IL166188A0 - Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids - Google Patents

Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids

Info

Publication number: IL166188A0
Authority: IL; Israel
Prior art keywords: phenyl; compounds; preparing substituted; cyanocyclohexanoic; acids
Prior art date: 1997-02-12

Application number

IL16618805A

Other languages

English (en)

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-02-12

Filing date

2005-01-06

Publication date

2006-01-15

2005-01-06 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2006-01-15 Publication of IL166188A0 publication Critical patent/IL166188A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/21—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Catalysts (AREA)

IL16618805A 1997-02-12 2005-01-06 Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids IL166188A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US3760897P	1997-02-12	1997-02-12
PCT/US1998/002749 WO1998034584A2 (en)	1997-02-12	1998-02-12	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids

Publications (1)

Publication Number	Publication Date
IL166188A0 true IL166188A0 (en)	2006-01-15

Family

ID=21895265

Family Applications (7)

Application Number	Title	Priority Date	Filing Date
IL13127098A IL131270A (en)	1997-02-12	1998-02-12	Compounds and method for preparing substituted 4-phenyl-4-cyanocylohexanoic acids
IL150955A IL150955A (en)	1997-02-12	2002-07-29	Compounds and Method for Preparation of Acids 4 - Phenyl - 4 - Transformed Cyanocyclohexane
IL16618405A IL166184A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
IL16618605A IL166186A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
IL16618705A IL166187A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
IL16618505A IL166185A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
IL16618805A IL166188A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids

Family Applications Before (6)

Application Number	Title	Priority Date	Filing Date
IL13127098A IL131270A (en)	1997-02-12	1998-02-12	Compounds and method for preparing substituted 4-phenyl-4-cyanocylohexanoic acids
IL150955A IL150955A (en)	1997-02-12	2002-07-29	Compounds and Method for Preparation of Acids 4 - Phenyl - 4 - Transformed Cyanocyclohexane
IL16618405A IL166184A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
IL16618605A IL166186A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
IL16618705A IL166187A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
IL16618505A IL166185A0 (en)	1997-02-12	2005-01-06	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids

Country Status (38)

Country	Link
US (1)	US6337408B1 (xx)
EP (1)	EP1023279B8 (xx)
JP (4)	JP3786971B2 (xx)
KR (1)	KR100412008B1 (xx)
CN (2)	CN1854131A (xx)
AP (1)	AP1215A (xx)
AR (2)	AR012550A1 (xx)
AT (2)	ATE300517T1 (xx)
AU (1)	AU725484B2 (xx)
BG (1)	BG63541B1 (xx)
BR (1)	BR9808637A (xx)
CA (1)	CA2279951A1 (xx)
CO (1)	CO4950534A1 (xx)
CY (1)	CY2478B1 (xx)
DE (3)	DE69831022T2 (xx)
DK (2)	DK1023279T3 (xx)
DZ (1)	DZ2423A1 (xx)
EA (1)	EA001783B1 (xx)
ES (3)	ES2246373T3 (xx)
HK (1)	HK1037613A1 (xx)
HU (1)	HUP0001801A3 (xx)
ID (1)	ID23527A (xx)
IL (7)	IL131270A (xx)
MA (1)	MA24471A1 (xx)
MY (1)	MY118813A (xx)
NO (1)	NO993863D0 (xx)
NZ (1)	NZ337084A (xx)
OA (1)	OA11144A (xx)
PL (1)	PL193366B1 (xx)
PT (2)	PT1524268E (xx)
SI (2)	SI1524268T1 (xx)
SK (1)	SK108899A3 (xx)
TR (1)	TR199901920T2 (xx)
TW (1)	TW442455B (xx)
UA (1)	UA58533C2 (xx)
UY (2)	UY24882A1 (xx)
WO (1)	WO1998034584A2 (xx)
ZA (1)	ZA981125B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA67753C2 (uk) *	1997-10-10	2004-07-15	Смітклайн Бічам Корпорейшн	Спосіб отримання заміщених 4-феніл-4-ціанциклогексанових кислот
US6452022B1 (en) *	1997-10-10	2002-09-17	Smithkline Beecham Corporation	Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
US20040220424A1 (en) *	1999-08-06	2004-11-04	Smithkline Beecham Corporation	Process for preparing acids via alpha-chloroepoxy esters
UY26268A1 (es) *	1999-08-06	2001-01-31	Smithkline Beecham Corp	Procedimiento para preparar acidos a traves de alfa-cloroep xi- esteres ley 17164 art 127
GB9920152D0 (en)	1999-08-25	1999-10-27	Smithkline Beecham Plc	Novel process
WO2001068600A2 (en)	2000-03-16	2001-09-20	Inflazyme Pharmaceuticals Limited	Benzylated pde4 inhibitors
CN102491959B (zh) *	2011-12-19	2015-03-25	江苏澄扬作物科技有限公司	一种环氧乙烷衍生物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8320943D0 (en) *	1983-08-03	1983-09-07	Lilly Industries Ltd	Organic compounds
NZ251092A (en) *	1992-04-02	1996-12-20	Smithkline Beecham Corp	4-cyano-cyclohexane derivatives; medicaments; used in treating asthma
JP3195352B2 (ja) *	1992-04-02	2001-08-06	スミスクライン・ビーチャム・コーポレイション	アレルギーおよび炎症疾患の治療用化合物

