IT1317042B1 - Fumarati doppi di una carnitina e creatina, e integratori alimentari,dietetici e farmaci che li contengono. - Google Patents

Fumarati doppi di una carnitina e creatina, e integratori alimentari,dietetici e farmaci che li contengono.

Info

Publication number
IT1317042B1
IT1317042B1 IT2000RM000322A ITRM20000322A IT1317042B1 IT 1317042 B1 IT1317042 B1 IT 1317042B1 IT 2000RM000322 A IT2000RM000322 A IT 2000RM000322A IT RM20000322 A ITRM20000322 A IT RM20000322A IT 1317042 B1 IT1317042 B1 IT 1317042B1
Authority
IT
Italy
Prior art keywords
carnitine
drugs
diets
creatine
contain
Prior art date
Application number
IT2000RM000322A
Other languages
English (en)
Inventor
Antonietta Buononato
Original Assignee
Biosalts Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosalts Srl filed Critical Biosalts Srl
Publication of ITRM20000322A0 publication Critical patent/ITRM20000322A0/it
Priority to IT2000RM000322A priority Critical patent/IT1317042B1/it
Priority to PT01934310T priority patent/PT1289931E/pt
Priority to AT01934310T priority patent/ATE286016T1/de
Priority to AU60603/01A priority patent/AU783291B2/en
Priority to ES01934310T priority patent/ES2233635T3/es
Priority to KR1020027016899A priority patent/KR100596732B1/ko
Priority to PCT/IT2001/000199 priority patent/WO2001096281A1/en
Priority to MXPA02012265A priority patent/MXPA02012265A/es
Priority to DK01934310T priority patent/DK1289931T3/da
Priority to CA002412055A priority patent/CA2412055C/en
Priority to DE60108122T priority patent/DE60108122T2/de
Priority to EP01934310A priority patent/EP1289931B1/en
Priority to CZ20023949A priority patent/CZ302371B6/cs
Priority to CNB018111092A priority patent/CN1326832C/zh
Priority to HU0301568A priority patent/HU228837B1/hu
Priority to PL363511A priority patent/PL203876B1/pl
Priority to BR0111579-0A priority patent/BR0111579A/pt
Priority to US10/297,843 priority patent/US6730693B2/en
Priority to JP2002510425A priority patent/JP4430301B2/ja
Publication of ITRM20000322A1 publication Critical patent/ITRM20000322A1/it
Application granted granted Critical
Publication of IT1317042B1 publication Critical patent/IT1317042B1/it
Priority to HK03109000A priority patent/HK1056549A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13Nucleic acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02Monosaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
IT2000RM000322A 2000-06-14 2000-06-14 Fumarati doppi di una carnitina e creatina, e integratori alimentari,dietetici e farmaci che li contengono. IT1317042B1 (it)

Priority Applications (20)

Application Number Priority Date Filing Date Title
IT2000RM000322A IT1317042B1 (it) 2000-06-14 2000-06-14 Fumarati doppi di una carnitina e creatina, e integratori alimentari,dietetici e farmaci che li contengono.
DE60108122T DE60108122T2 (de) 2000-06-14 2001-04-24 Fumarsäuredoppelsalze mit carnitin und einer aminosäure und nahrungs- und lebensmittelzusätze und medikamente die diese enthalten
CZ20023949A CZ302371B6 (cs) 2000-06-14 2001-04-24 Fumarát karnitinu a aminokyseliny a potravinové a dietní doplnky a léciva je obsahující
AU60603/01A AU783291B2 (en) 2000-06-14 2001-04-24 Double salts of fumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same
ES01934310T ES2233635T3 (es) 2000-06-14 2001-04-24 Sales dobles de acido fumarico con una carnitina y un aminoacido y suplementos alimentarios, suplementos dieteticos y farmacos que los contienen.
KR1020027016899A KR100596732B1 (ko) 2000-06-14 2001-04-24 푸마르산과 카르니틴 및 아미노산과의 복염, 및 이를함유하는 건강 보조식품, 식이성 보충식 및 약물
PCT/IT2001/000199 WO2001096281A1 (en) 2000-06-14 2001-04-24 Double salts of fumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same
MXPA02012265A MXPA02012265A (es) 2000-06-14 2001-04-24 Sales dobles de acido fumarico con una carnitina y un aminoacido y suplementos alimenticios, suplementos dieteticos y farmacos que contienen las mismas.
DK01934310T DK1289931T3 (da) 2000-06-14 2001-04-24 Dobbeltsalte af fumarsyre med et carnitin og en aminosyre samt kosttilskud, diættilskud og lægemidler indeholdende samme
CA002412055A CA2412055C (en) 2000-06-14 2001-04-24 Double salts of fumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same
PT01934310T PT1289931E (pt) 2000-06-14 2001-04-24 Sais duplos de acido fumarico com uma carnitina e um aminoacido e suplementos alimentares, suplementos dieteticos e farmacos contendo os mesmos
EP01934310A EP1289931B1 (en) 2000-06-14 2001-04-24 Double salts of fumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same
AT01934310T ATE286016T1 (de) 2000-06-14 2001-04-24 Fumarsäuredoppelsalze mit carnitin und einer aminosäure und nahrungs- und lebensmittelzusätze und medikamente die diese enthalten
CNB018111092A CN1326832C (zh) 2000-06-14 2001-04-24 肉碱和氨基酸的富马酸复盐以及含有该盐的食品添加剂、饮食添加剂和药物
HU0301568A HU228837B1 (en) 2000-06-14 2001-04-24 Double salts of fumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same
PL363511A PL203876B1 (pl) 2000-06-14 2001-04-24 Podwójne sole kwasu fumarowego z karnityną i aminokwasem i zawierające je środki do wzbogacania żywności, dodatki do pożywienia i leki
BR0111579-0A BR0111579A (pt) 2000-06-14 2001-04-24 Sais duplos de ácido fumárico com uma carnitina e um aminoácido e suplementos alimentares, suplementos diéteticos e drogas contendo os mesmos
US10/297,843 US6730693B2 (en) 2000-06-14 2001-04-24 Double salts of fumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same
JP2002510425A JP4430301B2 (ja) 2000-06-14 2001-04-24 フマル酸のカルニチンおよびアミノ酸との複塩ならびにその塩を含有する食品補助剤、栄養補助剤および薬剤
HK03109000A HK1056549A1 (en) 2000-06-14 2003-12-11 Double salts offumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000RM000322A IT1317042B1 (it) 2000-06-14 2000-06-14 Fumarati doppi di una carnitina e creatina, e integratori alimentari,dietetici e farmaci che li contengono.

