flow through body passages |
AU2014226234B2 (en) | 2013-03-08 | 2017-12-07 | Limflow Gmbh | Methods and systems for providing or maintaining fluid flow through body passages |
CN105228683B (zh) | 2013-03-14 | 2022-06-10 | Tva医疗公司 | 瘘管形成装置和用于形成瘘管的方法 |
EP2898920B1 (en) | 2014-01-24 | 2018-06-06 | Cook Medical Technologies LLC | Articulating balloon catheter |
WO2015138998A1 (en) | 2014-03-14 | 2015-09-17 | Tva Medical, Inc. | Fistula formation devices and methods therefor |
US9687239B2 (en) | 2014-04-15 | 2017-06-27 | Abbott Cardiovascular Systems Inc. | Intravascular devices supporting an arteriovenous fistula |
US9545263B2 (en) | 2014-06-19 | 2017-01-17 | Limflow Gmbh | Devices and methods for treating lower extremity vasculature |
US20160007997A1 (en) * | 2014-07-14 | 2016-01-14 | Chengxiong Gu | Bridge vessels-proximal anastomosis supporting device for coronary artery bypass grafting and manufacturing method thereof |
US10646666B2 (en) | 2014-08-27 | 2020-05-12 | Tva Medical, Inc. | Cryolipolysis devices and methods therefor |
US10603040B1 (en) | 2015-02-09 | 2020-03-31 | Tva Medical, Inc. | Methods for treating hypertension and reducing blood pressure with formation of fistula |
CN106333722A (zh) * | 2015-07-10 | 2017-01-18 | 洛克斯医药公司 | 用于创建血液流动通路以治疗患者的方法、***和装置 |
WO2017011402A1 (en) * | 2015-07-10 | 2017-01-19 | Rox Medical, Inc. | Methods, systems and devices for creating a blood flow pathway to treat a patient |
WO2017040366A1 (en) * | 2015-08-28 | 2017-03-09 | University Of Cincinnati | Arteriovenous fistula implant effective for inducing laminar blood flow |
EP4299099A3 (en) | 2016-01-15 | 2024-04-03 | TVA Medical, Inc. | Devices for advancing a wire |
US11026743B2 (en) | 2016-01-15 | 2021-06-08 | Tva Medical, Inc. | Devices and methods for forming a fistula |
US10874422B2 (en) | 2016-01-15 | 2020-12-29 | Tva Medical, Inc. | Systems and methods for increasing blood flow |
CN109982652B (zh) | 2016-09-25 | 2022-08-05 | Tva医疗公司 | 血管支架装置和方法 |
EP3609415B1 (en) | 2017-04-10 | 2023-08-23 | LimFlow GmbH | Devices for treating lower extremity vasculature |
JP7466531B2 (ja) | 2018-10-09 | 2024-04-12 | リムフロウ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | カテーテル位置合わせ装置及び方法 |
WO2020185851A1 (en) * | 2019-03-11 | 2020-09-17 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Anastomosing stent and methods of use |
AU2020373046A1 (en) | 2019-11-01 | 2022-05-12 | Limflow Gmbh | Devices and methods for increasing blood perfusion to a distal extremity |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1119219A (ja) * | 1997-03-10 | 1999-01-26 | Cordis Corp | ステント |
JP2002540822A (ja) * | 1999-03-19 | 2002-12-03 | ボストン サイエンティフィック リミテッド | ポリマー被覆形ステント |
JP2009119257A (ja) * | 2001-01-16 | 2009-06-04 | Vascular Therapies Llc | 吸収可能なマトリックス材料および抗増殖薬を含む、血液透析血管アクセス及び他の血管移植片の機能不全を防止又は治療するための移植可能な装置および方法 |
Family Cites Families (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE445884B (sv) | 1982-04-30 | 1986-07-28 | Medinvent Sa | Anordning for implantation av en rorformig protes |
US4733665C2 (en) | 1985-11-07 | 2002-01-29 | Expandable Grafts Partnership | Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft |
SE453258B (sv) | 1986-04-21 | 1988-01-25 | Medinvent Sa | Elastisk, sjelvexpanderande protes samt forfarande for dess framstellning |
US5019085A (en) * | 1988-10-25 | 1991-05-28 | Cordis Corporation | Apparatus and method for placement of a stent within a subject vessel |
CH678393A5 (ja) | 1989-01-26 | 1991-09-13 | Ulrich Prof Dr Med Sigwart | |
US5425739A (en) * | 1989-03-09 | 1995-06-20 | Avatar Design And Development, Inc. | Anastomosis stent and stent selection system |
US5545208A (en) | 1990-02-28 | 1996-08-13 | Medtronic, Inc. | Intralumenal drug eluting prosthesis |
ATE247435T1 (de) | 1992-05-08 | 2003-09-15 | Schneider Usa Inc | Stent für den oesophagus |
US6090115A (en) * | 1995-06-07 | 2000-07-18 | Intratherapeutics, Inc. | Temporary stent system |
