JP2003095986A - Composition containing gymnema sylvestre extract and having reduced bitterness - Google Patents

Composition containing gymnema sylvestre extract and having reduced bitterness

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Publication number
JP2003095986A
JP2003095986A JP2001292333A JP2001292333A JP2003095986A JP 2003095986 A JP2003095986 A JP 2003095986A JP 2001292333 A JP2001292333 A JP 2001292333A JP 2001292333 A JP2001292333 A JP 2001292333A JP 2003095986 A JP2003095986 A JP 2003095986A
Authority
JP
Japan
Prior art keywords
extract
gymnema
gymnema sylvestre
bitterness
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001292333A
Other languages
Japanese (ja)
Inventor
Keiji Terao
啓二 寺尾
Yoshikazu Inoue
良計 井上
Teruyuki Kaneda
輝之 金田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bizen Chemical Co Ltd
Original Assignee
Bizen Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bizen Chemical Co Ltd filed Critical Bizen Chemical Co Ltd
Priority to JP2001292333A priority Critical patent/JP2003095986A/en
Publication of JP2003095986A publication Critical patent/JP2003095986A/en
Pending legal-status Critical Current

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  • Medicines Containing Plant Substances (AREA)

Abstract

PROBLEM TO BE SOLVED: To obtain a composition containing a Gymnema sylvestre extract and suppressed in astringent bitterness peculiar to the Gymnema sylvestre. SOLUTION: This composition contains the Gymnema sylvestre extract which is obtained by acid deposition treatment and, optionally purification treatment of the solid Gymnema sylvestre extract in water and then including the thus treated solid extract with a cyclodextrin.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【発明の属する技術分野】ギムネマ・シルベスタ(Gymne
ma sylvestre)抽出物をγ−シクロデキストリンで包接
してなるギムネマ・シルベスタ抽出物を含む苦味のない
組成物に関する。
TECHNICAL FIELD The invention belongs to Gymnema Sylvester.
and a non-bitter composition comprising Gymnema sylvestre extract obtained by encapsulating a gamma-cyclodextrin.

【0002】[0002]

【従来の技術】ギムネマ・シルベスタはインド、東南ア
ジア、中国などに自生するガガイモ科に属する植物で、
その水またはアルコール抽出物は甘味抑制効果があるこ
とや、腸管による糖吸収抑制効果のあることが知られて
いる。ギムネマ・シルベスタの有するこのような効果を
示す有効成分はギムネマ酸であるといわれている。ギム
ネマ・シルベスタ抽出物は収斂性のある苦味を有し砂糖
その他の甘味物質について感じる感覚を抑制し、これを
摂取した後はしばらくの間甘さを感じなくなるため、他
の飲食物の呈味を損なう。
[Background Art] Gymnema sylvestre is a plant belonging to the family Potato, which grows naturally in India, Southeast Asia and China.
It is known that the water or alcohol extract has a sweetness suppressing effect and a sugar absorption suppressing effect by the intestinal tract. It is said that Gymnema acid is the active ingredient which has such an effect that Gymnema sylvestre has. Gymnema sylvestre extract has an astringent bitterness and suppresses the sensation of sugar and other sweet substances, and after ingesting it, it loses its sweetness for a while. Spoil.