1998
- 1998-02-10 AR ARP980100587A patent/AR012550A1/es unknown
- 1998-02-10 MY MYPI98000536A patent/MY118813A/en unknown
- 1998-02-10 UY UY24882A patent/UY24882A1/es not_active IP Right Cessation
- 1998-02-11 ZA ZA981125A patent/ZA981125B/xx unknown
- 1998-02-12 AT AT02078056T patent/ATE300517T1/de not_active IP Right Cessation
- 1998-02-12 DK DK98908534T patent/DK1023279T3/da active
- 1998-02-12 KR KR10-1999-7007192A patent/KR100412008B1/ko not_active IP Right Cessation
- 1998-02-12 SI SI9830872T patent/SI1524268T1/sl unknown
- 1998-02-12 CN CNA2006100819583A patent/CN1854131A/zh active Pending
- 1998-02-12 DE DE69831022T patent/DE69831022T2/de not_active Expired - Lifetime
- 1998-02-12 MA MA24962A patent/MA24471A1/fr unknown
- 1998-02-12 AU AU66544/98A patent/AU725484B2/en not_active Ceased
- 1998-02-12 NZ NZ337084A patent/NZ337084A/en unknown
- 1998-02-12 CA CA002279951A patent/CA2279951A1/en not_active Abandoned
- 1998-02-12 CN CNB988023776A patent/CN1301982C/zh not_active Expired - Fee Related
- 1998-02-12 ES ES02078056T patent/ES2246373T3/es not_active Expired - Lifetime
- 1998-02-12 ID IDW990806A patent/ID23527A/id unknown
- 1998-02-12 AT AT98908534T patent/ATE237603T1/de not_active IP Right Cessation
- 1998-02-12 PT PT04078092T patent/PT1524268E/pt unknown
- 1998-02-12 PL PL335031A patent/PL193366B1/pl not_active IP Right Cessation
- 1998-02-12 AP APAP/P/1999/001618A patent/AP1215A/en active
- 1998-02-12 WO PCT/US1998/002749 patent/WO1998034584A2/en active IP Right Grant
- 1998-02-12 EP EP98908534A patent/EP1023279B8/en not_active Expired - Lifetime
- 1998-02-12 DZ DZ980033A patent/DZ2423A1/xx active
- 1998-02-12 ES ES98908534T patent/ES2196551T3/es not_active Expired - Lifetime
- 1998-02-12 EA EA199900735A patent/EA001783B1/ru not_active IP Right Cessation
- 1998-02-12 SK SK1088-99A patent/SK108899A3/sk unknown
- 1998-02-12 IL IL13127098A patent/IL131270A/xx not_active IP Right Cessation
- 1998-02-12 TR TR1999/01920T patent/TR199901920T2/xx unknown
- 1998-02-12 HU HU0001801A patent/HUP0001801A3/hu unknown
- 1998-02-12 DE DE69813596T patent/DE69813596T2/de not_active Expired - Lifetime
- 1998-02-12 DK DK04078092T patent/DK1524268T3/da active
- 1998-02-12 SI SI9830794T patent/SI1295869T1/sl unknown
- 1998-02-12 CO CO98007356A patent/CO4950534A1/es unknown
- 1998-02-12 BR BR9808637-5A patent/BR9808637A/pt not_active Application Discontinuation
- 1998-02-12 JP JP53506598A patent/JP3786971B2/ja not_active Expired - Fee Related
- 1998-02-12 DE DE69836928T patent/DE69836928T2/de not_active Expired - Lifetime
- 1998-02-12 ES ES04078092T patent/ES2280008T3/es not_active Expired - Lifetime
- 1998-02-12 PT PT98908534T patent/PT1023279E/pt unknown
- 1998-07-20 TW TW087101889A patent/TW442455B/zh active
- 1998-08-06 UY UY25127A patent/UY25127A1/es not_active IP Right Cessation
- 1998-12-02 UA UA99084524A patent/UA58533C2/uk unknown
1999
- 1999-08-10 BG BG103651A patent/BG63541B1/bg unknown
- 1999-08-11 NO NO993863A patent/NO993863D0/no unknown
- 1999-08-12 OA OA9900176A patent/OA11144A/en unknown
2000
- 2000-03-22 US US09/533,368 patent/US6337408B1/en not_active Expired - Fee Related
2001
- 2001-01-30 HK HK01100673A patent/HK1037613A1/xx not_active IP Right Cessation
2002
- 2002-07-29 IL IL150955A patent/IL150955A/en not_active IP Right Cessation
2004
- 2004-01-05 JP JP2004000418A patent/JP4093967B2/ja not_active Expired - Fee Related
- 2004-06-09 JP JP2004171346A patent/JP4053023B2/ja not_active Expired - Fee Related
- 2004-06-09 JP JP2004171348A patent/JP4053024B2/ja not_active Expired - Fee Related
- 2004-09-08 CY CY0400070A patent/CY2478B1/xx unknown
2005
- 2005-01-06 IL IL16618405A patent/IL166184A0/xx unknown
- 2005-01-06 IL IL16618605A patent/IL166186A0/xx unknown
- 2005-01-06 IL IL16618705A patent/IL166187A0/xx unknown
- 2005-01-06 IL IL16618505A patent/IL166185A0/xx unknown
- 2005-01-06 IL IL16618805A patent/IL166188A0/xx unknown
2006
- 2006-04-05 AR ARP060101344A patent/AR050308A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO993863L (no)	1999-08-11
BG63541B1 (bg)	2002-04-30
DK1023279T3 (da)	2003-07-21
DE69831022T2 (de)	2006-04-20
PT1023279E (pt)	2003-08-29
UA58533C2 (uk)	2003-08-15
WO1998034584A2 (en)	1998-08-13
TW442455B (en)	2001-06-23
SI1295869T1 (sl)	2005-12-31
EP1023279A2 (en)	2000-08-02
UY24882A1 (es)	2001-08-27
DE69813596D1 (de)	2003-05-22
CN1301982C (zh)	2007-02-28
ID23527A (id)	2000-04-27
KR20000070927A (ko)	2000-11-25
CN1246855A (zh)	2000-03-08
BR9808637A (pt)	2000-07-04
UY25127A1 (es)	1998-11-27
TR199901920T2 (xx)	1999-11-22
ES2280008T3 (es)	2007-09-01
PT1524268E (pt)	2007-03-30
AR012550A1 (es)	2000-11-08
IL166185A0 (en)	2006-01-15
DE69836928T2 (de)	2007-11-08
PL193366B1 (pl)	2007-02-28
NO993863D0 (no)	1999-08-11
AR050308A2 (es)	2006-10-18
EP1023279A4 (en)	2000-10-04
IL131270A0 (en)	2001-01-28
DE69836928D1 (de)	2007-03-08
MY118813A (en)	2005-01-31
HUP0001801A2 (hu)	2000-10-28
JP4053024B2 (ja)	2008-02-27
SK108899A3 (en)	2000-01-18
EP1023279B1 (en)	2003-04-16
AU725484B2 (en)	2000-10-12
JP4053023B2 (ja)	2008-02-27
HUP0001801A3 (en)	2001-12-28
JP2004149546A (ja)	2004-05-27
JP2004292460A (ja)	2004-10-21
AP9901618A0 (en)	1999-09-30
IL131270A (en)	2005-05-17
PL335031A1 (en)	2000-03-27
ZA981125B (en)	1998-08-21
DK1524268T3 (da)	2007-05-14
JP2004269546A (ja)	2004-09-30
OA11144A (en)	2003-04-17
HK1037613A1 (en)	2002-02-15
DE69831022D1 (de)	2005-09-01
IL166184A0 (en)	2006-01-15
JP4093967B2 (ja)	2008-06-04
EA001783B1 (ru)	2001-08-27
DZ2423A1 (fr)	2003-01-04
EP1023279B8 (en)	2003-08-13
BG103651A (en)	2000-02-29
KR100412008B1 (ko)	2003-12-24
CA2279951A1 (en)	1998-08-13
DE69813596T2 (de)	2004-02-12
IL150955A (en)	2006-07-05
MA24471A1 (fr)	1998-10-01
ES2246373T3 (es)	2006-02-16
AU6654498A (en)	1998-08-26
ATE237603T1 (de)	2003-05-15
CO4950534A1 (es)	2000-09-01
EA199900735A1 (ru)	2000-02-28
NZ337084A (en)	2001-04-27
CN1854131A (zh)	2006-11-01
CY2478B1 (en)	2005-06-03
WO1998034584A3 (en)	1998-11-19
JP3786971B2 (ja)	2006-06-21
ATE300517T1 (de)	2005-08-15
US6337408B1 (en)	2002-01-08
ES2196551T3 (es)	2003-12-16
IL166187A0 (en)	2006-01-15
JP2001510482A (ja)	2001-07-31
AP1215A (en)	2003-10-14
IL166186A0 (en)	2006-01-15
SI1524268T1 (sl)	2007-04-30

Publication	Publication Date	Title
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IL166188A0 (en)	2006-01-15	Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
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