ITMI912222A0 - 13-biidro-3'-(2-alcossi-4-morfolinil)antracicline - Google Patents

13-biidro-3'-(2-alcossi-4-morfolinil)antracicline

Info

Publication number
ITMI912222A0
ITMI912222A0 IT91MI2222A ITMI912222A ITMI912222A0 IT MI912222 A0 ITMI912222 A0 IT MI912222A0 IT 91MI2222 A IT91MI2222 A IT 91MI2222A IT MI912222 A ITMI912222 A IT MI912222A IT MI912222 A0 ITMI912222 A0 IT MI912222A0
Authority
IT
Italy
Prior art keywords
morpholylin
bihydro
anthracycline
alkoxy
Prior art date
Application number
IT91MI2222A
Other languages
English (en)
Inventor
Alberto Bargiotti
Daniela Falardi
Antonino Suarato
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ITMI912222A0 publication Critical patent/ITMI912222A0/it
Publication of ITMI912222A1 publication Critical patent/ITMI912222A1/it
Application granted granted Critical
Publication of IT1251158B publication Critical patent/IT1251158B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ITMI912222A 1990-09-12 1991-08-07 13-diidro-3'-(2-alcossi-4-morfolinil)antracicline IT1251158B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909019933A GB9019933D0 (en) 1990-09-12 1990-09-12 13-dihydro-3'-(2-alkoxy-4-morphlinyl)anthracyclines

Publications (3)

Publication Number Publication Date
ITMI912222A0 true ITMI912222A0 (it) 1991-08-07
ITMI912222A1 ITMI912222A1 (it) 1992-03-13
IT1251158B IT1251158B (it) 1995-05-04

Family

ID=10682082

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI912222A IT1251158B (it) 1990-09-12 1991-08-07 13-diidro-3'-(2-alcossi-4-morfolinil)antracicline

Country Status (4)

Country Link
JP (1) JP3068258B2 (it)
DE (1) DE4126475B4 (it)
GB (2) GB9019933D0 (it)
IT (1) IT1251158B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8742076B2 (en) 2008-02-01 2014-06-03 Genentech, Inc. Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
ES2532635T3 (es) 2008-07-15 2015-03-30 Genentech, Inc. Conjugados de antraciclina, proceso para su preparación y su uso como compuestos antitumorales
EP2646456B1 (en) 2010-12-02 2015-01-21 Nerviano Medical Sciences S.r.l. Process for the preparation of morpholinyl anthracycline derivatives
CN105164138B (zh) * 2013-04-29 2017-11-07 内尔维阿诺医学科学有限公司 新吗啉基蒽环类抗生素衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
GB8905668D0 (en) * 1989-03-13 1989-04-26 Erba Carlo Spa New 3'-(4-morpholinyl)-and 3'-(2-methoxy-4-morpholinyl)-anthracycline derivatives

Also Published As

Publication number Publication date
GB2247885A (en) 1992-03-18
GB9019933D0 (en) 1990-10-24
JPH04247096A (ja) 1992-09-03
DE4126475A1 (de) 1992-03-19
ITMI912222A1 (it) 1992-03-13
GB9117175D0 (en) 1991-09-25
DE4126475B4 (de) 2005-09-15
IT1251158B (it) 1995-05-04
JP3068258B2 (ja) 2000-07-24
GB2247885B (en) 1994-02-09

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970728