【0003】このため、その苦味を低減する方法が提案
されている。その一つとしてギムネマ・シルベスタ抽出
物にシクロデキストリン(以下、CD)を添加し、さらに
必要に応じて呈味改善剤を添加した飲料が特開昭63−
105661号公報に開示されている。特開昭63−1
05661号公報によると、ギムネマ・シルベスタを
水、水−アルコール、低級ケトンなどを抽出溶媒として
加熱処理した抽出液から溶媒を除去して乾燥物としたも
のを再度水に溶解して、この0.2重量%溶液に0.5〜25倍
重量、好ましくは5〜10倍重量のCDを添加している。
そしてCDはα、β、γ−CDのいずれでもCDを添加
しないものに比べて呈味改善の効果があるとされてい
る。さらに、特開平1−120263号公報には、ギム
ネマ・シルベスタ抽出物を含有する糖組成物として、ギ
ムネマ・シルベスタ抽出物を含有する液体を分岐型CD
で包接した包接体および糖類を必須成分とする糖組成物
が提案されており、この場合、CDは分岐型CDのほ
か、α、β、γ−CDを適宜選択して用いることができ
るとされている。
Therefore, a method for reducing the bitterness has been proposed. As one of them, there is a beverage prepared by adding cyclodextrin (hereinafter referred to as CD) to Gymnema sylvestre extract and, if necessary, a taste improver.
It is disclosed in Japanese Patent No. 105661. JP 63-1
According to the No. 05661 publication, Gymnema sylvestre is heat-treated with water, water-alcohol, lower ketone, etc. as an extraction solvent to remove the solvent from the extract, and the dried product is dissolved again in water. % Solution is added with 0.5 to 25 times by weight, preferably 5 to 10 times by weight of CD.
It is said that CD has an effect of improving taste as compared with the case where CD is not added in any of α, β and γ-CD. Further, in JP-A-1-120263, a sugar composition containing a Gymnema sylvestre extract is prepared as a branched CD containing a liquid containing a Gymnema sylvestre extract.
A saccharide composition containing an inclusion body and a saccharide as an essential component has been proposed. In this case, in addition to branched CD, α, β, γ-CD can be appropriately selected and used as CD. It is said that.

【0004】一方、特開昭64−2552号公報には、
CDにはα、β、γの3つの型があるが、包接して苦味
を抑える効果のあるのはγ型のみであることが記載さ
れ、特開昭64−2552号公報によると、ギムネマ・
シルベスタ抽出物精製品である粗ギムネマ酸の5重量倍
以上の澱粉の存在下でシクロデキストリン・グルコシル
・トランスフェラーゼを作用させて粗ギムネマ酸にグル
コース転移を生じ、次いで過剰の澱粉から生成するγ−
CDが粗ギムネマ酸を包接することにより苦味が低減さ
れるものと考えられている。この方法で苦味を感じなく
させるためには、粗ギムネマ酸100mgについて澱粉1500m
gを要し、このとき生成するγ−CDは133mgであり、粗
ギムネマ抽出物とγ−CDの日は実質的に等モルと考え
られると述べている。
On the other hand, Japanese Patent Laid-Open No. 64-2552 discloses that
There are three types of CD, α, β, and γ, but it is described that only the γ type has the effect of clathrating and suppressing bitterness. According to Japanese Patent Laid-Open No. 64-2552, Gymnema
Cyclodextrin glucosyl transferase is allowed to act in the presence of starch in an amount of 5 times as much as that of crude Gymnemic acid, which is a purified product of Sylvestre extract, to cause glucose transfer to crude Gymnemic acid, and then γ-produced from excess starch
It is believed that bitterness is reduced by the inclusion of crude gymnematic acid by CD. In order to eliminate the bitterness with this method, 100 g of crude Gymnemaic acid should be added to 1500 m of starch.
g, and the γ-CD produced at this time is 133 mg, and it is stated that the days of crude Gymnema extract and γ-CD are considered to be substantially equimolar.

【0005】本発明者等もこれら先行技術を参考に苦味
低減を試みたが、粗ギムネマ抽出物の存在下澱粉の酵素
分解という過程を経ることなく粗ギムネマ抽出物にその
3重量倍の市販のγ−CDを使用しても十分にはその苦
味は低減されなかった。他方、ギムネマ酸の利用に関し
て、ギムネマ酸の生理活性に着目した種々の飲食品が提
案されている。例えば、ギムネマ・シルベスタの乾燥葉
に焙煎処理した茶(血糖値上昇抑制作用と抗齲蝕作用−
特公平3−78846号公報)、低カロリー飲食物(糖吸収
抑制効果−特公平5−53468号公報)、肥満防止能を有
する高脂質食品(脂質の腸管からの吸収遅延−特開平6
−343421号公報)などが提案されている。
The inventors of the present invention also tried to reduce bitterness by referring to these prior arts, but the crude Gymnema extract was obtained without the process of enzymatic decomposition of starch in the presence of the crude Gymnema extract.
Even if 3 times the weight of commercially available γ-CD was used, the bitterness was not sufficiently reduced. On the other hand, regarding the use of gymnematic acid, various foods and drinks have been proposed, focusing on the physiological activity of gymnemic acid. For example, dried tea leaves of Gymnema sylvestre roasted tea (blood sugar level increase inhibitory effect and anti-caries effect-
Japanese Patent Publication No. 3-78846), low-calorie foods and drinks (sugar absorption inhibitory effect-Japanese Patent Publication No. 5-53468), and high-fat foods with obesity-preventing ability (delayed absorption of lipids from the intestinal tract) -Patent Application 20060187100
-343421 gazette) etc. are proposed.

