IL49171A - 1-(indolyl-3)-alkyl)-3 or 4-(ureido or guanidino piperidines,their preparation and pharmaceutical compositions containing them - Google Patents
1-(indolyl-3)-alkyl)-3 or 4-(ureido or guanidino piperidines,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL49171A IL49171A IL49171A IL4917176A IL49171A IL 49171 A IL49171 A IL 49171A IL 49171 A IL49171 A IL 49171A IL 4917176 A IL4917176 A IL 4917176A IL 49171 A IL49171 A IL 49171A
- Authority
- IL
- Israel
- Prior art keywords
- guanidino
- piperidines
- ureido
- indolyl
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55660075A | 1975-03-10 | 1975-03-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL49171A0 IL49171A0 (en) | 1976-05-31 |
| IL49171A true IL49171A (en) | 1978-12-17 |
Family
ID=24222029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL49171A IL49171A (en) | 1975-03-10 | 1976-03-08 | 1-(indolyl-3)-alkyl)-3 or 4-(ureido or guanidino piperidines,their preparation and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4073911A (fr) |
| JP (1) | JPS51113878A (fr) |
| AU (1) | AU1175076A (fr) |
| BE (1) | BE839347A (fr) |
| DD (1) | DD124386A5 (fr) |
| DE (1) | DE2609289A1 (fr) |
| DK (1) | DK138893B (fr) |
| ES (1) | ES445874A1 (fr) |
| FI (1) | FI760584A (fr) |
| FR (1) | FR2303541A1 (fr) |
| GB (1) | GB1534351A (fr) |
| GR (1) | GR60030B (fr) |
| IL (1) | IL49171A (fr) |
| NL (1) | NL7602508A (fr) |
| NO (1) | NO760774L (fr) |
| NZ (1) | NZ180255A (fr) |
| PT (1) | PT64878B (fr) |
| SE (1) | SE7602729L (fr) |
| ZA (2) | ZA76475B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4350634A (en) | 1977-07-12 | 1982-09-21 | Sandoz Ltd. | N-Benzoyl-N'-3-indolyl-N'alkyl-1,3-diaminopropanes |
| GB1586817A (en) * | 1977-12-01 | 1981-03-25 | Wyeth John & Brother Ltd | Indole derivatives |
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| US4359468A (en) * | 1981-02-25 | 1982-11-16 | Boehringer Ingelheim Ltd. | Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones |
| NZ216720A (en) * | 1985-07-08 | 1990-09-26 | Bristol Myers Co | Diazinylpiperidine derivatives and pharmaceutical compositions |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| DE69327583T2 (de) * | 1992-03-31 | 2000-05-31 | Glaxo Group Ltd., Greenford | Substituierte phenylcarbamate und phenylharnstoffe, ihre herstellung und ihre verwendung als 5-ht4-antagonisten |
| JP3916092B2 (ja) * | 1993-09-17 | 2007-05-16 | 杏林製薬株式会社 | イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬 |
| US6489300B1 (en) * | 1997-07-31 | 2002-12-03 | Eugene D. Thorsett | Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4 |
| FR2803298A1 (fr) * | 1999-12-30 | 2001-07-06 | Adir | Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2490878C (fr) * | 2002-07-19 | 2011-03-01 | Meiji Dairies Corporation | Derives d'indole et medicaments contenant ces derives |
| WO2004091514A2 (fr) * | 2003-04-15 | 2004-10-28 | Merck & Co., Inc. | Antagonistes des recepteurs de cgrp |
| CN1842526A (zh) * | 2003-06-26 | 2006-10-04 | 麦克公司 | 苯并二氮杂䓬cgrp受体拮抗剂 |
| US7491713B2 (en) * | 2004-01-29 | 2009-02-17 | Merck + Co., Inc. | CGRP receptor antagonists |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3238215A (en) * | 1963-10-17 | 1966-03-01 | Sterling Drug Inc | 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines |
| GB1273563A (en) * | 1968-07-24 | 1972-05-10 | Wyeth John & Brother Ltd | Indoles |
-
1976
- 1976-01-28 ZA ZA760475A patent/ZA76475B/xx unknown
- 1976-02-02 US US05/654,254 patent/US4073911A/en not_active Expired - Lifetime
- 1976-02-27 SE SE7602729A patent/SE7602729L/xx unknown
- 1976-03-05 GB GB8902/76A patent/GB1534351A/en not_active Expired
- 1976-03-05 NO NO760774A patent/NO760774L/no unknown
- 1976-03-06 DE DE19762609289 patent/DE2609289A1/de active Pending
- 1976-03-06 GR GR50261A patent/GR60030B/el unknown
- 1976-03-08 IL IL49171A patent/IL49171A/xx unknown
- 1976-03-08 ES ES445874A patent/ES445874A1/es not_active Expired
- 1976-03-08 AU AU11750/76A patent/AU1175076A/en not_active Expired
- 1976-03-08 FI FI760584A patent/FI760584A/fi not_active Application Discontinuation
- 1976-03-08 FR FR7606495A patent/FR2303541A1/fr active Granted
- 1976-03-09 DD DD191763A patent/DD124386A5/xx unknown
- 1976-03-09 BE BE164977A patent/BE839347A/fr unknown
- 1976-03-09 DK DK101476AA patent/DK138893B/da unknown
- 1976-03-09 NZ NZ180255A patent/NZ180255A/xx unknown
- 1976-03-09 PT PT64878A patent/PT64878B/pt unknown
- 1976-03-09 ZA ZA761467A patent/ZA761467B/xx unknown
- 1976-03-10 JP JP51026622A patent/JPS51113878A/ja active Pending
- 1976-03-10 NL NL7602508A patent/NL7602508A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE839347A (fr) | 1976-09-09 |
| GR60030B (en) | 1978-03-31 |
| JPS51113878A (en) | 1976-10-07 |
| GB1534351A (en) | 1978-12-06 |
| FR2303541A1 (fr) | 1976-10-08 |
| NZ180255A (en) | 1978-07-10 |
| DK138893B (da) | 1978-11-13 |
| NL7602508A (nl) | 1976-09-14 |
| ZA76475B (en) | 1977-08-31 |
| PT64878B (en) | 1977-07-22 |
| ES445874A1 (es) | 1977-06-01 |
| AU1175076A (en) | 1977-09-15 |
| IL49171A0 (en) | 1976-05-31 |
| DK101476A (fr) | 1976-09-11 |
| PT64878A (en) | 1976-04-01 |
| DK138893C (fr) | 1979-04-23 |
| NO760774L (fr) | 1976-09-13 |
| FR2303541B1 (fr) | 1979-10-05 |
| SE7602729L (sv) | 1976-09-13 |
| US4073911A (en) | 1978-02-14 |
| DD124386A5 (fr) | 1977-02-16 |
| FI760584A (fr) | 1976-09-11 |
| ZA761467B (en) | 1977-10-26 |
| DE2609289A1 (de) | 1976-09-30 |
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