ZA817048B - 1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application - Google Patents

1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application

Info

Publication number
ZA817048B
ZA817048B ZA817048A ZA817048A ZA817048B ZA 817048 B ZA817048 B ZA 817048B ZA 817048 A ZA817048 A ZA 817048A ZA 817048 A ZA817048 A ZA 817048A ZA 817048 B ZA817048 B ZA 817048B
Authority
ZA
South Africa
Prior art keywords
azapentane
benzodioxin
diols
bis
compounds
Prior art date
Application number
ZA817048A
Other languages
English (en)
Inventor
Charles Ferdinand Huebner
Heinz Werner Gschwend
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA817048B publication Critical patent/ZA817048B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA817048A 1980-10-14 1981-10-13 1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application ZA817048B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/196,503 US4313955A (en) 1980-10-14 1980-10-14 1,5-Bis(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols

Publications (1)

Publication Number Publication Date
ZA817048B true ZA817048B (en) 1982-09-29

Family

ID=22725667

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA817048A ZA817048B (en) 1980-10-14 1981-10-13 1,5-bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application

Country Status (21)

Country Link
US (1) US4313955A (xx)
EP (1) EP0050585B1 (xx)
JP (1) JPS5795982A (xx)
KR (1) KR830007618A (xx)
AR (1) AR227441A1 (xx)
AT (1) ATE9694T1 (xx)
AU (1) AU548164B2 (xx)
DD (1) DD201678A5 (xx)
DE (1) DE3166503D1 (xx)
DK (1) DK454181A (xx)
ES (3) ES8303403A1 (xx)
FI (1) FI813154L (xx)
GB (1) GB2085008B (xx)
GR (1) GR75089B (xx)
HU (1) HU187378B (xx)
IE (1) IE51645B1 (xx)
IL (1) IL64033A (xx)
NO (1) NO813446L (xx)
NZ (1) NZ198619A (xx)
PT (1) PT73812B (xx)
ZA (1) ZA817048B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4380653A (en) * 1980-10-14 1983-04-19 Ciba-Geigy Corporation 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US4471128A (en) * 1981-09-08 1984-09-11 Ciba-Geigy Corporation 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
US4654362A (en) * 1983-12-05 1987-03-31 Janssen Pharmaceutica, N.V. Derivatives of 2,2'-iminobisethanol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1038333A (en) * 1963-02-13 1966-08-10 Ici Ltd Pharmaceutical compositions
US4187313A (en) * 1978-01-30 1980-02-05 Ciba-Geigy Corporation 2-Aminoethyl-1,4-benzodioxans
US4261907A (en) * 1978-01-30 1981-04-14 Ciba-Geigy Corporation Stereospecific process
DE2827801A1 (de) * 1978-06-24 1980-01-10 Kali Chemie Pharma Gmbh Neue n tief 1 -benzoyl-n tief 2 -phenyl-1,3-diaminopropan-2-ole, verfahren zu deren herstellung und arzneimittel
US4212808A (en) * 1979-03-09 1980-07-15 Ciba-Geigy Corporation 2-Oxiranyl-1,4-benzodioxans

Also Published As

Publication number Publication date
JPS5795982A (en) 1982-06-15
ATE9694T1 (de) 1984-10-15
GB2085008B (en) 1984-04-18
ES8600282A1 (es) 1985-10-01
EP0050585B1 (de) 1984-10-03
DK454181A (da) 1982-04-15
IE812399L (en) 1982-04-14
ES8502437A1 (es) 1985-01-01
HU187378B (en) 1985-12-28
KR830007618A (ko) 1983-11-04
GB2085008A (en) 1982-04-21
ES506212A0 (es) 1983-02-01
NZ198619A (en) 1985-07-31
PT73812A (en) 1981-11-01
AR227441A1 (es) 1982-10-29
DD201678A5 (de) 1983-08-03
DE3166503D1 (en) 1984-11-08
GR75089B (xx) 1984-07-13
EP0050585A1 (de) 1982-04-28
ES516272A0 (es) 1985-01-01
AU7629081A (en) 1982-04-22
NO813446L (no) 1982-04-15
IL64033A0 (en) 1982-01-31
US4313955A (en) 1982-02-02
ES527677A0 (es) 1985-10-01
IL64033A (en) 1984-08-31
PT73812B (en) 1983-06-20
FI813154L (fi) 1982-04-15
IE51645B1 (en) 1987-01-21
ES8303403A1 (es) 1983-02-01
AU548164B2 (en) 1985-11-28

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