【0006】[0006]

【発明が解決しようとする課題】本発明者等は、上述の
ように種々の生理活性を有するギムネマ・シルベスタ抽
出物を家庭等においても、ギムネマ・シルベスタ特有の
収斂性のある苦味を伴うことなく、種々の飲食物に容易
に添加し摂取できるようにするべく研究した結果、ギム
ネマ・シルベスタ抽出物として、ギムネマ・シルベスタ
の溶媒抽出物をさらに水中で酸析処理して得られるギム
ネマ・シルベスタ抽出物をその2重量倍以上のγ−CD
で包接することによって家庭等で取り扱いの容易な組成
物とし得ることを見出し本発明に到った。
DISCLOSURE OF THE INVENTION The inventors of the present invention can obtain a Gymnema sylvestre extract having various physiological activities as described above without causing astringent bitterness peculiar to Gymnema sylvesta even at home. , As a result of research to make it easy to add to various foods and drinks, a Gymnema sylvester extract obtained by further acidifying a Gymnema sylvester solvent extract in water as a Gymnema sylvester extract 2 times the weight of γ-CD
It was found that a composition that can be easily handled at home or the like can be obtained by wrapping it in the composition.

【0007】[0007]

【課題を解決するための手段】本発明は、ギムネマ・シ
ルベスタ抽出物として、ギムネマ・シルベスタの溶媒抽
出物をさらに水中で酸析処理して得られるギムネマ・シ
ルベスタ抽出物(固形分)重量の2倍重量以上のγ−C
Dを用いて包接してなるギムネマ・シルベスタ抽出物を
含む組成物に関する。またこれを顆粒状またはゼリー状
にした組成物を包装した飲食品添加用包装体に関する。
特にギムネマ・シルベスタ抽出物とγ−CDのみからな
る、または本質的に調理済みの飲食物の味に影響を与え
る成分を含有させない顆粒とするときは、調理済みの飲
食物に添加してその味を変えることなく、ギムネマ酸を
摂取することができる。
The present invention provides, as a Gymnema sylvester extract, a Gymnema sylvester extract (solid content) obtained by further subjecting a solvent extract of Gymnema sylvester to an acid precipitation treatment in water. Double weight or more γ-C
The present invention relates to a composition containing Gymnema sylvestre extract clathrated with D. The present invention also relates to a package for adding food and drink, which is obtained by packaging a composition in the form of granules or jelly.
In particular, when the granules consist of Gymnema sylvestre extract and γ-CD alone, or do not contain ingredients that essentially affect the taste of cooked food and drink, they are added to the cooked food and drink to taste the same. You can take Gymnemic Acid without changing.

【0008】[0008]

