IT7928304A0 - Derivati delle aldeidi della peptidil-arginina e procedimento per la loro preparazione. - Google Patents

Derivati delle aldeidi della peptidil-arginina e procedimento per la loro preparazione.

Info

Publication number: IT7928304A0
Authority: IT; Italy
Prior art keywords: peptidyl; derivatives; procedure; preparation; arginine aldehydes
Prior art date: 1979-01-04

Application number

IT7928304A

Other languages

English (en)

Other versions

IT1166917B (it

Inventor

Bajusz Sandor

Szell Hasenohrl Erszebet

Barabas Eva

Bagdy Daniel

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-01-04

Filing date

1979-12-21

Publication date

1979-12-21

1979-12-21 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1979-12-21 Publication of IT7928304A0 publication Critical patent/IT7928304A0/it

1987-05-06 Application granted granted Critical

1987-05-06 Publication of IT1166917B publication Critical patent/IT1166917B/it

Links

239000004475 Arginine Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Pyrrole Compounds (AREA)

IT28304/79A 1979-01-04 1979-12-21 Derivati delle aldeidi della peptidil-arginina e procediemento per la loro preparazione IT1166917B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU79GO1435A HU177098B (en)	1979-01-04	1979-01-04	Process for producing new peptidyl-n-carboxy-l-arginin-a

Publications (2)

Publication Number	Publication Date
IT7928304A0 true IT7928304A0 (it)	1979-12-21
IT1166917B IT1166917B (it)	1987-05-06

Family

ID=10996883

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT28304/79A IT1166917B (it)	1979-01-04	1979-12-21	Derivati delle aldeidi della peptidil-arginina e procediemento per la loro preparazione

Country Status (20)

Country	Link
US (1)	US4316889A (it)
JP (1)	JPS5951936B2 (it)
AT (1)	AT372076B (it)
AU (1)	AU533343B2 (it)
BE (1)	BE880844A (it)
CA (1)	CA1133897A (it)
CH (1)	CH643820A5 (it)
DE (1)	DE3000225A1 (it)
DK (1)	DK149895C (it)
ES (1)	ES487464A0 (it)
FI (1)	FI67539C (it)
FR (1)	FR2445826A1 (it)
HU (1)	HU177098B (it)
IL (1)	IL58978A (it)
IT (1)	IT1166917B (it)
NL (1)	NL191537C (it)
NO (1)	NO151085C (it)
SE (1)	SE448461B (it)
SU (1)	SU1366062A3 (it)
ZA (1)	ZA796895B (it)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU178398B (en) *	1979-06-12	1982-04-28	Gyogyszerkutato Intezet	Process for producing new agmatine derivatives of activity against haemagglutination
JPS5754157A (en) *	1980-09-19	1982-03-31	Nippon Kayaku Co Ltd	L-argininal derivative and its preparation
HU184368B (en) *	1981-01-13	1984-08-28	Gyogyszerkutato Intezet	Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
DE3481913D1 (de) *	1983-04-27	1990-05-17	Ici America Inc	Prolin-derivate.
HU192646B (en) *	1984-12-21	1987-06-29	Gyogyszerkutato Intezet	Process for preparing new n-alkyl-peptide aldehydes
JPH0312905Y2 (it) *	1984-12-21	1991-03-26
JPH0536046Y2 (it) *	1987-09-09	1993-09-13
ZA897515B (en) *	1988-10-07	1990-06-27	Merrell Dow Pharma	Novel peptidase inhibitors
US5736520A (en) *	1988-10-07	1998-04-07	Merrell Pharmaceuticals Inc.	Peptidase inhibitors
