ITMI20020146A1 - Alendronato monosodico amorfo e processo per la sua preparazione - Google Patents
Alendronato monosodico amorfo e processo per la sua preparazioneInfo
- Publication number
- ITMI20020146A1 ITMI20020146A1 IT2002MI000146A ITMI20020146A ITMI20020146A1 IT MI20020146 A1 ITMI20020146 A1 IT MI20020146A1 IT 2002MI000146 A IT2002MI000146 A IT 2002MI000146A IT MI20020146 A ITMI20020146 A IT MI20020146A IT MI20020146 A1 ITMI20020146 A1 IT MI20020146A1
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- monosodium alendronate
- amorphous monosodium
- amorphous
- alendronate
- Prior art date
Links
- CAKRAHQRJGUPIG-UHFFFAOYSA-M sodium;[4-azaniumyl-1-hydroxy-1-[hydroxy(oxido)phosphoryl]butyl]-hydroxyphosphinate Chemical compound [Na+].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O CAKRAHQRJGUPIG-UHFFFAOYSA-M 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000146A ITMI20020146A1 (it) | 2002-01-29 | 2002-01-29 | Alendronato monosodico amorfo e processo per la sua preparazione |
PCT/EP2002/007066 WO2003064438A1 (en) | 2002-01-29 | 2002-06-26 | Amorphous monosodium alendronate and preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000146A ITMI20020146A1 (it) | 2002-01-29 | 2002-01-29 | Alendronato monosodico amorfo e processo per la sua preparazione |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20020146A0 ITMI20020146A0 (it) | 2002-01-29 |
ITMI20020146A1 true ITMI20020146A1 (it) | 2003-07-29 |
Family
ID=11449012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2002MI000146A ITMI20020146A1 (it) | 2002-01-29 | 2002-01-29 | Alendronato monosodico amorfo e processo per la sua preparazione |
Country Status (2)
Country | Link |
---|---|
IT (1) | ITMI20020146A1 (it) |
WO (1) | WO2003064438A1 (it) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2172192A1 (en) | 2001-12-24 | 2010-04-07 | Teva Pharmaceutical Industries Ltd. | Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder of granular material, and process and tooling for producing it |
CZ297262B6 (cs) * | 2004-12-28 | 2006-10-11 | Zentiva, A. S. | Trisodná sul kyseliny 4-amino-1-hydroxybutyliden-1,1-bisfosfonové |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4922007A (en) * | 1989-06-09 | 1990-05-01 | Merck & Co., Inc. | Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof |
DK0833643T3 (da) * | 1995-06-06 | 2005-05-30 | Merck & Co Inc | Formuleringer af vandfrit mononatriumsalt af alendronat og deres anvendelse til behandling af knoglesygdomme |
IL141423A (en) * | 1998-08-27 | 2005-09-25 | Teva Pharma | Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof |
WO2000034293A1 (en) * | 1998-12-10 | 2000-06-15 | Aesgen, Inc. | Method for preparation of disodium pamidronate |
GB2383042A (en) * | 2001-10-18 | 2003-06-18 | Cipla Ltd | Amorphous alendronate sodium |
-
2002
- 2002-01-29 IT IT2002MI000146A patent/ITMI20020146A1/it unknown
- 2002-06-26 WO PCT/EP2002/007066 patent/WO2003064438A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ITMI20020146A0 (it) | 2002-01-29 |
WO2003064438A1 (en) | 2003-08-07 |
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