IL88107A - Aminomethyloxo- oxazolidinyl ethenylbenzene derivatives, their preparation and antibacterial compositions containing them - Google Patents

Aminomethyloxo- oxazolidinyl ethenylbenzene derivatives, their preparation and antibacterial compositions containing them

Info

Publication number
IL88107A
IL88107A IL88107A IL8810788A IL88107A IL 88107 A IL88107 A IL 88107A IL 88107 A IL88107 A IL 88107A IL 8810788 A IL8810788 A IL 8810788A IL 88107 A IL88107 A IL 88107A
Authority
IL
Israel
Prior art keywords
ethenylbenzene
derivatives
aminomethyloxo
oxazolidinyl
preparation
Prior art date
Application number
IL88107A
Other languages
English (en)
Other versions
IL88107A0 (en
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of IL88107A0 publication Critical patent/IL88107A0/xx
Publication of IL88107A publication Critical patent/IL88107A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL88107A 1987-10-21 1988-10-20 Aminomethyloxo- oxazolidinyl ethenylbenzene derivatives, their preparation and antibacterial compositions containing them IL88107A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11083787A 1987-10-21 1987-10-21

Publications (2)

Publication Number Publication Date
IL88107A0 IL88107A0 (en) 1989-06-30
IL88107A true IL88107A (en) 1993-02-21

Family

ID=22335197

Family Applications (1)

Application Number Title Priority Date Filing Date
IL88107A IL88107A (en) 1987-10-21 1988-10-20 Aminomethyloxo- oxazolidinyl ethenylbenzene derivatives, their preparation and antibacterial compositions containing them

Country Status (18)

