IN2012DN00338A - - Google Patents

Download PDF

Info

Publication number
IN2012DN00338A
IN2012DN00338A IN338DEN2012A IN2012DN00338A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A IN 338DEN2012 A IN338DEN2012 A IN 338DEN2012A IN 2012DN00338 A IN2012DN00338 A IN 2012DN00338A
Authority
IN
India
Prior art keywords
methods
relates
present
region containing
containing protein
Prior art date
Application number
Other languages
English (en)
Inventor
Soice Neil
Hubbard Dana
Zhang Yu
Harmzik James
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of IN2012DN00338A publication Critical patent/IN2012DN00338A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
IN338DEN2012 2009-08-07 2010-08-05 IN2012DN00338A (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27370909P 2009-08-07 2009-08-07
PCT/US2010/044539 WO2011017514A1 (en) 2009-08-07 2010-08-05 Methods for purifying a target protein from one or more impurities in a sample

Publications (1)

Publication Number Publication Date
IN2012DN00338A true IN2012DN00338A (hu) 2015-05-22

Family

ID=43544660

Family Applications (1)

Application Number Title Priority Date Filing Date
IN338DEN2012 IN2012DN00338A (hu) 2009-08-07 2010-08-05

Country Status (9)

Country Link
US (1) US8536316B2 (hu)
EP (1) EP2462157B1 (hu)
JP (2) JP5791602B2 (hu)
KR (1) KR101415660B1 (hu)
CN (2) CN107188960A (hu)
ES (1) ES2817802T3 (hu)
IN (1) IN2012DN00338A (hu)
SG (1) SG177577A1 (hu)
WO (1) WO2011017514A1 (hu)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011090719A2 (en) * 2009-12-29 2011-07-28 Dr. Reddy's Laboratories Ltd. Protein purification by ion exchange
KR20150023923A (ko) 2010-07-30 2015-03-05 이엠디 밀리포어 코포레이션 크로마토그래피 매질 및 방법
SG185920A1 (en) 2011-05-27 2012-12-28 Abbott Biotherapeutics Corp Dac hyp compositions and methods
US20140187749A1 (en) * 2011-06-16 2014-07-03 Dsm Ip Assets B.V. Single unit chromatography antibody purification
AU2012282960A1 (en) * 2011-07-08 2014-01-16 Merck Sharp & Dohme Corp. Method for purifying Fc-fusion protein
KR20140062469A (ko) * 2011-07-20 2014-05-23 젭테온 인코포레이티드 폴리펩티드 분리 방법
BR112014002133A2 (pt) * 2011-08-01 2017-02-21 Avaxia Biologics Inc anticorpo policlonal bovino específico para tnf humano
WO2013028330A2 (en) * 2011-08-19 2013-02-28 Emd Millipore Corporation Methods of reducing level of one of more impurities in a sample during protein purification
SG11201400236YA (en) * 2011-09-01 2014-03-28 Human Genome Sciences Inc Viral clearance methods
EP2578286A1 (en) 2011-10-04 2013-04-10 Merck Patent GmbH Method and apparatus for chromatographic purification
US20140301977A1 (en) * 2011-11-02 2014-10-09 Genentech, Inc. Overload and elute chromatography
WO2013075740A1 (en) 2011-11-23 2013-05-30 Sanofi Antibody purification method
CN102492040B (zh) * 2011-12-29 2014-06-25 嘉和生物药业有限公司 一种抗her2或/和抗her3抗体蛋白的纯化方法
SG10201701224UA (en) * 2012-03-12 2017-04-27 Merck Patent Gmbh Removal of protein aggregates from biopharmaceutical preparations in a flowthrough mode
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
WO2014034644A1 (ja) 2012-08-27 2014-03-06 旭化成メディカル株式会社 温度応答性クロマトグラフィーによる抗体の精製方法
PE20150996A1 (es) 2012-09-11 2015-08-01 Coherus Biosciences Inc Etanercept correctamente plegado de alta pureza y excelente rendimiento
CN104968403A (zh) 2012-09-17 2015-10-07 格雷斯公司 色谱介质和装置
US10421795B2 (en) 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
MX346385B (es) 2013-02-14 2017-03-16 Nanopareil Llc Fieltros hibridos de nanofibras electrohiladas.
MX368177B (es) * 2013-05-06 2019-09-23 Sanofi Sa Proceso continuo de múltiples etapas para purificar anticuerpos.
