IT1190405B - Derivati del flavone - Google Patents
Derivati del flavoneInfo
- Publication number
- IT1190405B IT1190405B IT22578/85A IT2257885A IT1190405B IT 1190405 B IT1190405 B IT 1190405B IT 22578/85 A IT22578/85 A IT 22578/85A IT 2257885 A IT2257885 A IT 2257885A IT 1190405 B IT1190405 B IT 1190405B
- Authority
- IT
- Italy
- Prior art keywords
- flavone derivatives
- flavone
- derivatives
- Prior art date
Links
- 150000002212 flavone derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22578/85A IT1190405B (it) | 1985-10-22 | 1985-10-22 | Derivati del flavone |
IL80229A IL80229A0 (en) | 1985-10-22 | 1986-10-03 | Flavone derivatives,their preparation and pharmaceutical compositions containing them |
GR862546A GR862546B (en) | 1985-10-22 | 1986-10-14 | Flavone derivatives |
NO864108A NO167570C (no) | 1985-10-22 | 1986-10-15 | Analogifremgangsmaate for fremstilling av terapeutisk aktive flavonforbindelser. |
AR86305576A AR243883A1 (es) | 1985-10-22 | 1986-10-15 | Procedimiento para preparar nuevos derivados de flavona con actividad antogonica de calcio asi como con actividad relajante de la musculatura lisa. |
NZ217964A NZ217964A (en) | 1985-10-22 | 1986-10-16 | Substituted flavone derivatives and pharmaceutical compositions |
DE8686830300T DE3684244D1 (de) | 1985-10-22 | 1986-10-20 | Flavon-derivate. |
EP86830300A EP0223744B1 (en) | 1985-10-22 | 1986-10-20 | Flavone derivatives |
ZA867941A ZA867941B (en) | 1985-10-22 | 1986-10-20 | Flavone derivatives |
AT86830300T ATE73453T1 (de) | 1985-10-22 | 1986-10-20 | Flavon-derivate. |
ES8602677A ES2002425A6 (es) | 1985-10-22 | 1986-10-20 | Un procedimiento para preparar nuevos derivados de flavona |
JP61251553A JPH0772186B2 (ja) | 1985-10-22 | 1986-10-21 | フラボン誘導体、その製造法及びそれを含む医薬 |
IE276886A IE58330B1 (en) | 1985-10-22 | 1986-10-21 | Flavone derivatives |
FI864260A FI89167C (fi) | 1985-10-22 | 1986-10-21 | Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara flavonyl-1,4-dihydropyridinderivat |
TNTNSN86144A TNSN86144A1 (fr) | 1985-10-22 | 1986-10-21 | Procede pour la preparation de derives de la flavone |
HU864363A HU202863B (en) | 1985-10-22 | 1986-10-21 | Process for producing flavon derivatives |
CA000520953A CA1330994C (en) | 1985-10-22 | 1986-10-21 | Flavone derivatives |
KR1019860008836A KR910009269B1 (ko) | 1985-10-22 | 1986-10-22 | 플라본 유도체의 제조방법 |
CN198686107544A CN86107544A (zh) | 1985-10-22 | 1986-10-22 | 黄酮衍生物的制备方法 |
PT83604A PT83604B (pt) | 1985-10-22 | 1986-10-22 | Processo para a preparacao de derivados da flavona e de composicoes farmaceuticas que os contem |
DK506386A DK169408B1 (da) | 1985-10-22 | 1986-10-22 | Terapeutisk aktive 4-(3-methylflavon-8-yl)-1,4-dihydropyridinderivater, fremgangsnmåder til fremstilling heraf samt farmaceutiske midler indeholdende disse |
EG662/86A EG18109A (en) | 1985-10-22 | 1986-10-22 | Process for preparing flavone derivatives |
PH34400A PH22766A (en) | 1985-10-22 | 1986-10-22 | Therapeutically active flavonyl-1,4-dihydropyridines |
US06/921,397 US4806534A (en) | 1985-10-22 | 1986-10-22 | Therapeutically active flavonyl-1,4-dihydrophyridines |
AU64273/86A AU596382B2 (en) | 1985-10-22 | 1986-10-22 | Flavone derivatives |
SG551/92A SG55192G (en) | 1985-10-22 | 1992-05-23 | Flavone derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22578/85A IT1190405B (it) | 1985-10-22 | 1985-10-22 | Derivati del flavone |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8522578A0 IT8522578A0 (it) | 1985-10-22 |
IT1190405B true IT1190405B (it) | 1988-02-16 |
Family
ID=11198039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22578/85A IT1190405B (it) | 1985-10-22 | 1985-10-22 | Derivati del flavone |
Country Status (26)
Country | Link |
---|---|
US (1) | US4806534A (it) |
EP (1) | EP0223744B1 (it) |
JP (1) | JPH0772186B2 (it) |
KR (1) | KR910009269B1 (it) |
CN (1) | CN86107544A (it) |
AR (1) | AR243883A1 (it) |
AT (1) | ATE73453T1 (it) |
AU (1) | AU596382B2 (it) |
CA (1) | CA1330994C (it) |
DE (1) | DE3684244D1 (it) |
DK (1) | DK169408B1 (it) |
EG (1) | EG18109A (it) |
ES (1) | ES2002425A6 (it) |
FI (1) | FI89167C (it) |
GR (1) | GR862546B (it) |
