IL45675A - 6,8-dialkyl-7-alkoxycarbonyl-4-hydroxymethyl phthylazones and furo(3,4-f)phthalazine diones, their preparation and pharmaceutical compositions containing them - Google Patents

6,8-dialkyl-7-alkoxycarbonyl-4-hydroxymethyl phthylazones and furo(3,4-f)phthalazine diones, their preparation and pharmaceutical compositions containing them

Info

Publication number: IL45675A
Authority: IL; Israel
Prior art keywords: phthylazones; furo; alkoxycarbonyl; dialkyl; hydroxymethyl
Prior art date: 1973-10-30

Application number

IL45675A

Other languages

English (en)

Other versions

IL45675A0 (en

Original Assignee

Inoue Michiro

Shimamoto Takio

Masayuki Ishikawa

Tsuchiya Takashi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-30

Filing date

1974-09-16

Publication date

1978-10-31

1973-10-30 Priority claimed from JP12126073A external-priority patent/JPS5732065B2/ja

1973-10-31 Priority claimed from JP12175773A external-priority patent/JPS5724786B2/ja

1974-09-16 Application filed by Inoue Michiro, Shimamoto Takio, Masayuki Ishikawa, Tsuchiya Takashi filed Critical Inoue Michiro

1974-11-29 Publication of IL45675A0 publication Critical patent/IL45675A0/xx

1978-10-31 Publication of IL45675A publication Critical patent/IL45675A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL45675A 1973-10-30 1974-09-16 6,8-dialkyl-7-alkoxycarbonyl-4-hydroxymethyl phthylazones and furo(3,4-f)phthalazine diones, their preparation and pharmaceutical compositions containing them IL45675A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP12126073A JPS5732065B2 (es)	1973-10-30	1973-10-30
JP12175773A JPS5724786B2 (es)	1973-10-31	1973-10-31

Publications (2)

Publication Number	Publication Date
IL45675A0 IL45675A0 (en)	1974-11-29
IL45675A true IL45675A (en)	1978-10-31

Family

ID=26458679

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL45675A IL45675A (en)	1973-10-30	1974-09-16	6,8-dialkyl-7-alkoxycarbonyl-4-hydroxymethyl phthylazones and furo(3,4-f)phthalazine diones, their preparation and pharmaceutical compositions containing them

Country Status (20)

Country	Link
US (1)	US3963716A (es)
AR (1)	AR205004A1 (es)
CA (1)	CA1029377A (es)
CH (2)	CH611282A5 (es)
DD (1)	DD119231A5 (es)
DE (1)	DE2451417C3 (es)
DK (1)	DK134345B (es)
ES (1)	ES431454A1 (es)
FI (1)	FI59402C (es)
FR (1)	FR2248841B1 (es)
GB (1)	GB1459606A (es)
HU (1)	HU168797B (es)
IE (1)	IE39831B1 (es)
IL (1)	IL45675A (es)
IN (1)	IN139552B (es)
LU (1)	LU71191A1 (es)
NL (1)	NL7414186A (es)
PH (1)	PH10519A (es)
SE (1)	SE412389B (es)
YU (1)	YU289774A (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4120960A (en) *	1973-10-31	1978-10-17	The Boots Company Limited	Therapeutic agents
NL7702763A (nl) *	1976-03-18	1977-09-20	Takio Shimamoto En Masayuki Is	Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten.
IE47592B1 (en) *	1977-12-29	1984-05-02	Ici Ltd	Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4293553A (en) *	1978-08-11	1981-10-06	Masayuki Ishikawa	1-Phthalazone derivatives, and use thereof
US4464532A (en) *	1979-07-31	1984-08-07	Nippon Kayaku Kabushiki Kaisha	Intermediates of 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone
JPS5668609A (en) *	1979-11-07	1981-06-09	Nippon Kayaku Co Ltd	Phthalazinol preparation
JPS58116471A (ja) *	1981-12-29	1983-07-11	Nippon Kayaku Co Ltd	４−ヒドロキシメチル−１−フタラゾンエステル誘導体およびその塩
GB2127805A (en) *	1982-09-13	1984-04-18	Showa Denko Kk	Phthalazones
US4861778A (en) *	1986-06-16	1989-08-29	Research Corporation	2,3-dihydrophthalazine-1,4-diones
DE68920798T2 (de) *	1988-08-19	1995-05-18	Warner Lambert Co	Substituierte Dihydroisochinolinone und verwandte Verbindungen als Verstärker der letalen Effekte von Bestrahlung und bestimmten Chemotherapeutika; ausgewählte Verbindungen, Analoga und Verfahren.
US5177075A (en) *	1988-08-19	1993-01-05	Warner-Lambert Company	Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process
DE4333761A1 (de) *	1993-10-04	1995-04-06	Luitpold Pharma Gmbh	Heterocyclische Carbamate, Verfahren zu ihrer Herstellung und Arzneimittel
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
EP2527360B1 (en)	2007-06-04	2015-10-28	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en)	2008-06-04	2010-05-13	Synergy Pharmaceuticals, Inc.	Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US8034782B2 (en)	2008-07-16	2011-10-11	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
KR101701943B1 (ko)	2009-11-13	2017-02-02	도레이 카부시키가이샤	당뇨병의 치료 또는 예방약
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CA2828346C (en)	2011-03-01	2021-01-26	Synergy Pharmaceuticals Inc.	Process of preparing guanylate cyclase c agonists
EP3718557A3 (en)	2013-02-25	2020-10-21	Bausch Health Ireland Limited	Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing
EP2970384A1 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
CA2905435A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
EA201592263A1 (ru)	2013-06-05	2016-05-31	Синерджи Фармасьютикалз, Инк.	Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
CA2920856A1 (en)	2013-08-09	2015-02-12	Ardelyx, Inc.	Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP2022533251A (ja)	2019-05-21	2022-07-21	アルデリックス，インコーポレイテッド	患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5116430B2 (es) *	1971-08-05	1976-05-24
US3870792A (en) *	1972-07-24	1975-03-11	Michiro Inoue	Certain dihydrophthalizines for treating hemorrhage and thrombosis

