IL93754A - Genetic unit for inhibition ANR - Google Patents
Genetic unit for inhibition ANRInfo
- Publication number
- IL93754A IL93754A IL9375490A IL9375490A IL93754A IL 93754 A IL93754 A IL 93754A IL 9375490 A IL9375490 A IL 9375490A IL 9375490 A IL9375490 A IL 9375490A IL 93754 A IL93754 A IL 93754A
- Authority
- IL
- Israel
- Prior art keywords
- rna
- dna
- dna molecule
- ribozyme
- inhibiting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/121—Hammerhead
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT60989 | 1989-03-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL93754A0 IL93754A0 (en) | 1990-12-23 |
IL93754A true IL93754A (en) | 1995-12-31 |
Family
ID=3495118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL9375490A IL93754A (en) | 1989-03-16 | 1990-03-15 | Genetic unit for inhibition ANR |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0387775B1 (fr) |
JP (1) | JP3330930B2 (fr) |
KR (1) | KR900014591A (fr) |
AT (1) | ATE140961T1 (fr) |
AU (1) | AU637354B2 (fr) |
CA (1) | CA2012312C (fr) |
DD (1) | DD297838A5 (fr) |
DE (1) | DE59010432D1 (fr) |
DK (1) | DK0387775T3 (fr) |
ES (1) | ES2090049T3 (fr) |
FI (1) | FI105103B (fr) |
GR (1) | GR3020935T3 (fr) |
HU (2) | HU215187B (fr) |
IE (1) | IE74850B1 (fr) |
IL (1) | IL93754A (fr) |
NO (1) | NO306623B1 (fr) |
NZ (1) | NZ232917A (fr) |
PT (1) | PT93440B (fr) |
RU (1) | RU2136751C1 (fr) |
ZA (1) | ZA901973B (fr) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0471796A4 (en) * | 1989-05-10 | 1993-05-05 | Sloan Kettering Institute For Cancer Research | Stably transformed eucaryotic cells comprising a foreign transcribable dna under the control of a pol iii promoter |
DE4091533T (fr) * | 1989-08-31 | 1992-01-30 | ||
JP2507895B2 (ja) * | 1989-12-19 | 1996-06-19 | 工業技術院長 | リボザイムの新規合成系 |
WO1991019789A1 (fr) * | 1990-06-19 | 1991-12-26 | Commonwealth Scientific And Industrial Research Organisation | Endonucleases |
US6008343A (en) * | 1990-06-19 | 1999-12-28 | Gene Shears Pty. Ltd. | Nucleotide based endonucleases |
DE69123979T2 (de) * | 1990-10-12 | 1997-04-30 | Max Planck Gesellschaft | Abgeänderte ribozyme |
DE4104186A1 (de) * | 1991-02-12 | 1992-08-13 | Genentech Inc | Neue, ueber endozytose in hoehere eukaryotische zellen aufnehmbare, nukleinsaeure enthaltende komplexe |
FR2687411A1 (fr) * | 1992-02-13 | 1993-08-20 | Nice Sophia Antipolis Universi | Vecteur comportant un gene viral transcrit par l'arn polymerase iii, et procede de production intracellulaire d'arn. |
WO1993022433A2 (fr) * | 1992-04-28 | 1993-11-11 | Frank Andreas Harald Meyer | Medicament permettant de traiter l'homme, les animaux et les plantes par therapie genetique, dans le but notamment de bloquer la proliferation de virus et les carcinogenes et procede de fabrication dudit medicament |
EP0641212A4 (fr) * | 1992-05-14 | 1997-05-21 | Ribozyme Pharm Inc | Procede et reactif destines a empecher l'evolution du cancer. |
US5610052A (en) * | 1992-08-26 | 1997-03-11 | Ribozyme Pharmaceuticals Inc. | Enzymatic RNA with activity to ras |
US5989906A (en) * | 1992-05-14 | 1999-11-23 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for inhibiting P-glycoprotein (mdr-1-gene) |
WO1993024133A1 (fr) * | 1992-05-27 | 1993-12-09 | City Of Hope | MOLECULES CHIMERIQUES DE RIBOZYMES D'ARNt?LYS¿ |