HU (1) | HU202863B (it) |
IE (1) | IE58330B1 (it) |
IL (1) | IL80229A0 (it) |
IT (1) | IT1190405B (it) |
NO (1) | NO167570C (it) |
NZ (1) | NZ217964A (it) |
PH (1) | PH22766A (it) |
PT (1) | PT83604B (it) |
SG (1) | SG55192G (it) |
TN (1) | TNSN86144A1 (it) |
ZA (1) | ZA867941B (it) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4912223A (en) * | 1988-01-28 | 1990-03-27 | Nelson Research & Development Co. | 1,4-Dihydropyridines |
US5580751A (en) * | 1990-09-14 | 1996-12-03 | Carlsberg A/S | Process for the preparation of C-terminally amidated peptides |
US5244602A (en) * | 1990-12-03 | 1993-09-14 | Ppg Industries, Inc. | Photochromic naphthopyrans |
DE4321030A1 (de) * | 1993-06-24 | 1995-01-05 | Bayer Ag | 4-bicyclisch substituierte Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimittel |
SE9703377D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | New compounds |
KR100392468B1 (ko) * | 2000-09-18 | 2003-07-22 | 주식회사 엘지생명과학 | 사이클린 의존 키나아제의 저해제로서 유용한3-히드록시크로멘-4-온 유도체 |
MXPA03006250A (es) | 2001-01-16 | 2003-09-22 | Astrazeneca Ab | Compuestos heterociclicos terapeuticos. |
DE102005034267A1 (de) * | 2005-07-22 | 2007-01-25 | Bayer Healthcare Ag | 4-Chromenonyl-1,4-dihydropyridine und ihre Verwendung |
DE102005034264A1 (de) * | 2005-07-22 | 2007-02-01 | Bayer Healthcare Ag | 4-Chromenonyl-1,4-dihydropyridincarbonitrile und ihre Verwendung |
CN103254122B (zh) * | 2013-06-19 | 2015-04-22 | 湖南师范大学 | 一种心血管药物尼伐地平的制备方法 |
AR121719A1 (es) | 2020-04-03 | 2022-06-29 | Petra Pharma Corp | Inhibidores alostéricos de cromenona del fosfoinosítido 3-quinasa (pi3k) para el tratamiento de enfermedades |
JP7308369B2 (ja) | 2021-05-03 | 2023-07-13 | ペトラ・ファーマ・コーポレイション | 疾患の治療のためのホスホイノシチド3-キナーゼ(pi3k)のアロステリッククロメノン阻害剤 |
EP4347040A1 (en) | 2021-05-27 | 2024-04-10 | Petra Pharma Corporation | Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2921070A (en) * | 1957-11-05 | 1960-01-12 | Recordati Lab Farmacologico S | Basic esters of 3-methylflavone-8-carboxylic acid |
NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
DE3311005A1 (de) * | 1983-03-25 | 1984-09-27 | Bayer Ag, 5090 Leverkusen | Chromon- und thiochromonsubstituierte 1,4-dihydropyridinderivate, mehrere verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
-
1985
- 1985-10-22 IT IT22578/85A patent/IT1190405B/it active
-
1986
- 1986-10-03 IL IL80229A patent/IL80229A0/xx not_active IP Right Cessation
- 1986-10-14 GR GR862546A patent/GR862546B/el unknown
- 1986-10-15 AR AR86305576A patent/AR243883A1/es active
- 1986-10-15 NO NO864108A patent/NO167570C/no unknown
- 1986-10-16 NZ NZ217964A patent/NZ217964A/en unknown
- 1986-10-20 EP EP86830300A patent/EP0223744B1/en not_active Expired - Lifetime
- 1986-10-20 DE DE8686830300T patent/DE3684244D1/de not_active Expired - Fee Related
- 1986-10-20 AT AT86830300T patent/ATE73453T1/de not_active IP Right Cessation
- 1986-10-20 ZA ZA867941A patent/ZA867941B/xx unknown
- 1986-10-20 ES ES8602677A patent/ES2002425A6/es not_active Expired
- 1986-10-21 IE IE276886A patent/IE58330B1/en not_active IP Right Cessation
- 1986-10-21 JP JP61251553A patent/JPH0772186B2/ja not_active Expired - Lifetime
- 1986-10-21 CA CA000520953A patent/CA1330994C/en not_active Expired - Fee Related
- 1986-10-21 FI FI864260A patent/FI89167C/fi not_active IP Right Cessation
- 1986-10-21 HU HU864363A patent/HU202863B/hu not_active IP Right Cessation
- 1986-10-21 TN TNTNSN86144A patent/TNSN86144A1/fr unknown
- 1986-10-22 PT PT83604A patent/PT83604B/pt not_active IP Right Cessation
- 1986-10-22 EG EG662/86A patent/EG18109A/xx active
- 1986-10-22 AU AU64273/86A patent/AU596382B2/en not_active Ceased
- 1986-10-22 PH PH34400A patent/PH22766A/en unknown
- 1986-10-22 US US06/921,397 patent/US4806534A/en not_active Expired - Fee Related
- 1986-10-22 DK DK506386A patent/DK169408B1/da not_active IP Right Cessation
- 1986-10-22 KR KR1019860008836A patent/KR910009269B1/ko not_active IP Right Cessation
- 1986-10-22 CN CN198686107544A patent/CN86107544A/zh active Pending
-
1992
- 1992-05-23 SG SG551/92A patent/SG55192G/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970129 |