JP2017149781A - Antimicrobial composition for wood - Google Patents
Antimicrobial composition for wood Download PDFInfo
- Publication number
- JP2017149781A JP2017149781A JP2017112925A JP2017112925A JP2017149781A JP 2017149781 A JP2017149781 A JP 2017149781A JP 2017112925 A JP2017112925 A JP 2017112925A JP 2017112925 A JP2017112925 A JP 2017112925A JP 2017149781 A JP2017149781 A JP 2017149781A
- Authority
- JP
- Japan
- Prior art keywords
- parts
- isothiazolin
- wood
- mixed
- ipbc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 47
- 239000002023 wood Substances 0.000 title claims abstract description 39
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- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 claims abstract description 39
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- JPMIIZHYYWMHDT-UHFFFAOYSA-N octhilinone Chemical compound CCCCCCCCN1SC=CC1=O JPMIIZHYYWMHDT-UHFFFAOYSA-N 0.000 claims abstract description 27
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- 150000004696 coordination complex Chemical class 0.000 claims abstract description 12
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- NFIDBGJMFKNGGQ-UHFFFAOYSA-N isopropylmethylphenol Natural products CC(C)CC1=CC=CC=C1O NFIDBGJMFKNGGQ-UHFFFAOYSA-N 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- JWZXKXIUSSIAMR-UHFFFAOYSA-N methylene bis(thiocyanate) Chemical compound N#CSCSC#N JWZXKXIUSSIAMR-UHFFFAOYSA-N 0.000 description 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 description 1
- 230000003641 microbiacidal effect Effects 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 235000010292 orthophenyl phenol Nutrition 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 229960003330 pentetic acid Drugs 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 229920000137 polyphosphoric acid Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 235000020354 squash Nutrition 0.000 description 1
- 150000008054 sulfonate salts Chemical class 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000004548 suspo-emulsion Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 239000004563 wettable powder Substances 0.000 description 1
- 229940043810 zinc pyrithione Drugs 0.000 description 1
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
木材および木材製品に対して、糸状菌だけでなく変色菌や担子菌を含む幅広い真菌から、少ない使用量で保護することが可能な木材用抗菌組成物に関するものであり、詳しくは５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と、３−ヨード−２−プロピニルブチルカーバメートと、一般式（Ｉ）で示される一種以上のイソチアゾロン化合物（ただし、５−クロロ−２−メチル−４−イソチアゾリン−３−オンを除く）またはベンズイミダゾール系化合物から選ばれる一種以上の化合物を必須成分として含有することを特徴とする、木材用抗菌組成物に関する技術である。
一般式（Ｉ）
The present invention relates to an antibacterial composition for wood which can protect wood and wood products from a wide range of fungi including not only filamentous fungi but also discoloring fungi and basidiomycetes with a small amount of use. 2-methyl-4-isothiazolin-3-one and / or a metal complex thereof, 3-iodo-2-propynylbutyl carbamate, and one or more isothiazolone compounds represented by the general formula (I) (provided that 5-chloro- This is a technique relating to an antibacterial composition for wood, which contains one or more compounds selected from 2-methyl-4-isothiazolin-3-one) or benzimidazole compounds as essential components.
Formula (I)
これまで木材用抗菌組成物としてはハロゲン化フェノール化合物や有機スズ化合物が使用されてきたが、これらの化合物は急性および慢性毒性の点や、比較的難分解性であるがゆえの環境汚染の懸念から使用されなくなって久しい。このためより安全性の高い化合物を使用した木材用抗菌組成物の開発が進み、３−ヨード−２−プロピニルブチルカーバメート、４，５−ジクロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オン、２，４，５，６−テトラクロロイソフタロニトリル、２−ベンズイミダゾールカルバミン酸メチル、２−（４−チオシアノメチルチオ）ベンゾチアゾール、Ｎ−ｎ−ブチル−１，２−ベンズイソチアゾリン−３−オン、塩化ジデシルジメチルアンモニウムなどが幅広く使用されている。 Up to now, halogenated phenolic compounds and organotin compounds have been used as antibacterial compositions for wood, but these compounds have acute and chronic toxicity points and concerns about environmental pollution due to their relatively low degradability. It has been a long time since it was no longer used. Therefore, development of antibacterial composition for wood using a safer compound has progressed, and 3-iodo-2-propynylbutyl carbamate, 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one 2,4,5,6-tetrachloroisophthalonitrile, methyl 2-benzimidazolecarbamate, 2- (4-thiocyanomethylthio) benzothiazole, Nn-butyl-1,2-benzisothiazoline-3- ON, didecyldimethylammonium chloride, etc. are widely used.
これら化合物の単独使用では抗菌スペクトルの問題から効力が十分ではなく、使用量増加に伴うコスト増から化合物を複合させた組成物も幅広く使用されている。例えば、特願平２−２９８７３５号には、４，５−ジクロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オンと３−ヨード−２−プロピニルブチルカーバメートを含む殺微生物性組成物（特許文献１）が、特願２０００−６２０７９７号には、３−ヨード−２−プロピニルブチルカーバメートと２−ベンズイミダゾールカルバミン酸メチルを含む抗微生物剤組成物（特許文献２）が、特願平５−３０３２６７号には、５−クロロ−２−メチル−４−イソチアゾリン−３−オンと３−ヨード−２−プロピニルブチルカーバメートを含む工業用防腐防かび剤（特許文献３）が、特願平１−３４３２９０号には、５−クロロ−２−メチル−４−イソチアゾリン−３−オンと４，５−ジクロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オンを含む工業用防菌・防藻組成物（特許文献４）が、特願平２−４６６７２号には、２−ベンズイミダゾールカルバミン酸メチルと５−クロロ−２−メチル−４−イソチアゾリン−３−オンあるいは４，５−ジクロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オンを含むイソチアゾリン化合物を含む工業用防カビ組成物（特許文献５）が提案されている。さらには特願２００２−２５００９６号には、３−ヨード−２−プロピニルブチルカーバメートと４，５−ジクロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オンと２−ベンズイミダゾールカルバミン酸メチルを含む工業用防カビ組成物（特許文献６）が、特願２００２−８４６７３号には４，５−ジクロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オンと２−ベンズイミダゾールカルバミン酸メチルとメチレンビスチオシアネートと３−ヨード−２−プロピニルブチルカーバメートを含む木材防カビ防変色菌組成物（特許文献７）のように３種類以上の化合物を複合させた組成物も提案されている。 The use of these compounds alone is not sufficient due to the problem of the antibacterial spectrum, and a composition in which the compounds are combined is widely used due to the cost increase accompanying the increase in the amount used. For example, Japanese Patent Application No. 2-298735 discloses a microbicidal composition comprising 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one and 3-iodo-2-propynylbutylcarbamate (patent In Japanese Patent Application No. 2000-620797, an antimicrobial composition containing 3-iodo-2-propynylbutyl carbamate and methyl 2-benzimidazole carbamate (Patent Document 2) is disclosed in Japanese Patent Application No. 2000-620797. No. 303267 discloses an industrial antiseptic and fungicidal agent (Patent Document 3) containing 5-chloro-2-methyl-4-isothiazolin-3-one and 3-iodo-2-propynylbutylcarbamate. No. 343290 includes 5-chloro-2-methyl-4-isothiazolin-3-one and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one An antibacterial / algae-proof composition for industrial use (Patent Document 4) is disclosed in Japanese Patent Application No. 2-46672 in which methyl 2-benzimidazolecarbamate and 5-chloro-2-methyl-4-isothiazolin-3-one Alternatively, an industrial antifungal composition (Patent Document 5) containing an isothiazoline compound containing 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one has been proposed. Further, Japanese Patent Application No. 2002-250096 includes 3-iodo-2-propynylbutyl carbamate, 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one and methyl 2-benzimidazole carbamate. An industrial fungicidal composition (Patent Document 6) is disclosed in Japanese Patent Application No. 2002-84673 as 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one, methyl 2-benzimidazolecarbamate and methylene. There has also been proposed a composition in which three or more compounds are combined, such as a wood mildew-proof color-changing fungus composition (Patent Document 7) containing bisthiocyanate and 3-iodo-2-propynylbutylcarbamate.