1974
- 1974-01-01 AR AR256326A patent/AR205004A1/es active
- 1974-09-03 IE IE1825/74A patent/IE39831B1/en unknown
- 1974-09-04 GB GB3870874A patent/GB1459606A/en not_active Expired
- 1974-09-10 US US05/504,745 patent/US3963716A/en not_active Expired - Lifetime
- 1974-09-16 IL IL45675A patent/IL45675A/xx unknown
- 1974-10-23 FR FR7435550A patent/FR2248841B1/fr not_active Expired
- 1974-10-24 CA CA212,163A patent/CA1029377A/en not_active Expired
- 1974-10-28 SE SE7413530A patent/SE412389B/xx not_active IP Right Cessation
- 1974-10-28 DK DK561874AA patent/DK134345B/da not_active IP Right Cessation
- 1974-10-28 LU LU71191A patent/LU71191A1/xx unknown
- 1974-10-29 DE DE2451417A patent/DE2451417C3/de not_active Expired
- 1974-10-29 HU HUIO218A patent/HU168797B/hu unknown
- 1974-10-29 YU YU02897/74A patent/YU289774A/xx unknown
- 1974-10-29 ES ES431454A patent/ES431454A1/es not_active Expired
- 1974-10-29 FI FI3157/74A patent/FI59402C/fi active
- 1974-10-30 NL NL7414186A patent/NL7414186A/xx not_active Application Discontinuation
- 1974-10-30 DD DD182046A patent/DD119231A5/xx unknown
- 1974-10-30 CH CH497878A patent/CH611282A5/xx not_active IP Right Cessation
- 1974-10-30 PH PH16465A patent/PH10519A/en unknown
- 1974-10-30 CH CH1454674A patent/CH610892A5/xx not_active IP Right Cessation
1976
- 1976-02-25 IN IN330/CAL/76A patent/IN139552B/en unknown

Also Published As

Publication number	Publication date
IL45675A0 (en)	1974-11-29
SE7413530L (es)	1975-05-02
FI59402C (fi)	1981-08-10
CA1029377A (en)	1978-04-11
FI315774A (es)	1975-05-01
CH611282A5 (es)	1979-05-31
DE2451417C3 (de)	1981-01-29
DE2451417A1 (de)	1975-05-07
NL7414186A (nl)	1975-05-02
SE412389B (sv)	1980-03-03
GB1459606A (en)	1976-12-22
FR2248841B1 (es)	1978-07-28
YU289774A (en)	1983-01-21
DK561874A (es)	1975-07-07
IE39831L (en)	1975-04-30
US3963716A (en)	1976-06-15
AU7295474A (en)	1976-03-11
AR205004A1 (es)	1976-03-31
PH10519A (en)	1977-05-26
IN139552B (es)	1976-07-03
LU71191A1 (es)	1975-04-17
DK134345B (da)	1976-10-25
FI59402B (fi)	1981-04-30
FR2248841A1 (es)	1975-05-23
ES431454A1 (es)	1976-10-16
DD119231A5 (es)	1976-04-12
DK134345C (es)	1977-03-21
IE39831B1 (en)	1979-01-03
HU168797B (es)	1976-07-28
CH610892A5 (es)	1979-05-15
DE2451417B2 (de)	1980-05-14

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