JPH0277227U (it) *	1988-11-30	1990-06-13
US5430023A (en) *	1990-09-28	1995-07-04	Eli Lilly And Company	Tripeptide antithrombotic agents
CA2075154A1 (en) *	1991-08-06	1993-02-07	Neelakantan Balasubramanian	Peptide aldehydes as antithrombotic agents
US5416093A (en) *	1991-11-12	1995-05-16	Eli Lilly And Company	Antithrombotic agents
US5252566A (en) *	1991-11-12	1993-10-12	Eli Lilly And Company	Antithrombotic agents
ATE159030T1 (de) *	1992-03-04	1997-10-15	Gyogyszerkutato Intezet	Neuartige antikoagulierende peptidderivate und arzneimittel die solche enthalten so wie entsprechendes herstellungsverfahren
US5583146A (en) *	1992-12-02	1996-12-10	Bristol-Myers Squibb Company	Heterocyclic thrombin inhibitors
AU675981B2 (en) *	1992-12-02	1997-02-27	Bristol-Myers Squibb Company	Guanidinyl-substituted heterocyclic thrombin inhibitors
IL108031A0 (en) *	1992-12-22	1994-04-12	Procter & Gamble	Difluoro pentapeptide derivatives and pharmaceutical compositions containing them
US5726159A (en) *	1994-03-04	1998-03-10	Eli Lilly And Company	Antithrombotic agents
US5885967A (en) *	1994-03-04	1999-03-23	Eli Lilly And Company	Antithrombotic agents
US5488037A (en) *	1994-03-04	1996-01-30	Eli Lilly And Company	Antithrombotic agents
US5707966A (en) *	1994-03-04	1998-01-13	Eli Lilly And Company	Antithrombotic agents
US5484772A (en) *	1994-03-04	1996-01-16	Eli Lilly And Company	Antithrombotic agents
CA2143533A1 (en) *	1994-03-04	1995-09-05	Kenneth D. Kurz	Antithrombotic agents
US5436229A (en) *	1994-03-04	1995-07-25	Eli Lilly And Company	Bisulfite adducts of arginine aldehydes
ZA951618B (en) *	1994-03-04	1996-08-27	Lilly Co Eli	Antithrombotic agents
US5705487A (en) *	1994-03-04	1998-01-06	Eli Lilly And Company	Antithrombotic agents
US5439888A (en) *	1994-03-04	1995-08-08	Eli Lilly And Company	Antithrombotic agents
US5602101A (en) *	1994-03-04	1997-02-11	Eli Lilly And Company	Antithrombotic agents
US5514777A (en) *	1994-06-17	1996-05-07	Corvas International, Inc.	Methods of synthesis of peptidyl argininals
US5637599A (en) *	1994-06-17	1997-06-10	Corvas International, Inc.	Arginine mimic derivatives as enzyme inhibitors
DE69525641T2 (de) *	1994-06-17	2002-10-17	Corvas International, Inc.	Verfahren zur herstellung von peptidyl-argininaldehyden
US5914319A (en) *	1995-02-27	1999-06-22	Eli Lilly And Company	Antithrombotic agents
US5710130A (en) *	1995-02-27	1998-01-20	Eli Lilly And Company	Antithrombotic agents
US5919765A (en) *	1995-06-07	1999-07-06	Cor Therapeutics, Inc.	Inhibitors of factor XA
US5721214A (en) *	1995-06-07	1998-02-24	Cor Therapeutics, Inc.	Inhibitors of factor Xa
US6022861A (en) *	1995-06-07	2000-02-08	Cor Therapeutics, Inc.	Ketoheterocyclic inhibitors of factor Xa
US6069130A (en) *	1995-06-07	2000-05-30	Cor Therapeutics, Inc.	Ketoheterocyclic inhibitors of factor Xa
US6046169A (en) *	1995-06-07	2000-04-04	Cor Therapeutics, Inc.	Inhibitors of factor XA
DE69631692T2 (de) *	1995-12-29	2004-12-02	3-Dimensional Pharmaceuticals, Inc.	Amidino proteaseinhibitoren
US6245743B1 (en)	1996-06-05	2001-06-12	Cor Therapeutics, Inc.	Inhibitors of factor Xa