CA2922832A1 (en) * 2013-09-05 2015-03-12 Genentech, Inc. Method for chromatography reuse
KR20160054597A (ko) 2013-09-17 2016-05-16 가부시키가이샤 가네카 신규 항체 정제 방법 및 그로부터 얻어지는 항체, 및 양이온 교환기를 사용한 신규 항체 정제법 및 그로부터 얻어지는 항체
CN105980047B (zh) 2013-12-12 2019-01-04 Emd密理博公司 使用含丙烯酰胺的过滤器分离蛋白
EP3105580B1 (en) * 2014-02-14 2023-10-04 Cytiva Sweden AB Automated multi-step purification system
EP3116891B1 (en) 2014-03-10 2020-02-12 Richter Gedeon Nyrt. Immunoglobulin purification using pre-cleaning steps
CN104826617B (zh) * 2014-03-25 2017-06-13 西北大学 一种用于蛋白质分离的wax/hic双功能混合模式色谱固定相及其制备方法
WO2015168383A1 (en) 2014-05-02 2015-11-05 W. R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
US20170183376A1 (en) * 2014-06-24 2017-06-29 Insight Biopharmaceuticals Ltd. Methods of purifying antibodies
DE102014010353A1 (de) 2014-07-10 2016-01-14 Sartorius Stedim Biotech Gmbh Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien
SG11201703399QA (en) 2014-12-08 2017-05-30 Emd Millipore Corp Mixed bed ion exchange adsorber
KR102566292B1 (ko) 2015-06-05 2023-08-10 더블유.알. 그레이스 앤드 캄파니-콘. 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법
US20200325169A1 (en) * 2016-04-05 2020-10-15 Haemonetics Corporation Methods and Devices for the Enrichment of Immunoglobulin from Blood
CN107964044B (zh) * 2016-10-19 2021-11-19 无锡科捷诺生物科技有限责任公司 从乳样中纯化抗cd20单克隆抗体的方法
EP3769083A1 (en) 2018-03-21 2021-01-27 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
EP3898650A4 (en) * 2018-12-21 2022-11-16 Wuxi Biologics Ireland Limited METHOD FOR IMPROVING AGGREGATE REMOVAL BY PROTEIN A CHROMATOGRAPHY
FR3099066B1 (fr) 2019-07-26 2021-08-13 Novasep Process Procédé de purification d’une substance cible avec inactivation virale
TW202128264A (zh) * 2019-09-25 2021-08-01 瑞士商赫孚孟拉羅股份公司 使用經預測之溶離緩衝鹽濃度的陽離子層析法
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法
CN113845562A (zh) * 2020-06-28 2021-12-28 佛山汉腾生物科技有限公司 目的蛋白纯化方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4490937A (en) * 1981-12-07 1985-01-01 Amcor Ltd. Insect electrocution device
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5256694A (en) * 1984-09-22 1993-10-26 Basf Aktiengesellschaft Diarylacetylenes, their preparation and their use
US5091178A (en) * 1986-02-21 1992-02-25 Oncogen Tumor therapy with biologically active anti-tumor antibodies
US6054051A (en) * 1996-01-17 2000-04-25 Genentech, Inc. Tangential-flow filtration system
PT1501369E (pt) * 2002-04-26 2015-09-21 Genentech Inc Purificação de proteínas com base na não afinidade
CA2497364C (en) * 2002-09-11 2013-03-19 Chugai Seiyaku Kabushiki Kaisha Protein purification method
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
KR20070072510A (ko) * 2004-08-30 2007-07-04 론자 바이올로직스 피엘씨 항체 정제를 위한 친화도- 및 이온 교환- 크로마토그래피
US20100234577A1 (en) * 2006-06-14 2010-09-16 Smithkline Beecham Corporation Methods for purifying antibodies using ceramic hydroxyapatite
UA99263C2 (ru) * 2006-08-28 2012-08-10 Арес Трейдинг С.А. СПОСОБ ОЧИСТКИ Fc-СЛИТОГО БЕЛКА
EP2061803B2 (en) * 2006-08-28 2022-11-16 Ares Trading S.A. Process for the purification of fc-containing proteins
EP2114984A2 (en) * 2007-01-17 2009-11-11 Merck Serono S.A. Process for the purification of fc-containing proteins
US9433922B2 (en) * 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
US20090149638A1 (en) * 2007-10-03 2009-06-11 Ley Arthur C Systems and methods for purifying proteins
EP2281000A2 (en) * 2008-05-15 2011-02-09 Novo Nordisk A/S Antibody purification process
BRPI0920572A8 (pt) * 2008-10-20 2015-10-27 Abbott Lab Inativação viral durante a purificação dos anticorpos

