IS2666B - Aðferð við ljósfræðilega hreinsun á bensimidasólafleiðum með hækkað hlutfall enantíómera - Google Patents

Aðferð við ljósfræðilega hreinsun á bensimidasólafleiðum með hækkað hlutfall enantíómera

Info

Publication number
IS2666B
IS2666B IS4638A IS4638A IS2666B IS 2666 B IS2666 B IS 2666B IS 4638 A IS4638 A IS 4638A IS 4638 A IS4638 A IS 4638A IS 2666 B IS2666 B IS 2666B
Authority
IS
Iceland
Prior art keywords
increased
benzimidazole derivatives
optical purification
enantiomer ratio
purification
Prior art date
Application number
IS4638A
Other languages
English (en)
Other versions
IS4638A (is
Inventor
Sverker Von Unge
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20397468&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS2666(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Publication of IS4638A publication Critical patent/IS4638A/is
Publication of IS2666B publication Critical patent/IS2666B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS4638A 1995-07-03 1997-01-21 Aðferð við ljósfræðilega hreinsun á bensimidasólafleiðum með hækkað hlutfall enantíómera IS2666B (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9500817 1995-07-03
PCT/SE1996/000841 WO1997002261A1 (en) 1995-07-03 1996-06-26 A process for the optical purification of enantiomerically enriched benzimidazole derivatives

Publications (2)

Publication Number Publication Date
IS4638A IS4638A (is) 1997-12-22
IS2666B true IS2666B (is) 2010-08-15

Family

ID=20397468

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4638A IS2666B (is) 1995-07-03 1997-01-21 Aðferð við ljósfræðilega hreinsun á bensimidasólafleiðum með hækkað hlutfall enantíómera

Country Status (37)

Country Link
US (1) US5929244A (is)
EP (2) EP1498416A1 (is)
JP (1) JP4195507B2 (is)
KR (1) KR100451078B1 (is)
CN (1) CN1098261C (is)
AT (1) ATE418549T1 (is)
AU (1) AU698638B2 (is)
BR (1) BR9609450A (is)
CA (1) CA2226184C (is)
CZ (1) CZ295430B6 (is)
DE (1) DE69637788D1 (is)
DK (1) DK0836601T3 (is)
DZ (1) DZ2057A1 (is)
EE (1) EE03444B1 (is)
ES (1) ES2318850T3 (is)
HK (1) HK1010193A1 (is)
HR (1) HRP960232A2 (is)
HU (1) HUP9901717A3 (is)
IL (1) IL122811A (is)
IS (1) IS2666B (is)
MA (1) MA23921A1 (is)
MY (1) MY114018A (is)
NO (1) NO313008B1 (is)
NZ (1) NZ311842A (is)
PL (1) PL186702B1 (is)
PT (1) PT836601E (is)
RS (1) RS49826B (is)
RU (1) RU2144031C1 (is)
SA (1) SA96170103B1 (is)
SI (1) SI0836601T1 (is)
SK (1) SK284780B6 (is)
TN (1) TNSN96090A1 (is)
TR (1) TR199701754T1 (is)
TW (1) TW444010B (is)
UA (1) UA49838C2 (is)
WO (1) WO1997002261A1 (is)
ZA (1) ZA965205B (is)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
AU6551198A (en) * 1997-05-30 1998-12-30 Dr. Reddy's Research Foundation Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
CA2320963A1 (en) * 1998-01-30 1999-08-05 Sepracor, Inc. R-lansoprazole compositions and methods
SE9900274D0 (sv) 1999-01-28 1999-01-28 Astra Ab New compound
TWI275587B (en) 1999-06-17 2007-03-11 Takeda Chemical Industries Ltd A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
WO2001002389A1 (fr) * 1999-06-30 2001-01-11 Takeda Chemical Industries, Ltd. Cristaux de composes benzimidazole
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
CA2409044C (en) 2000-05-15 2013-02-19 Takeda Chemical Industries, Ltd. Improved recrystallization processes for obtaining anhydrous optically active lansoprazole
JP5412023B2 (ja) 2000-08-04 2014-02-12 武田薬品工業株式会社 ベンズイミダゾール化合物の塩およびその用途
TWI290922B (en) 2000-12-01 2007-12-11 Takeda Chemical Industries Ltd Production method of crystals
KR100433735B1 (ko) * 2001-06-27 2004-06-04 주식회사 씨트리 결정형 ⅰ을 갖는 란소프라졸의 제조방법
SE0104295D0 (sv) * 2001-12-18 2001-12-18 Astrazeneca Ab New process
US20040006111A1 (en) * 2002-01-25 2004-01-08 Kenneth Widder Transmucosal delivery of proton pump inhibitors
ES2534713T3 (es) 2002-10-16 2015-04-27 Takeda Pharmaceutical Company Limited Preparaciones sólidas estables
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
DE10254167A1 (de) 2002-11-20 2004-06-09 Icon Genetics Ag Verfahren zur Kontrolle von zellulären Prozessen in Pflanzen
US7301030B2 (en) 2002-12-06 2007-11-27 Nycomed Gmbh Process for preparing (S)-pantoprazole
RS52667B (en) 2002-12-06 2013-06-28 Nycomed Gmbh PROCEDURE FOR PREPARING OPTICALLY CLEAN UNITS
US20040248942A1 (en) * 2003-02-20 2004-12-09 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
EP1606279A1 (en) * 2003-02-28 2005-12-21 Ranbaxy Laboratories, Ltd. Polymorphs of s-omeprazole
JP2006528182A (ja) * 2003-07-18 2006-12-14 サンタラス インコーポレイティッド 薬学的製剤および酸に起因する消化器疾患の治療法
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US7005732B2 (en) * 2003-10-21 2006-02-28 Honeywell International Inc. Methods and systems for providing MEMS devices with a top cap and upper sense plate
FR2863609A1 (fr) * 2003-12-15 2005-06-17 Isochem Sa Procede d'enrichissement enantiomerique d'un melange d'enantiomeres d'alpha-aminoacides
SE0400410D0 (sv) * 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AU2005264864B2 (en) 2004-06-16 2011-08-11 Takeda Pharmaceutical Company Limited Multiple PPI dosage form
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
US7553857B2 (en) 2005-12-23 2009-06-30 Lek Pharmaceuticals D.D. S-omeprazole magnesium
US7786309B2 (en) * 2006-06-09 2010-08-31 Apotex Pharmachem Inc. Process for the preparation of esomeprazole and salts thereof
FR2909380B1 (fr) * 2006-12-04 2009-02-20 Sidem Pharma Sa Sa Conglomerats de sels de potassium de tenatoprazole
EP1947099A1 (en) 2007-01-18 2008-07-23 LEK Pharmaceuticals D.D. Process for solvent removal from omeprazole salts
WO2008152462A1 (en) * 2007-06-15 2008-12-18 Emcure Pharmaceuticals Limited A process of sulfoxidation of biologically active compounds
CN101323609B (zh) * 2007-06-15 2013-05-01 成都福瑞生物工程有限公司 不对称氧化硫醚成亚砜合成对映体含量高的苯并咪唑衍生物的方法
FR2920428B1 (fr) * 2007-08-29 2012-06-15 Univ Rouen Procede de dedoublement de sels de l'omeprazole
UY31695A (es) 2008-03-10 2009-11-10 Takeda Pharmaceutical Cristal de compuestos de bencimidazol
WO2010058409A2 (en) 2008-11-18 2010-05-27 Hetero Research Foundation Optical purification of esomeprazole
KR101001646B1 (ko) * 2008-12-12 2010-12-17 한미약품 주식회사 (ｒ)-(+)-란소프라졸의 제조방법 및 이에 사용되는 중간체
WO2011004387A2 (en) 2009-06-18 2011-01-13 Matrix Laboratories Ltd Process for the preparation of dexlansoprazole polymorphic forms
US8748619B2 (en) 2009-11-12 2014-06-10 Hetero Research Foundation Process for the resolution of omeprazole
CA2788147A1 (en) 2010-01-29 2011-08-04 Ranbaxy Laboratories Limited Process for the preparation of crystalline forms of dexlansoprazole
EP3176164B1 (en) * 2014-07-30 2019-08-21 Aetas Pharma Co. Ltd. Optical isomer of 1,4-benzothiazepine-1-oxide derivative, and pharmaceutical composition prepared using same
EP3064495B1 (en) 2015-03-06 2016-12-14 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Improved process for the preparation of optically pure esomeprazole

