IN2014DN00145A - - Google Patents

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Info

Publication number: IN2014DN00145A
Authority: IN; India
Prior art keywords: solid forms; amide; pharmaceutical compositions; present; relates
Prior art date: 2011-06-21

Application number

Other languages

English (en)

Inventor

Isabelle Sylvie Gallou

Cornelius Gauer

Frank Stowasser

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-06-21

Filing date

2012-06-19

Publication date

2015-05-22

2012-06-19 Application filed by Novartis Ag filed Critical Novartis Ag

2015-05-22 Publication of IN2014DN00145A publication Critical patent/IN2014DN00145A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Oncology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IN145DEN2014 2011-06-21 2012-06-19 IN2014DN00145A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201161499222P	2011-06-21	2011-06-21
PCT/EP2012/061756 WO2012175522A1 (en)	2011-06-21	2012-06-19	Polymorphs of (s)-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)-pyridin-4-yl]-thiazol-2-yl}-amide

Publications (1)

Publication Number	Publication Date
IN2014DN00145A true IN2014DN00145A (es)	2015-05-22

Family

ID=46319784

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IN145DEN2014 IN2014DN00145A (es)	2011-06-21	2012-06-19

Country Status (11)

Country	Link
US (1)	US9006270B2 (es)
EP (1)	EP2723733A1 (es)
JP (1)	JP2014517049A (es)
KR (1)	KR20140033432A (es)
CN (1)	CN103619840B (es)
BR (1)	BR112013032687A2 (es)
CA (1)	CA2839621A1 (es)
IN (1)	IN2014DN00145A (es)
MX (1)	MX2013014887A (es)
RU (1)	RU2014101626A (es)
WO (1)	WO2012175522A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG10201407881WA (en)	2009-11-27	2015-01-29	Genzyme Corp	An amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
EP2830619A1 (en) *	2012-03-30	2015-02-04	Novartis AG	Compounds for use in the treatment of neuroblastoma, ewing's sarcoma or rhabdomyosarcoma
DK3076969T3 (da) *	2013-12-06	2021-11-22	Novartis Ag	Doseringsregime for en alfa-isoform-selektiv phosphatidylinositol-3-kinase-hæmmer
RU2690685C2 (ru) *	2014-10-03	2019-06-05	Новартис Аг	Фармацевтические композиции, содержащие алпелисиб
EP3956330A4 (en)	2019-04-18	2023-01-18	The Johns Hopkins University	SUBSTITUTED 2-AMINO-PYRAZOLYL-[1,2,4]TRIAZOLO[1,5A]PYRIDINE DERIVATIVES AND THEIR USE
CN112961090A (zh) *	2019-12-13	2021-06-15	武汉九州钰民医药科技有限公司	合成Alpelisib的关键中间体及其制备方法
CN110964005A (zh) *	2019-12-16	2020-04-07	武汉九州钰民医药科技有限公司	一种Alpelisib的制备工艺
CN111057051A (zh) *	2019-12-16	2020-04-24	武汉九州钰民医药科技有限公司	PI3K抑制剂Alpelisib的新合成方法
JP2022061050A (ja)	2020-10-06	2022-04-18	エルジーディスプレイカンパニーリミテッド	伝送装置及び表示システム
KR20240004683A (ko) *	2021-05-03	2024-01-11	노파르티스 아게	알펠리십 제형

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UY29149A1 (es) *	2004-10-07	2006-05-31	Boehringer Ingelheim Int	Tiazolil-dihidro-indazoles
EP2016075A1 (en) *	2006-05-03	2009-01-21	AstraZeneca AB	Thiazole derivatives and their use as anti-tumour agents
UA104147C2 (uk)	2008-09-10	2014-01-10	Новартис Аг	Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
AR082418A1 (es) *	2010-08-02	2012-12-05	Novartis Ag	Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico

2012
- 2012-06-19 US US14/127,027 patent/US9006270B2/en not_active Expired - Fee Related
- 2012-06-19 EP EP12728285.3A patent/EP2723733A1/en not_active Withdrawn
- 2012-06-19 WO PCT/EP2012/061756 patent/WO2012175522A1/en active Application Filing
- 2012-06-19 JP JP2014516316A patent/JP2014517049A/ja active Pending
- 2012-06-19 BR BR112013032687A patent/BR112013032687A2/pt not_active IP Right Cessation
- 2012-06-19 CN CN201280030432.6A patent/CN103619840B/zh not_active Expired - Fee Related
- 2012-06-19 CA CA2839621A patent/CA2839621A1/en not_active Abandoned
- 2012-06-19 MX MX2013014887A patent/MX2013014887A/es not_active Application Discontinuation
- 2012-06-19 RU RU2014101626/04A patent/RU2014101626A/ru not_active Application Discontinuation
- 2012-06-19 IN IN145DEN2014 patent/IN2014DN00145A/en unknown
- 2012-06-19 KR KR1020137033590A patent/KR20140033432A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
MX2013014887A (es)	2014-02-17
CA2839621A1 (en)	2012-12-27
US9006270B2 (en)	2015-04-14
BR112013032687A2 (pt)	2016-08-30
WO2012175522A1 (en)	2012-12-27
AU2012274141A1 (en)	2013-12-12
CN103619840B (zh)	2016-01-20
EP2723733A1 (en)	2014-04-30
JP2014517049A (ja)	2014-07-17
RU2014101626A (ru)	2015-07-27
KR20140033432A (ko)	2014-03-18
CN103619840A (zh)	2014-03-05
AU2012274141B2 (en)	2015-12-24
US20140171470A1 (en)	2014-06-19

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