JP2002523514A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002523514A5 JP2002523514A5 JP2000567539A JP2000567539A JP2002523514A5 JP 2002523514 A5 JP2002523514 A5 JP 2002523514A5 JP 2000567539 A JP2000567539 A JP 2000567539A JP 2000567539 A JP2000567539 A JP 2000567539A JP 2002523514 A5 JP2002523514 A5 JP 2002523514A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9831398P | 1998-08-27 | 1998-08-27 | |
US60/098,313 | 1998-08-27 | ||
US12974399P | 1999-04-16 | 1999-04-16 | |
US60/129,743 | 1999-04-16 | ||
US14446199P | 1999-07-19 | 1999-07-19 | |
US60/144,461 | 1999-07-19 | ||
PCT/US1999/019838 WO2000012517A1 (en) | 1998-08-27 | 1999-08-27 | Novel hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009035788A Division JP2009143955A (ja) | 1998-08-27 | 2009-02-18 | アレンドロネートナトリウムの新規水和物型、その製造方法、及びその医薬組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2002523514A JP2002523514A (ja) | 2002-07-30 |
JP2002523514A5 true JP2002523514A5 (ja) | 2005-12-22 |
Family
ID=27378576
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000567539A Withdrawn JP2002523514A (ja) | 1998-08-27 | 1999-08-27 | アレンドロネートナトリウムの新規水和物型、その製造方法、及びその医薬組成物 |
JP2009035788A Pending JP2009143955A (ja) | 1998-08-27 | 2009-02-18 | アレンドロネートナトリウムの新規水和物型、その製造方法、及びその医薬組成物 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009035788A Pending JP2009143955A (ja) | 1998-08-27 | 2009-02-18 | アレンドロネートナトリウムの新規水和物型、その製造方法、及びその医薬組成物 |
Country Status (30)
Country | Link |
---|---|
US (2) | US6281381B1 (ja) |
EP (1) | EP1107974B1 (ja) |
JP (2) | JP2002523514A (ja) |
KR (2) | KR20070034132A (ja) |
AT (1) | ATE334993T1 (ja) |
AU (1) | AU5698899A (ja) |
BG (1) | BG65329B1 (ja) |
BR (1) | BR9913472A (ja) |
CA (1) | CA2341459A1 (ja) |
CZ (1) | CZ2001629A3 (ja) |
DE (1) | DE69932620T2 (ja) |
DK (1) | DK1107974T3 (ja) |
EA (1) | EA002739B1 (ja) |
EE (1) | EE04552B1 (ja) |
ES (1) | ES2270613T3 (ja) |
HR (1) | HRP20010129A2 (ja) |
HU (1) | HUP0203078A3 (ja) |
IL (1) | IL141423A (ja) |
IS (1) | IS5864A (ja) |
LT (1) | LT4888B (ja) |
LV (1) | LV12720B (ja) |
NO (1) | NO20010957L (ja) |
NZ (1) | NZ510682A (ja) |
PL (1) | PL346347A1 (ja) |
PT (1) | PT1107974E (ja) |
RO (1) | RO122854B1 (ja) |
SI (1) | SI20581B (ja) |
SK (1) | SK2482001A3 (ja) |
WO (1) | WO2000012517A1 (ja) |
YU (1) | YU14701A (ja) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60235085D1 (de) * | 2001-07-16 | 2010-03-04 | Univ Paris Xiii | Herstellungsverfahren von derivate von bisphosphonaten |
GB2383042A (en) * | 2001-10-18 | 2003-06-18 | Cipla Ltd | Amorphous alendronate sodium |
BR0215413A (pt) * | 2001-12-24 | 2004-12-14 | Teva Pharma | Formula dosada com um comprimido central de ingrediente ativo encapado em uma capa anular prensada de material em pó ou granulado e processo e conjunto de ferramentas para a sua produção |
US20040052843A1 (en) * | 2001-12-24 | 2004-03-18 | Lerner E. Itzhak | Controlled release dosage forms |
ITMI20020146A1 (it) * | 2002-01-29 | 2003-07-29 | Lyogen Ltd | Alendronato monosodico amorfo e processo per la sua preparazione |
AU2003226148A1 (en) * | 2002-04-05 | 2003-10-27 | Merck & Co., Inc. | Method for inhibiting bone resorption with an alendronate and vitamin d formulation |