【発明の実施の形態】本発明で用いるギムネマ・シルベ
スタ抽出物は、ギムネマ・シルベスタの乾燥葉または生
葉を温湯水またはアルコール等によって抽出し、抽出液
より溶媒を除去して得られる。例えば、特開平6−1137
92号公報に記載されているように、ギムネマ・シルベス
タの乾燥葉を60℃の温湯中に5時間以上浸し、次いで回
転数1200〜1300rpmにて軽く遠沈して、その後残渣を除
去した上澄み液を凍結乾燥法やスプレードライ法などに
より粉末状抽出物とし、さらにこの抽出成分を水に溶解
し、その溶液をpH3に調整してその析出物として得る
ことができる。また、該公報によると、このような抽出
物は好ましくは精製して用いるが、その精製の程度によ
って不純物と共にギムネマ酸を含むか、またはギムネマ
酸のみから構成される。また、ギムネマ・シルベスタの
乾燥葉または生葉を温湯水またはアルコール等によって
抽出する工程でギムネマ・シルベスタに作用する細胞膜
溶解酵素を作用させて抽出した抽出液を酸析処理した抽
出物、またはさらに精製処理を施して不純物を除去する
ギムネマ酸の製造方法も提案されている(特開平6−6287
4号公報)。本発明ではこのような従来技術で得られるギ
ムネマ酸抽出物をいずれも用いることができるが、高度
に精製されたものが好ましい。
BEST MODE FOR CARRYING OUT THE INVENTION The Gymnema sylvestre extract used in the present invention is obtained by extracting dried leaves or fresh leaves of Gymnema sylvestre with hot water or alcohol and removing the solvent from the extract. For example, Japanese Patent Laid-Open No. 6-1137
As described in Japanese Patent Publication No. 92, the dried leaves of Gymnema sylvestre are soaked in hot water at 60 ° C for 5 hours or longer, and then lightly spun down at a rotation speed of 1200 to 1300 rpm, and the residue is then removed to obtain a supernatant liquid. Can be obtained as a powdery extract by a freeze-drying method, a spray-drying method, or the like, and the extracted components are dissolved in water, and the solution is adjusted to pH 3 to obtain the precipitate. Further, according to the publication, such an extract is preferably used after being purified, but depending on the degree of purification, it contains gymnemic acid together with impurities or is composed only of gymnemic acid. Also, an extract obtained by acidifying an extract obtained by acting a cell membrane-dissolving enzyme acting on Gymnema sylvester in the step of extracting dried leaves or fresh leaves of Gymnema sylvester with hot water or alcohol, or further purification treatment There is also proposed a method for producing gymnemic acid in which impurities are removed by applying the treatment (JP-A-6-6287).
(Gazette No. 4). In the present invention, any gymnematic acid extract obtained by such a conventional technique can be used, but highly purified one is preferable.

【0009】本発明では、上述のギムネマ・シルベスタ
の溶媒抽出物を水溶液とし、これに塩酸または硫酸など
を用いてそのpHを3程度にして得られる沈降物あるいは
その更なる精製物(以下、これらを「ギムネマ抽出物」
と記す)を用いる。γ−CDをギムネマ抽出物の2倍重
量以上添加混合することにより、ギムネマ抽出物をγ−
CDで包接体を生成させる。
In the present invention, the above-mentioned solvent extract of Gymnema sylvestre is made into an aqueous solution, and a precipitate obtained by adjusting the pH to about 3 using hydrochloric acid or sulfuric acid, or a further purified product thereof (hereinafter, these "Gymnema extract"
Will be used). The Gymnema extract was mixed with γ-CD by adding at least twice the weight of Gymnema extract and mixing.
Generate an inclusion body with a CD.

【0010】本発明者等の研究によると、苦味抑制効果
はα−CD、β−CDではギムネマ抽出物の3重量倍用い
た場合でも殆どないが、γ−CDではギムネマ抽出物と
等量用いたときはその苦味は約1/10に抑えられ、2重
量倍用いると苦味を殆ど感じさせなくなり、3重量倍用
いたときは苦味を全く感じさせなくなる。従って、本発
明では、ギムネマ抽出物を2重量倍以上、好ましくは2.
5〜5重量倍、さらに好ましくは2.5〜3.5重量倍のγ−
CDを用いて包接した包接体とする。2重量倍より少な
いとギムネマ酸特有の苦味を呈して好ましくない。3重
量倍用いた包接体では苦味を全く感じさせなくなる。そ
れ以上に多量に用いるのは得策ではない。5重量倍以下
がよい。
According to the study by the present inventors, the bitterness-suppressing effect is almost non-existent in α-CD and β-CD even when 3 times by weight of Gymnema extract is used, but in γ-CD, it is equivalent to Gymnema extract. The bitterness is suppressed to about 1/10 when it is used, and when 2 times by weight is used, the bitterness is hardly felt, and when it is used 3 times by weight, the bitterness is not felt at all. Therefore, in the present invention, the Gymnema extract is more than 2 times by weight, preferably 2.
5 to 5 times by weight, more preferably 2.5 to 3.5 times by weight γ-
A clathrate is included by using a CD. If it is less than 2 times by weight, the bitterness peculiar to gymnemic acid is exhibited, which is not preferable. The clathrate used at 3 times the weight gives no bitterness. It is not a good idea to use more than that. 5 times or less is preferable.

