IN188469B - - Google Patents
Info
- Publication number
- IN188469B IN188469B IN420DE2000A IN188469B IN 188469 B IN188469 B IN 188469B IN 420DE2000 A IN420DE2000 A IN 420DE2000A IN 188469 B IN188469 B IN 188469B
- Authority
- IN
- India
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9515379A FR2742751B1 (fr) | 1995-12-22 | 1995-12-22 | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN188469B true IN188469B (ko) | 2002-09-28 |
Family
ID=9485871
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2893DE1996 IN186768B (ko) | 1995-12-22 | 1996-12-20 | |
| IN421DE2000 IN188470B (ko) | 1995-12-22 | 2000-04-10 | |
| IN420DE2000 IN188469B (ko) | 1995-12-22 | 2000-04-10 | |
| IN419DE2000 IN188680B (ko) | 1995-12-22 | 2000-04-10 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2893DE1996 IN186768B (ko) | 1995-12-22 | 1996-12-20 | |
| IN421DE2000 IN188470B (ko) | 1995-12-22 | 2000-04-10 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN419DE2000 IN188680B (ko) | 1995-12-22 | 2000-04-10 |
Country Status (41)
| Country | Link |
|---|---|
| US (1) | US5728849A (ko) |
| EP (1) | EP0876362B1 (ko) |
| JP (1) | JP3953106B2 (ko) |
| KR (1) | KR100500351B1 (ko) |
| CN (1) | CN1103766C (ko) |
| AR (1) | AR005197A1 (ko) |
| AT (1) | ATE250593T1 (ko) |
| AU (1) | AU712597B2 (ko) |
| BG (1) | BG63204B1 (ko) |
| BR (1) | BR9612135A (ko) |
| CA (1) | CA2238884C (ko) |
| CO (1) | CO4520184A1 (ko) |
| CZ (1) | CZ294972B6 (ko) |
| DE (1) | DE69630145T2 (ko) |
| DK (1) | DK0876362T3 (ko) |
| DZ (1) | DZ2149A1 (ko) |
| EA (1) | EA001533B1 (ko) |
| ES (1) | ES2202490T3 (ko) |
| FR (1) | FR2742751B1 (ko) |
| HK (1) | HK1017895A1 (ko) |
| HU (1) | HU225032B1 (ko) |
| IL (1) | IL124994A (ko) |
| IN (4) | IN186768B (ko) |
| MA (1) | MA26412A1 (ko) |
| MX (1) | MX9804688A (ko) |
| MY (1) | MY113934A (ko) |
| NO (1) | NO317358B1 (ko) |
| NZ (1) | NZ324337A (ko) |
| OA (1) | OA10700A (ko) |
| PE (1) | PE25198A1 (ko) |
| PL (1) | PL189311B1 (ko) |
| PT (1) | PT876362E (ko) |
| RO (1) | RO116194B1 (ko) |
| SK (1) | SK282835B6 (ko) |
| TN (1) | TNSN96169A1 (ko) |
| TR (1) | TR199801179T2 (ko) |
| TW (1) | TW371659B (ko) |
| UA (1) | UA48205C2 (ko) |
| UY (1) | UY24386A1 (ko) |
| WO (1) | WO1997023473A1 (ko) |
| ZA (1) | ZA9610737B (ko) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9920548D0 (en) * | 1999-08-31 | 1999-11-03 | Rhone Poulenc Rorer Sa | Treatment of hepatocellular carcinoma |
| RO121269B1 (ro) | 2000-02-02 | 2007-02-28 | Florida State University Research Foundation, Inc. | Taxani substituiţi cu carbonat la c10, folosiţica agenţi antitumorali |
| DK1368349T3 (da) * | 2001-02-24 | 2007-05-21 | Boehringer Ingelheim Pharma | Xanthinderivater, deres fremstilling og deres anvendelse som lægemidler |
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| WO2004103344A1 (en) * | 2003-05-20 | 2004-12-02 | Aronex Pharmaceuticals, Inc. | Combination chemotherapy comprising a liposomal platinum complex |
| US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| EP1669358A1 (en) * | 2004-12-07 | 2006-06-14 | Aventis Pharma S.A. | Cytotoxic agents comprising new taxanes |
| DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| CN107235980A (zh) | 2006-05-04 | 2017-10-10 | 勃林格殷格翰国际有限公司 | 多晶型 |
| US20080207743A1 (en) * | 2007-02-28 | 2008-08-28 | Rodger Lamb | Biologically Active Taxane Analogs and Methods of Treatment |
| MX2010001821A (es) * | 2007-08-17 | 2010-03-10 | Boehringer Ingelheim Int | Derivados de purina para uso en el tratamiento de enfermedades relacionadas con fap. |
| AR071175A1 (es) | 2008-04-03 | 2010-06-02 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante |
| PE20100156A1 (es) * | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | Tratamiento de nafld |
| KR20190016601A (ko) | 2008-08-06 | 2019-02-18 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| US8513264B2 (en) | 2008-09-10 | 2013-08-20 | Boehringer Ingelheim International Gmbh | Combination therapy for the treatment of diabetes and related conditions |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| JP2012512848A (ja) | 2008-12-23 | 2012-06-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 有機化合物の塩の形態 |
| AR074990A1 (es) | 2009-01-07 | 2011-03-02 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina |
| UY32048A (es) * | 2009-01-08 | 2010-03-26 | Boehringer Ingelheim Int | Derivados sustituido de 1-(sustituido)-3-metil-7-(sustituido)-8-(3-(R)-amino-piperidin-1-il)cantina y derivados sustituidos de 1-(sustituido) - 4 - fluoropirrolidin- 2 - carbonitrilo y sus sales famacéuticamente aceptables como inhibidores de DPP-4 y aplicaciones. |
| ES2760917T3 (es) | 2009-11-27 | 2020-05-18 | Boehringer Ingelheim Int | Tratamiento de pacientes diabéticos genotipificados con inhibidores DPP-IV como la linagliptina |
| BR112012028136A2 (pt) | 2010-05-05 | 2016-08-09 | Boehringer Ingelheim Int | terapia de combinaçao |
| ES2953123T3 (es) | 2010-06-24 | 2023-11-08 | Boehringer Ingelheim Int | Terapia para la diabetes |
| US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
| ES2713566T3 (es) | 2011-07-15 | 2019-05-22 | Boehringer Ingelheim Int | Derivado de quinazolina dimérico sustituido, su preparación y su uso en composiciones farmacéuticas para el tratamiento de la diabetes de tipo I y II |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| WO2013171167A1 (en) | 2012-05-14 | 2013-11-21 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| JP6133431B2 (ja) | 2012-11-24 | 2017-05-24 | ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． | 親水性連結体及び薬物分子と細胞結合分子との共役反応における親水性連結体の使用 |
| FR3010839B1 (fr) * | 2013-09-17 | 2017-04-21 | Schneider Electric Ind Sas | Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique |
| ES2950384T3 (es) | 2014-02-28 | 2023-10-09 | Boehringer Ingelheim Int | Uso médico de un inhibidor de DPP-4 |
| JP6417421B2 (ja) | 2014-02-28 | 2018-11-07 | ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． | 荷電連結体及び共役体のためのその使用 |
| CN113350518A (zh) | 2015-07-12 | 2021-09-07 | 杭州多禧生物科技有限公司 | 与细胞结合分子的共轭偶联的桥连接体 |
| US9839687B2 (en) | 2015-07-15 | 2017-12-12 | Suzhou M-Conj Biotech Co., Ltd. | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule |
| WO2017211979A1 (en) | 2016-06-10 | 2017-12-14 | Boehringer Ingelheim International Gmbh | Combinations of linagliptin and metformin |
| EP3538080A4 (en) | 2016-11-14 | 2020-07-08 | Hangzhou Dac Biotech Co., Ltd. | CONJUGATION LINERS, MEDICAMENT-MOLECULE CONJUGATES TO A CELL CONTAINING THE SAME, METHODS OF PREPARING AND USING SUCH CONJUGATES WITH THE BINDERS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2017724C1 (ru) * | 1990-07-12 | 1994-08-15 | Дзе Юниверсити оф Канзас | Способ получения производных таксола |
| US5059699A (en) * | 1990-08-28 | 1991-10-22 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
| FR2678930B1 (fr) * | 1991-07-10 | 1995-01-13 | Rhone Poulenc Rorer Sa | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii. |
| RU2059631C1 (ru) * | 1991-11-29 | 1996-05-10 | Дзе Юниверсити оф Канзас | Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью |
| WO1993021173A1 (en) * | 1992-04-17 | 1993-10-28 | Abbott Laboratories | Taxol derivatives |
| US5254580A (en) * | 1993-01-19 | 1993-10-19 | Bristol-Myers Squibb Company | 7,8-cyclopropataxanes |
| MX9307777A (es) * | 1992-12-15 | 1994-07-29 | Upjohn Co | 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. |
-
1995
- 1995-12-22 FR FR9515379A patent/FR2742751B1/fr not_active Expired - Fee Related
-
1996
- 1996-12-04 PE PE1996000871A patent/PE25198A1/es not_active Application Discontinuation
- 1996-12-18 MA MA24431A patent/MA26412A1/fr unknown
- 1996-12-19 EA EA199800588A patent/EA001533B1/ru not_active IP Right Cessation
- 1996-12-19 WO PCT/FR1996/002031 patent/WO1997023473A1/fr active IP Right Grant
- 1996-12-19 AT AT96942433T patent/ATE250593T1/de active
- 1996-12-19 UA UA98063216A patent/UA48205C2/uk unknown
- 1996-12-19 DK DK96942433T patent/DK0876362T3/da active
- 1996-12-19 ZA ZA9610737A patent/ZA9610737B/xx unknown
- 1996-12-19 NZ NZ324337A patent/NZ324337A/xx not_active IP Right Cessation
- 1996-12-19 ES ES96942433T patent/ES2202490T3/es not_active Expired - Lifetime
- 1996-12-19 DE DE69630145T patent/DE69630145T2/de not_active Expired - Lifetime
- 1996-12-19 BR BR9612135A patent/BR9612135A/pt not_active IP Right Cessation
- 1996-12-19 TW TW085115683A patent/TW371659B/zh not_active IP Right Cessation
- 1996-12-19 CA CA002238884A patent/CA2238884C/fr not_active Expired - Fee Related
- 1996-12-19 KR KR10-1998-0704792A patent/KR100500351B1/ko not_active IP Right Cessation
- 1996-12-19 TR TR1998/01179T patent/TR199801179T2/xx unknown
- 1996-12-19 EP EP96942433A patent/EP0876362B1/fr not_active Expired - Lifetime
- 1996-12-19 SK SK853-98A patent/SK282835B6/sk not_active IP Right Cessation
- 1996-12-19 AU AU11809/97A patent/AU712597B2/en not_active Ceased
- 1996-12-19 CZ CZ19981961A patent/CZ294972B6/cs not_active IP Right Cessation
- 1996-12-19 JP JP52336197A patent/JP3953106B2/ja not_active Expired - Fee Related
- 1996-12-19 PT PT96942433T patent/PT876362E/pt unknown
- 1996-12-19 IL IL12499496A patent/IL124994A/xx not_active IP Right Cessation
- 1996-12-19 PL PL96327405A patent/PL189311B1/pl not_active IP Right Cessation
- 1996-12-19 HU HU9904046A patent/HU225032B1/hu not_active IP Right Cessation
- 1996-12-19 RO RO98-01093A patent/RO116194B1/ro unknown
- 1996-12-19 CN CN96199168A patent/CN1103766C/zh not_active Expired - Fee Related
- 1996-12-20 MY MYPI96005421A patent/MY113934A/en unknown
- 1996-12-20 CO CO96067023A patent/CO4520184A1/es unknown
- 1996-12-20 AR ARP960105851A patent/AR005197A1/es active IP Right Grant
- 1996-12-20 TN TNTNSN96169A patent/TNSN96169A1/fr unknown
- 1996-12-20 US US08/771,751 patent/US5728849A/en not_active Expired - Lifetime
- 1996-12-20 IN IN2893DE1996 patent/IN186768B/en unknown
- 1996-12-21 DZ DZ960194A patent/DZ2149A1/fr active
-
1998
- 1998-06-05 NO NO19982580A patent/NO317358B1/no not_active IP Right Cessation
- 1998-06-11 MX MX9804688A patent/MX9804688A/es not_active IP Right Cessation
- 1998-06-19 OA OA9800087A patent/OA10700A/fr unknown
- 1998-06-22 BG BG102569A patent/BG63204B1/bg unknown
-
1999
- 1999-07-13 HK HK99102999A patent/HK1017895A1/xx not_active IP Right Cessation
-
2000
- 2000-04-10 IN IN421DE2000 patent/IN188470B/en unknown
- 2000-04-10 IN IN420DE2000 patent/IN188469B/en unknown
- 2000-04-10 IN IN419DE2000 patent/IN188680B/en unknown
- 2000-12-02 UY UY24386A patent/UY24386A1/es unknown