IT1143959B - Perfezionamento nelle pastiglie in particolare di prodotti farmaceutici con possibilita' di frazionemanto multiplo per la suddivisione in dosi unitarie e sottodosi - Google Patents

Perfezionamento nelle pastiglie in particolare di prodotti farmaceutici con possibilita' di frazionemanto multiplo per la suddivisione in dosi unitarie e sottodosi

Info

Publication number
IT1143959B
IT1143959B IT48241/80A IT4824180A IT1143959B IT 1143959 B IT1143959 B IT 1143959B IT 48241/80 A IT48241/80 A IT 48241/80A IT 4824180 A IT4824180 A IT 4824180A IT 1143959 B IT1143959 B IT 1143959B
Authority
IT
Italy
Prior art keywords
perfection
tablets
dose
division
possibility
Prior art date
Application number
IT48241/80A
Other languages
English (en)
Other versions
IT8048241A0 (it
Inventor
Michael K Ullman
Stephen R David
Claude E Gallian
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26698095&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1143959(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/024,139 external-priority patent/US4215104A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IT8048241A0 publication Critical patent/IT8048241A0/it
Application granted granted Critical
Publication of IT1143959B publication Critical patent/IT1143959B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
IT48241/80A 1979-03-26 1980-03-24 Perfezionamento nelle pastiglie in particolare di prodotti farmaceutici con possibilita' di frazionemanto multiplo per la suddivisione in dosi unitarie e sottodosi IT1143959B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/024,139 US4215104A (en) 1979-03-26 1979-03-26 Multi-fractionable tablet structure
US06/121,615 US4258027A (en) 1979-03-26 1980-02-14 Multi-fractionable tablet structure

Publications (2)

Publication Number Publication Date
IT8048241A0 IT8048241A0 (it) 1980-03-24
IT1143959B true IT1143959B (it) 1986-10-29

Family

ID=26698095

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48241/80A IT1143959B (it) 1979-03-26 1980-03-24 Perfezionamento nelle pastiglie in particolare di prodotti farmaceutici con possibilita' di frazionemanto multiplo per la suddivisione in dosi unitarie e sottodosi

Country Status (26)

Country Link
US (1) US4258027A (it)
AT (1) AT372853B (it)
AU (1) AU533115B2 (it)
CA (1) CA1133393A (it)
CH (1) CH644515A5 (it)
CY (1) CY1311A (it)
DE (1) DE3011680C2 (it)
DK (1) DK155566C (it)
ES (1) ES263036Y (it)
FI (1) FI800884A (it)
FR (1) FR2452284A1 (it)
GB (1) GB2047095B (it)
GR (1) GR67751B (it)
HK (1) HK92985A (it)
HU (1) HU191022B (it)
IE (1) IE49579B1 (it)
IL (1) IL59697A (it)
IT (1) IT1143959B (it)
KE (1) KE3571A (it)
LU (1) LU82297A1 (it)
MY (1) MY8600287A (it)
NL (1) NL189175C (it)
NO (1) NO157048C (it)
PH (1) PH16802A (it)
SE (1) SE446061B (it)
YU (1) YU42100B (it)

Families Citing this family (61)

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US4547358A (en) * 1980-05-06 1985-10-15 Mead Johnson & Company Sustained release tablet containing at least 95 percent theophylline
ZA813205B (en) * 1980-12-05 1983-03-30 Smith Kline French Lab Dosage units
US4465660A (en) * 1981-04-01 1984-08-14 Mead Johnson & Company Sustained release tablet containing at least 95 percent theophylline
DE3314003A1 (de) * 1983-04-18 1984-10-18 Boehringer Ingelheim KG, 6507 Ingelheim Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
DE3610878A1 (de) * 1986-04-01 1987-10-08 Boehringer Ingelheim Kg Formlinge aus pellets
US4793493A (en) * 1986-09-18 1988-12-27 Makiej Jr Walter J Multidose capsules
US4735805A (en) * 1987-03-11 1988-04-05 The Upjohn Company Bisectable drug tablet
US5009896A (en) * 1989-10-04 1991-04-23 Akzo N.V. Multi-fractionable tablet structure
US5061494A (en) * 1990-06-14 1991-10-29 The Upjohn Comany Tri-scored drug tablet
GB9101502D0 (en) * 1991-01-23 1991-03-06 Controlled Therapeutics Sct Controlled release compositions
TW407502U (en) * 1991-09-10 2000-10-01 Takeda Chemical Industries Ltd Divisible tablet
DE4342146C1 (de) * 1993-12-10 1995-07-06 Notter Gmbh Ringtablette
DE9415022U1 (de) * 1994-09-15 1994-11-17 Azupharma GmbH, 70839 Gerlingen Tablettenartiger Körper mit Bruchkerbe
US5756124A (en) * 1995-08-07 1998-05-26 Invamed, Inc. Multi-scored pharmaceutical tablets
GB9624563D0 (en) * 1996-11-27 1997-01-15 Smithkline Beecham Plc Product
DE19837684A1 (de) * 1998-08-19 2000-02-24 Knoll Ag Exakt teilbare Tablette
GB9914620D0 (en) * 1999-06-23 1999-08-25 Eu Pharma Ltd Divisible tablets
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
TW200502000A (en) * 2003-03-28 2005-01-16 Kyowa Hakko Kogyo Kk Dividing tablet
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
FR2859632B1 (fr) * 2003-09-15 2005-11-18 Arrow Generiques Comprime multisecable a observance amelioree.
US8157788B2 (en) * 2003-11-06 2012-04-17 Paolo L. Manfredi Multi-site drug delivery platform
AU2005245028B2 (en) 2004-05-21 2010-12-09 Accu-Break Technologies, Inc. Pharmaceutical tablets having a relatively inactive segment
US7838031B2 (en) * 2004-05-21 2010-11-23 Lawrence Solomon Method of administering a partial dose using a segmented pharmaceutical tablet
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
EP3205337A1 (en) * 2005-08-18 2017-08-16 Teijin Pharma Limited Formulation having accurate dose-dividing function
WO2007121356A2 (en) * 2006-04-13 2007-10-25 Accu-Break Technologies Method of treatment with predictably breakable pharmaceutical tablets
US20080264430A2 (en) * 2006-11-21 2008-10-30 Edmund Roschak Methods and devices for accessing the heart
US7985419B1 (en) 2006-12-22 2011-07-26 Watson Laboratories, Inc. Divisible tablet and associated methods
BRPI0906467C1 (pt) 2008-01-25 2021-05-25 Gruenenthal Gmbh forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada
LT2273983T (lt) 2008-05-09 2016-10-25 Grünenthal GmbH Tarpinės miltelių kompozicijos gamybos būdas ir galutinė kieta dozavimo forma naudojant purškalo kietinimo stadija
AU2010275754B2 (en) 2009-07-22 2014-05-15 Grünenthal GmbH Tamper-resistant dosage form for oxidation-sensitive opioids
EP2456427B1 (en) 2009-07-22 2015-03-04 Grünenthal GmbH Hot-melt extruded controlled release dosage form
WO2012028319A1 (en) 2010-09-02 2012-03-08 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
MX2013002293A (es) 2010-09-02 2013-05-09 Gruenenthal Gmbh Forma de dosificacion resistente a alteracion que comprende un polimero anionico.
US8383135B2 (en) * 2010-12-03 2013-02-26 Richard C. Fuisz Solid dosage form that promotes reliable oral, esophageal and GI transit
LT2736497T (lt) 2011-07-29 2017-11-10 Grünenthal GmbH Sugadinimui atspari tabletė, pasižyminti greitu vaisto atpalaidavimu
BR112014002022A2 (pt) 2011-07-29 2017-02-21 Gruenenthal Gmbh comprimido resistente à violação proporcionando liberação de fármaco imediata
US20130225697A1 (en) 2012-02-28 2013-08-29 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
AU2013248351B2 (en) 2012-04-18 2018-04-26 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
CA2907950A1 (en) 2013-05-29 2014-12-04 Grunenthal Gmbh Tamper-resistant dosage form containing one or more particles
JP6466417B2 (ja) 2013-05-29 2019-02-06 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 二峰性放出プロファイルを有する改変防止（ｔａｍｐｅｒ−ｒｅｓｉｓｔａｎｔ）剤形
EA032465B1 (ru) 2013-07-12 2019-05-31 Грюненталь Гмбх Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления
AU2014356581C1 (en) 2013-11-26 2020-05-28 Grunenthal Gmbh Preparation of a powdery pharmaceutical composition by means of cryo-milling
CN106572980A (zh) 2014-05-12 2017-04-19 格吕伦塔尔有限公司 包含他喷他多的防篡改即释胶囊制剂
CN106456550A (zh) 2014-05-26 2017-02-22 格吕伦塔尔有限公司 避免乙醇剂量倾泻的多颗粒
AU2016251854A1 (en) 2015-04-24 2017-10-19 Grunenthal Gmbh Tamper-resistant dosage form with immediate release and resistance against solvent extraction
JP2018526414A (ja) 2015-09-10 2018-09-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護
DE102016119675A1 (de) 2016-10-14 2018-04-19 Ritter Pharma-Technik Gmbh Tablette mit Bruchwinkel und senkrecht zur Pressrichtung eingebrachter Teilungskerbe
USD827721S1 (en) * 2017-03-15 2018-09-04 Click-Block Corporation Triangular tile magnetic toy
USD906294S1 (en) * 2019-01-28 2020-12-29 Compal Electronics, Inc. Set of earbuds
JP1637714S (it) * 2019-02-08 2019-07-29
JP1640288S (it) * 2019-02-08 2019-09-02
JP1637715S (it) * 2019-02-08 2019-07-29
US20210378968A1 (en) * 2020-05-28 2021-12-09 Johnson & Johnson Consumer Inc. Multi-cavity customizable dosage forms