【0011】本発明では、粉体として得られる上記の組
成物を単独で、または水溶性の補助成分と共に、通常の
製剤技術などを用いて顆粒状にし、スティック状その他
種々の包装体とする。特にギムネマ抽出物とγ−CDの
みからなる、または調理済みの食物の味に影響を与える
成分を含有させない顆粒とするときは、調理済みの食物
に添加してその味を変えることなく、ギムネマ酸を摂取
することができ好ましい。包装体に入れる本発明の組成
物の量はその用途に応じて、すなわち、目的とするギム
ネマ酸の有する効能、使用方法に異なる。例えば、糖の
吸収を抑制するべく、飲料時において清涼飲料水等への
添加用としては、1〜10g、またギムネマ酸は脂質の加
水分解物の腸管からの吸収を抑制するといわれ、高脂質
食品の調製に当たり、その含有脂質量の0.01〜0.1重量
%添加すると効果があると言われている(特開平6−343
421)。家庭におけるこのような用途にも1〜10gという
量は適している。
In the present invention, the above-mentioned composition obtained as a powder is granulated into a stick form or other various packaging bodies by using a conventional formulation technique alone or together with a water-soluble auxiliary component. In particular, when the granules consist of Gymnema extract and γ-CD alone or do not contain ingredients that affect the taste of cooked foods, Gymnema acid is added to cooked foods without changing its taste. Can be ingested and is preferable. The amount of the composition of the present invention to be put in the package differs depending on its use, that is, the desired effect of gymnemic acid and the method of use. For example, in order to suppress the absorption of sugar, as an additive to soft drinks at the time of drinking, 1 to 10 g, and gymnematic acid is said to suppress absorption of lipid hydrolysates from the intestinal tract. It is said that the addition of 0.01 to 0.1% by weight of the lipid content is effective in the preparation of (Japanese Unexamined Patent Publication No. 6-343).
421). Amounts of 1 to 10 g are also suitable for such home applications.

【0012】また、本発明では、ギムネマ酸抽出物をゼ
リー状の製品として用いることができる。ゼリー状製品
の製造はゲル化剤としてゼラチン、寒天、ペクチン、ア
ルギン酸誘導体などを用いる通常のゼリー状製品の製造
技術によればよく、このときは他の呈味成分を加えても
よく、果糖ブドウ糖糖液、オリゴ糖、酸味料、クエン酸
ナトリウム、ビタミン類、オレンジ果汁、甘味料、香料
などを加えることができる。以下の実施例で溶液の苦味
の判定は、水10mlにギムネマ抽出物を溶し、これに所定
量のCDを加えて、2時間攪拌した溶液について5名のパ
ネラーが、ギムネマ抽出物のみの溶液の苦味を10、苦味
を感じないものを0とし、0、2、4、6、8、10の評点
で評価した綜合的判定である。
In the present invention, gymnematic acid extract can be used as a jelly-like product. The production of the jelly-like product may be carried out by a general technique for producing the jelly-like product using gelatin, agar, pectin, alginic acid derivative or the like as a gelling agent, in which case other taste components may be added, and fructose-glucose may be added. Sugar solutions, oligosaccharides, acidulants, sodium citrate, vitamins, orange juice, sweeteners, flavors and the like can be added. The determination of the bitterness of the solution in the following examples was carried out by dissolving Gymnema extract in 10 ml of water, adding a predetermined amount of CD thereto, and stirring the solution for 2 hours by 5 panelists, a solution of Gymnema extract only. The bitterness was evaluated as 10 and the one not feeling bitterness was set as 0, and the comprehensive judgment was evaluated by the scores of 0, 2, 4, 6, 8 and 10.

