IT1205446B - METABOLIZABLE OR DEGRADABLE STEREOIDS CAPABLE OF EXPLICATING AN ANTI-FLOGISTIC ACTION - Google Patents
METABOLIZABLE OR DEGRADABLE STEREOIDS CAPABLE OF EXPLICATING AN ANTI-FLOGISTIC ACTIONInfo
- Publication number
- IT1205446B IT1205446B IT05186/81A IT518681A IT1205446B IT 1205446 B IT1205446 B IT 1205446B IT 05186/81 A IT05186/81 A IT 05186/81A IT 518681 A IT518681 A IT 518681A IT 1205446 B IT1205446 B IT 1205446B
- Authority
- IT
- Italy
- Prior art keywords
- flogistic
- stereoids
- explicating
- metabolizable
- degradable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16845380A | 1980-07-10 | 1980-07-10 | |
US26578581A | 1981-05-21 | 1981-05-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8105186A0 IT8105186A0 (en) | 1981-07-09 |
IT1205446B true IT1205446B (en) | 1989-03-23 |
Family
ID=26864131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT05186/81A IT1205446B (en) | 1980-07-10 | 1981-07-09 | METABOLIZABLE OR DEGRADABLE STEREOIDS CAPABLE OF EXPLICATING AN ANTI-FLOGISTIC ACTION |
Country Status (17)
Country | Link |
---|---|
KR (2) | KR860000266B1 (en) |
AT (1) | AT379816B (en) |
AU (1) | AU540898B2 (en) |
CA (1) | CA1174667A (en) |
CH (1) | CH648856A5 (en) |
DE (1) | DE3126732C2 (en) |
DK (1) | DK165837C (en) |
ES (2) | ES504340A0 (en) |
FI (1) | FI71748C (en) |
FR (1) | FR2486529A1 (en) |
GB (1) | GB2079755B (en) |
IT (1) | IT1205446B (en) |
NL (1) | NL192343C (en) |
NO (1) | NO163285C (en) |
PH (1) | PH25874A (en) |
PT (1) | PT73348B (en) |
SE (1) | SE449106B (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2137206B (en) * | 1980-02-15 | 1985-04-03 | Glaxo Group Ltd | Androstane 17-carbothioc acid derivatives |
JPS6041607A (en) * | 1983-08-12 | 1985-03-05 | Otsuka Pharmaceut Co Ltd | Ointment base |
SE8501693D0 (en) * | 1985-04-04 | 1985-04-04 | Draco Ab | NOVEL 16,17-ACETALSUBSTITUTED ANDROSTANE-17BETA-CARBOXYLIC ACID ESTERS |
IL78144A0 (en) * | 1985-04-04 | 1986-07-31 | Draco Ab | Novel androstane-17beta-carboxylic acid esters |
ATE90355T1 (en) * | 1987-10-13 | 1993-06-15 | Nicholas S Bodor | SOFT STEROIDS WITH ANTI-INFLAMMATORY EFFECTS. |
DE4025342A1 (en) * | 1990-08-10 | 1992-02-13 | Hoechst Ag | CORTICOID-17-ALKYLCARBONATE SUBSTITUTED IN 17-POSITION, METHOD FOR THE PRODUCTION THEREOF, AND MEDICINAL PRODUCTS CONTAINING THE SAME |
EP0998484B1 (en) * | 1997-06-30 | 2004-03-03 | Glaxo Group Limited | Method of identifying compounds having reduced systemic effects |
AR032471A1 (en) | 2000-08-05 | 2003-11-12 | Glaxo Group Ltd | DERIVED FROM ANDROSTAN AND SOLVATOS OF THE SAME, ITS USE FOR THE MANUFACTURE OF MEDICINES, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM, PROCESSES TO PREPARE SUCH DERIVATIVES, USEFUL INTERMEDIARIES IN THE PREPARATION OF SUCH DERIVATIVES, PROCESSES TO PREPARE SUCH INTERMEDIATES |
US6858596B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
US6759398B2 (en) | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
GB0019172D0 (en) | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
US6750210B2 (en) | 2000-08-05 | 2004-06-15 | Smithkline Beecham Corporation | Formulation containing novel anti-inflammatory androstane derivative |
US6787532B2 (en) | 2000-08-05 | 2004-09-07 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivatives |
US6777399B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6858593B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