Publications (3)

Publication Number Publication Date
ITRM20000322A0 ITRM20000322A0 (it) 2000-06-14
ITRM20000322A1 ITRM20000322A1 (it) 2001-12-14
IT1317042B1 true IT1317042B1 (it) 2003-05-26

Family

ID=11454785

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000RM000322A IT1317042B1 (it) 2000-06-14 2000-06-14 Fumarati doppi di una carnitina e creatina, e integratori alimentari,dietetici e farmaci che li contengono.

Country Status (20)

Country Link
US (1) US6730693B2 (it)
EP (1) EP1289931B1 (it)
JP (1) JP4430301B2 (it)
KR (1) KR100596732B1 (it)
CN (1) CN1326832C (it)
AT (1) ATE286016T1 (it)
AU (1) AU783291B2 (it)
BR (1) BR0111579A (it)
CA (1) CA2412055C (it)
CZ (1) CZ302371B6 (it)
DE (1) DE60108122T2 (it)
DK (1) DK1289931T3 (it)
ES (1) ES2233635T3 (it)
HK (1) HK1056549A1 (it)
HU (1) HU228837B1 (it)
IT (1) IT1317042B1 (it)
MX (1) MXPA02012265A (it)
PL (1) PL203876B1 (it)
PT (1) PT1289931E (it)
WO (1) WO2001096281A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140099364A2 (en) 2004-10-08 2014-04-10 Forward Pharma A/S Controlled release pharmaceutical compositions comprising a fumaric acid ester
US20080227847A1 (en) * 2005-07-07 2008-09-18 Aditech Pharma Ab Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use
CN101209975B (zh) * 2006-12-29 2010-12-01 沈阳科硕营养科技有限公司 左旋肉碱富马酸钙及其制备方法与用途
PT2379063E (pt) 2009-01-09 2013-05-03 Forward Pharma As Formulação farmacêutica compreendendo um ou mais ésteres de ácido fumárico numa matriz de erosão
RS57497B1 (sr) 2013-03-14 2018-10-31 Alkermes Pharma Ireland Ltd Prolekovi fumarata i njihova upotreba u lečenju raznih bolesti
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
EP3110793B1 (en) 2014-02-24 2019-08-21 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
FR2635264B1 (fr) 1988-08-12 1992-02-28 Bellon Labor Sa Roger Compositions pharmaceutiques et/ou dietetiques contenant de la l-carnitine et de la l-lysine
IT1245699B (it) * 1991-05-29 1994-10-14 Sigma Tau Ind Farmaceuti Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi
US5994581A (en) * 1998-03-09 1999-11-30 Amt Labs, Inc. Carnitine creatinate

Also Published As

Publication number Publication date
BR0111579A (pt) 2003-03-18
US6730693B2 (en) 2004-05-04
EP1289931B1 (en) 2004-12-29
KR20030017536A (ko) 2003-03-03
CZ20023949A3 (cs) 2003-04-16
KR100596732B1 (ko) 2006-07-04
EP1289931A1 (en) 2003-03-12
DE60108122D1 (de) 2005-02-03
US20030171417A1 (en) 2003-09-11
CN1436166A (zh) 2003-08-13
WO2001096281A1 (en) 2001-12-20
AU6060301A (en) 2001-12-24
HUP0301568A3 (en) 2004-12-28
PL363511A1 (en) 2004-11-29
ATE286016T1 (de) 2005-01-15
CN1326832C (zh) 2007-07-18
ES2233635T3 (es) 2005-06-16
ITRM20000322A1 (it) 2001-12-14
AU783291B2 (en) 2005-10-13
ITRM20000322A0 (it) 2000-06-14
DE60108122T2 (de) 2005-12-29
JP4430301B2 (ja) 2010-03-10
CA2412055C (en) 2009-02-03
HUP0301568A2 (hu) 2003-08-28
CZ302371B6 (cs) 2011-04-13
CA2412055A1 (en) 2001-12-20
HK1056549A1 (en) 2004-02-20
MXPA02012265A (es) 2004-02-27
HU228837B1 (en) 2013-06-28
JP2004503521A (ja) 2004-02-05
PT1289931E (pt) 2005-03-31
PL203876B1 (pl) 2009-11-30
DK1289931T3 (da) 2005-04-25

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