JP2006526624A5 - - Google Patents
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- Publication number
- JP2006526624A5 JP2006526624A5 JP2006509816A JP2006509816A JP2006526624A5 JP 2006526624 A5 JP2006526624 A5 JP 2006526624A5 JP 2006509816 A JP2006509816 A JP 2006509816A JP 2006509816 A JP2006509816 A JP 2006509816A JP 2006526624 A5 JP2006526624 A5 JP 2006526624A5
- Authority
- JP
- Japan
- Prior art keywords
- dispersion
- container
- nanoparticles
- aerosol
- propellant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008342 pharmaceutical dispersion Substances 0.000 claims 4
- 239000000443 aerosol Substances 0.000 claims 3
- 239000002105 nanoparticle Substances 0.000 claims 3
- 239000006185 dispersion Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drugs Drugs 0.000 claims 2
- 239000007791 liquid phase Substances 0.000 claims 2
- 239000003380 propellant Substances 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 229940071648 Metered Dose Inhaler Drugs 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000000087 stabilizing Effects 0.000 claims 1
Claims (4)
- 薬を含んでなる分散した固相、および
噴霧剤および賦形剤ナノ粒子を含んでなる連続液相
を含み、前記ナノ粒子が100nm未満の平均粒子直径を有する、安定した医薬品分散体。 - 計量バルブを有する煙霧剤容器、および
容器内に配置された請求項1に記載の安定した医薬品分散体
を含んでなる定量吸入器。 - 煙霧剤容器を提供するステップと、
前記容器に請求項1に記載の医薬品分散体を装填するステップと、
を含んでなる、煙霧剤分散体を製造する方法。 - 薬を含んでなる分散した固相と、噴霧剤を含んでなる連続液相とを含んでなる分散体に、有効量のナノ粒子を添加するステップを含んでなる、医薬品分散体を安定化する方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/449,443 US7459146B2 (en) | 2003-05-30 | 2003-05-30 | Stabilized aerosol dispersions |
PCT/US2004/010847 WO2004108118A1 (en) | 2003-05-30 | 2004-04-08 | Stabilized aerosol dispersions |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2006526624A JP2006526624A (ja) | 2006-11-24 |
JP2006526624A5 true JP2006526624A5 (ja) | 2007-05-24 |
JP4680894B2 JP4680894B2 (ja) | 2011-05-11 |
Family
ID=33451787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006509816A Expired - Fee Related JP4680894B2 (ja) | 2003-05-30 | 2004-04-08 | 安定化させた煙霧剤分散体 |
Country Status (6)
Country | Link |
---|---|
US (1) | US7459146B2 (ja) |
EP (1) | EP1628645A1 (ja) |
JP (1) | JP4680894B2 (ja) |
KR (1) | KR20060038938A (ja) |
CN (1) | CN1798549B (ja) |
WO (1) | WO2004108118A1 (ja) |
Families Citing this family (31)
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US7109247B2 (en) * | 2003-05-30 | 2006-09-19 | 3M Innovative Properties Company | Stabilized particle dispersions containing nanoparticles |
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KR100961280B1 (ko) | 2008-05-21 | 2010-06-03 | 한국생명공학연구원 | 형광특성이 향상된 풀러렌-실리카 나노입자, 이의 제조방법및 이의 용도 |
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EP2646107A2 (en) | 2010-12-01 | 2013-10-09 | Spinal Modulation Inc. | Agent delivery systems for selective neuromodulation |
US10723628B2 (en) | 2015-07-10 | 2020-07-28 | Evonik Operations Gmbh | SiO2 containing dispersion with high salt stability |
EP3319907B1 (de) | 2015-07-10 | 2020-08-05 | Evonik Operations GmbH | Sio2 enthaltende dispersion mit hoher salzstabilität |
EP3319905A1 (de) | 2015-07-10 | 2018-05-16 | Evonik Degussa GmbH | Metalloxid enthaltende dispersion mit hoher salzstabilität |
EP3368633B1 (en) | 2015-10-26 | 2020-05-27 | Evonik Operations GmbH | Method of obtaining mineral oil using a silica fluid |
SG11202100580UA (en) | 2018-07-23 | 2021-02-25 | Trevi Therapeutics Inc | Treatment of chronic cough, breathlessness and dyspnea |
WO2024137511A1 (en) * | 2022-12-20 | 2024-06-27 | The Regents Of The University Of Michigan | High density microarrays and uses thereof |
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US7459146B2 (en) * | 2003-05-30 | 2008-12-02 | 3M Innovative Properties Company | Stabilized aerosol dispersions |
US7109247B2 (en) | 2003-05-30 | 2006-09-19 | 3M Innovative Properties Company | Stabilized particle dispersions containing nanoparticles |
-
2003
- 2003-05-30 US US10/449,443 patent/US7459146B2/en not_active Expired - Fee Related
-
2004
- 2004-04-08 JP JP2006509816A patent/JP4680894B2/ja not_active Expired - Fee Related
- 2004-04-08 CN CN2004800150751A patent/CN1798549B/zh not_active Expired - Fee Related
- 2004-04-08 EP EP04749884A patent/EP1628645A1/en not_active Withdrawn
- 2004-04-08 KR KR1020057022771A patent/KR20060038938A/ko not_active Application Discontinuation
- 2004-04-08 WO PCT/US2004/010847 patent/WO2004108118A1/en active Application Filing
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