JP3507503B2 (ja) * | 1995-03-10 | 2004-03-15 | インプラ・インコーポレーテッド | 体腔内用の封止型ステント及びその製造方法並びにその体腔内への導入方法 |
DE69635112T2 (de) * | 1995-07-07 | 2006-05-18 | W.L. Gore & Associates, Inc., Newark | Innenbeschichtung für rohre und blutgefässe |
US20040106985A1 (en) * | 1996-04-26 | 2004-06-03 | Jang G. David | Intravascular stent |
US6726933B2 (en) | 1996-09-30 | 2004-04-27 | Shiseido Co., Ltd. | Rod-shaped mesoporous powder, humectant adsorbing powder, and cosmetic preparation using the same |
US6019788A (en) * | 1996-11-08 | 2000-02-01 | Gore Enterprise Holdings, Inc. | Vascular shunt graft and junction for same |
US6026814A (en) * | 1997-03-06 | 2000-02-22 | Scimed Life Systems, Inc. | System and method for percutaneous coronary artery bypass |
US6273913B1 (en) | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
US5957929A (en) * | 1997-05-02 | 1999-09-28 | Micro Therapeutics, Inc. | Expandable stent apparatus and method |
US6165195A (en) * | 1997-08-13 | 2000-12-26 | Advanced Cardiovascylar Systems, Inc. | Stent and catheter assembly and method for treating bifurcations |
US6330884B1 (en) * | 1997-11-14 | 2001-12-18 | Transvascular, Inc. | Deformable scaffolding multicellular stent |
JP4187411B2 (ja) * | 1998-01-30 | 2008-11-26 | セント ジュード メディカル エーティージー, インコーポレイテッド | 中隔欠損を閉じる際に使用するためのデバイス |
AU4679499A (en) * | 1998-06-10 | 1999-12-30 | Advanced Bypass Technologies, Inc. | Thermal securing anastomosis systems |
US20020019660A1 (en) * | 1998-09-05 | 2002-02-14 | Marc Gianotti | Methods and apparatus for a curved stent |
US6152937A (en) * | 1998-11-06 | 2000-11-28 | St. Jude Medical Cardiovascular Group, Inc. | Medical graft connector and methods of making and installing same |
US7025773B2 (en) * | 1999-01-15 | 2006-04-11 | Medtronic, Inc. | Methods and devices for placing a conduit in fluid communication with a target vessel |
US7578828B2 (en) * | 1999-01-15 | 2009-08-25 | Medtronic, Inc. | Methods and devices for placing a conduit in fluid communication with a target vessel |
WO2001049338A1 (en) | 1999-12-30 | 2001-07-12 | Li Wei Pin | Controlled delivery of therapeutic agents by insertable medical devices |
US20160287708A9 (en) * | 2000-03-15 | 2016-10-06 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
US20020052572A1 (en) * | 2000-09-25 | 2002-05-02 | Kenneth Franco | Resorbable anastomosis stents and plugs and their use in patients |
US6579308B1 (en) * | 2000-11-28 | 2003-06-17 | Scimed Life Systems, Inc. | Stent devices with detachable distal or proximal wires |
JP2002272855A (ja) * | 2001-03-14 | 2002-09-24 | Piolax Medical Device:Kk | ステント |
DE60104647T2 (de) * | 2001-03-27 | 2005-08-11 | William Cook Europe Aps | Gefässtransplantat für die Aorta |
US6716238B2 (en) * | 2001-05-10 | 2004-04-06 | Scimed Life Systems, Inc. | Stent with detachable tethers and method of using same |
US7115136B2 (en) * | 2001-06-20 | 2006-10-03 | Park Medical Llc | Anastomotic device |
WO2003009778A2 (en) * | 2001-07-26 | 2003-02-06 | Avantec Vascular Corporation | Methods and devices for delivery of therapeutic capable agents with variable release profile |
US20060224234A1 (en) * | 2001-08-29 | 2006-10-05 | Swaminathan Jayaraman | Drug eluting structurally variable stent |
US7108701B2 (en) * | 2001-09-28 | 2006-09-19 | Ethicon, Inc. | Drug releasing anastomosis devices and methods for treating anastomotic sites |
US7758881B2 (en) * | 2004-06-30 | 2010-07-20 | Advanced Cardiovascular Systems, Inc. | Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device |
WO2004100836A1 (en) * | 2003-05-12 | 2004-11-25 | Cook Incorporated | Stent graft |
US7226473B2 (en) * | 2003-05-23 | 2007-06-05 | Brar Balbir S | Treatment of stenotic regions |
ES2452731T3 (es) * | 2003-06-19 | 2014-04-02 | Vascular Therapies, Llc | Dispositivo de cierre vascular |
JP2005211293A (ja) * | 2004-01-29 | 2005-08-11 | Piolax Medical Device:Kk | 管状器官の治療具 |