US6777400B2 (en) | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
UA77656C2 (en) | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
UA82323C2 (en) * | 2002-08-09 | 2008-04-10 | Меда Фарма Гмбх & Ко. Кг | Novel combination of a glucocorticoid and pde-inhibitor for the treatment of respiratory diseases, allergic diseases, asthma and chronic obstructive pulmonary diseases |
GB0316290D0 (en) | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
JP5281291B2 (en) | 2005-01-10 | 2013-09-04 | グラクソ グループ リミテッド | New compounds |
TWI374147B (en) * | 2006-01-27 | 2012-10-11 | Sun Pharma Advance Res Company Ltd | Novel 11β-hydroxyandrosta-4-ene-3-ones |
US7687484B2 (en) * | 2006-05-25 | 2010-03-30 | Bodor Nicholas S | Transporter enhanced corticosteroid activity |
US7691811B2 (en) * | 2006-05-25 | 2010-04-06 | Bodor Nicholas S | Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye |
CN101942001B (en) * | 2010-08-24 | 2013-02-06 | 山东省医药工业研究所 | Purification method of loteprednol etabonate |
CN103183714A (en) * | 2011-12-29 | 2013-07-03 | 山东方明药业集团股份有限公司 | Synthetic method for loteprednol |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1384372A (en) * | 1971-01-20 | 1975-02-19 | Glaxo Lab Ltd | Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids |
GB1438940A (en) * | 1972-07-19 | 1976-06-09 | Glaxo Lab Ltd | 17beta-haloalkoxycarbonyl-17alpha-oxysteroids |
GB1514476A (en) * | 1974-08-30 | 1978-06-14 | Glaxo Lab Ltd | Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates |
DE2735110A1 (en) * | 1977-08-04 | 1979-02-15 | Hoechst Ag | CORTICOID-17-ALKYLCARBONATE AND METHOD FOR THE PRODUCTION THEREOF |
IT1114534B (en) * | 1978-02-08 | 1986-01-27 | Glaxo Group Ltd | ANTI-INFLAMMATORY STEROID OF THE ANDROSTANE SERIES COMPOSITIONS THAT CONTAIN IT AND PROCEDURE TO PRODUCE IT |
US4188385A (en) * | 1978-04-05 | 1980-02-12 | Syntex (U.S.A.) Inc. | Thioetianic acid derivatives |
DE2817988A1 (en) * | 1978-04-25 | 1979-11-08 | Hoechst Ag | CORTICOID 17-ALKYLCARBONATE AND METHOD FOR THE PRODUCTION THEREOF |
-
1981
- 1981-07-02 SE SE8104132A patent/SE449106B/en not_active IP Right Cessation
- 1981-07-06 AU AU72591/81A patent/AU540898B2/en not_active Expired
- 1981-07-06 GB GB8120864A patent/GB2079755B/en not_active Expired
- 1981-07-07 DE DE3126732A patent/DE3126732C2/en not_active Expired
- 1981-07-08 PH PH25877A patent/PH25874A/en unknown
- 1981-07-08 CH CH4497/81A patent/CH648856A5/en not_active IP Right Cessation
- 1981-07-08 CA CA000381293A patent/CA1174667A/en not_active Expired
- 1981-07-08 DK DK302181A patent/DK165837C/en not_active IP Right Cessation
- 1981-07-09 IT IT05186/81A patent/IT1205446B/en active
- 1981-07-09 FI FI812175A patent/FI71748C/en not_active IP Right Cessation
- 1981-07-09 NO NO812344A patent/NO163285C/en unknown
- 1981-07-10 NL NL8103315A patent/NL192343C/en not_active IP Right Cessation
- 1981-07-10 FR FR8113607A patent/FR2486529A1/en active Granted
- 1981-07-10 AT AT0307081A patent/AT379816B/en not_active IP Right Cessation
- 1981-07-10 PT PT73348A patent/PT73348B/en unknown
- 1981-07-10 ES ES504340A patent/ES504340A0/en active Granted
- 1981-07-10 KR KR1019810002502A patent/KR860000266B1/en active
-
1982
- 1982-08-02 ES ES514633A patent/ES8306767A1/en not_active Expired
-
1984
- 1984-09-25 KR KR1019840005874A patent/KR860000452B1/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970730 |