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
US94644A (en) * 1869-09-07 Improvement in horse hat-forks
FR438385A (fr) * 1911-01-02 1912-05-15 Fernande Barry Le Grand Bijoux et parures en bonbons et pates de fruits ou toute autre pate
US1836604A (en) * 1929-06-01 1931-12-15 Simon M Meyer Sugar unit
US2052376A (en) * 1933-05-18 1936-08-25 Edgar G Zellers Insoluble pill or tablet for internal medicinal uses
DE1200790B (de) * 1961-12-06 1965-09-16 Thomas L Cooper Zerlegbare Tablette
GB993291A (en) * 1961-12-06 1965-05-26 Thomas Lee Cooper Tablets, pills, pellets and the like
US3336200A (en) * 1963-05-28 1967-08-15 Warner Lambert Pharmaceutical Tablet structure
CH502891A (de) * 1967-11-21 1971-02-15 Ciba Geigy Ag Technische, gekerbte Tablette
US3723614A (en) * 1971-01-06 1973-03-27 Ciba Geigy Ag Maltese-cross scored tablet
GB1368574A (en) * 1971-02-12 1974-10-02 Ives Lab Inc Divisible tablet
GB1387643A (en) * 1971-03-16 1975-03-19 Ives Lab Inc Divisible tablet
US3883647A (en) * 1972-12-06 1975-05-13 Ives Lab Tablet formulation

Also Published As

Publication number Publication date
CA1133393A (en) 1982-10-12
HK92985A (en) 1985-11-29
DE3011680A1 (de) 1980-10-09
GR67751B (it) 1981-09-18
US4258027A (en) 1981-03-24
KE3571A (en) 1985-11-08
IT8048241A0 (it) 1980-03-24
DK128580A (da) 1980-09-27
DK155566C (da) 1989-09-11
NO157048C (no) 1988-01-27
ES263036U (es) 1982-11-01
NL189175C (nl) 1993-02-01
YU77280A (en) 1983-04-30
AU533115B2 (en) 1983-11-03
GB2047095A (en) 1980-11-26
SE446061B (sv) 1986-08-11
CH644515A5 (de) 1984-08-15
IE800612L (en) 1980-09-26
LU82297A1 (fr) 1980-10-08
ES263036Y (es) 1984-04-01
SE8002303L (sv) 1980-09-27
FR2452284A1 (fr) 1980-10-24
YU42100B (en) 1988-04-30
FR2452284B1 (it) 1983-06-17
ATA160880A (de) 1983-04-15
IL59697A (en) 1983-11-30
HU191022B (en) 1986-12-28
NL8001700A (nl) 1980-09-30
DK155566B (da) 1989-04-24
AT372853B (de) 1983-11-25
CY1311A (en) 1986-03-28
NO800847L (no) 1980-09-29
AU5647480A (en) 1980-10-02
MY8600287A (en) 1986-12-31
IL59697A0 (en) 1980-06-30
FI800884A (fi) 1980-09-27
GB2047095B (en) 1983-08-24
NL189175B (nl) 1992-09-01
PH16802A (en) 1984-03-01
NO157048B (no) 1987-10-05
DE3011680C2 (de) 1997-04-30
IE49579B1 (en) 1985-10-30

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970329