しかしながら、従来の組成物では木材の表面汚染菌である糸状菌のみに有効である場合がほとんどであり、木材上に生育する微生物は糸状菌だけでなく、変色菌や担子菌のような真菌も認められるため、より幅広い抗菌スペクトルをもつ組成物が望まれている。 However, most of the conventional compositions are effective only against filamentous fungi that are surface contaminants of wood, and the microorganisms that grow on wood are not only filamentous fungi, but also fungi such as discolored and basidiomycetes. As such, compositions with a broader antimicrobial spectrum are desired.
本発明が解決しようとする課題は、木材および木材製品に対して、糸状菌だけでなく変色菌や担子菌を含む幅広い真菌から、少ない使用量で保護することが可能な木材用抗菌組成物を提供することにある。 The problem to be solved by the present invention is to provide an antibacterial composition for wood that can be protected against a wide range of fungi including not only filamentous fungi but also discoloration and basidiomycetes, with respect to wood and wood products. It is to provide.
本発明者は、上記課題を解決するために鋭意種々の研究を行った結果、ａ）５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と、ｂ）３−ヨード−２−プロピニルブチルカーバメートと、ｃ）一般式（Ｉ）
一般式（Ｉ）
で示されるイソチアゾロン化合物またはベンズイミダゾール系化合物から選ばれる一種以上の化合物、を必須成分として含有する組成物によって、木材および木材製品を、糸状菌、変色菌及び担子菌のいずれにも有効であり、これらの幅広い真菌から保護することができることを見出し、本発明を完成させたものである。
すなわち本発明は、
（１）ａ）５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と、ｂ）３−ヨード−２−プロピニルブチルカーバメートと、ｃ）２−ｎ−オクチル−４−イソチアゾリン−３−オン、Ｎ−ｎ−ブチル−１，２−ベンズイソチアゾリン−３−オン、および２−（４−チアゾリル）ベンズイミダゾールから選ばれる一種以上の化合物を必須成分として含有することを特徴とする木材用抗糸状菌用、抗変色菌用、または抗担子菌用組成物に関する。
また本発明は、
（２）５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と３−ヨード−２−プロピニルブチルカーバメートの比率が、重量比で１：１〜１：９の範囲にあり、５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と３−ヨード−２−プロピニルブチルカーバメートの合計と、２−ｎ−オクチル−４−イソチアゾリン−３−オン、Ｎ−ｎ−ブチル−１，２−ベンズイソチアゾリン−３−オン、および２−（４−チアゾリル）ベンズイミダゾールから選ばれる一種以上の化合物の合計の比率が、重量比で５：１〜１：１の範囲にあることを特徴とする発明（１）に記載の木材用抗糸状菌用、抗変色菌用、または抗担子菌用組成物に関する。
The present inventor has conducted various studies in order to solve the above problems, and as a result, a) 5-chloro-2-methyl-4-isothiazolin-3-one and / or a metal complex thereof, and b) 3- Iodo-2-propynylbutylcarbamate, c) general formula (I)
Formula (I)
By using a composition containing as an essential component one or more compounds selected from the isothiazolone compounds or benzimidazole compounds represented by the above, wood and wood products are effective for any of fungi, discoloration fungi and basidiomycetes, The inventors have found that they can be protected from these broad fungi, and have completed the present invention.
That is, the present invention
(1) a) 5-chloro-2-methyl-4-isothiazolin-3-one and / or a metal complex thereof, b) 3-iodo-2-propynylbutylcarbamate, c) 2-n-octyl-4 One or more compounds selected from -isothiazolin-3-one, Nn-butyl-1,2-benzisothiazolin-3-one, and 2- (4-thiazolyl) benzimidazole are contained as essential components The present invention relates to a composition for anti-filamentous fungi for wood, anti-discoloring fungi, or anti-basidiomycetes.
The present invention also provides
(2) The ratio of 5-chloro-2-methyl-4-isothiazolin-3-one and / or its metal complex salt to 3-iodo-2-propynylbutyl carbamate is in the range of 1: 1 to 1: 9 by weight. A total of 5-chloro-2-methyl-4-isothiazolin-3-one and / or its metal complex and 3-iodo-2-propynylbutyl carbamate, and 2-n-octyl-4-isothiazoline-3- The total ratio of one or more compounds selected from ON, Nn-butyl-1,2-benzisothiazolin-3-one, and 2- (4-thiazolyl) benzimidazole is 5: 1 to 1 by weight ratio. The present invention relates to a composition for anti-filamentous fungi for wood, anti-color-changing fungus, or anti-basidiomycete described in the invention (1), characterized in that it is in the range of: 1.
上記組成物を用いることにより、糸状菌だけでなく変色菌や担子菌など幅広い真菌から木材および木材製品を保護することが可能となる。 By using the composition, it is possible to protect wood and wood products from a wide variety of fungi such as discolored bacteria and basidiomycetes as well as filamentous fungi.
本発明の木材用抗菌組成物は、ａ）５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と、ｂ）３−ヨード−２−プロピニルブチルカーバメートと、ｃ）一般式（Ｉ）
一般式（Ｉ）
で示されるイソチアゾロン化合物またはベンズイミダゾール系化合物から選ばれる一種以上の化合物を必須成分として含有するものであり、これらの必須成分を含有する製剤を行うために、溶媒や界面活性剤の他、ｐＨ調整剤、消泡剤、粘度調整剤、防錆剤、金属封鎖剤、他の抗菌組成物等を配合することが可能である。
The antibacterial composition for wood according to the present invention comprises a) 5-chloro-2-methyl-4-isothiazolin-3-one and / or a metal complex thereof, b) 3-iodo-2-propynylbutylcarbamate, and c). Formula (I)
Formula (I)
It contains one or more compounds selected from isothiazolone compounds or benzimidazole compounds represented by the above as essential components, and in addition to solvents and surfactants, pH adjustment is performed in order to carry out preparations containing these essential components. Agents, antifoaming agents, viscosity modifiers, rust inhibitors, metal sequestering agents, other antibacterial compositions, and the like can be blended.
本発明の抗菌組成物の対象微生物は、糸状菌、変色菌、担子菌など広範囲にわたり、本発明の木材用抗菌組成物はかかる広範囲の微生物に対して優れた効果を発揮する。 The target microorganisms of the antibacterial composition of the present invention are wide-ranging such as filamentous fungi, discoloration bacteria, basidiomycetes, and the antibacterial composition for wood of the present invention exhibits excellent effects against such a wide range of microorganisms.
本発明で使用する５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩（以下ＣＭＩＴと省略する）は公知の技術によって製造することができるが、例えば、「ＫＡＴＨＯＮ（登録商標） ＬＸ ＳＦ２５」（ＣＭＩＴを１８重量％と２−メチル−４−イソチアゾリン−３−オンを７重量％含有）としてＲＯＨＭ ＡＮＤ ＨＡＡＳ社から市販されているものや、「ＺＯＮＥＮ（登録商標） ＦＰ」（ＣＭＩＴを１１重量％と２−メチル−４−イソチアゾリン−３−オンを１重量％含有）としてケミクレア社から市販されているものが利用可能であり、ＣＭＩＴの金属錯塩としてはマグネシウム錯塩やナトリウム錯塩を利用することができ、例えば、「ＫＡＴＨＯＮ ＷＴ」（ＣＭＩＴのマグネシウム錯塩を含有）や「ＫＡＴＨＯＮ ＬＸ１４００」（ＣＭＩＴのナトリウム錯塩を含有）としてＲＯＨＭ ＡＮＤ ＨＡＡＳ社から市販されているものが利用可能である。 5-Chloro-2-methyl-4-isothiazolin-3-one and / or its metal complex salt (hereinafter abbreviated as CMIT) used in the present invention can be produced by a known technique. For example, “KATHON ( (Registered trademark) LX SF25 "(containing 18% by weight of CMIT and 7% by weight of 2-methyl-4-isothiazolin-3-one), commercially available from ROHM AND HAAS, or" ZONEN (registered trademark) FP "(Combined with 11% by weight of CMIT and 1% by weight of 2-methyl-4-isothiazolin-3-one) is commercially available from Chemicrea Co., and as metal complex salts of CMIT, magnesium complex salts and sodium are available. Complex salts can be used, for example, “KATHON WT” (contains magnesium complex salt of CMIT And "KATHON LX1400" (containing sodium complex salt of CMIT) which is commercially available from ROHM the AND HAAS Company as are available.
本発明で使用する３−ヨード−２−プロピニルブチルカーバメート（以下ＩＰＢＣと省略する）は公知の技術によって製造することができるが、例えば、「ＯＭＡＣＩＤＥ（登録商標） ＩＰＢＣ」としてＡＲＣＨ ＣＨＥＭＩＣＡＬＳ社から市販されているものが利用可能である。 The 3-iodo-2-propynyl butyl carbamate (hereinafter abbreviated as IPBC) used in the present invention can be produced by a known technique. For example, it is commercially available from ARCH CHEMICALS as “OMACIDE (registered trademark) IPBC”. Is available.
本発明で使用する一般式（Ｉ）
一般式（Ｉ）
で示されるイソチアゾロン化合物には、４，５−ジクロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オン（以下ＤＣＯＩＴと省略する）、２−ｎ−オクチル−４−イソチアゾリン−３−オン（以下ＯＩＴと省略する）、Ｎ−ｎ−ブチル−１，２−ベンズイソチアゾリン−３−オン（以下ＢＢＩＴと省略する）、１，２−ベンズイソチアゾリン−３−オン、Ｎ−メチル−１，２−ベンズイソチアゾリン−３−オン、Ｎ−エチル−１，２−ベンズイソチアゾリン−３−オン、２−エチル−４−イソチアゾリン−３−オン、２−ｎ−ブチル−４−イソチアゾリン−３−オン、５−クロロ−２−ｎ−オクチル−４−イソチアゾリン−３−オン等が挙げられる。これらは公知の技術によって製造することができるが、例えばＤＣＯＩＴであれば、「ＫＡＴＨＯＮ ２８７ＰＸＥ」（ＤＣＯＩＴを２５重量％含有）としてＲＯＨＭ ＡＮＤ ＨＡＡＳ社から市販されているものが利用可能であり、ＯＩＴであれば、「ＺＯＮＥＮ Ｏ／１００」としてケミクレア社から市販されているものが利用可能であり、ＢＢＩＴであれば、「ＤＥＮＳＩＬ（登録商標） ＤＮ」としてＡＲＣＨ ＣＨＥＭＩＣＡＬＳ社から市販されているものが利用可能である。また、２−ベンズイミダゾールカルバミン酸メチル（以下ＢＣＭと省略する）は、例えば、「ＰＲＥＶＥＮＴＯＬ（登録商標）ＢＣＭ」としてＬＡＮＸＥＳＳ社から市販されているものが利用可能であり、２−（４−チアゾリル）ベンズイミダゾール（以下ＴＢＺと省略する）は、例えば、「シントールＭ−１００」として住化エンビロサイエンス社から市販されているものが利用可能である。
General formula (I) used in the present invention
Formula (I)
Examples of the isothiazolone compound include 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (hereinafter abbreviated as DCOIT), 2-n-octyl-4-isothiazoline-3-one (hereinafter referred to as DCOIT). OIT), Nn-butyl-1,2-benzisothiazolin-3-one (hereinafter abbreviated as BBIT), 1,2-benzisothiazolin-3-one, N-methyl-1,2-benz Isothiazolin-3-one, N-ethyl-1,2-benzisothiazolin-3-one, 2-ethyl-4-isothiazolin-3-one, 2-n-butyl-4-isothiazolin-3-one, 5-chloro 2-n-octyl-4-isothiazolin-3-one and the like. These can be manufactured by a known technique. For example, in the case of DCOIT, “KATHON 287PXE” (containing 25% by weight of DCOIT) is commercially available from ROHM AND HAAS. If available, a product marketed by Chemiclear as “ZONEN O / 100” can be used, and if it is BBIT, a product marketed by ARCH CHEMICALS as “DENSIL (registered trademark) DN” can be used. It is. As methyl 2-benzimidazolecarbamate (hereinafter abbreviated as BCM), for example, commercially available from LANXESS as “PREVENTOL (registered trademark) BCM” can be used. 2- (4-thiazolyl) As benzimidazole (hereinafter abbreviated as TBZ), for example, “Sintol M-100” commercially available from Sumika Enviro Science can be used.
５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と３−ヨード−２−プロピニルブチルカーバメートの比率については、重量比で１：１０〜１０：１の範囲、好ましくは重量比で１：５〜５：１の範囲で使用することができる。５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と３−ヨード−２−プロピニルブチルカーバメートの合計と、一般式（Ｉ）
一般式（Ｉ）
で示されるイソチアゾロン化合物（ただし、５−クロロ−２−メチル−４−イソチアゾリン−３−オンを除く）またはベンズイミダゾール系化合物から選ばれる一種以上の化合物の合計の比率については、重量比で１：１０〜１０：１の範囲、好ましくは１：５〜５：１の範囲で使用することができる。
The ratio of 5-chloro-2-methyl-4-isothiazolin-3-one and / or its metal complex to 3-iodo-2-propynylbutyl carbamate is preferably in the range of 1:10 to 10: 1 by weight. Can be used in a weight ratio of 1: 5 to 5: 1. The sum of 5-chloro-2-methyl-4-isothiazolin-3-one and / or its metal complex and 3-iodo-2-propynylbutylcarbamate, and a compound of the general formula (I)
Formula (I)
The total ratio of one or more compounds selected from the isothiazolone compounds (excluding 5-chloro-2-methyl-4-isothiazolin-3-one) or a benzimidazole compound represented by the formula: It can be used in the range of 10 to 10: 1, preferably in the range of 1: 5 to 5: 1.
本発明の木材用抗菌組成物の製剤を行う上で配合可能な溶媒としては、水の他、エタノールやイソプロパノール等の一価アルコール類、エチレングリコール、ジエチレングリコール、ポリエチレングリコール、プロピレングリコール、ジプロピレングリコール等のグリコール系溶剤およびその誘導体、グリセリン、ジグリセリン等のグリセリン系溶剤およびその誘導体、Ｎ−メチルピロリドンやγ−ブチロラクトンなどの環状有機溶媒、フタル酸エステルやアジピン酸エステルやセバシン酸エステルなどのエステル系溶媒、メチルナフタレンやフェニルキシリルエタンやアルキルベンゼンなどの芳香族系溶媒、ノルマルパラフィンやイソパラフィンなどの脂肪族炭化水素溶媒、菜種油や綿実油や大豆油やヒマシ油やなどが使用することができる。これら溶媒は、単独で使用してもよく、２種類以上を併用することも可能である。 Solvents that can be blended in the preparation of the antibacterial composition for wood of the present invention include water, monohydric alcohols such as ethanol and isopropanol, ethylene glycol, diethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol and the like Glycol solvents and derivatives thereof, glycerol solvents and derivatives thereof such as glycerol and diglycerol, cyclic organic solvents such as N-methylpyrrolidone and γ-butyrolactone, ester systems such as phthalate ester, adipic acid ester and sebacic acid ester Solvents, aromatic solvents such as methylnaphthalene, phenylxylylethane and alkylbenzene, aliphatic hydrocarbon solvents such as normal paraffin and isoparaffin, rapeseed oil, cottonseed oil, soybean oil and castor oil can be used. . These solvents may be used alone or in combination of two or more.