Country Link
EP (1) EP0316594B1 (xx)
JP (1) JPH01135777A (xx)
KR (1) KR890006603A (xx)
AT (1) ATE95176T1 (xx)
AU (1) AU617697B2 (xx)
CA (1) CA1317594C (xx)
DE (1) DE3884563T2 (xx)
DK (1) DK584188A (xx)
ES (1) ES2059467T3 (xx)
FI (1) FI884849A (xx)
HU (1) HU201915B (xx)
IL (1) IL88107A (xx)
MY (1) MY103433A (xx)
NO (1) NO884676L (xx)
NZ (1) NZ226631A (xx)
PT (1) PT88811B (xx)
RU (1) RU1801109C (xx)
ZA (1) ZA887853B (xx)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036093A (en) * 1987-10-09 1991-07-30 Du Pont Merck Pharmaceutical Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents
US5032605A (en) * 1987-10-09 1991-07-16 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
US5231188A (en) * 1989-11-17 1993-07-27 The Upjohn Company Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents
EP0610265B1 (en) * 1991-11-01 1996-12-27 PHARMACIA & UPJOHN COMPANY Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
TW299332B (xx) * 1992-12-08 1997-03-01 Upjohn Co
HUT74099A (en) * 1992-12-08 1996-11-28 Upjohn Co Tropone-substituted phenyloxazolidinone antibacterial agents and pharmaceutical compositions containing the same
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
EP0730591B1 (en) * 1993-11-22 1999-07-14 PHARMACIA & UPJOHN COMPANY Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
CZ291847B6 (cs) * 1994-10-26 2003-06-18 Pharmacia Upjohn Company Antimikrobiální fenyloxazolidinony
RU2128660C1 (ru) * 1994-11-15 1999-04-10 Фармация Энд Апджон Компани Бициклические оксазин- или тиазин-оксазолидиноны или их фармацевтически приемлемые соли и способы лечения микробных инфекций
PL185872B1 (pl) * 1995-02-03 2003-08-29 Upjohn Co Nowe podstawione fenylooksazolidynonyNowe podstawione fenylooksazolidynony
DE69614847T2 (de) * 1995-05-11 2002-04-04 Pharmacia & Upjohn Co., Kalamazoo Spirocyclische und bicyclische diazinyl- und carbazinyloxazolidinone
US5883093A (en) * 1995-09-12 1999-03-16 Pharmacia & Upjohn Company Phenyloxazolidinone antimicrobials
GB9702213D0 (en) * 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
ES2315435T3 (es) 1996-08-12 2009-04-01 Celgene Corporation Nuevos agentes inmunoterapeuticos y su uso para la reduccion de los niveles de citoquinas.
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) * 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
EP1030852B1 (en) * 1997-11-12 2003-09-17 PHARMACIA & UPJOHN COMPANY Oxazolidinone derivatives and pharmaceutical compositions
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
NZ505902A (en) * 1998-01-23 2003-08-29 Upjohn Co Oxazolidinone compounds useful as antimicrobial agents and combinatorial libraries
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
AU773359B2 (en) 1999-07-28 2004-05-20 Pharmacia & Upjohn Company Oxazolidinones and their use as antiinfectives
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
WO2002018354A1 (en) * 2000-08-31 2002-03-07 Abbott Laboratories Oxazolidinones and their use as antibacterial agents
WO2002020515A1 (en) * 2000-09-08 2002-03-14 Abbott Laboratories Oxazolidinone antibacterial agents
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
US7125568B2 (en) 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
US7470723B2 (en) 2003-03-05 2008-12-30 Celgene Corporation Diphenylethylene compounds and uses thereof
EP1603864A4 (en) 2003-03-05 2007-04-11 Celgene Corp DIPHENYLETHYLENE COMPOUNDS AND THEIR USE
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
CN101052630A (zh) 2004-09-03 2007-10-10 细胞基因公司 取代的杂环化合物和其用途
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005045518A1 (de) 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
BRPI0616801B8 (pt) 2005-10-04 2021-05-25 Bayer Healthcare Ag "forma polimórfica de 5-cloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morfolinil)-fenil]-1,3-oxazolidin-5-il}-metil)-2-tiofenocarboxamida, seus processos de preparação e seus usos, medicamento, e processo para prevenção de coagulação de sangue in vitro
JP5613656B2 (ja) 2008-03-26 2014-10-29 グローバル、アライアンス、フォア、ティービー、ドラッグ、ディベロップメント 置換されたフェニルオキサゾリジノンと共有結合した二環式ニトロイミダゾール
EP3498273A1 (en) * 2017-12-14 2019-06-19 Universität Wien Pharmaceutical composition for modulating the response of a gaba-a receptor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1222708A (en) * 1968-10-22 1971-02-17 Delalande Sa Novel 5-(n-substituted aminomethyl)-2-oxazolidinones and their process of preparation
FR2500450A1 (fr) * 1981-02-25 1982-08-27 Delalande Sa Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
ES533097A0 (es) * 1983-06-07 1985-08-01 Du Pont Un procedimiento para la preparacion de nuevos derivados del amino-metil-oxooxazolidinil-benzeno.
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents

Also Published As

Publication number Publication date
AU617697B2 (en) 1991-12-05
AU2404388A (en) 1989-04-27
FI884849A (fi) 1989-04-22
ES2059467T3 (es) 1994-11-16
NO884676L (no) 1989-04-24
ZA887853B (en) 1990-06-27
ATE95176T1 (de) 1993-10-15
FI884849A0 (fi) 1988-10-20
IL88107A0 (en) 1989-06-30
RU1801109C (ru) 1993-03-07
HU201915B (en) 1991-01-28
PT88811B (pt) 1993-04-30
HUT52075A (en) 1990-06-28
EP0316594B1 (en) 1993-09-29
MY103433A (en) 1993-06-30
KR890006603A (ko) 1989-06-14
JPH01135777A (ja) 1989-05-29
DE3884563D1 (de) 1993-11-04
DK584188A (da) 1989-04-22
DE3884563T2 (de) 1994-02-17
EP0316594A1 (en) 1989-05-24
NZ226631A (en) 1991-01-29
NO884676D0 (no) 1988-10-20
CA1317594C (en) 1993-05-11
DK584188D0 (da) 1988-10-20

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Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force