JP2017515629A - ローリングダイヤフラムを備えたシリンジ - Google Patents
ローリングダイヤフラムを備えたシリンジ Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31513—Piston constructions to improve sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/14586—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of a flexible diaphragm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
- A61M5/2425—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
- A61M2005/14553—Front-loading type injectors comprising a pressure jacket
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14546—Front-loading type injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/14586—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of a flexible diaphragm
- A61M5/14593—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of a flexible diaphragm the diaphragm being actuated by fluid pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31515—Connection of piston with piston rod
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- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
本出願は、「Syringe With Rolling Diaphragm」という名称の2014年4月25日に出願された米国仮特許出願第61/984,386号明細書、および「Syringe With Rolling Diaphragm」という名称の2014年3月1日に出願された米国仮特許出願第61/987,086号明細書に対する優先権を主張し、それらの開示内容は全体として参照により本明細書に組み込まれる。
102 流体注入器
104 蝶番、単回使用シリンジ、シリンジ
108 流体流路セット
110 圧力ジャケット、再使用可能圧力ジャケット
110 円筒状半体、リップ、アダプタ
112 軸方向折目
114 内部容積
116 遠位端
118 近位端
119 側壁
120 内部側壁
121 貫通孔
122 取付機構
124 液体注入器面板
126 ハウジング
128 出口ポート
130 遠位端、ノズル
132 近位端
134 外側側壁、可撓性側壁
136 閉鎖端壁、近位端壁
138 ピストンヘッド、ピストン
140 排出首部
142 排出ポート
144 プランジャ、ピストン
145 中心部分
145’ 第1傾斜面
146 遠位端
147 半径方向伸張可能要素
147’ 第2傾斜面
147’’ 把持面
148 近位端
150 シール
151 基部
152 キャップ
153 側壁
154 コネクタ
155 穿孔要素
156 穿孔針、穿孔部材
157 本体
158 係止タブ
160 係止カラー
166 蝶番
168 閉鎖部材
170 部分
172 部分
174 スカート
176 折目
178 ピストン
180 流体充填空洞、エラストマー充填空洞
184 流体スリーブ
186 第2キャップ
188 弁
190 センサ
192 把持タブ
194 フィンガロック
196 可能閉鎖具
200 脆弱シール
202 高圧シール
204 低圧シール
206 溝
208 突起
210 部材
211 突起
212 接続部材
213 拡張可能リブ
214 拡張可能材料
215 ローラ
216 拡張可能バルーン
218 係合部材
220 支持要素
222 環状スリーブ、環状シュリンクラップスリーブ
223 加熱素子
224 開口部
226 折縁
228 カラー
230 プランジャ支持基部
232 接着剤層
234 ピストン係合要素
236 可能タブ
240 流体存在指標
242 環状部材
244 プランジャ係合部分
246 把持要素
248 枢動可能要素
250 共通枢支点
252 弾性要素
254 接続インタフェース、プランジャ係合部分
256 部分
258 カラー
260 プランジャ基部
262 遠位側壁
264 穿孔要素
266 シール
268 内側要素
270 外側要素
272 傾斜面
274 遠位部分
276 中心部分
278 リブ
280 カバー
282 本体
284 リップ
286 溝
288 環状***
290 ピン
300 内側要素
310 弾性要素
320 外側要素
330 タブ
340 スロット
350 半径方向フランジ
360 係止要素
370 リップ
390 キャップ
400 内側要素
410 ノズル
420 コネクタ
430 突起
440 溝、山
450 ポケット
Claims (19)
- 医療流体をその中に受け入れるローリングダイヤフラムであって、
プランジャと係合する端壁を備えた近位端と、圧力ジャケットの貫通孔内に受け入れられる遠位端であって、ノズルを有する遠位端と、長手方向軸に沿って前記近位端と前記遠位端との間に延在する側壁とを備え、前記側壁および前記端壁のうちの少なくとも一方の少なくとも一部が不均一な厚さを有し、