US20080249068A1 (en) * | 2002-09-05 | 2008-10-09 | Deluca Hector F | Method of Extending the Dose Range of Vitamin D Compounds |
US20050113343A1 (en) * | 2003-10-14 | 2005-05-26 | Pliva - Research And Development Ltd. | Solid-state form of alendronate sodium and preparation thereof |
US20050181043A1 (en) * | 2004-02-12 | 2005-08-18 | Indranil Nandi | Alendronate salt tablet compositions |
US20050261250A1 (en) * | 2004-05-19 | 2005-11-24 | Merck & Co., Inc., | Compositions and methods for inhibiting bone resorption |
WO2005115331A2 (en) | 2004-05-24 | 2005-12-08 | The Procter & Gamble Company | Enteric solid oral dosage form of bisphosphonate containing a chelating agent |
CZ296937B6 (cs) * | 2004-09-02 | 2006-07-12 | Zentiva, A. S | Trisodná sul kyseliny 4-amino-1-hydroxybutyliden-1,1-bisfosfonové |
AR052321A1 (es) * | 2004-10-29 | 2007-03-14 | Sandoz Ag | Procesos para la preparacion de un polipeptido |
US20060134190A1 (en) * | 2004-12-16 | 2006-06-22 | Banner Pharmacaps Inc. | Formulations of bisphosphonate drugs with improved bioavailability |
CZ297262B6 (cs) * | 2004-12-28 | 2006-10-11 | Zentiva, A. S. | Trisodná sul kyseliny 4-amino-1-hydroxybutyliden-1,1-bisfosfonové |
US8003820B2 (en) * | 2005-10-20 | 2011-08-23 | Dr. Reddy's Laboratories Limited | Process for preparing bisphosphonic acids |
AR058168A1 (es) * | 2005-11-07 | 2008-01-23 | Merck & Co Inc | Sintesis del alendronato de sodio trihidratado |
MX2009003913A (es) * | 2006-10-27 | 2009-04-24 | Signal Pharm Llc | Formas solidas que comprenden 4-[9-(tetrahidro-furano-3-il)-8-(2,4 ,6-trifluoro-fenilamino)-9h-purin-2-ilamino]-ciclohexan-1-ol, composiciones de las mismas, y su uso. |
JP5244608B2 (ja) * | 2006-11-22 | 2013-07-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 二糖類化合物のナトリウム塩及びその製造方法並びにその使用 |
US20090118238A1 (en) * | 2007-09-17 | 2009-05-07 | Protia, Llc | Deuterium-enriched alendronate |
US20090076144A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched bazedoxifene |
US20090170815A1 (en) * | 2007-12-28 | 2009-07-02 | Roxane Laboratories Incorporated. | Alendronate oral liquid formulations |
CN102040644B (zh) * | 2009-11-03 | 2014-05-14 | 刘力 | 丹参酮衍生物及其制备和用途 |
RU2021125455A (ru) | 2013-11-15 | 2021-10-05 | Экебиа Терапьютикс, Инк. | Твердые формы { [5-(3-хлорфенил)-3-гидроксипиридин-2-карбонил]амино} уксусной кислоты, их композиции и применения |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3016289A1 (de) | 1980-04-28 | 1981-10-29 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren |
IT1201087B (it) | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
US4639338A (en) * | 1984-08-06 | 1987-01-27 | Ciba-Geigy Corporation | Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate |
DE3434667A1 (de) | 1984-09-21 | 1986-04-03 | Henkel KGaA, 4000 Düsseldorf | 4-dimethylamino-1-hydroxybutan-1,1-diphosphonsaeure, deren wasserloesliche salze, verfahren zu ihrer herstellung sowie ihre verwendung |
IT1196315B (it) * | 1984-10-29 | 1988-11-16 | Gentili Ist Spa | Procedimento per la preparazione di acidi difosfonici |
US4711800A (en) * | 1985-06-06 | 1987-12-08 | Divincenzo Maureen | Needlecraft with metallic substrate |
US4922007A (en) * | 1989-06-09 | 1990-05-01 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof |
US5019651A (en) * | 1990-06-20 | 1991-05-28 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof |
US5039819A (en) | 1990-09-18 | 1991-08-13 | Merck & Co., Inc. | Diphosphonate intermediate for preparing an antihypercalcemic agent |
US5159108A (en) * | 1990-09-18 | 1992-10-27 | Merck & Co., Inc. | Process for preparing an antihypercalcemic agent |
AU6148396A (en) * | 1995-06-06 | 1996-12-24 | Merck & Co., Inc. | Disodium alendronate formulations |
DE69634357T2 (de) * | 1995-06-06 | 2006-01-12 | Merck & Co., Inc. | Formulierungen mit dem wasserfreien mononatriumsalz von alendronat und deren verwendung zur behandlung von knochenkrankheiten |
-
1999
- 1999-08-27 PT PT99944004T patent/PT1107974E/pt unknown
- 1999-08-27 BR BR9913472-1A patent/BR9913472A/pt not_active Application Discontinuation
- 1999-08-27 AT AT99944004T patent/ATE334993T1/de not_active IP Right Cessation
- 1999-08-27 ES ES99944004T patent/ES2270613T3/es not_active Expired - Lifetime
- 1999-08-27 SK SK248-2001A patent/SK2482001A3/sk unknown
- 1999-08-27 EA EA200100184A patent/EA002739B1/ru not_active IP Right Cessation
- 1999-08-27 DE DE69932620T patent/DE69932620T2/de not_active Expired - Fee Related
- 1999-08-27 SI SI9920070A patent/SI20581B/sl not_active IP Right Cessation
- 1999-08-27 NZ NZ510682A patent/NZ510682A/en not_active IP Right Cessation
- 1999-08-27 RO ROA200100219A patent/RO122854B1/ro unknown
- 1999-08-27 KR KR1020077004456A patent/KR20070034132A/ko not_active Application Discontinuation
- 1999-08-27 KR KR1020017002535A patent/KR20010079701A/ko active Search and Examination
- 1999-08-27 DK DK99944004T patent/DK1107974T3/da active
- 1999-08-27 IL IL14142399A patent/IL141423A/xx not_active IP Right Cessation
- 1999-08-27 US US09/384,145 patent/US6281381B1/en not_active Expired - Fee Related
- 1999-08-27 PL PL99346347A patent/PL346347A1/xx not_active Application Discontinuation
- 1999-08-27 HU HU0203078A patent/HUP0203078A3/hu unknown
- 1999-08-27 EE EEP200100126A patent/EE04552B1/xx not_active IP Right Cessation
- 1999-08-27 YU YU14701A patent/YU14701A/sh unknown
- 1999-08-27 WO PCT/US1999/019838 patent/WO2000012517A1/en not_active Application Discontinuation
- 1999-08-27 CZ CZ2001629A patent/CZ2001629A3/cs unknown
- 1999-08-27 EP EP99944004A patent/EP1107974B1/en not_active Expired - Lifetime
- 1999-08-27 JP JP2000567539A patent/JP2002523514A/ja not_active Withdrawn
- 1999-08-27 AU AU56988/99A patent/AU5698899A/en not_active Abandoned
- 1999-08-27 CA CA002341459A patent/CA2341459A1/en not_active Abandoned
-
2001
- 2001-02-22 HR HR20010129A patent/HRP20010129A2/hr not_active Application Discontinuation
- 2001-02-26 LT LT2001016A patent/LT4888B/lt not_active IP Right Cessation
- 2001-02-26 NO NO20010957A patent/NO20010957L/no not_active Application Discontinuation
- 2001-02-26 IS IS5864A patent/IS5864A/is unknown
- 2001-02-26 BG BG105292A patent/BG65329B1/bg unknown
- 2001-04-05 LV LVP-01-26A patent/LV12720B/en unknown
- 2001-07-03 US US09/898,756 patent/US6696601B2/en not_active Expired - Fee Related
-
2009
- 2009-02-18 JP JP2009035788A patent/JP2009143955A/ja active Pending