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS4941418A (it) *	1972-08-29	1974-04-18
HU169870B (it) *	1974-06-14	1977-02-28

1979
- 1979-01-04 HU HU79GO1435A patent/HU177098B/hu unknown
- 1979-12-17 IL IL58978A patent/IL58978A/xx unknown
- 1979-12-19 ZA ZA00796895A patent/ZA796895B/xx unknown
- 1979-12-21 IT IT28304/79A patent/IT1166917B/it active
- 1979-12-24 BE BE1/9666A patent/BE880844A/fr not_active IP Right Cessation
- 1979-12-26 JP JP54168478A patent/JPS5951936B2/ja not_active Expired
- 1979-12-27 AU AU54207/79A patent/AU533343B2/en not_active Expired
- 1979-12-27 FR FR7931744A patent/FR2445826A1/fr active Granted
- 1979-12-28 NO NO794327A patent/NO151085C/no unknown
- 1979-12-28 US US06/108,224 patent/US4316889A/en not_active Expired - Lifetime
1980
- 1980-01-02 SE SE8000032A patent/SE448461B/sv not_active IP Right Cessation
- 1980-01-02 FI FI800008A patent/FI67539C/fi not_active IP Right Cessation
- 1980-01-02 AT AT0001280A patent/AT372076B/de not_active IP Right Cessation
- 1980-01-03 DK DK3880A patent/DK149895C/da not_active IP Right Cessation
- 1980-01-03 CH CH780A patent/CH643820A5/de not_active IP Right Cessation
- 1980-01-03 SU SU802861956A patent/SU1366062A3/ru active
- 1980-01-04 ES ES487464A patent/ES487464A0/es active Granted
- 1980-01-04 CA CA343,115A patent/CA1133897A/en not_active Expired
- 1980-01-04 DE DE19803000225 patent/DE3000225A1/de active Granted
- 1980-01-04 NL NL8000040A patent/NL191537C/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
CH643820A5 (de)	1984-06-29
FI67539C (fi)	1985-04-10
FI800008A (fi)	1980-07-05
NL191537B (nl)	1995-05-01
AU5420779A (en)	1980-07-10
SE448461B (sv)	1987-02-23
ZA796895B (en)	1980-12-31
SU1366062A3 (ru)	1988-01-07
AU533343B2 (en)	1983-11-17
NO151085C (no)	1985-02-06
ATA1280A (de)	1983-01-15
NO794327L (no)	1980-07-07
CA1133897A (en)	1982-10-19
IT1166917B (it)	1987-05-06
DK149895C (da)	1987-04-21
DK3880A (da)	1980-07-05
FI67539B (fi)	1984-12-31
DE3000225C2 (it)	1989-10-19
DE3000225A1 (de)	1980-07-24
JPS5951936B2 (ja)	1984-12-17
JPS55122749A (en)	1980-09-20
NL8000040A (nl)	1980-07-08
DK149895B (da)	1986-10-20
HU177098B (en)	1981-07-28
AT372076B (de)	1983-08-25
NL191537C (nl)	1995-09-04
IL58978A0 (en)	1980-03-31
FR2445826A1 (fr)	1980-08-01
SE8000032L (sv)	1980-07-05
US4316889A (en)	1982-02-23
FR2445826B1 (it)	1984-11-23
IL58978A (en)	1982-09-30
BE880844A (fr)	1980-06-24
NO151085B (no)	1984-10-29
ES8100252A1 (es)	1980-11-01
ES487464A0 (es)	1980-11-01

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19961230

Publication	Publication Date	Title
IT7928304A0 (it)	1979-12-21	Derivati delle aldeidi della peptidil-arginina e procedimento per la loro preparazione.
IT1160264B (it)	1987-03-11	Derivati della prostaciclina e procedimento per la loro preparazione
IT7925621A0 (it)	1979-09-11	Cefem derivati e procedimento per la loro preparazione.
IT1188970B (it)	1988-01-28	Derivati della moranolina e procedimento per la loro preparazione
IT1075373B (it)	1985-04-22	Derivati della prostaglandina e procedimento per la loro preparazione
IT1102816B (it)	1985-10-07	Derivati amminoalcossifinilici e procedimento per la loro preparazione
IT1192621B (it)	1988-04-27	Derivati della maleinimmide e succinimmide e procedimento per la loro preparazione
IT8024150A0 (it)	1980-08-13	Derivati di alovincamone eprocedimento per la loro preparazione.
IT1147741B (it)	1986-11-26	Derivati di idrossiammino eburnano e procedimento per la loro preparazione
IT1109400B (it)	1985-12-16	Derivati di 2-amminometil-fenolo e procedimento per la loro preparazione
IT7819332A0 (it)	1978-01-17	Derivati solfonilidrazonici eprocedimento per la loro preparazione.
IT7825682A0 (it)	1978-07-14	Derivati dei bis(nitrosoureido)-polioli eprocedimento per la loro preparazione.
IT8320278A0 (it)	1983-03-24	Derivati delle rifamicine eprocedimento per la loro preparazione.
IT7823931A0 (it)	1978-05-29	Derivati della bromexina eprocedimento per la loro preparazione.
IT8024151A0 (it)	1980-08-13	Derivati di 10-alo-e-omoeburnano eprocedimento per la loro preparazione.
IT1212412B (it)	1989-11-22	Derivati della benzo-as-triazina e procedimento per la loro preparazione.
IT8124030A0 (it)	1981-09-18	Derivati della 7-ossoprostaciclina e procedimento per la loro preparazione.
IT1149882B (it)	1986-12-10	Derivati della pirazolo chinazolina e procedimento per la loro preparazione
IT1163698B (it)	1987-04-08	Derivati di 1-ftalazone, procedimento per la loro preparazione, e loro impiego
IT1148812B (it)	1986-12-03	Derivati della fenotiazina, e procedimento per la loro preparazione
IT1063405B (it)	1985-02-11	Derivati di tetradiroisochinolive e procedimento per la loro preparazione
IT1157053B (it)	1987-02-11	Derivati della prolina e procedimento per la loro preparazione
IT7820091A0 (it)	1978-02-09	Derivati delle everninomicine eprocedimento per la loro preparazione.
IT8120276A0 (it)	1981-03-11	Derivati steroidei della spiro-ossatiazolidina eprocedimento per la loro preparazione.
IT7825975A0 (it)	1978-07-21	Derivati di peruvosidi eprocedimento per la loro preparazione.