界面活性剤としては、例えばポリオキシアルキレンアルキルエーテル、ポリオキシアルキレンアリルフェニルエーテル、グリセリン脂肪酸エステル、ソルビタン脂肪酸エステル、ポリオキシアルキレンソルビタン脂肪酸エステル、ポリオキシアルキレン硬化ヒマシ油等のノニオン界面活性剤や、アルキルサルフェート塩、アルキルエーテルサルフェート塩、アルキルスルホサクシネート塩、アルキルスルホネート塩、アルキルアリルスルホネート塩、脂肪酸アミドスルホネート塩、アルキルホスフェート塩、アルキルエーテルホスフェート塩、ナフタレンスルホン酸ホルムアルデヒド縮合物塩等のアニオン界面活性剤や、アルキルアミン塩、アルキルアンモニウム塩等のカチオン界面活性剤や、グリシン型、ベタイン型、イミダゾリン型等の両性界面活性剤を使用することができる。これら界面活性剤は単独で使用してもよく、２種類以上を組み合わせて使用することも可能である。 Examples of the surfactant include nonionic surfactants such as polyoxyalkylene alkyl ether, polyoxyalkylene allyl phenyl ether, glycerin fatty acid ester, sorbitan fatty acid ester, polyoxyalkylene sorbitan fatty acid ester, polyoxyalkylene hydrogenated castor oil, and alkyl Anionic surfactants such as sulfate salts, alkyl ether sulfate salts, alkyl sulfosuccinate salts, alkyl sulfonate salts, alkyl allyl sulfonate salts, fatty acid amide sulfonate salts, alkyl phosphate salts, alkyl ether phosphate salts, naphthalene sulfonic acid formaldehyde condensate salts And cationic surfactants such as alkylamine salts and alkylammonium salts, glycine type, betaine type, imidazoline type, etc. It can be used sex surfactant. These surfactants may be used alone or in combination of two or more.
ｐＨ調整剤としては、コハク酸やクエン酸、酒石酸等の有機酸やそれらの塩、リン酸やポリリン酸、ホウ酸等の無機酸やそれらの塩等が使用可能であり、消泡剤としては、鉱油系、シリコーン系、ポリエーテル系等の消泡剤が使用可能であり、防錆剤としては、ベンゾトリアゾール、ジシクロヘキシルアンモニウム亜硝酸塩、リン酸水素ナトリウム、リン酸水素アンモニウム等が使用可能であり、粘度調整剤としてはキサンタンガム、カルボキシメチルセルロース、ヒドロキシエチルセルロース、アラビアガム等が使用可能であり、金属封鎖剤としては、エチレンジアミン四酢酸および／またはその塩、ニトリロ三酢酸および／またはその塩、ジエチレントリアミン五酢酸および／またはその塩、ヒドロキシエチルエチレンジアミン三酢酸および／またはその塩、トリエチレンテトラミン六酢酸および／またはその塩、１，３−プロパンジアミン四酢酸および／またはその塩、１，３−ジアミノ−２−ヒドロキシプロパン四酢酸および／またはその塩、１−ヒドロキシエチリデン−１，１−ジホスホン酸および／またはその塩、ヒドロキシエチルイミノ二酢酸および／またはその塩、ジヒドロキシエチルグリシンおよび／またはその塩、グリコールエーテルジアミン四酢酸および／またはその塩、ジカルボキシメチルグルタミン酸および／またはその塩、ニトリロトリスメチレンリン酸および／またはその塩等が使用可能であり、他の抗菌組成物としては、メチレンビスチオシアネート、２−（４−チオシアノメチルチオ）ベンゾチアゾール、２−ブロモーニトロプロパン−１，３−ジオール、２，２−ジブロモ−２−ニトロエタノール、２，３，３−トリヨードアリルアルコール、ジヨードメチル−ｐ−トリルスルホン、２，３，５，６−テトラクロロ−４−（メチルスルホニル）ピリジン、２，４，５，６−テトラクロロイソフタロニトリル、亜鉛ピリチオン、ｏ−フェニルフェノール、イソプロピルメチルフェノール、パラクロロメタキシレノール、ｐ−オキシ安息香酸アルキルエステル等が使用可能である。 As pH adjusters, organic acids such as succinic acid, citric acid, tartaric acid and their salts, inorganic acids such as phosphoric acid, polyphosphoric acid, boric acid and their salts can be used, and as antifoaming agents Antifoaming agents such as mineral oils, silicones and polyethers can be used, and as rust inhibitors, benzotriazole, dicyclohexylammonium nitrite, sodium hydrogenphosphate, ammonium hydrogenphosphate, etc. can be used Xanthan gum, carboxymethylcellulose, hydroxyethylcellulose, gum arabic, etc. can be used as the viscosity modifier, and as the sequestering agent, ethylenediaminetetraacetic acid and / or its salt, nitrilotriacetic acid and / or its salt, diethylenetriaminepentaacetic acid And / or its salt, hydroxyethylethylenediaminetriacetic acid And / or a salt thereof, triethylenetetramine hexaacetic acid and / or a salt thereof, 1,3-propanediaminetetraacetic acid and / or a salt thereof, 1,3-diamino-2-hydroxypropanetetraacetic acid and / or a salt thereof, 1 -Hydroxyethylidene-1,1-diphosphonic acid and / or salt thereof, hydroxyethyliminodiacetic acid and / or salt thereof, dihydroxyethylglycine and / or salt thereof, glycol etherdiaminetetraacetic acid and / or salt thereof, dicarboxymethyl Glutamic acid and / or a salt thereof, nitrilotrismethylene phosphoric acid and / or a salt thereof can be used, and other antibacterial compositions include methylene bis thiocyanate, 2- (4-thiocyanomethylthio) benzothiazole, 2- Bromo-nitropropane-1,3 Diol, 2,2-dibromo-2-nitroethanol, 2,3,3-triiodoallyl alcohol, diiodomethyl-p-tolylsulfone, 2,3,5,6-tetrachloro-4- (methylsulfonyl) pyridine, 2,4,5,6-tetrachloroisophthalonitrile, zinc pyrithione, o-phenylphenol, isopropylmethylphenol, parachlorometaxylenol, p-oxybenzoic acid alkyl ester, and the like can be used.
本発明の木材用抗菌組成物の剤型は、とくに限定されず、乳剤や可溶化剤、フロアブル製剤、サスポエマルション製剤、水和剤などにより提供することが可能であり、またフロアブル製剤とサスポエマルション製剤の組合せ、可溶化剤とフロアブル製剤の組合せのように、二種類以上の剤型を組み合わせることも可能である。製材業者などでの実使用場面を考慮すると、水に希釈可能な剤型とするのが好ましい。 The dosage form of the antibacterial composition for wood according to the present invention is not particularly limited, and can be provided by an emulsion, a solubilizer, a flowable preparation, a suspoemulsion preparation, a wettable powder, and the like. It is also possible to combine two or more types of dosage forms, such as a combination of a spoemulsion formulation and a combination of a solubilizer and a flowable formulation. Considering the actual use situation at a lumbering company, it is preferable to make the dosage form dilutable in water.
以下、実施例および比較例により本発明を具体的に説明するが、本発明はこれらの実施例によって限定されるものではない。なお特に断りがない限り、「％」は「重量％」を表す。
（木材用抗菌組成物実施例）
EXAMPLES Hereinafter, although an Example and a comparative example demonstrate this invention concretely, this invention is not limited by these Examples. Unless otherwise specified, “%” represents “% by weight”.
