IT1190353B - Cefem composti ad attivita' antibatterica,relativo procedimento di preparazione ed intermedi per questo - Google Patents

Cefem composti ad attivita' antibatterica,relativo procedimento di preparazione ed intermedi per questo

Info

Publication number
IT1190353B
IT1190353B IT20267/85A IT2026785A IT1190353B IT 1190353 B IT1190353 B IT 1190353B IT 20267/85 A IT20267/85 A IT 20267/85A IT 2026785 A IT2026785 A IT 2026785A IT 1190353 B IT1190353 B IT 1190353B
Authority
IT
Italy
Prior art keywords
antibacterial activity
related preparation
intermediate procedure
cefem compounds
cefem
Prior art date
Application number
IT20267/85A
Other languages
English (en)
Other versions
IT8520267A0 (it
Inventor
Yamashita Haruhiro
Oka Masahisa
Okumura Jun
Naito Takayuki
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8520267A0 publication Critical patent/IT8520267A0/it
Application granted granted Critical
Publication of IT1190353B publication Critical patent/IT1190353B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IT20267/85A 1984-04-09 1985-04-05 Cefem composti ad attivita' antibatterica,relativo procedimento di preparazione ed intermedi per questo IT1190353B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09

Publications (2)

Publication Number Publication Date
IT8520267A0 IT8520267A0 (it) 1985-04-05
IT1190353B true IT1190353B (it) 1988-02-16

Family

ID=24393575

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20267/85A IT1190353B (it) 1984-04-09 1985-04-05 Cefem composti ad attivita' antibatterica,relativo procedimento di preparazione ed intermedi per questo

Country Status (31)

Country Link
JP (4) JPS615084A (it)
KR (1) KR870002166B1 (it)
AR (1) AR244694A1 (it)
AT (1) AT388735B (it)
AU (2) AU580990B2 (it)
BE (1) BE902148A (it)
CA (3) CA1276929C (it)
CH (1) CH669197A5 (it)
DD (3) DD249024A5 (it)
DE (1) DE3512225A1 (it)
DK (1) DK155985A (it)
ES (4) ES8607318A1 (it)
FI (1) FI84830C (it)
FR (1) FR2563832B1 (it)
GB (3) GB2157293B (it)
GR (1) GR850883B (it)
HU (2) HU193750B (it)
IE (2) IE58408B1 (it)
IL (1) IL74826A (it)
IT (1) IT1190353B (it)
LU (1) LU85840A1 (it)
MY (1) MY101940A (it)
NL (1) NL192925C (it)
NZ (1) NZ211659A (it)
OA (1) OA07985A (it)
PT (1) PT80246B (it)
RU (1) RU2056425C1 (it)
SE (4) SE466205B (it)
SU (4) SU1436882A3 (it)
YU (2) YU46151B (it)
ZA (1) ZA852236B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (ja) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd 新規セフエム化合物及びその製造法
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
DE3650157T2 (de) * 1985-12-26 1995-05-04 Eisai Co Ltd Cephalosporin-verbindungen.
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
JPH085897B2 (ja) * 1986-11-06 1996-01-24 エーザイ株式会社 ３−プロペニルセフェム誘導体
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
EP0612751A3 (en) * 1988-03-16 1994-09-21 Eisai Co Ltd Compounds for the preparation of cephem derivatives.
JPH0699449B2 (ja) * 1988-03-16 1994-12-07 エーザイ株式会社 セフェム誘導体の合成中間体
FR2655042B1 (fr) * 1989-11-29 1994-01-21 Adir Cie Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
JPH0741484A (ja) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk セフェム化合物及び抗菌剤
KR100248851B1 (ko) * 1994-08-16 2000-04-01 이치로 키타사토 신규 세펨 유도체
JP4033630B2 (ja) 1998-06-22 2008-01-16 バジリア ファルマスーチカ アーゲー プロペニルセファロスポリン誘導体
US7507812B2 (en) 2003-09-09 2009-03-24 Nippon Chemical Industrial Co., Ltd. Process for producing 3-chloromethyl-3-cephem derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (it) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (it) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives

Also Published As

Publication number Publication date
SE8901226L (sv) 1989-04-06
GB2157293B (en) 1988-10-05
SU1487814A3 (ru) 1989-06-15
SE8501680L (sv) 1985-10-10
HU204277B (en) 1991-12-30
GB2157293A (en) 1985-10-23
IE850866L (en) 1985-10-09
ATA103985A (de) 1989-01-15
SE8501680D0 (sv) 1985-04-03
DK155985D0 (da) 1985-04-03
SU1436882A3 (ru) 1988-11-07
AU580990B2 (en) 1989-02-09
YU46151B (sh) 1993-05-28
GB8721347D0 (en) 1987-10-14
NL192925B (nl) 1998-01-05
DD251752A5 (de) 1987-11-25
AU4086285A (en) 1985-10-17
JPH0350754B2 (it) 1991-08-02
ZA852236B (en) 1985-11-27
ES8800949A1 (es) 1987-12-01
DD236735A5 (de) 1986-06-18
GB2194789A (en) 1988-03-16
RU2056425C1 (ru) 1996-03-20
ES8706155A1 (es) 1987-06-01
SE8901225L (sv) 1989-04-06
GB8721346D0 (en) 1987-10-14
SE8901226D0 (sv) 1989-04-06
NZ211659A (en) 1988-11-29
SE470259B (sv) 1993-12-20
DE3512225A1 (de) 1985-10-17
ES542013A0 (es) 1986-06-16
GR850883B (it) 1985-11-25
CA1340638C (en) 1999-07-06
CH669197A5 (de) 1989-02-28
FI851379L (fi) 1985-10-10
JPH0262557B2 (it) 1990-12-26
DE3512225C2 (it) 1990-02-22
IE58403B1 (en) 1993-09-22
IE58408B1 (en) 1993-09-22
ES551550A0 (es) 1987-06-01
DK155985A (da) 1985-10-10
FI84830C (fi) 1992-01-27
SE466205B (sv) 1992-01-13
GB2194789B (en) 1988-10-12
PT80246A (en) 1985-05-01
IL74826A (en) 1990-01-18
AT388735B (de) 1989-08-25
ES8706694A1 (es) 1987-07-01
JPH0357106B2 (it) 1991-08-30
CA1276929C (en) 1990-11-27
HUT37622A (en) 1986-01-23
JPS61143390A (ja) 1986-07-01
BE902148A (fr) 1985-10-09
AU610278B2 (en) 1991-05-16
HU193750B (en) 1987-11-30
JPS615084A (ja) 1986-01-10
GB2194790B (en) 1988-10-05
IL74826A0 (en) 1985-07-31
FR2563832B1 (fr) 1989-08-18
ES551551A0 (es) 1987-07-01
YU60085A (en) 1987-12-31
SE470260B (sv) 1993-12-20
SU1367858A3 (ru) 1988-01-15
IT8520267A0 (it) 1985-04-05
YU118987A (en) 1988-10-31
FI84830B (fi) 1991-10-15
ES557060A0 (es) 1987-12-01
JPH0351716B2 (it) 1991-08-07
GB8508846D0 (en) 1985-05-09
KR870002166B1 (ko) 1987-12-14
AU2504188A (en) 1989-03-02
OA07985A (fr) 1987-01-31
DD249024A5 (de) 1987-08-26
FI851379A0 (fi) 1985-04-04
PT80246B (pt) 1987-10-20
KR850007424A (ko) 1985-12-04
SE8901224L (sv) 1989-04-06
JPS61143387A (ja) 1986-07-01
FR2563832A1 (fr) 1985-11-08
JPS61143391A (ja) 1986-07-01
YU46213B (sh) 1993-05-28
CA1340672C (en) 1999-07-20
LU85840A1 (fr) 1985-12-16
NL192925C (nl) 1998-05-07
SE8901225D0 (sv) 1989-04-06
GB2194790A (en) 1988-03-16
AR244694A1 (es) 1993-11-30
SU1375140A3 (ru) 1988-02-15
SE8901224D0 (sv) 1989-04-06
NL8501002A (nl) 1985-11-01
SE505256C2 (sv) 1997-07-21
MY101940A (en) 1992-02-15
ES8607318A1 (es) 1986-06-16

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970429