IL64033A - 1-(2,3-dihydro-1,4-benzodioxin-2s-yl)-5-(2,3-dihydro-1,4-benzodioxin-2r-yl)-3-azapentane-1r,5s-diols and salts thereof,their manufacture and pharmaceutical compositions containing them - Google Patents

1-(2,3-dihydro-1,4-benzodioxin-2s-yl)-5-(2,3-dihydro-1,4-benzodioxin-2r-yl)-3-azapentane-1r,5s-diols and salts thereof,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL64033A
IL64033A IL64033A IL6403381A IL64033A IL 64033 A IL64033 A IL 64033A IL 64033 A IL64033 A IL 64033A IL 6403381 A IL6403381 A IL 6403381A IL 64033 A IL64033 A IL 64033A
Authority
IL
Israel
Prior art keywords
benzodioxin
dihydro
azapentane
diols
salts
Prior art date
Application number
IL64033A
Other languages
English (en)
Other versions
IL64033A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL64033A0 publication Critical patent/IL64033A0/xx
Publication of IL64033A publication Critical patent/IL64033A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL64033A 1980-10-14 1981-10-12 1-(2,3-dihydro-1,4-benzodioxin-2s-yl)-5-(2,3-dihydro-1,4-benzodioxin-2r-yl)-3-azapentane-1r,5s-diols and salts thereof,their manufacture and pharmaceutical compositions containing them IL64033A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/196,503 US4313955A (en) 1980-10-14 1980-10-14 1,5-Bis(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols

Publications (2)

Publication Number Publication Date
IL64033A0 IL64033A0 (en) 1982-01-31
IL64033A true IL64033A (en) 1984-08-31

Family

ID=22725667

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64033A IL64033A (en) 1980-10-14 1981-10-12 1-(2,3-dihydro-1,4-benzodioxin-2s-yl)-5-(2,3-dihydro-1,4-benzodioxin-2r-yl)-3-azapentane-1r,5s-diols and salts thereof,their manufacture and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4313955A (es)
EP (1) EP0050585B1 (es)
JP (1) JPS5795982A (es)
KR (1) KR830007618A (es)
AR (1) AR227441A1 (es)
AT (1) ATE9694T1 (es)
AU (1) AU548164B2 (es)
DD (1) DD201678A5 (es)
DE (1) DE3166503D1 (es)
DK (1) DK454181A (es)
ES (3) ES8303403A1 (es)
FI (1) FI813154L (es)
GB (1) GB2085008B (es)
GR (1) GR75089B (es)
HU (1) HU187378B (es)
IE (1) IE51645B1 (es)
IL (1) IL64033A (es)
NO (1) NO813446L (es)
NZ (1) NZ198619A (es)
PT (1) PT73812B (es)
ZA (1) ZA817048B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4380653A (en) * 1980-10-14 1983-04-19 Ciba-Geigy Corporation 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US4471128A (en) * 1981-09-08 1984-09-11 Ciba-Geigy Corporation 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
US4654362A (en) * 1983-12-05 1987-03-31 Janssen Pharmaceutica, N.V. Derivatives of 2,2'-iminobisethanol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1038333A (en) * 1963-02-13 1966-08-10 Ici Ltd Pharmaceutical compositions
US4187313A (en) * 1978-01-30 1980-02-05 Ciba-Geigy Corporation 2-Aminoethyl-1,4-benzodioxans
US4261907A (en) * 1978-01-30 1981-04-14 Ciba-Geigy Corporation Stereospecific process
DE2827801A1 (de) * 1978-06-24 1980-01-10 Kali Chemie Pharma Gmbh Neue n tief 1 -benzoyl-n tief 2 -phenyl-1,3-diaminopropan-2-ole, verfahren zu deren herstellung und arzneimittel
US4212808A (en) * 1979-03-09 1980-07-15 Ciba-Geigy Corporation 2-Oxiranyl-1,4-benzodioxans

Also Published As

Publication number Publication date
JPS5795982A (en) 1982-06-15
ZA817048B (en) 1982-09-29
ATE9694T1 (de) 1984-10-15
GB2085008B (en) 1984-04-18
ES8600282A1 (es) 1985-10-01
EP0050585B1 (de) 1984-10-03
DK454181A (da) 1982-04-15
IE812399L (en) 1982-04-14
ES8502437A1 (es) 1985-01-01
HU187378B (en) 1985-12-28
KR830007618A (ko) 1983-11-04
GB2085008A (en) 1982-04-21
ES506212A0 (es) 1983-02-01
NZ198619A (en) 1985-07-31
PT73812A (en) 1981-11-01
AR227441A1 (es) 1982-10-29
DD201678A5 (de) 1983-08-03
DE3166503D1 (en) 1984-11-08
GR75089B (es) 1984-07-13
EP0050585A1 (de) 1982-04-28
ES516272A0 (es) 1985-01-01
AU7629081A (en) 1982-04-22
NO813446L (no) 1982-04-15
IL64033A0 (en) 1982-01-31
US4313955A (en) 1982-02-02
ES527677A0 (es) 1985-10-01
PT73812B (en) 1983-06-20
FI813154L (fi) 1982-04-15
IE51645B1 (en) 1987-01-21
ES8303403A1 (es) 1983-02-01
AU548164B2 (en) 1985-11-28

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