(Antimicrobial composition example for wood)
ＩＰＢＣ ２部、日石ハイゾールＳＡＳ２９６ １８部、ニューカルゲンＣＰ−１２０ ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＴＢＺ ２部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部とイオン交換水 １３．８部を混合して実施例１とした（ＩＰＢＣ ２％、ＴＢＺ ２％、ＣＭＩＴ ２％）。 2 parts of IPBC, 18 parts of Nisseki Hyzol SAS296, 2 parts of Neukalgen CP-120, 0.2 parts of sodium dioctylsulfosuccinate are mixed and dissolved in 18 parts of ion-exchanged water and emulsified, and 2 parts of TBZ. A mixture of 1 part of New Calgen CP-120 and 7 parts of ion exchanged water and pulverized with a bead mill for 20 minutes was mixed with 25 parts of 1% aqueous solution of xanthan gum, 11 parts of KATON LX SF25 and 13.8 parts of ion exchanged water. The mixture was mixed to obtain Example 1 (IPBC 2%, TBZ 2%, CMIT 2%).
ＩＰＢＣ ２部、ＤＥＮＳＩＬ ＤＮ ２．１部、ジエチレングリコールモノ−ｎ−ブチルエーテル ６９．９部とエマルゲンＬＳ１１４ １５部、ＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部を混合溶解して実施例２とした（ＩＰＢＣ ２％、ＢＢＩＴ ２％、ＣＭＩＴ ２％）。 2 parts of IPBC, 2.1 parts of DENSIL DN, 69.9 parts of diethylene glycol mono-n-butyl ether, 15 parts of Emulgen LS114, and 11 parts of KATHON LX SF25 were mixed and dissolved in Example 2 (IPBC 2%, BBIT 2% , CMIT 2%).
ＩＰＢＣ ２部、ＺＯＮＥＮ Ｏ／１００ ２部、ジエチレングリコールモノ−ｎ−ブチルエーテル ７０部とエマルゲンＬＳ１１４ １５部、ＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部を混合溶解して実施例３とした（ＩＰＢＣ ２％、ＯＩＴ ２％、ＣＭＩＴ ２％）。 IPBC 2 parts, ZONEN O / 100 2 parts, diethylene glycol mono-n-butyl ether 70 parts, Emulgen LS114 15 parts, and KATON LX SF25 11 parts were mixed and dissolved in Example 3 (IPBC 2%, OIT 2%, CMIT 2%).
ＩＰＢＣ ２部、ＫＡＴＨＯＮ ２８７ＰＸＥ ８部、日石ハイゾールＳＡＳ２９６ １０部、ニューカルゲンＣＰ−１２０ ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＴＢＺ ２部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部とイオン交換水 １３．８部を混合して実施例４とした（ＩＰＢＣ ２％、ＤＣＯＩＴ ２％、ＴＢＺ ２％、ＣＭＩＴ ２％）。 2 parts of IPBC, 8 parts of KATON 287PXE, 10 parts of Nisseki Hyzol SAS296, 2 parts of New Calgen CP-120, 0.2 part of sodium dioctylsulfosuccinate are mixed and added dropwise to emulsify 18 parts of ion-exchanged water. 2 parts of TBZ, 1 part of Neukalgen CP-120 and 7 parts of ion-exchanged water were mixed together after being pulverized in a bead mill for 20 minutes, 25 parts of 1% aqueous solution of xanthan gum, 11 parts of KATHON LX SF25 and ion-exchanged water. 13.8 parts were mixed to make Example 4 (IPBC 2%, DCOIT 2%, TBZ 2%, CMIT 2%).
ＩＰＢＣ ２部、ＺＯＮＥＮ Ｏ／１００ ２部、日石ハイゾールＳＡＳ２９６ １０部、ニューカルゲンＣＰ−１２０ ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＴＢＺ ２部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部とイオン交換水 １９．８部を混合して実施例５とした（ＩＰＢＣ ２％、ＯＩＴ ２％、ＴＢＺ ２％、ＣＭＩＴ ２％）。 IPBC 2 parts, ZONEN O / 100 2 parts, Nisseki Hyzol SAS296 10 parts, New Calgen CP-120 2 parts, dioctyl sulfosuccinate sodium 0.2 parts are mixed and dissolved in 18 parts of ion-exchanged water. Emulsified, mixed with 2 parts TBZ, 1 part Neukalgen CP-120, 7 parts ion-exchanged water and pulverized with a bead mill for 20 minutes, mixed with 25 parts 1% aqueous xanthan gum, 11 parts KATHON LX SF25 and ions 19.8 parts of exchange water was mixed to obtain Example 5 (IPBC 2%, OIT 2%, TBZ 2%, CMIT 2%).
ＩＰＢＣ ２部、ＤＥＮＳＩＬ ＤＮ ２．１部、日石ハイゾールＳＡＳ２９６ １０部、ニューカルゲンＣＰ−１２０ ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＢＣＭ ２部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部とイオン交換水 １９．７部を混合 して実施例６とした（ＩＰＢＣ ２％、ＢＢＩＴ ２％、ＢＣＭ ２%、ＣＭＩＴ ２％）。 IPBC 2 parts, DENSIL DN 2.1 parts, Nisseki Hyzol SAS296 10 parts, Newkalgen CP-120 2 parts, sodium dioctyl sulfosuccinate 0.2 part mixed and dissolved in 18 parts of ion-exchanged water. Emulsified, mixed with 2 parts BCM, 1 part Newkargen CP-120, 7 parts ion-exchanged water and pulverized with a bead mill for 20 minutes, mixed with 25 parts 1% aqueous xanthan gum, 11 parts KATHON LX SF25 and ions 19.7 parts of exchange water was mixed to obtain Example 6 (IPBC 2%, BBIT 2%, BCM 2%, CMIT 2%).
〔比較例１〕
ＩＰＢＣ ３部、ＫＡＴＨＯＮ ２８７ＰＸＥ １２部、ジエチレングリコールモノ−ｎ−ブチルエーテル ６５部とエマルゲンＬＳ１１４ ２０部を混合溶解して比較例１とした（ＩＰＢＣ ３％、ＤＣＯＩＴ ３％）。
[Comparative Example 1]
3 parts of IPBC, 12 parts of KATHON 287PXE, 65 parts of diethylene glycol mono-n-butyl ether and 20 parts of Emulgen LS114 were mixed and dissolved in Comparative Example 1 (IPBC 3%, DCOIT 3%).
〔比較例２〕
ＩＰＢＣ ３部、ジエチレングリコールモノ−ｎ−ブチルエーテル ６５．５部とエマルゲンＬＳ１１４ １５部、ＫＡＴＨＯＮ ＬＸ ＳＦ２５ １６．５部を混合溶解して比較例２とした（ＩＰＢＣ ３％、ＣＭＩＴ ３％）。
[Comparative Example 2]
3 parts of IPBC, 65.5 parts of diethylene glycol mono-n-butyl ether, 15 parts of Emulgen LS114, and 16.5 parts of KATHON LX SF25 were mixed and dissolved in Comparative Example 2 (IPBC 3%, CMIT 3%).
〔比較例３〕
ＫＡＴＨＯＮ ２８７ＰＸＥ １２部、ジエチレングリコールモノ−ｎ−ブチルエーテル ５６．５部とエマルゲンＬＳ１１４ １５部、ＫＡＴＨＯＮ ＬＸ ＳＦ２５ １６．５部を混合溶解して比較例３とした（ＤＣＯＩＴ ３％、ＣＭＩＴ ３％）。
[Comparative Example 3]
12 parts of KATHON 287PXE, 56.5 parts of diethylene glycol mono-n-butyl ether, 15 parts of Emulgen LS114, and 16.5 parts of KATHON LX SF25 were mixed and dissolved in Comparative Example 3 (DCOIT 3%, CMIT 3%).
〔比較例４〕
ＩＰＢＣ ３部、日石ハイゾールＳＡＳ２９６ １８部、ニューカルゲンＣＰ−１２０ ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＢＣＭ ３部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とイオン交換水 ２２．８部を混合して比較例４とした（ＩＰＢＣ ３％、ＢＣＭ ３％）。
[Comparative Example 4]
3 parts of IPBC, 18 parts of Nisseki Hyzol SAS296, 2 parts of Neukalgen CP-120, 0.2 part of sodium dioctylsulfosuccinate were mixed and dissolved in 18 parts of ion-exchanged water and emulsified, and 3 parts of BCM, Comparative Example 4 in which 1 part of New Calgen CP-120 and 7 parts of ion exchange water were mixed and pulverized with a bead mill for 20 minutes were mixed, and 25 parts of a 1% aqueous solution of xanthan gum and 22.8 parts of ion exchange water were mixed. (IPBC 3%, BCM 3%).
〔比較例５〕
ＫＡＴＨＯＮ ２８７ＰＸＥ １２部、日石ハイゾールＳＡＳ２９６ １０部、ニューカルゲンＣＰ−１２０ ２．５部、ジオクチルスルホコハク酸ナトリウム ０．３部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＢＣＭ ３部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とイオン交換水 ２１．２部を混合して比較例５とした（ＤＣＯＩＴ ３％、ＢＣＭ ３％）。
[Comparative Example 5]
12 parts of KATON 287PXE, 10 parts of Nisseki Hyzol SAS296, 2.5 parts of New Calgen CP-120, 0.3 parts of sodium dioctylsulfosuccinate are mixed and dissolved in 18 parts of ion-exchanged water, and emulsified to obtain BCM. Mix 3 parts, 1 part of Neukalgen CP-120, 7 parts of ion exchange water and pulverize with a bead mill for 20 minutes. Mix 25 parts of 1% aqueous solution of xanthan gum and 21.2 parts of ion exchange water. It was set as Comparative Example 5 (DCOIT 3%, BCM 3%).
〔比較例６〕
ＢＣＭ ３部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものと、キサンタンガムの１％水溶液 ３０部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ １６．５部とイオン交換水 ４２．５部を混合して比較例６とした（ＢＣＭ ３％、ＣＭＩＴ ３％）。
[Comparative Example 6]
3 parts of BCM, 1 part of New Calgen CP-120, 7 parts of ion-exchanged water and pulverized with a bead mill for 20 minutes, 30 parts of 1% aqueous solution of xanthan gum, 16.5 parts of KATHON LX SF25, and ion-exchanged water 42 .5 parts were mixed to make Comparative Example 6 (BCM 3%, CMIT 3%).
〔比較例７〕
ＩＰＢＣ ３部、ＺＯＮＥＮ Ｏ／１００ ３部、日石ハイゾールＳＡＳ２９６ １５部、ニューカルゲンＣＰ−１２０ ３部、ジオクチルスルホコハク酸ナトリウム ０．３部を混合溶解したものにイオン交換水 ２７部を滴下混合して乳化させ、キサンタンガムの１％水溶液 ２５部とイオン交換水 ２３．７部を混合して比較例７とした（ＩＰＢＣ ３％、ＯＩＴ ３％）。
[Comparative Example 7]
IPBC 3 parts, ZONEN O / 100 3 parts, Nisseki Hyzol SAS296 15 parts, New Calgen CP-120 3 parts, and sodium dioctyl sulfosuccinate 0.3 part were mixed and dropped into ion-exchanged water 27 parts. The mixture was emulsified and mixed with 25 parts of a 1% aqueous solution of xanthan gum and 23.7 parts of ion-exchanged water to obtain Comparative Example 7 (IPBC 3%, OIT 3%).
〔比較例８〕
ＩＰＢＣ ６部、ジエチレングリコールモノ−ｎ−ブチルエーテル ７４部とエマルゲンＬＳ１１４ ２０部を混合溶解して比較例７とした（ＩＰＢＣ ６％）。
[Comparative Example 8]
6 parts of IPBC, 74 parts of diethylene glycol mono-n-butyl ether and 20 parts of Emulgen LS114 were mixed and dissolved to obtain Comparative Example 7 (IPBC 6%).
〔比較例９〕
ＫＡＴＨＯＮ ２８７ＰＸＥ ２４部、ジエチレングリコールモノ−ｎ−ブチルエーテル ５６部とエマルゲンＬＳ１１４ ２０部を混合溶解して比較例８とした（ＤＣＯＩＴ ６％）。
[Comparative Example 9]
A comparative example 8 was prepared by mixing and dissolving 24 parts of KATHON 287PXE, 56 parts of diethylene glycol mono-n-butyl ether and 20 parts of Emulgen LS114 (DCOIT 6%).
〔比較例１０〕
ジエチレングリコールモノ−ｎ−ブチルエーテル ６２部とエマルゲンＬＳ１１４ ５部、ＫＡＴＨＯＮ ＬＸ ＳＦ２５ ３３部を混合溶解して比較例９とした（ＣＭＩＴ ６％）。
[Comparative Example 10]
62 parts of diethylene glycol mono-n-butyl ether, 5 parts of Emulgen LS114, and 33 parts of KATHON LX SF25 were mixed and dissolved in Comparative Example 9 (CMIT 6%).
〔比較例１１〕
ＢＣＭ ６部、ニューカルゲンＣＰ−１２０ ２部、イオン交換水 １４部を混合してビーズミルで２０分間粉砕したものに、キサンタンガムの１％水溶液 ２５部とイオン交換水 ５３部を混合して比較例１０とした（ＢＣＭ ６％）。
[Comparative Example 11]
Comparative Example 10 by mixing 25 parts of 1% aqueous solution of xanthan gum and 53 parts of ion-exchanged water with 6 parts of BCM, 2 parts of Neukalgen CP-120 and 14 parts of ion-exchanged water and pulverized with a bead mill for 20 minutes. (BCM 6%).
〔比較例１２〕
ＴＢＺ ６部、ニューカルゲンＣＰ−１２０ ２部、イオン交換水 １４部を混合してビーズミルで２０分間粉砕したものに、キサンタンガムの１％水溶液 ２５部とイオン交換水 ５３部を混合して比較例１１とした（ＴＢＺ ６％）。
[Comparative Example 12]
Comparative Example 11 was prepared by mixing 6 parts of TBZ, 2 parts of Neukalgen CP-120, and 14 parts of ion-exchanged water and pulverizing with a bead mill for 20 minutes, mixing 25 parts of a 1% aqueous solution of xanthan gum and 53 parts of ion-exchanged water. (TBZ 6%).
〔比較例１３〕
ＺＯＮＥＮ Ｏ／１００ ６部、ジエチレングリコールモノ−ｎ−ブチルエーテル ７４部とエマルゲンＬＳ１１４ ２０部を混合溶解して比較例１３とした（ＯＩＴ ６％）。
[Comparative Example 13]
6 parts of ZONEN O / 100, 74 parts of diethylene glycol mono-n-butyl ether and 20 parts of Emulgen LS114 were mixed and dissolved in Comparative Example 13 (OIT 6%).
〔参考例１〕
ＩＰＢＣ ２部、ＫＡＴＨＯＮ ２８７ＰＸＥ ８部、ジエチレングリコールモノ−ｎ−ブチルエーテル ６４部とエマルゲンＬＳ１１４（花王社、ポリオキシエチレンポリオキシプロピレンアルキルエーテル） １５部、ＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部を混合溶解して参考例１とした（ＩＰＢＣ ２％、ＤＣＯＩＴ ２％、ＣＭＩＴ ２％）。
[Reference Example 1]
2 parts IPBC, 8 parts KATHON 287PXE, 64 parts diethylene glycol mono-n-butyl ether, 15 parts Emulgen LS114 (Kao Corporation, polyoxyethylene polyoxypropylene alkyl ether) and 11 parts KATHON LX SF25 (IPBC 2%, DCOIT 2%, CMIT 2%).