US5827935A (en) * | 1992-05-27 | 1998-10-27 | City Of Hope | Chimeric tRNAlys -ribozyme molecules |
DE69333937T2 (de) * | 1992-06-29 | 2006-08-31 | Gene Shears Pty. Ltd. | Nukleinsäuren und sie verwendende verfahren zur bekämpfung viraler pathogene |
WO1994013798A1 (fr) * | 1992-12-16 | 1994-06-23 | Bergmann Johanna E | Agents destines a la prophylaxie et au traitement de la maladie d'alzheimer chez l'homme |
EP0647716B1 (fr) * | 1993-07-06 | 2003-09-24 | Universite De Nice-Sophia Antipolis | Vecteur comportant un gène viral transcrit par l'ARN polymérase III |
US5837503A (en) * | 1993-07-07 | 1998-11-17 | Universite De Nice-Sophia-Antipolis | Vector containing viral gene transcribed by RNA polymerase III and methods for use |
US5817635A (en) * | 1993-08-09 | 1998-10-06 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Modified ribozymes |
EP0707493A4 (fr) * | 1994-01-24 | 1999-03-31 | Hope City | Co-localisation d'une molecule cible et de ses inhibiteurs |
DE4424761C1 (de) * | 1994-07-04 | 1995-06-08 | Max Planck Gesellschaft | Expressionskassette für die Antisense- und die Ribozym-Expression |
JPH11506914A (ja) | 1995-06-07 | 1999-06-22 | コモンウェルス・サイエンティフィック・アンド・インダストリアル・リサーチ・オーガニゼーション | 最適化ミニザイムおよびミニリボザイムおよびその使用 |
FR2755976B1 (fr) | 1996-11-15 | 1999-01-15 | Idm Immuno Designed Molecules | Nouveaux complexes d'acides nucleiques et de polymere substitue par des residus entrainant la destabilisation des membranes cellulaires |
US6057156A (en) | 1997-01-31 | 2000-05-02 | Robozyme Pharmaceuticals, Inc. | Enzymatic nucleic acid treatment of diseases or conditions related to levels of epidermal growth factor receptors |
AU1187099A (en) * | 1997-10-21 | 1999-05-10 | Ribozyme Pharmaceuticals, Inc. | Peptide bond formation using nucleic acid catalysts |
US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
CN101818145A (zh) | 1998-03-20 | 2010-09-01 | 联邦科学和工业研究组织 | 控制基因表达 |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
EP1147204A1 (fr) | 1999-01-28 | 2001-10-24 | Medical College Of Georgia Research Institute, Inc. | Composition et methode destinees a l'attenuation in vivo et in vitro de l'expression genique utilisant de l'arn double brin |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
EP1229134A3 (fr) | 2001-01-31 | 2004-01-28 | Nucleonics, Inc | Utilisation de l'inhibition post-transcriptionnelle pour l'identification des séquences d'acides nucléiques qui modifient la fonction d'une cellule |
AUPR621501A0 (en) | 2001-07-06 | 2001-08-02 | Commonwealth Scientific And Industrial Research Organisation | Delivery of ds rna |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4987071A (en) * | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
-
1990
- 1990-03-13 DK DK90104701.9T patent/DK0387775T3/da active
- 1990-03-13 AT AT90104701T patent/ATE140961T1/de not_active IP Right Cessation
- 1990-03-13 EP EP90104701A patent/EP0387775B1/fr not_active Expired - Lifetime
- 1990-03-13 ES ES90104701T patent/ES2090049T3/es not_active Expired - Lifetime
- 1990-03-13 DE DE59010432T patent/DE59010432D1/de not_active Expired - Lifetime
- 1990-03-14 HU HU901584A patent/HU215187B/hu unknown
- 1990-03-14 NZ NZ232917A patent/NZ232917A/en unknown
- 1990-03-14 DD DD90338709A patent/DD297838A5/de not_active IP Right Cessation
- 1990-03-15 PT PT93440A patent/PT93440B/pt not_active IP Right Cessation
