IT8167177A0 - 2 AMINO 3 HYDROXY PHENYL ME TEL PHENYLACETIC ACIDS THEIR ESTERS AND AMIDES PARTICULARLY USEFUL AS ANTI-INFLAMMATORS - Google Patents
2 AMINO 3 HYDROXY PHENYL ME TEL PHENYLACETIC ACIDS THEIR ESTERS AND AMIDES PARTICULARLY USEFUL AS ANTI-INFLAMMATORSInfo
- Publication number
- IT8167177A0 IT8167177A0 IT8167177A IT6717781A IT8167177A0 IT 8167177 A0 IT8167177 A0 IT 8167177A0 IT 8167177 A IT8167177 A IT 8167177A IT 6717781 A IT6717781 A IT 6717781A IT 8167177 A0 IT8167177 A0 IT 8167177A0
- Authority
- IT
- Italy
- Prior art keywords
- inflammators
- tel
- esters
- amino
- particularly useful
- Prior art date
Links
- GOJUJUVQIVIZAV-UHFFFAOYSA-N 2-amino-4,6-dichloropyrimidine-5-carbaldehyde Chemical compound NC1=NC(Cl)=C(C=O)C(Cl)=N1 GOJUJUVQIVIZAV-UHFFFAOYSA-N 0.000 title 1
- -1 TEL PHENYLACETIC ACIDS Chemical class 0.000 title 1
- 150000001408 amides Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12254480A | 1980-02-19 | 1980-02-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8167177A0 true IT8167177A0 (en) | 1981-02-09 |
IT1146744B IT1146744B (en) | 1986-11-19 |
Family
ID=22403319
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT67177/81A IT1146744B (en) | 1980-02-19 | 1981-02-09 | ACIDS 2 AMINO 3 HYDROXY PHENYL METHYL PHENYLACETICS THEIR ESTERS AND STARCHES PARTICULARLY USEFUL AS ANTI-INFLAMMATORY |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS56131552A (en) |
AU (1) | AU538240B2 (en) |
BE (1) | BE887566A (en) |
CA (1) | CA1156655A (en) |
CH (1) | CH648283A5 (en) |
DE (1) | DE3105285A1 (en) |
FR (1) | FR2476071A1 (en) |
GB (1) | GB2071086B (en) |
IL (1) | IL61945A (en) |
IT (1) | IT1146744B (en) |
NL (1) | NL8100808A (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA805476B (en) * | 1979-09-26 | 1981-11-25 | Robins Co Inc A H | 2-amino-3-benzoyl-phenylacetamides and cyclic homologues |
IL64724A0 (en) * | 1981-02-17 | 1982-03-31 | Robins Co Inc A H | 2-amino-3-(halobenzoyl)-methylphenylacetic acids and esters and salts thereof and pharmaceutical compositions containing them |
US5475034A (en) * | 1994-06-06 | 1995-12-12 | Alcon Laboratories, Inc. | Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders |
AR030345A1 (en) * | 2000-08-14 | 2003-08-20 | Alcon Inc | METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS |
AR030346A1 (en) * | 2000-08-14 | 2003-08-20 | Alcon Inc | METHOD OF TREATMENT OF NEURODEGENERATIVE DISORDERS OF THE RETINA AND HEAD OF OPTICAL NERVE |
AU2002247284A1 (en) | 2001-04-02 | 2002-10-15 | Alcon, Inc. | Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac |
TWI358290B (en) | 2004-12-02 | 2012-02-21 | Alcon Inc | Topical nepafenac formulations |
EP2389355A1 (en) * | 2009-03-12 | 2011-11-30 | Medichem, S.A. | New crystals of a benzoylbenzeneacetamide derivative |
EP2389354A1 (en) * | 2009-04-06 | 2011-11-30 | Medichem, S.A. | 2-{2-amino-3-ýhydroxy(phenyl)methyl¨phenyl} acetamide |
CN106631881B (en) * | 2016-09-08 | 2018-09-21 | 南京工业大学 | 2- (3-benzyl-2- (dimethylamino) phenyl) acetamide and its synthesis method and use |
CN112794809B (en) * | 2019-11-14 | 2023-12-29 | 南京济群医药科技股份有限公司 | Preparation method of high-purity nepafenac intermediate |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE400966B (en) * | 1975-08-13 | 1978-04-17 | Robins Co Inc A H | PROCEDURE FOR PREPARING 2-AMINO-3- (OR 5-) BENZOYL-PHENYLETIC ACIDS |
FR2366015A1 (en) * | 1975-11-05 | 1978-04-28 | Robins Co Inc A H | Amino-benzoyl-phenylacetic acid derivs - antiinflammatory, hypocholesterolemic and blood platelet agglomeration inhibitory activity |
ZA805476B (en) * | 1979-09-26 | 1981-11-25 | Robins Co Inc A H | 2-amino-3-benzoyl-phenylacetamides and cyclic homologues |
-
1981
- 1981-01-20 IL IL61945A patent/IL61945A/en unknown
- 1981-02-09 IT IT67177/81A patent/IT1146744B/en active
- 1981-02-13 DE DE19813105285 patent/DE3105285A1/en not_active Withdrawn
- 1981-02-16 AU AU67330/81A patent/AU538240B2/en not_active Ceased
- 1981-02-18 NL NL8100808A patent/NL8100808A/en not_active Application Discontinuation
- 1981-02-18 CH CH1076/81A patent/CH648283A5/en not_active IP Right Cessation
- 1981-02-18 GB GB8105091A patent/GB2071086B/en not_active Expired
- 1981-02-18 BE BE0/203830A patent/BE887566A/en not_active IP Right Cessation
- 1981-02-18 FR FR8103188A patent/FR2476071A1/en active Granted
- 1981-02-18 CA CA000371185A patent/CA1156655A/en not_active Expired
- 1981-02-19 JP JP2363881A patent/JPS56131552A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
IT1146744B (en) | 1986-11-19 |
JPS56131552A (en) | 1981-10-15 |
FR2476071A1 (en) | 1981-08-21 |
CA1156655A (en) | 1983-11-08 |
DE3105285A1 (en) | 1982-01-21 |
IL61945A (en) | 1984-09-30 |
AU538240B2 (en) | 1984-08-02 |
NL8100808A (en) | 1981-09-16 |
GB2071086A (en) | 1981-09-16 |
FR2476071B1 (en) | 1984-05-11 |
BE887566A (en) | 1981-06-15 |
AU6733081A (en) | 1981-08-27 |
GB2071086B (en) | 1984-02-08 |
IL61945A0 (en) | 1981-02-27 |
JPH0153266B2 (en) | 1989-11-13 |
CH648283A5 (en) | 1985-03-15 |
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