前記側壁が、前記プランジャによって作用されるとそれ自体の上で転動し、それにより、前記プランジャが前記近位端から前記遠位端に前進される際に、折畳み領域における前記側壁の外面が半径方向内側方向に折り畳まれるように、前記側壁の少なくとも一部が可撓性を有し、前記プランジャが前記近位端から前記遠位端に後退される際に、前記折畳み領域が半径方向外側方向に広げられる際に、前記側壁の前記外面が展開する、ローリングダイヤフラム。 - 前記端壁が、連続的に厚さが増大する遠位に延在する傾斜面に遷移する丸みがつけられた折縁を有する、請求項1に記載のローリングダイヤフラム。
- 前記端壁が、前記傾斜面の中心領域から近位に突出するプランジャ係合部分を有する、請求項2に記載のローリングダイヤフラム。
- 前記端壁が、前記プランジャ係合部分から前記丸みが付けられた折縁に向かって半径方向外側に突出する1つまたは複数のリブを有する、請求項3に記載のローリングダイヤフラム。
- 前記ローリングダイヤフラムのおよその中間点の遠位の前記側壁の第1部分が第1厚さを有し、前記ローリングダイヤフラムの前記およその中間点の近位の前記側壁の第2部分が第2厚さを有し、前記第1厚さが前記第2厚さより大きい、請求項1に記載のローリングダイヤフラム。
- 前記近位端が、前記近位端と一体的に形成された剛性プランジャを有する、請求項1に記載のローリングダイヤフラム。
- 前記プランジャ係合部分が、前記プランジャの開口部内に受け入れられる、請求項3に記載のローリングダイヤフラム。
- 前記プランジャ係合部分が、前記プランジャの少なくとも一部と取外し不可能に固定される、請求項7に記載のローリングダイヤフラム。
- 前記プランジャ係合部分の少なくとも一部は、前記プランジャ係合部分を前記プランジャの前記開口部内に保持するように、前記プランジャの前記開口部内に挿入された後に半径方向外側に拡張される、請求項7に記載のローリングダイヤフラム。
- 前記ローリングダイヤフラムの内部が、医療流体で予め充填される、請求項1に記載のローリングダイヤフラム。
- 前記ノズルが、流体流路セットに接続するコネクタを有する、請求項1に記載のローリングダイヤフラム。
- 前記コネクタがルアーコネクタである、請求項11に記載のローリングダイヤフラム。
- 前記ノズルが、前記ローリングダイヤフラムの内部を封止する穿孔可能なシールを有する、請求項1に記載のローリングダイヤフラム。
- 前記ノズルが、前記ノズルと前記ローリングダイヤフラムの前記側壁との間の第1シールと、前記ノズルを流体流路セットに接続するインタフェースにおける第2シールとを有する、請求項1に記載のローリングダイヤフラム。
- 流体送達システム用のシリンジであって、
遠位端、近位端、および前記遠位端と前記近位端との間に延在する貫通孔を有する圧力ジャケットと、
前記圧力ジャケットの前記貫通孔内に配置されたローリングダイヤフラムであって、プランジャと係合する端壁を有する近位端と、前記圧力ジャケットの前記遠位端において受け入れられる遠位端であって、ノズルを有する前記ローリングダイヤフラムの遠位端である遠位端と、長手方向軸に沿って前記ローリングダイヤフラムの前記近位端と前記遠位端との間に延在する側壁とを有し、前記端壁および前記側壁の少なくとも一部のうちの少なくとも一方が不均一な厚さを有する、ローリングダイヤフラムと
を備え、
前記ローリングダイヤフラムの前記側壁の少なくとも一部が、可撓性を有し、かつそれ自体の上で転動し、それにより、前記プランジャが前記ローリングダイヤフラムの前記近位端から前記遠位端に前進される際に、折畳み領域における前記側壁の外面が半径方向内側方向に折り畳まれ、および前記プランジャが前記ローリングダイヤフラムの前記近位端から前記遠位端に後退される際に、前記折畳み領域が半径方向外側方向に広げられる際に、前記側壁の前記外面が展開する、シリンジ。 - 前記圧力ジャケットが、前記ローリングダイヤフラムの少なくとも一部を囲む取外し可能閉鎖具を有する、請求項15に記載のシリンジ。
- 前記取外し可能閉鎖具が、前記圧力ジャケットの前記遠位端の対応するねじ山と係合するねじ切り端部を有するか、または前記取外し可能閉鎖具が、前記圧力ジャケットの前記遠位端のバヨネットロック機構と係合する対応するスロットに挿入される1つまたは複数の半径方向に伸張するタブを有する、請求項16に記載のシリンジ。
- 前記圧力ジャケットの前記近位端が、流体注入器に解除可能に接続する接続インタフェースを有する、請求項16に記載のシリンジ。
- 少なくとも1つの往復動作可能なピストンを備える流体注入器と、
前記ピストンに動作可能に接続可能なプランジャと、
遠位端、近位端、および前記遠位端と前記近位端との間に延在する貫通孔を有する圧力ジャケットであって、前記流体注入器に動作可能に接続可能な圧力ジャケットと、
前記圧力ジャケットの貫通孔内に配置されたローリングダイヤフラムであって、前記プランジャと係合する端壁を備えた近位端と、前記圧力ジャケットの前記遠位端において受け入れられる遠位端であって、ノズルを有する前記ローリングダイヤフラムの遠位端である遠位端と、長手方向軸に沿って前記ローリングダイヤフラムの前記近位端と前記遠位端との間に延在する側壁であって、前記側壁および前記端壁のうちの少なくとも一方の少なくとも一部が不均一な厚さを有する、側壁とを備える、ローリングダイヤフラムと
を備え、
前記ローリングダイヤフラムの前記側壁の少なくとも一部が、可撓性を有し、かつそれ自体の上で転動し、それにより、前記プランジャが前記ピストンにより前記ローリングダイヤフラムの前記近位端から前記遠位端に前進される際に、折畳み領域における前記側壁の外面が半径方向内側方向に折り畳まれ、および前記プランジャが前記ピストンにより前記ローリングダイヤフラムの前記近位端から前記遠位端に後退される際に、前記折畳み領域が半径方向外側方向に広げられる際に、前記側壁の前記外面が展開する、流体送達システム。
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JP2019203486A (ja) * | 2018-05-25 | 2019-11-28 | 日本ピラー工業株式会社 | ローリングダイアフラムポンプ |
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