〔参考例２〕
ＩＰＢＣ ２部、日石ハイゾール（登録商標）ＳＡＳ２９６（ＪＸ日鉱日石エネルギー社） １８部、ニューカルゲンＣＰ−１２０（竹本油脂社、ポリオキシアルキレンアリルフェニルエーテル） ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＢＣＭ ２部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部とイオン交換水 １３．８部を混合して参考例２とした（ＩＰＢＣ ２％、ＢＣＭ ２％、ＣＭＩＴ ２％）。
[Reference Example 2]
IPBC 2 parts, Nisseki Hyzol (registered trademark) SAS296 (JX Nippon Oil & Energy Corporation) 18 parts, New Calgen CP-120 (Takemoto Yushi Co., Ltd., polyoxyalkylene allyl phenyl ether) 2 parts, sodium dioctylsulfosuccinate 0.2 18 parts of ion-exchanged water is added dropwise to the mixture and emulsified, and emulsified. Then, 2 parts of BCM, 1 part of Newkargen CP-120 and 7 parts of ion-exchanged water are mixed and pulverized in a bead mill for 20 minutes. Then, 25 parts of a 1% aqueous solution of xanthan gum, 11 parts of KATHON LX SF25 and 13.8 parts of ion-exchanged water were mixed to obtain Reference Example 2 (IPBC 2%, BCM 2%, CMIT 2%).
〔参考例３〕
ＩＰＢＣ ３部、日石ハイゾールＳＡＳ２９６ １８部、ニューカルゲンＣＰ−１２０ ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＢＣＭ ２部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ ５．５部とイオン交換水 １８．３部を混合して参考例３とした（ＩＰＢＣ ３％、ＢＣＭ ２％、ＣＭＩＴ １％）。
[Reference Example 3]
IPBC 3 parts, Nisseki Hyzol SAS296 18 parts, Neukalgen CP-120 2 parts, Dioctyl sulfosuccinate 0.2 part mixed and dissolved 18 parts of ion-exchanged water was mixed and emulsified, BCM 2 parts, A mixture of 1 part of New Calgen CP-120 and 7 parts of ion-exchanged water and pulverized with a bead mill for 20 minutes, 25 parts of 1% aqueous solution of xanthan gum, 5.5 parts of KATON LX SF25 and 18.3 of ion-exchanged water Parts were mixed to obtain Reference Example 3 (IPBC 3%, BCM 2%, CMIT 1%).
〔参考例４〕
ＩＰＢＣ ３部、ＫＡＴＨＯＮ ２８７ＰＸＥ ４部、ジエチレングリコールモノ−ｎ−ブチルエーテル ５７部とエマルゲンＬＳ１１４ １５部、ＫＡＴＨＯＮ ＷＴ ２１部を混合溶解して参考例４とした（ＩＰＢＣ ３％、ＤＣＯＩＴ １％、ＣＭＩＴ ２％）。
[Reference Example 4]
3 parts of IPBC, 4 parts of KATHON 287PXE, 57 parts of diethylene glycol mono-n-butyl ether, 15 parts of Emulgen LS114, and 21 parts of KATHON WT were mixed and dissolved in Reference Example 4 (IPBC 3%, DCOIT 1%, CMIT 2%) .
〔参考例５〕
ＩＰＢＣ ３．６部、ＫＡＴＨＯＮ ２８７ＰＸＥ ８部、ジエチレングリコールモノ−ｎ−ブチルエーテル ７１．２部とエマルゲンＬＳ１１４ １５部、ＫＡＴＨＯＮ ＬＸ ＳＦ２５ ２．２部を混合溶解して参考例５とした（ＩＰＢＣ ３．６％、ＤＣＯＩＴ ２％、ＣＭＩＴ ０．４％）。
[Reference Example 5]
3.6 parts of IPBC, 8 parts of KATHON 287PXE, 71.2 parts of diethylene glycol mono-n-butyl ether, 15 parts of Emulgen LS114, and 2.2 parts of KATHON LX SF25 were mixed and dissolved in Reference Example 5 (IPBC 3.6% , DCOIT 2%, CMIT 0.4%).
〔参考例６〕
ＩＰＢＣ ２部、ＫＡＴＨＯＮ ２８７ＰＸＥ ８部、日石ハイゾールＳＡＳ２９６ １０部、ニューカルゲンＣＰ−１２０ ２部、ジオクチルスルホコハク酸ナトリウム ０．２部を混合溶解したものにイオン交換水 １８部を滴下混合して乳化させ、ＢＣＭ ２部、ニューカルゲンＣＰ−１２０ １部、イオン交換水 ７部を混合してビーズミルで２０分間粉砕したものを混合し、キサンタンガムの１％水溶液 ２５部とＫＡＴＨＯＮ ＬＸ ＳＦ２５ １１部とイオン交換水 １３．８部を混合して参考例６とした（ＩＰＢＣ ２％、ＤＣＯＩＴ ２％、ＢＣＭ ２％、ＣＭＩＴ ２％）。
[Reference Example 6]
2 parts of IPBC, 8 parts of KATON 287PXE, 10 parts of Nisseki Hyzol SAS296, 2 parts of New Calgen CP-120, 0.2 part of sodium dioctylsulfosuccinate are mixed and added dropwise to emulsify 18 parts of ion-exchanged water. 2 parts of BCM, 1 part of Neukalgen CP-120 and 7 parts of ion-exchanged water, mixed with 20 minutes of pulverization with a bead mill, mixed with 25 parts of 1% aqueous xanthan gum, 11 parts of KATHON LX SF25 and ion-exchanged water 13.8 parts were mixed to obtain Reference Example 6 (IPBC 2%, DCOIT 2%, BCM 2%, CMIT 2%).
（木材試験片を用いた糸状菌に対する試験）
実施例および比較例の木材用抗菌組成物を水で所定濃度になるように希釈し、この溶液中にベイマツ辺材（２ｃｍ×５ｃｍ×０．３ｃｍ）を３０秒間浸漬した後風乾した。この試験片をポテトデキストロース寒天培地上に載せ、供試菌の混合胞子懸濁液１ｍｌを噴霧し、２６℃、相対湿度９５％環境下で２８日間培養した。供試菌は、Ａｓｐｅｒｇｉｌｌｕｓ ｎｉｇｅｒ、Ｐｅｎｉｃｉｌｌｉｕｍ ｐｉｎｏｐｈｉｌｕｍ、Ａｕｒｅｏｂａｓｉｄｉｕｍ ｐｕｌｌｕｌａｎｓ、Ｃｌａｄｏｓｐｏｒｉｕｍ ｃｌａｄｏｓｐｏｒｉｏｉｄｅｓを用いた。
(Test for filamentous fungi using wood specimens)
The antibacterial compositions for wood of Examples and Comparative Examples were diluted with water to a predetermined concentration, and bay sapwood (2 cm × 5 cm × 0.3 cm) was immersed in this solution for 30 seconds and then air-dried. This test piece was placed on a potato dextrose agar medium, sprayed with 1 ml of a mixed spore suspension of the test bacteria, and cultured for 28 days in an environment of 26 ° C. and 95% relative humidity. As test bacteria, Aspergillus niger, Penicillium pinophilum, Aureobasidium pullulans, and Cladospodium clasporioides were used.