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU4640985A (en) * 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
ATE110069T1 (de) * 1989-11-29 1994-09-15 Toa Eiyo Ltd Cycloheptenopyridinderivate, verfahren zu ihrer herstellung und diese enthaltende antiulkusmitteln.
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
IS4232A (is) * 1993-12-06 1995-06-07 Astra Aktiebolag Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds

Also Published As

Publication number Publication date
IL122811A0 (en) 1998-08-16
IS4638A (is) 1997-12-22
SK284780B6 (sk) 2005-11-03
MA23921A1 (fr) 1996-12-31
KR100451078B1 (ko) 2004-11-16
IL122811A (en) 2000-11-21
ZA965205B (en) 1997-01-03
AU6324096A (en) 1997-02-05
CA2226184C (en) 2008-08-05
PL186702B1 (pl) 2004-02-27
ATE418549T1 (de) 2009-01-15
UA49838C2 (uk) 2002-10-15
PL324394A1 (en) 1998-05-25
CZ421197A3 (cs) 1998-06-17
SK179397A3 (en) 1998-09-09
KR19990028631A (ko) 1999-04-15
YU37696A (sh) 1999-03-04
DK0836601T3 (da) 2009-03-16
CZ295430B6 (cs) 2005-08-17
BR9609450A (pt) 1999-03-02
JPH11508590A (ja) 1999-07-27
EE03444B1 (et) 2001-06-15
NO976030L (no) 1998-02-09
TW444010B (en) 2001-07-01
MY114018A (en) 2002-07-31
DZ2057A1 (fr) 2002-10-20
EE9700368A (et) 1998-06-15
EP0836601B1 (en) 2008-12-24
NO976030D0 (no) 1997-12-22
TR199701754T1 (xx) 1998-04-21
RU2144031C1 (ru) 2000-01-10
NO313008B1 (no) 2002-07-29
PT836601E (pt) 2009-02-17
TNSN96090A1 (fr) 2005-03-15
MX9800160A (es) 1998-03-31
JP4195507B2 (ja) 2008-12-10
DE69637788D1 (de) 2009-02-05
HUP9901717A3 (en) 2002-03-28
CA2226184A1 (en) 1997-01-23
RS49826B (sr) 2008-08-07
NZ311842A (en) 1998-12-23
SA96170103B1 (ar) 2006-07-30
WO1997002261A1 (en) 1997-01-23
EP1498416A1 (en) 2005-01-19
US5929244A (en) 1999-07-27
AU698638B2 (en) 1998-11-05
HUP9901717A2 (hu) 2000-04-28
HRP960232A2 (en) 1998-02-28
CN1098261C (zh) 2003-01-08
EP0836601A1 (en) 1998-04-22
CN1193971A (zh) 1998-09-23
HK1010193A1 (en) 1999-06-17
SI0836601T1 (sl) 2009-04-30
ES2318850T3 (es) 2009-05-01

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