【0013】参考例 ギムネマ・シルベスタの乾燥葉を60℃の温湯水中で1
0時間浸し水溶性成分の抽出を行った。浸漬液を回転数
1200〜1300rpmにて遠沈させ、その後残渣を除去した上
澄液を凍結乾燥により乾燥し粉末状ギムネマ・シルベス
タ抽出物を得た。さらにこれを水に溶解しpH3に調整し
て遠沈してくる成分を乾燥して粉末状酸性抽出成分を得
た。このギムネマ抽出物100mgに水10mlを加えて、ギム
ネマ抽出物水溶液とし、それぞれにα−、β−またはγ
−CDをそれぞれ100mg加えて包接体を生成させた。こ
の水溶液について官能検査により苦味を判定した。CD
を添加しない溶液の苦味の程度を10とするとき、α−
CD添加では9、β−CD添加では5、γ−CD添加で
は1であった。
Reference Example Dried leaves of Gymnema sylvestre were placed in hot water at 60 ° C. for 1 day.
Soaking for 0 hour was performed to extract water-soluble components. Rotation speed of immersion liquid
After centrifugation at 1200 to 1300 rpm, the supernatant liquid from which the residue was removed was freeze-dried to obtain a powdery Gymnema sylvestre extract. Further, this was dissolved in water, adjusted to pH 3, and the components that had been spun down were dried to obtain a powdery acidic extraction component. To 100 mg of this Gymnema extract, 10 ml of water was added to give a Gymnema extract aqueous solution, and α-, β- or γ was added to each.
-100 mg of each CD was added to generate inclusion bodies. The bitterness of this aqueous solution was determined by a sensory test. CD
When the degree of bitterness of a solution without addition of 10 is α-
It was 9 when CD was added, 5 when β-CD was added, and 1 when γ-CD was added.

【0014】実施例1 参考例で用いたのと同じギムネマ抽出物水溶液を用い
て、γ−CDの添加量を変えて包接体を含む溶液とし
て、官能検査により苦味を判定した。 なお、参考例のギムネマ抽出物に代えて、酸析前の粉末
状ギムネマ・シルベスタ抽出物の同濃度の溶液にγ−C
D300mgを添加した場合には1程度の苦味があった。
Example 1 The same Gymnema extract aqueous solution as that used in the reference example was used, and the bitterness was judged by a sensory test as a solution containing clathrate by changing the addition amount of γ-CD. In place of the Gymnema extract of Reference Example, γ-C was added to a solution of the same concentration of powdered Gymnema sylvestre extract before acid precipitation.
When D300 mg was added, there was a bitterness of about 1.

【0015】実施例2 参考例で用いたのと同じギムネマ抽出物500gを水500ml
を加えた水溶液にγ−CD1500gを加えて包接体を含む
生成させた。これを濃縮乾固して包接体を固体として得
た。この包接体1500gをチャンバーに仕込み、減圧下包
接体を流動させながら水420gをスプレーし、この間、下
部から100℃の熱風を送付する通常の顆粒化技術により
の顆粒とした。この顆粒はそのまま舐めても苦味を感じ
なかった。
Example 2 500 g of the same Gymnema extract as used in the reference example was added to 500 ml of water.
[Gamma] -CD (1500 g) was added to the aqueous solution to which was added to produce an inclusion body. This was concentrated to dryness to obtain a clathrate as a solid. 1500 g of this clathrate was charged into a chamber, 420 g of water was sprayed while flowing the clathrate under reduced pressure, and during this period, granules were formed by a normal granulation technique in which hot air of 100 ° C. was sent from the bottom. The granules did not feel bitter when licked as they were.

【0016】実施例3 実施例2得た包接体顆粒を通常の包装技術により1〜1
0g含むスティック状包装体とした。
Example 3 Example 2 The clathrate granules obtained in Example 2 were used in a conventional packaging technique to give 1-1.
A stick-shaped package containing 0 g was prepared.

【0017】実施例4 実施例3と同様にして得た包接体固体を得た。この包接
体を通常の寒天ゼリーの製造技術によりゼリー製品とし
た。
Example 4 A clathrate solid was obtained in the same manner as in Example 3. This clathrate was made into a jelly product by the usual agar jelly manufacturing technique.

【0018】[0018]

【発明の効果】本発明によれば、γ−CDを用いて包接
体とすることにより、種々の生理活性をもつギムネマ・
シルベスタ抽出物を、苦味を感じることなく、家庭で個
人的に摂取することができ、ギムネマ・シルベスタの有
する生理活性を利用することが可能となる。
INDUSTRIAL APPLICABILITY According to the present invention, a gymnema having various physiological activities can be obtained by forming an inclusion body using γ-CD.
The Sylvestre extract can be ingested personally at home without feeling bitterness, and the physiological activity of Gymnema sylvestre can be utilized.