（木材試験片を用いた変色菌に対する試験）
ポテトデキストロース寒天培地上にエチレンオキサイド滅菌処理したベイマツ辺材試験体を置き、これに供試菌の混合胞子懸濁液１ｍｌを滴下し、２６℃、相対湿度９５％環境下１４日間前培養した。実施例および比較例の木材用抗菌組成物を水で所定濃度になるように希釈し、この溶液中にベイマツ辺材（２ｃｍ×５ｃｍ×０．３ｃｍ）を３０秒間浸漬した後風乾させた試験体を、前培養を終えた試験体の上に載せ、２６℃・相対湿度９５％環境下で２８日間培養した。供試菌は、Ｏｐｈｉｏｓｔｏｍａ ｐｉｃｅａｅ、Ｏｐｈｉｏｓｔｏｍａ ｐｉｌｉｆｅｒｕｍを用いた。
(Test for discoloration bacteria using wood specimens)
A pine sapwood specimen subjected to ethylene oxide sterilization treatment was placed on a potato dextrose agar medium, and 1 ml of a mixed spore suspension of the test bacteria was added dropwise thereto, and precultured at 26 ° C. and 95% relative humidity for 14 days. Test specimens obtained by diluting the antibacterial compositions for wood of Examples and Comparative Examples to a predetermined concentration with water, immersing bay sapwood (2 cm × 5 cm × 0.3 cm) in this solution for 30 seconds, and then air-drying Was placed on the test specimen that had been pre-cultured and cultured for 28 days in an environment of 26 ° C. and 95% relative humidity. As test bacteria, Ophiostoma picaee and Ophiostoma pilferum were used.
（木材試験片を用いた担子菌に対する試験）
ポテトデキストロース寒天培地上にエチレンオキサイド滅菌処理したベイマツ辺材試験体を置き、これに供試菌の混合胞子懸濁液１ｍｌを滴下し、２６℃、相対湿度９５％環境下１４日間前培養した。実施例および比較例の木材用抗菌組成物を水で所定濃度になるように希釈し、この溶液中にベイマツ辺材（２ｃｍ×５ｃｍ×０．３ｃｍ）を３０秒間浸漬した後風乾させた試験体を、前培養を終えた試験体の上に載せ、２６℃・相対湿度９５％環境下で２８日間培養した。供試菌は、Ｆｏｍｉｔｏｐｓｉｓ ｐａｌｕｓｔｒｉｓを用いた。
(Test for basidiomycetes using wood specimens)
A pine sapwood specimen subjected to ethylene oxide sterilization treatment was placed on a potato dextrose agar medium, and 1 ml of a mixed spore suspension of the test bacteria was added dropwise thereto, and precultured at 26 ° C. and 95% relative humidity for 14 days. Test specimens obtained by diluting the antibacterial compositions for wood of Examples and Comparative Examples to a predetermined concentration with water, immersing bay sapwood (2 cm × 5 cm × 0.3 cm) in this solution for 30 seconds, and then air-drying Was placed on the test specimen that had been pre-cultured and cultured for 28 days in an environment of 26 ° C. and 95% relative humidity. As the test bacterium, Fomitopsis palustris was used.
これらの試験結果を表１に示した。これらの結果から本発明の抗菌組成物は糸状菌、変色菌、担子菌いずれに対しても良好な抗菌性を示すことがわかる。 The test results are shown in Table 1. From these results, it can be seen that the antibacterial composition of the present invention exhibits good antibacterial properties against all filamentous fungi, discoloration bacteria, and basidiomycetes.
１：試験片上の供試菌の発育面積は全面積の１／３未満である。
２：試験片上の供試菌の発育面積は全面積の１／３以上である。
1: The growth area of the test bacteria on the test piece is less than 1/3 of the total area.
2: The growth area of the test bacteria on the test piece is 1/3 or more of the total area.
本発明の木材用抗菌組成物は、５−クロロ−２−メチル−４−イソチアゾリン−３−オンおよび／またはその金属錯塩と、３−ヨード−２−プロピニルブチルカーバメートと、特定のイソチアゾロン化合物またはベンズイミダゾール系化合物から選ばれる一種以上の化合物、を必須成分として含有することを特徴とする木材用抗菌組成物であり、糸状菌だけでなく変色菌や担子菌を含む幅広い真菌から、少ない使用量で木材および木材製品を保護することが可能であるため産業の発展に寄与するものである。
The antibacterial composition for wood of the present invention comprises 5-chloro-2-methyl-4-isothiazolin-3-one and / or a metal complex thereof, 3-iodo-2-propynylbutyl carbamate, a specific isothiazolone compound or benz It is an antibacterial composition for wood characterized by containing one or more compounds selected from imidazole compounds as essential components, and it can be used in a small amount from a wide range of fungi including discolored and basidiomycetes as well as filamentous fungi. It can contribute to industrial development because it can protect wood and wood products.
Claims (2)
ｂ）３−ヨード−２−プロピニルブチルカーバメートと、
ｃ）２−ｎ−オクチル−４−イソチアゾリン−３−オン、Ｎ−ｎ−ブチル−１，２−ベンズイソチアゾリン−３−オン、および／または２−（４−チアゾリル）ベンズイミダゾールから選ばれる一種以上の化合物を必須成分として含有することを特徴とする木材用抗糸状菌用、抗変色菌用、および抗担子菌用組成物。 a) 5-chloro-2-methyl-4-isothiazolin-3-one and / or a metal complex thereof;
b) 3-iodo-2-propynyl butyl carbamate;
c) one or more selected from 2-n-octyl-4-isothiazolin-3-one, Nn-butyl-1,2-benzisothiazolin-3-one, and / or 2- (4-thiazolyl) benzimidazole A composition for anti-filamentous fungi for wood, for anti-discoloring fungi, and for anti-basidiomycetes, comprising the above compound as an essential component.
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| JP2007191437A (en) * | 2006-01-19 | 2007-08-02 | Nippon Soda Co Ltd | Antiseptic or antifungal agent composition and method for producing antiseptic or antifungal dried wood |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH01311006A (en) * | 1988-06-08 | 1989-12-15 | Ichikawa Gosei Kagaku Kk | Industrial antimicrobial and antifungal agent |
| JPH02221203A (en) * | 1988-12-22 | 1990-09-04 | Rohm & Haas Co | Microbicidal composition |
| JPH03251508A (en) * | 1990-02-26 | 1991-11-11 | Shinto Paint Co Ltd | Industrial fungicide composition |
| JPH0616506A (en) * | 1992-06-30 | 1994-01-25 | Shinto Paint Co Ltd | Industrial antifungal composition |
| JPH07133206A (en) * | 1993-11-10 | 1995-05-23 | Hokko Chem Ind Co Ltd | Industrial preservative fungicide |
| JPH10298012A (en) * | 1997-04-22 | 1998-11-10 | Takeda Chem Ind Ltd | Microbicide composition and control of microorganism |
| JPH11189507A (en) * | 1997-12-25 | 1999-07-13 | Somar Corp | Harmful microorganism exterminator |
| JP2004524263A (en) * | 2000-08-21 | 2004-08-12 | トール ゲーエムベーハー | Synergistic biocide composition |
| JP2005281305A (en) * | 2004-03-05 | 2005-10-13 | Rohm & Haas Co | ANTIMICROBIAL COMPOSITION COMPRISING N-(n-BUTYL)-1,2-BENZISOTHIAZOLIN-3-ONE |
| JP2007191437A (en) * | 2006-01-19 | 2007-08-02 | Nippon Soda Co Ltd | Antiseptic or antifungal agent composition and method for producing antiseptic or antifungal dried wood |
| JP2010525011A (en) * | 2007-04-27 | 2010-07-22 | ランクセス・ドイチュランド・ゲーエムベーハー | Active ingredient formulation comprising 2-thiazol-4-yl-1H-benzimidazole (thiabendazole or TBZ) for the manufacture of WPC |
| JP2013035790A (en) * | 2011-08-09 | 2013-02-21 | Japan Enviro Chemicals Ltd | Agent for removing microbe |
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