IL87586A - 3(-demethoxypipo- dophyllotoxin glucoside derivatives and pharmaceutical compositions containing them - Google Patents

3(-demethoxypipo- dophyllotoxin glucoside derivatives and pharmaceutical compositions containing them

Info

Publication number: IL87586A
Authority: IL; Israel
Prior art keywords: dophyllotoxin; demethoxypipo; pharmaceutical compositions; compositions containing; glucoside derivatives
Prior art date: 1987-08-31

Application number

IL87586A

Other languages

English (en)

Other versions

IL87586A0 (en

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-31

Filing date

1988-08-29

Publication date

1993-07-08

1988-08-29 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

1989-01-31 Publication of IL87586A0 publication Critical patent/IL87586A0/xx

1993-07-08 Publication of IL87586A publication Critical patent/IL87586A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

IL87586A 1987-08-31 1988-08-29 3(-demethoxypipo- dophyllotoxin glucoside derivatives and pharmaceutical compositions containing them IL87586A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/091,570 US4888419A (en)	1987-08-31	1987-08-31	3'-demethoxyepipodophyllotoxin glucoside derivatives

Publications (2)

Publication Number	Publication Date
IL87586A0 IL87586A0 (en)	1989-01-31
IL87586A true IL87586A (en)	1993-07-08

Family

ID=22228465

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL87586A IL87586A (en)	1987-08-31	1988-08-29	3(-demethoxypipo- dophyllotoxin glucoside derivatives and pharmaceutical compositions containing them

Country Status (13)

Country	Link
US (1)	US4888419A (xx)
EP (1)	EP0305972A3 (xx)
JP (1)	JPS6471898A (xx)
KR (1)	KR900006236B1 (xx)
AU (1)	AU620561B2 (xx)
CA (1)	CA1311472C (xx)
DK (1)	DK482488A (xx)
FI (1)	FI88168C (xx)
IL (1)	IL87586A (xx)
NO (1)	NO168040C (xx)
NZ (1)	NZ225879A (xx)
PT (1)	PT88375B (xx)
ZA (1)	ZA883763B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4853467A (en) *	1987-05-19	1989-08-01	Bristol-Myers Company	Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4965348A (en) *	1989-05-19	1990-10-23	Bristol-Myers Company	Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) *	1989-06-07	1991-07-30	Bristol-Myers Company	Acylated derivatives of etoposide
US5081234A (en) *	1990-04-30	1992-01-14	Bristol-Myers Squibb Co.	4'-demethylepipodophyllotoxin glycosides
US5459248A (en) *	1993-11-04	1995-10-17	Bristol-Myers Squibb Company	Process of preparing etoposide phosphate and etoposide
US6207673B1 (en)	1997-03-12	2001-03-27	The University Of North Carolina At Chapel Hill	Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6051721A (en) *	1997-10-02	2000-04-18	The Board Of Regents Of The University Of Nebraska	Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
EP2289549A3 (en)	1999-10-01	2011-06-15	Immunogen, Inc.	Immunoconjugates for treating cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US608815A (en) *		1898-08-09		Wagon-pole coupling
GB823068A (en) *	1955-05-13	1959-11-04	Sandoz Ltd	Condensation products from glucosides
NL6613143A (xx) *	1965-09-21	1967-03-22
FR1518705A (fr) *	1965-12-14	1968-03-29	Sandoz Sa	Procédé de préparation d'un nouveau glucoside
CH464957A (de) *	1965-12-14	1968-11-15	Sandoz Ag	Verfahren zur Herstellung eines neuen Glucosids
US4547564A (en) *	1982-12-27	1985-10-15	General Electric Company	Polyester carbonate from branched chain alkylidene dihydric phenol
JPS6032799A (ja) *	1983-07-29	1985-02-19	Microbial Chem Res Found	新規４′−デメチル−４−エピポドフィロトキシン誘導体
JPS60246393A (ja) *	1984-05-22	1985-12-06	Nippon Kayaku Co Ltd	エトポシドの新規製造法
US4609644A (en) *	1984-06-15	1986-09-02	St. Jude Children's Research Hospital	Epipodophyllotoxinquinone glucoside derivatives, method of production and use
US4853467A (en) *	1987-05-19	1989-08-01	Bristol-Myers Company	Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4874851A (en) *	1987-07-01	1989-10-17	Bristol-Meyers Company	3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives

1987
- 1987-08-31 US US07/091,570 patent/US4888419A/en not_active Expired - Fee Related
1988
- 1988-05-26 ZA ZA883763A patent/ZA883763B/xx unknown
- 1988-08-19 NZ NZ225879A patent/NZ225879A/en unknown
- 1988-08-26 FI FI883959A patent/FI88168C/fi not_active IP Right Cessation
- 1988-08-29 KR KR1019880011006A patent/KR900006236B1/ko not_active IP Right Cessation
- 1988-08-29 IL IL87586A patent/IL87586A/xx unknown
- 1988-08-30 JP JP63216197A patent/JPS6471898A/ja active Granted
- 1988-08-30 PT PT88375A patent/PT88375B/pt not_active IP Right Cessation
- 1988-08-30 EP EP88114141A patent/EP0305972A3/en not_active Withdrawn
- 1988-08-30 NO NO883857A patent/NO168040C/no unknown
- 1988-08-30 CA CA000576027A patent/CA1311472C/en not_active Expired - Fee Related
- 1988-08-30 AU AU21666/88A patent/AU620561B2/en not_active Ceased
- 1988-08-30 DK DK482488A patent/DK482488A/da unknown

Also Published As

Publication number	Publication date
AU2166688A (en)	1989-03-02
DK482488A (da)	1989-03-01
IL87586A0 (en)	1989-01-31
EP0305972A2 (en)	1989-03-08
PT88375B (pt)	1995-03-31
NZ225879A (en)	1991-04-26
FI883959A0 (fi)	1988-08-26
AU620561B2 (en)	1992-02-20
CA1311472C (en)	1992-12-15
PT88375A (pt)	1989-06-30
NO168040B (no)	1991-09-30
ZA883763B (en)	1989-10-25
US4888419A (en)	1989-12-19
FI88168C (fi)	1993-04-13
FI88168B (fi)	1992-12-31
NO883857D0 (no)	1988-08-30
KR900006236B1 (ko)	1990-08-27
FI883959A (fi)	1989-03-01
DK482488D0 (da)	1988-08-30
KR890003793A (ko)	1989-04-18
JPS6471898A (en)	1989-03-16
JPH0453877B2 (xx)	1992-08-27
NO883857L (no)	1989-03-01
EP0305972A3 (en)	1990-08-22
NO168040C (no)	1992-01-08

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