JP2010533565A - ヒドロゲルの拡張能力を備えた眼内植込み体 - Google Patents
ヒドロゲルの拡張能力を備えた眼内植込み体 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0061—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0085—Identification means; Administration of patients
- A61F2250/0087—Identification means; Administration of patients colour-coded
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Abstract
【解決手段】植込み体は、延長部材に取り付けられるヒドロゲル部材であって、眼内に延長部材を植設すると続いて拡張するように構成されているヒドロゲル部材を具備する。アタッチメントが、ヒドロゲル部材を延長部材に取り付ける。
Description
典型的な眼の解剖学的形態
植込み体及び導入システム
典型的な導入方法及び植設方法
植込み体及び導入システムの他の実施形態
方法の追加説明
輸液
閉塞隅角緑内障に用いる植込み体
植込み体の経強膜導入
拡張部材及び拡張材料
植込み体の他の実施形態
110 近位端
120 遠位端
305 内部管腔
410 係止構造物
510 導入システム(ハンドルコンポーネント)
520 導入コンポーネント
525 移植具
530 送出し構造物
550 つまみ
705 スロット
910 拡張部材
1005 係止部材
1010 孔
1405 観察用レンズ
2205 コア
2405 ステント
2410 プラグ部材
3310 歯
3405 スリーブ
3605 スリーブ
3705 コイル
3805 把持ループ
4005 スネア(snare)
4305 弾性領域
4405 外延部
5252 移植具
5305 先端部材
5405 心棒
5410 近位領域
5615 脚部
5620 連結部材
5701 導入経路
6410 外筒
6610 係着部材
7205 係着部材
7210 外筒領域
7805 作動部材
8210 拡張可能部材
9205 拡張部材
9310 外筒
9705 指状部材
9805 領域
AC 前眼房
H ヒドロゲル
I 虹彩
L レンズ
PC 後眼房
R 網膜
Claims (25)
- 流動経路を形成する内部管腔を有し、少なくとも1つの流入ポートが前記流動経路と連通し、少なくとも1つの流出ポートが前記流動経路と連通する延長部材であって、少なくとも1つの流入ポートが前眼房と連通し、少なくとも1つの流出ポートが脈絡膜上腔と連通し、前記前眼房と前記脈絡膜上腔との間に液体路を提供するような形で眼内に配設されるように構成されている延長部材と、
前記延長部材に取り付けられるヒドロゲル部材であって、眼内に延長部材を植設すると続いて拡張するように構成されているヒドロゲル部材と、
前記ヒドロゲル部材を前記延長部材に取り付けるアタッチメントと、
を備えていることを特徴とする眼内植込み体。 - 前記アタッチメントが前記延長部材上にアクリル樹脂の層を備え、前記アクリル樹脂が前記ヒドロゲル部材に取り付けられていることを特徴とする、請求項1に記載の眼内植込み体。
- 前記アクリル樹脂が前記ヒドロゲル部材に共有結合されていることを特徴とする、請求項2に記載の眼内植込み体。
- 前記アクリル樹脂が、重合化工程に従って前記ヒドロゲル部材に共有結合されていることを特徴とする、請求項2に記載の眼内植込み体。
- 前記アタッチメントが、前記ヒドロゲル部材と前記延長部材との間に機械的アタッチメントを備えていることを特徴とする、請求項1に記載の眼内植込み体。
- 前記機械的アタッチメントが、前記延長部材に取り付けられるケージを備え、
前記ヒドロゲル部材が前記ケージの内部に配設されていることを特徴とする、請求項5に記載の眼内植込み体。 - 前記ヒドロゲル部材が、前記ケージのスロットを通って拡張することを特徴とする、請求項6に記載の眼内植込み体。
- 前記延長部材が多孔性であり、
前記アタッチメントは、前記延長部材の複数の細孔を含み、
前記ヒドロゲル部材が少なくとも部分的に前記細孔に配設されていることを特徴とする、請求項1に記載の眼内植込み体。 - 前記ヒドロゲル部材が前記細孔内で重合化されることを特徴とする、請求項8に記載の眼内植込み体。
- 前記アタッチメントが、前記ヒドロゲル部材及び前記延長部材上にコートされた半透過性膜を備えていることを特徴とする、請求項1に記載の眼内植込み体。
- 拡張時に前記膜が前記ヒドロゲルと一緒に拡張して前記ヒドロゲルを前記延長部材に係止することを特徴とする、請求項10に記載の眼内植込み体。
- 前記ヒドロゲル部材が前記膜を介して水和できるようにするために、前記膜が透水性であることを特徴とする、請求項10に記載の眼内植込み体。
- 前記ヒドロゲル上に配設された再吸収可能コーティングを更に備えていることを特徴とする、請求項1に記載の眼内植込み体。
- 前記再吸収可能コーティングが前記ヒドロゲル部材の拡張速度を調節することを特徴とする、請求項13に記載の眼内植込み体。
- 前記ヒドロゲル部材が拡張すると続いて前記コーティングが破裂することを特徴とする、請求項13に記載の眼内植込み体。
- 前記ヒドロゲル部材が、前記延長本体上に配設された外筒であることを特徴とする、請求項1に記載の眼内植込み体。
- 前記管状部材上に配設された一対のプレートを更に備え、
前記ヒドロゲル部材が前記プレート間に配設されていることを特徴とする、請求項1に記載の眼内植込み体。 - 前記ヒドロゲル部材が拡張すると続いて前記ヒドロゲル部材が前記植込み体の一部分を移動せしめることを特徴とする、請求項1に記載の眼内植込み体。
- 眼内デバイスを眼の中に植設する方法であって、
内部液体路を有する植込み体であって、少なくとも一部が拡張可能材料で製造されている植込み体を提供することと、
前記液体路の第1の部分が前眼房と連通し、前記液体路の第2の部分が脈絡膜上腔と連通して、前記脈絡膜上腔と前記前眼房との間に液体路を提供するように前記植込み体を眼の中に挿入することと、
前記拡張可能材料が前記植込み体に隣接する液体路を封着するように前記拡張可能材料を拡張させることと、
を含むことを特徴とする方法。 - 前記拡張可能材料がヒドロゲル又は超弾性材料であることを特徴とする、請求項19に記載の方法。
- 眼内デバイスを眼の中に植設する方法であって、
内部液体路を有する植込み体であって、少なくとも一部が拡張可能材料で製造されている作動部材を具備する植込み体を提供することと、
前記液体路の第1の部分が前眼房と連通し、前記液体路の第2の部分が脈絡膜上腔と連通して、前記脈絡膜上腔と前記前眼房との間に液体路を提供するように前記植込み体を眼の中に挿入することと、
前記作動部材が前記植込み体の可動部を第1の位置から第2の位置に移動せしめるように、前記拡張可能材料を拡張させることと、
を含むことを特徴とする方法。 - 眼内デバイスを眼の中に植設する方法であって、
内部液体路を有する植込み体であって、少なくとも一部が拡張可能材料で製造されている作動部材を具備する植込み体を提供することと、
前記液体路の第1の部分が前眼房と連通し、前記液体路の第2の部分が脈絡膜上腔と連通して、前記脈絡膜上腔と前記前眼房との間に液体路を提供するように前記植込み体を眼の中に挿入することと、
前記作動部材が眼組織を第1の位置から第2の位置に移動せしめるように、前記拡張可能材料を拡張させることと、
を含むことを特徴とする方法。 - 前記移動時に前記眼組織が解離されることを特徴とする、請求項22に記載の方法。
- 眼内デバイスを眼の中に植設する方法であって、
内部液体路を有する植込み体であって、少なくとも一部が拡張可能材料で製造されている作動部材を具備する植込み体を提供することと、
前記液体路の第1の部分が前眼房と連通し、前記液体路の第2の部分が脈絡膜上腔と連通して、前記脈絡膜上腔と前記前眼房との間に液体路を提供するように前記植込み体を眼の中に挿入することと、
部分的に包囲された容積が前記脈絡膜上腔内に形成されるように、前記拡張可能材料を拡張させることと、
を含むことを特徴とする方法。 - 眼内デバイスを眼の中に植設する方法であって、
内部液体路を有するシャントであって、少なくとも一部がヒドロゲルで製造されているシャントを提供することと、
前記液体路の第1の部分が前眼房と連通し、前記液体路の第2の部分が脈絡膜上腔と連通して、前記脈絡膜上腔と前記前眼房との間に液体路を提供するように前記シャントを眼の中に挿入することと、
前記ヒドロゲルが眼組織に係着して眼内の所定位置に前記シャントを係止するように、前記ヒドロゲルを拡張させることと、
を含むことを特徴とする方法。
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US95031507P | 2007-07-17 | 2007-07-17 | |
US60/950,315 | 2007-07-17 | ||
PCT/US2008/070364 WO2009012406A1 (en) | 2007-07-17 | 2008-07-17 | Ocular implant with hydrogel expansion capabilities reference to priority document |
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JP2010533565A5 JP2010533565A5 (ja) | 2011-09-01 |
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US20120220917A1 (en) | 2012-08-30 |
WO2009012406A1 (en) | 2009-01-22 |
US20090182421A1 (en) | 2009-07-16 |
US8672870B2 (en) | 2014-03-18 |
EP2173289A4 (en) | 2010-11-24 |
JP5328788B2 (ja) | 2013-10-30 |
EP2173289A1 (en) | 2010-04-14 |
US9585789B2 (en) | 2017-03-07 |
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