US20050203606A1 (en) * | 2004-03-09 | 2005-09-15 | Vancamp Daniel H. | Stent system for preventing restenosis |
US20050278013A1 (en) * | 2004-05-26 | 2005-12-15 | Matthew Rust | Method for endovascular bypass stent graft delivery |
CN101940801B (zh) * | 2004-12-08 | 2014-04-16 | 夏尔再生医学公司 | 增强血管通路的方法和组合物 |
JP4979591B2 (ja) * | 2005-01-10 | 2012-07-18 | トライレム メディカル, インコーポレイテッド | 自己展開可能な部分を有するステント |
US9101500B2 (en) * | 2005-01-10 | 2015-08-11 | Trireme Medical, Inc. | Stent with self-deployable portion having wings of different lengths |
EP1933785B1 (en) * | 2005-10-14 | 2015-04-22 | Abbott Laboratories | Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices |
CN101045022B (zh) * | 2006-03-30 | 2010-08-25 | 温宁 | 自扩型支架轴向拉线张紧机构 |
US7722665B2 (en) * | 2006-07-07 | 2010-05-25 | Graft Technologies, Inc. | System and method for providing a graft in a vascular environment |
WO2008042266A2 (en) * | 2006-09-28 | 2008-04-10 | Cook Incorporated | Thoracic aortic aneurysm repair apparatus and method |
US7914552B2 (en) * | 2006-11-09 | 2011-03-29 | Ethicon Endo-Surgery, Inc. | Method of performing an end-to-end anastomosis using a stent and an adhesive |
US20090024068A1 (en) * | 2007-07-16 | 2009-01-22 | Hemcon Medical Technologies, Inc. | Absorbable tissue dressing assemblies, systems, and methods formed from a Hydrophilic chitosan sponge structure and including a flexible absorbable backing layer of poly-4-hydroxy butyrate |
US20090110713A1 (en) * | 2007-10-31 | 2009-04-30 | Florencia Lim | Biodegradable polymeric materials providing controlled release of hydrophobic drugs from implantable devices |
US8303650B2 (en) * | 2008-01-10 | 2012-11-06 | Telesis Research, Llc | Biodegradable self-expanding drug-eluting prosthesis |
WO2011060249A2 (en) * | 2009-11-13 | 2011-05-19 | The Brigham And Women's Hospital, Inc. | Methods and apparatus for vascular anastomosis |
EP2528537A4 (en) * | 2010-01-27 | 2016-09-07 | Vascular Therapies Inc | DEVICE AND METHOD FOR STENOSIS PREVENTION AT AN ANASTOMOSE STATION |
US9345484B2 (en) * | 2010-11-11 | 2016-05-24 | Asfora Ip, Llc | Deployment tool for sutureless vascular anastomosis connection |
-
2011
- 2011-01-27 EP EP11737681.4A patent/EP2528537A4/en not_active Withdrawn
- 2011-01-27 JP JP2012551292A patent/JP6172704B2/ja active Active
- 2011-01-27 EP EP20197200.7A patent/EP3878403A1/en not_active Withdrawn
- 2011-01-27 WO PCT/US2011/022795 patent/WO2011094459A1/en active Application Filing
- 2011-01-27 US US13/015,571 patent/US20110319976A1/en not_active Abandoned
-
2013
- 2013-03-26 US US13/850,450 patent/US20140088681A1/en not_active Abandoned
-
2016
- 2016-10-03 US US15/284,234 patent/US20170020651A1/en not_active Abandoned
-
2017
- 2017-06-28 JP JP2017126119A patent/JP6506350B2/ja active Active
-
2019
- 2019-03-28 JP JP2019062179A patent/JP2019150584A/ja active Pending
-
2020
- 2020-08-03 US US16/983,893 patent/US20200360126A1/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1119219A (ja) * | 1997-03-10 | 1999-01-26 | Cordis Corp | ステント |
JP2002540822A (ja) * | 1999-03-19 | 2002-12-03 | ボストン サイエンティフィック リミテッド | ポリマー被覆形ステント |
JP2009119257A (ja) * | 2001-01-16 | 2009-06-04 | Vascular Therapies Llc | 吸収可能なマトリックス材料および抗増殖薬を含む、血液透析血管アクセス及び他の血管移植片の機能不全を防止又は治療するための移植可能な装置および方法 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2019150584A (ja) * | 2010-01-27 | 2019-09-12 | バスキュラー・セラピーズ・インコーポレイテッド | 吻合の部位における狭窄の予防のための装置および方法 |
WO2024024946A1 (ja) * | 2022-07-29 | 2024-02-01 | 慶應義塾 | 吻合補助具 |
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JP6506350B2 (ja) | 2019-04-24 |
JP6172704B2 (ja) | 2017-08-02 |
EP3878403A1 (en) | 2021-09-15 |
WO2011094459A1 (en) | 2011-08-04 |
EP2528537A4 (en) | 2016-09-07 |
JP2013517906A (ja) | 2013-05-20 |
EP2528537A1 (en) | 2012-12-05 |
US20140088681A1 (en) | 2014-03-27 |
US20170020651A1 (en) | 2017-01-26 |
JP2019150584A (ja) | 2019-09-12 |
US20200360126A1 (en) | 2020-11-19 |
US20110319976A1 (en) | 2011-12-29 |
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