───────────────────────────────────────────────────── フロントページの続き Fターム(参考) 4C076 AA31 AA36 BB01 CC21 EE39T FF52 4C088 AB12 AC05 BA09 CA05 CA23 MA43 MA52 NA09 ZA70    ─────────────────────────────────────────────────── ─── Continued front page    F term (reference) 4C076 AA31 AA36 BB01 CC21 EE39T                       FF52                 4C088 AB12 AC05 BA09 CA05 CA23                       MA43 MA52 NA09 ZA70

Claims (5)

【特許請求の範囲】[Claims] 【請求項1】ギムネマ・シルベスタ抽出物(固形分)重
量の2倍重量以上のγ−シクロデキストリンを用いて包
接してなるギムネマ・シルベスタ抽出物を含む組成物。
1. A composition comprising a Gymnema sylvestre extract which is clathrated with γ-cyclodextrin in an amount of at least twice the weight of the Gymnema sylvestre extract (solid content).
【請求項2】ギムネマ・シルベスタ抽出物が、ギムネマ
・シルベスタの溶媒抽出物をさらに水中で酸析処理して
得られるギムネマ・シルベスタ抽出物である請求項1に
記載の組成物。
2. The composition according to claim 1, wherein the Gymnema sylvestre extract is a Gymnema sylvester extract obtained by further subjecting a solvent extract of Gymnema sylvestre to acid precipitation in water.
【請求項3】γ−シクロデキストリンがギムネマ・シル
ベスタ抽出物(固形分)重量の2〜5倍重量である請求
項1または2に記載の組成物。
3. The composition according to claim 1, wherein the γ-cyclodextrin is 2 to 5 times the weight of Gymnema sylvestre extract (solid content).
【請求項4】顆粒状である請求項1ないし3のいずれか
に記載の組成物。
4. The composition according to claim 1, which is in the form of granules.
【請求項5】ゼリー状である請求項1ないし3のいずれ
かに記載の組成物。
5. The composition according to claim 1, which is in the form of jelly.
JP2001292333A 2001-09-25 2001-09-25 Composition containing gymnema sylvestre extract and having reduced bitterness Pending JP2003095986A (en)

Priority Applications (1)

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Publication Number Publication Date
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010209029A (en) * 2009-03-12 2010-09-24 Nagase Iyakuhin Kk Pharmaceutical composition or health food with improved taste
JP2016165248A (en) * 2015-03-10 2016-09-15 株式会社ファンケル Tablet for diet

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63105661A (en) * 1986-10-23 1988-05-10 Meiji Seito Kk Drink containing extract of 'shikoutou'
JPH03112932A (en) * 1989-09-27 1991-05-14 Nitto Denko Corp Saccharide absorption inhibitory beverage
JPH0411865A (en) * 1990-04-27 1992-01-16 Meiji Seito Kk Food additive
JPH06343421A (en) * 1993-06-08 1994-12-20 Yasutake Hichi High fat food having antiobestic function
JPH07255390A (en) * 1994-03-16 1995-10-09 Saken Foods:Kk Gymnema jelly
WO1999006028A1 (en) * 1997-07-31 1999-02-11 Vegetalys Corp Method for preparing an extract of active principles in the form of microgranules based on dietary fibres

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63105661A (en) * 1986-10-23 1988-05-10 Meiji Seito Kk Drink containing extract of 'shikoutou'
JPH03112932A (en) * 1989-09-27 1991-05-14 Nitto Denko Corp Saccharide absorption inhibitory beverage
JPH0411865A (en) * 1990-04-27 1992-01-16 Meiji Seito Kk Food additive
JPH06343421A (en) * 1993-06-08 1994-12-20 Yasutake Hichi High fat food having antiobestic function
JPH07255390A (en) * 1994-03-16 1995-10-09 Saken Foods:Kk Gymnema jelly
WO1999006028A1 (en) * 1997-07-31 1999-02-11 Vegetalys Corp Method for preparing an extract of active principles in the form of microgranules based on dietary fibres

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010209029A (en) * 2009-03-12 2010-09-24 Nagase Iyakuhin Kk Pharmaceutical composition or health food with improved taste
JP2016165248A (en) * 2015-03-10 2016-09-15 株式会社ファンケル Tablet for diet

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