Also Published As

Publication number Publication date
KR101415660B1 (ko) 2014-07-16
CN107188960A (zh) 2017-09-22
EP2462157A1 (en) 2012-06-13
US8536316B2 (en) 2013-09-17
WO2011017514A1 (en) 2011-02-10
EP2462157A4 (en) 2012-12-26
JP2015157846A (ja) 2015-09-03
JP5791602B2 (ja) 2015-10-07
EP2462157B1 (en) 2020-06-17
US20110065901A1 (en) 2011-03-17
CN102574911A (zh) 2012-07-11
CN102574911B (zh) 2017-06-06
KR20120089432A (ko) 2012-08-10
SG177577A1 (en) 2012-03-29
ES2817802T3 (es) 2021-04-08
JP2013501721A (ja) 2013-01-17
JP6335838B2 (ja) 2018-05-30

Similar Documents

Publication Publication Date Title
IN2012DN00338A (hu)
MX2009007632A (es) Precipitacion de polielectrolito y purificacion de proteinas.
IN2012DN00801A (hu)
TW200801262A (en) Method for purifying silicon
HK1157733A1 (en) Apparatus for purifying liquids, in particular ballast water
PL2459715T3 (pl) Sposób oczyszczania rekombinowanego adamts13 i innych białek oraz ich kompozycje
EA201070987A1 (ru) Очищенные гибридные белки иммуноглобулина и способы их очищения
BRPI0917993A2 (pt) composições de célula-tronco mesenquimal purificada e métodos de purificação de composições de célula-tronco mesenquimal purificda.
UA105785C2 (uk) Спосіб очищення ліпопептидів
EA201270616A1 (ru) Ингибиторы вируса гепатита с
GB2471806A (en) Compositions and methods for treating viral infections
MX339402B (es) Composiciones y metodos que comprenden variantes de serina proteasa.
MX342920B (es) Metodo para purificar polipeptidos o inmunoconjugados activos.
MX2012002565A (es) Purificacion de proteina mejorada a traves de una elucion de proteina a modificada.
MY188566A (en) Method to improve virus removal in protein purification
WO2011017132A3 (en) Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
WO2010039802A3 (en) Methods and compositions for isolating nucleic acid
NZ703093A (en) Purification of iduronate-2-sulfatase
UA108636C2 (xx) Пептид
WO2008085962A3 (en) Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants
MX2011008179A (es) Peptidos para vacuna.
TW200738622A (en) Process for purifying (meth)acrylates
UA103197C2 (uk) Застосування ніфуртимоксу для лікування хвороб, спричинених трихомонадами
NZ708503A (en) Purification of x-ray contrast agents
PL2286887T3 (pl) Usuwanie endotoksyn ze środków kontrastowych