- 1990-03-15 IL IL9375490A patent/IL93754A/en not_active IP Right Cessation
- 1990-03-15 NO NO901213A patent/NO306623B1/no not_active IP Right Cessation
- 1990-03-15 AU AU51301/90A patent/AU637354B2/en not_active Expired
- 1990-03-15 KR KR1019900003438A patent/KR900014591A/ko not_active Application Discontinuation
- 1990-03-15 CA CA002012312A patent/CA2012312C/fr not_active Expired - Lifetime
- 1990-03-15 FI FI901296A patent/FI105103B/fi active IP Right Grant
- 1990-03-15 JP JP06549390A patent/JP3330930B2/ja not_active Expired - Lifetime
- 1990-03-15 IE IE93190A patent/IE74850B1/en not_active IP Right Cessation
- 1990-03-15 ZA ZA901973A patent/ZA901973B/xx unknown
- 1990-03-16 RU SU5010032A patent/RU2136751C1/ru active
-
1995
- 1995-06-30 HU HU95P/P00692P patent/HU211868A9/hu unknown
-
1996
- 1996-09-03 GR GR960402292T patent/GR3020935T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
PT93440A (pt) | 1990-11-07 |
IE74850B1 (en) | 1997-08-13 |
CA2012312A1 (fr) | 1990-09-16 |
IL93754A0 (en) | 1990-12-23 |
ZA901973B (en) | 1991-11-27 |
NO901213D0 (no) | 1990-03-15 |
EP0387775A1 (fr) | 1990-09-19 |
NZ232917A (en) | 1997-07-27 |
IE900931L (en) | 1990-09-16 |
AU5130190A (en) | 1990-11-01 |
FI901296A0 (fi) | 1990-03-15 |
HU215187B (hu) | 1998-10-28 |
DE59010432D1 (de) | 1996-09-05 |
EP0387775B1 (fr) | 1996-07-31 |
DK0387775T3 (da) | 1996-11-04 |
HU901584D0 (en) | 1990-06-28 |
HU211868A9 (en) | 1995-12-28 |
AU637354B2 (en) | 1993-05-27 |
ATE140961T1 (de) | 1996-08-15 |
PT93440B (pt) | 2001-07-31 |
RU2136751C1 (ru) | 1999-09-10 |
KR900014591A (ko) | 1990-10-24 |
NO306623B1 (no) | 1999-11-29 |
DD297838A5 (de) | 1992-01-23 |
JPH03130080A (ja) | 1991-06-03 |
GR3020935T3 (en) | 1996-12-31 |
FI105103B (fi) | 2000-06-15 |
JP3330930B2 (ja) | 2002-10-07 |
ES2090049T3 (es) | 1996-10-16 |
HUT54206A (en) | 1991-01-28 |
CA2012312C (fr) | 2001-08-14 |
NO901213L (no) | 1990-09-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2012312C (fr) | Unites genetiques pour inhiber la fonction de l'arn | |
JP3316216B2 (ja) | 安定化外部ガイド配列 | |
Koeller et al. | A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA. | |
US5874414A (en) | Trans-splicing ribozymes | |
US5354844A (en) | Protein-polycation conjugates | |
US5989906A (en) | Method and reagent for inhibiting P-glycoprotein (mdr-1-gene) | |
US5667969A (en) | Alteration of sequence of a deleterious target molecule by ribozyme catalyzed trans-splicing | |
US5750390A (en) | Method and reagent for treatment of diseases caused by expression of the bcl-2 gene | |
CA2135499A1 (fr) | Methode et reagent pour l'inhibition de la cancerogenese | |
JPH10500309A (ja) | リボザイムを用いて再狭窄および癌を治療するための方法および組成物 | |
US6183959B1 (en) | Method for target site selection and discovery | |
CA2148368A1 (fr) | Ribozymes tnf-.alpha. et derives mrna resistant a la degradation lies a ces ribozymes | |
US5599704A (en) | ErbB2/neu targeted ribozymes | |
US6830923B1 (en) | Genetics units for inhibiting the function of RNA | |
US20040072783A1 (en) | Nucleozymes with endonuclease activity | |
Phylactou et al. | Utilization of properties of natural catalytic RNA to design and synthesize functional ribozymes | |
Qiu | Cellular ribonucleases and the design of hammerhead ribozymes | |
IE83273B1 (en) | New protein-polycation-conjugates |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |