IL98920A - Carbamates converted to 1- (pyridinylaminomers) (H1-indole-5-yl), a method and materials for their preparation and use as drugs - Google Patents
Carbamates converted to 1- (pyridinylaminomers) (H1-indole-5-yl), a method and materials for their preparation and use as drugsInfo
- Publication number
- IL98920A IL98920A IL9892091A IL9892091A IL98920A IL 98920 A IL98920 A IL 98920A IL 9892091 A IL9892091 A IL 9892091A IL 9892091 A IL9892091 A IL 9892091A IL 98920 A IL98920 A IL 98920A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- hydrogen
- formula
- loweralkyi
- indol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/555,890 US5102891A (en) | 1990-07-23 | 1990-07-23 | 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates |
Publications (1)
Publication Number | Publication Date |
---|---|
IL98920A true IL98920A (en) | 1995-08-31 |
Family
ID=24218998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9892091A IL98920A (en) | 1990-07-23 | 1991-07-22 | Carbamates converted to 1- (pyridinylaminomers) (H1-indole-5-yl), a method and materials for their preparation and use as drugs |
Country Status (23)
Country | Link |
---|---|
US (1) | US5102891A (ja) |
EP (1) | EP0468401B1 (ja) |
JP (1) | JP2564714B2 (ja) |
KR (1) | KR100201515B1 (ja) |
AT (1) | ATE171176T1 (ja) |
AU (1) | AU639581B2 (ja) |
BR (1) | BR1100534A (ja) |
CA (1) | CA2047531C (ja) |
CZ (1) | CZ283253B6 (ja) |
DE (1) | DE69130196T2 (ja) |
DK (1) | DK0468401T3 (ja) |
ES (1) | ES2121761T3 (ja) |
FI (1) | FI102067B (ja) |
HU (1) | HUT58317A (ja) |
IE (1) | IE912567A1 (ja) |
IL (1) | IL98920A (ja) |
MX (1) | MX9100342A (ja) |
NO (1) | NO300132B1 (ja) |
NZ (1) | NZ239038A (ja) |
PL (1) | PL291185A1 (ja) |
PT (1) | PT98413B (ja) |
SG (1) | SG48059A1 (ja) |
ZA (1) | ZA915723B (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5264442A (en) * | 1990-08-13 | 1993-11-23 | Hoechst-Roussel Pharmaceuticals Incorporated | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs |
CZ284437B6 (cs) * | 1991-04-17 | 1998-11-11 | Hoechst Marion Roussel, Inc. | Substituované (pyridinylamino)-benzisoxazoly a -benzo[b]thiofeny, způsob jejich přípravy farmaceutický prostředek obsahující tyto sloučeniny a použití těchto sloučenin |
US5319096A (en) * | 1992-04-03 | 1994-06-07 | Hoechst-Roussel Pharmaceuticals Inc. | (1H-indol-1-yl)-2-(amino) acetamides and related (1H-indol-1-yl)-(aminoalkyl)amides, pharmaceutical composition and use |
US5459274A (en) * | 1994-05-13 | 1995-10-17 | Hoechst-Roussel Pharmaceuticals Inc. | Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines |
US6004977A (en) * | 1996-12-27 | 1999-12-21 | Hoechst Marion Roussel, Inc. | N-(pyridinylamino) isoindolines and related compounds |
HUP0000783A2 (hu) * | 1996-12-27 | 2001-04-28 | Hoechst Marion Roussel, Inc. | N-(piridinil-amino)-izoindolinok és származékaik, eljárás előállításukra, e vegyületeket tartalmazó gyógyszerkészítmények és alkalmazásuk |
US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
GT200500063A (es) * | 2004-04-01 | 2005-10-14 | Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias | |
FR2888238B1 (fr) * | 2005-07-07 | 2007-09-07 | Servier Lab | Nouveaux derives 1h-indole-pyridinecarboxamides et 1h-indole-piperidinecarboxamide, leur procede de preparation et les compositions pharceumatiques qui les contiennent. |
CN109662964A (zh) * | 2010-02-09 | 2019-04-23 | 约翰斯.霍普金斯大学 | 用于改善认知功能的方法和组合物 |
CA2891122C (en) | 2012-11-14 | 2021-07-20 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
AU2014228512A1 (en) | 2013-03-15 | 2015-10-01 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
CN112843005B (zh) | 2015-05-22 | 2023-02-21 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
US4970218A (en) * | 1987-04-24 | 1990-11-13 | Hoechst-Roussel Pharmaceuticals Inc. | N-(pyridinyl)-1H-indol-1-amines |
ATE115143T1 (de) * | 1987-04-24 | 1994-12-15 | Hoechst Roussel Pharma | N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel. |
US4983615A (en) * | 1989-06-28 | 1991-01-08 | Hoechst-Roussel Pharmaceuticals Inc. | Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders |
US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
US4992448A (en) * | 1989-10-24 | 1991-02-12 | Hoechst-Roussel Pharmaceuticals Inc. | Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders |
-
1990
- 1990-07-23 US US07/555,890 patent/US5102891A/en not_active Expired - Fee Related
-
1991
- 1991-07-19 FI FI913502A patent/FI102067B/fi active IP Right Grant
- 1991-07-19 NZ NZ239038A patent/NZ239038A/en unknown
- 1991-07-22 SG SG1996006744A patent/SG48059A1/en unknown
- 1991-07-22 PL PL29118591A patent/PL291185A1/xx unknown
- 1991-07-22 AT AT91112237T patent/ATE171176T1/de not_active IP Right Cessation
- 1991-07-22 ZA ZA915723A patent/ZA915723B/xx unknown
- 1991-07-22 CZ CS912281A patent/CZ283253B6/cs not_active IP Right Cessation
- 1991-07-22 PT PT98413A patent/PT98413B/pt not_active IP Right Cessation
- 1991-07-22 DK DK91112237T patent/DK0468401T3/da active
- 1991-07-22 IE IE256791A patent/IE912567A1/en not_active IP Right Cessation
- 1991-07-22 NO NO912866A patent/NO300132B1/no unknown
- 1991-07-22 CA CA002047531A patent/CA2047531C/en not_active Expired - Fee Related
- 1991-07-22 AU AU81216/91A patent/AU639581B2/en not_active Expired - Fee Related
- 1991-07-22 JP JP3181210A patent/JP2564714B2/ja not_active Expired - Fee Related
- 1991-07-22 HU HU912450A patent/HUT58317A/hu unknown
- 1991-07-22 EP EP91112237A patent/EP0468401B1/en not_active Expired - Lifetime
- 1991-07-22 IL IL9892091A patent/IL98920A/en not_active IP Right Cessation
- 1991-07-22 ES ES91112237T patent/ES2121761T3/es not_active Expired - Lifetime
- 1991-07-22 DE DE69130196T patent/DE69130196T2/de not_active Expired - Fee Related
- 1991-07-23 KR KR1019910012579A patent/KR100201515B1/ko not_active IP Right Cessation
- 1991-07-23 MX MX9100342A patent/MX9100342A/es not_active IP Right Cessation
-
1997
- 1997-04-13 BR BR1100534-3A patent/BR1100534A/pt active IP Right Grant
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC | Change of name of proprietor(s) | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |