IL162130A0 - Hematopoietic cells from human embryonic stem cells - Google Patents
Hematopoietic cells from human embryonic stem cellsInfo
- Publication number
- IL162130A0 IL162130A0 IL16213002A IL16213002A IL162130A0 IL 162130 A0 IL162130 A0 IL 162130A0 IL 16213002 A IL16213002 A IL 16213002A IL 16213002 A IL16213002 A IL 16213002A IL 162130 A0 IL162130 A0 IL 162130A0
- Authority
- IL
- Israel
- Prior art keywords
- cells
- embryonic stem
- human embryonic
- stem cells
- hematopoietic
- Prior art date
Links
- 210000001671 embryonic stem cell Anatomy 0.000 title 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/41—Hedgehog proteins; Cyclopamine (inhibitor)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33897901P | 2001-12-07 | 2001-12-07 | |
PCT/US2002/039091 WO2003050251A2 (en) | 2001-12-07 | 2002-12-06 | Hematopoietic cells from human embryonic stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
IL162130A0 true IL162130A0 (en) | 2005-11-20 |
Family
ID=23326944
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16213002A IL162130A0 (en) | 2001-12-07 | 2002-12-06 | Hematopoietic cells from human embryonic stem cells |
IL162130A IL162130A (en) | 2001-12-07 | 2004-05-23 | Hematopoietic cells from human embryonic stem cells |
IL200768A IL200768A (en) | 2001-12-07 | 2009-09-06 | Hematopoietic cells extracted from human embryonic stem cells |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL162130A IL162130A (en) | 2001-12-07 | 2004-05-23 | Hematopoietic cells from human embryonic stem cells |
IL200768A IL200768A (en) | 2001-12-07 | 2009-09-06 | Hematopoietic cells extracted from human embryonic stem cells |
Country Status (10)
Country | Link |
---|---|
US (1) | US20030153082A1 (xx) |
EP (2) | EP1463803B1 (xx) |
JP (4) | JP5364224B2 (xx) |
KR (3) | KR20130072272A (xx) |
CN (2) | CN102008503B (xx) |
AU (2) | AU2002366603B2 (xx) |
CA (1) | CA2469483C (xx) |
GB (2) | GB2412379B (xx) |
IL (3) | IL162130A0 (xx) |
WO (1) | WO2003050251A2 (xx) |
Families Citing this family (55)
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US7410798B2 (en) | 2001-01-10 | 2008-08-12 | Geron Corporation | Culture system for rapid expansion of human embryonic stem cells |
GB0210539D0 (en) * | 2002-05-08 | 2002-06-19 | Univ Edinburgh | Control of es cell self renewal and lineage specification, and medium therefor |
US7285415B2 (en) | 2002-07-11 | 2007-10-23 | The Regents Of The University Of California | Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury |
UA72310C2 (en) * | 2002-09-03 | 2005-02-15 | Oleksandr Leonidovy Kukharchuk | Kukharchuk-radchenko-sirman method for reinstallation of system controlling antigenic homeostasis of the body |
CN100549163C (zh) | 2002-12-16 | 2009-10-14 | 技术研究及发展基金有限公司 | 制备无饲养细胞、无异源的人胚胎干细胞的方法以及使用该方法制备的干细胞培养物 |
EP1702062A2 (en) * | 2003-06-11 | 2006-09-20 | Jan Remmereit | Differentiation of stem cells for therapeutic use |
AU2004291559B2 (en) * | 2003-11-19 | 2008-10-16 | Australian Stem Cell Centre Limited | Methods for producing blood products from pluripotent cells in cell culture |
EP1735429A4 (en) * | 2004-03-31 | 2008-06-11 | Newlink Genetics Corp | METHOD AND COMPOSITIONS FOR OBTAINING EMBRYONAL STEM CELLS OF ABSTINENT HEMATOPOETIC STEM CELLS AND USES THEREOF |
WO2006005360A1 (en) * | 2004-07-12 | 2006-01-19 | Sorin Group Italia S.R.L. | Devices and methods for growing human cells |
GB2431165B (en) | 2004-07-13 | 2009-04-01 | Geron Corp | Medium for growing human embryonic stem cells |
EP1910516B1 (en) | 2005-06-22 | 2019-06-19 | Asterias Biotherapeutics, Inc. | Suspension culture of human embryonic stem cells |
KR101529317B1 (ko) | 2005-06-22 | 2015-06-16 | 아스테리아스 바이오세라퓨틱스, 인크. | 영장류 다능성 줄기 세포의 심근세포 계통 세포로의 분화 |
EP1962719A4 (en) | 2005-08-29 | 2011-05-04 | Technion Res And Dev Of Foundation Ltd | MEDIA FOR BREEDING STEM CELLS |
JP5630781B2 (ja) * | 2006-04-14 | 2014-11-26 | アドバンスド セル テクノロジー、インコーポレイテッド | 血管コロニー形成細胞 |
DK2733203T3 (en) | 2006-08-02 | 2019-02-04 | Technion Res & Dev Foundation | PROCEDURES FOR EXPANSION OF EMBRYONAL STEM CELLS IN A SUSPENSION CULTURE |
US8058064B2 (en) | 2006-10-04 | 2011-11-15 | The University Of Tokyo | Sac-like structure enclosing hematopoietic progenitor cells produced from ES cells and method for preparing blood cells |
WO2008067142A2 (en) * | 2006-11-08 | 2008-06-05 | Wisconsin Alumni Research Foundation | In vitro differentiation of hematopoietic cells from primate embryonic stem cells |
EP2155860B1 (en) | 2007-05-03 | 2014-08-27 | The Brigham and Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
WO2009104825A1 (en) * | 2008-02-18 | 2009-08-27 | Kaist | Method for inducing the defferentiation of embryonic stem cells into hemangioblast |
EP2268794B1 (en) * | 2008-03-27 | 2017-09-13 | Asterias Biotherapeutics, Inc. | Differentiation of primate pluripotent stem cells to hematopoietic lineage cells |
JPWO2009119105A1 (ja) * | 2008-03-28 | 2011-07-21 | 国立大学法人 東京大学 | GPIbα+GPV+GPVI+血小板のインビトロ調製法 |
US8546141B2 (en) | 2008-04-01 | 2013-10-01 | The University Of Tokyo | Method for preparation of platelet from iPS cell |
KR101923290B1 (ko) | 2008-05-06 | 2018-11-28 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 혈관 콜로니 형성 세포 및 비-생착성 혈관 세포 |
JP5748654B2 (ja) | 2008-05-06 | 2015-07-15 | オカタ セラピューティクス, インコーポレイテッド | 多能性幹細胞に由来する除核赤血球細胞を産生するための方法 |
US20110171219A1 (en) * | 2008-09-19 | 2011-07-14 | Fahar Merchant | Treating cancer stem cells using targeted cargo proteins |
US8372642B2 (en) * | 2009-02-27 | 2013-02-12 | Cellular Dynamics International, Inc. | Differentiation of pluripotent cells |
US8518397B2 (en) * | 2009-08-14 | 2013-08-27 | Case Western Reserve University | Notch induced natural killer cell generation and therapeutic uses |
AU2010315712B2 (en) | 2009-10-19 | 2014-04-17 | FUJIFILM Cellular Dynamics, Inc. | Cardiomyocyte production |
WO2011058558A2 (en) | 2009-11-12 | 2011-05-19 | Technion Research & Development Foundation Ltd. | Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state |
BR112012020958A2 (pt) * | 2010-02-22 | 2015-09-15 | Univ Paris Curie | "meio de cultura para a criação e/ou diferenciação de células da linhagem hemapo |
CA2802087A1 (en) | 2010-06-15 | 2011-12-22 | Cellular Dynamics International, Inc. | A compendium of ready-built stem cell models for interrogation of biological response |
EP2601289B1 (en) | 2010-08-04 | 2017-07-12 | Cellular Dynamics International, Inc. | Reprogramming immortalized b cells |
CN102080065A (zh) * | 2010-12-09 | 2011-06-01 | 协和干细胞基因工程有限公司 | 一种用于脐带血造血干细胞扩增的培养体系及其应用 |
WO2012135253A1 (en) | 2011-03-29 | 2012-10-04 | Geron Corporation | Enriched populations of cardiomyocyte lineage cells from pluripotent stem cells |
CN102732483B (zh) * | 2011-03-31 | 2014-12-03 | 北京大学 | 造血祖细胞的制备方法及其专用培养基 |
GB201210857D0 (en) | 2012-06-19 | 2012-08-01 | Cambridge Entpr Ltd | Transcription factor mediated programming towards megakaryocytes |
EP2934555B1 (en) | 2012-12-21 | 2021-09-22 | Astellas Institute for Regenerative Medicine | Methods for production of platelets from pluripotent stem cells |
KR102580225B1 (ko) | 2013-06-11 | 2023-09-20 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | SC-β 세포 및 조성물 그리고 그 생성 방법 |
AU2015249371B2 (en) | 2014-04-24 | 2020-04-30 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
US10190096B2 (en) | 2014-12-18 | 2019-01-29 | President And Fellows Of Harvard College | Methods for generating stem cell-derived β cells and uses thereof |
CN107614678B (zh) | 2014-12-18 | 2021-04-30 | 哈佛学院校长同事会 | 干细胞来源的β细胞的产生方法及其使用方法 |
US10443042B2 (en) | 2014-12-18 | 2019-10-15 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof |
US10724003B2 (en) * | 2015-01-16 | 2020-07-28 | Agency For Science, Technology And Research | Method of differentiating human pluripotent stem cells into primitive macrophages |
CN104694471A (zh) * | 2015-03-25 | 2015-06-10 | 奥思达干细胞有限公司 | 体外诱导胚胎干细胞分化为红系细胞的方法 |
CN104857503A (zh) * | 2015-05-29 | 2015-08-26 | 华东理工大学 | 促进造血损伤修复的药物组合物 |
KR101756337B1 (ko) | 2015-08-12 | 2017-07-10 | 고려대학교 산학협력단 | Cxcr2 억제를 통한 인간 전분화능 줄기세포의 내배엽 및 중배엽 분화 방법 |
CN105238758A (zh) * | 2015-09-17 | 2016-01-13 | 中国科学院广州生物医药与健康研究院 | 一种体外获得造血干/祖细胞的方法 |
JP6983771B2 (ja) | 2015-10-30 | 2021-12-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California | 幹細胞からt細胞を作製する方法および該t細胞を用いた免疫療法的方法 |
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CA2307807C (en) | 1997-10-23 | 2008-09-02 | Andrea G. Bodnar | Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture |
CA2219869A1 (en) | 1997-10-31 | 1999-04-30 | Hsc Research And Development Limited Partnership | Human cd-34 hematopoietic stem cells |
WO2000012682A1 (en) * | 1998-09-01 | 2000-03-09 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells with compatible histocompatibility genes |
US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
AU7445800A (en) | 1999-09-27 | 2001-04-30 | Chugai Seiyaku Kabushiki Kaisha | Method of prolonging normal cell life span |
US6280718B1 (en) | 1999-11-08 | 2001-08-28 | Wisconsin Alumni Reasearch Foundation | Hematopoietic differentiation of human pluripotent embryonic stem cells |
CA2397292A1 (en) | 2000-01-14 | 2001-07-19 | Bresagen Limited | Cell production |
US6458589B1 (en) | 2000-04-27 | 2002-10-01 | Geron Corporation | Hepatocyte lineage cells derived from pluripotent stem cells |
US20020009743A1 (en) | 2000-05-17 | 2002-01-24 | Carpenter Melissa K. | Neural progenitor cell populations |
EP1335972A2 (en) | 2000-11-22 | 2003-08-20 | Geron Corporation | Tolerizing allografts of pluripotent stem cells |
US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
DE10061334A1 (de) * | 2000-12-04 | 2002-06-13 | Max Delbrueck Centrum | Verwendung von aus embryonalen Stammzellen hergeleiteten Zellen zur Erhöhung der Transplantationstoleranz und zur Wiederherstellung zerstörten Gewebes |
BR0211066A (pt) * | 2001-07-10 | 2006-08-29 | Johnson & Johnson Res Pty Ltd | produção de células progenitoras hematopoiéticas transduzidas |
-
2002
- 2002-12-06 AU AU2002366603A patent/AU2002366603B2/en not_active Ceased
- 2002-12-06 GB GB0503865A patent/GB2412379B/en not_active Expired - Fee Related
- 2002-12-06 KR KR1020137015273A patent/KR20130072272A/ko not_active Application Discontinuation
- 2002-12-06 US US10/313,196 patent/US20030153082A1/en not_active Abandoned
- 2002-12-06 KR KR1020107024253A patent/KR101457742B1/ko not_active IP Right Cessation
- 2002-12-06 WO PCT/US2002/039091 patent/WO2003050251A2/en active Application Filing
- 2002-12-06 EP EP02804740.5A patent/EP1463803B1/en not_active Expired - Lifetime
- 2002-12-06 KR KR10-2004-7008756A patent/KR20040081741A/ko not_active Application Discontinuation
- 2002-12-06 CN CN200910174800.4A patent/CN102008503B/zh not_active Expired - Fee Related
- 2002-12-06 JP JP2003551273A patent/JP5364224B2/ja not_active Expired - Fee Related
- 2002-12-06 CN CNA028270649A patent/CN1630716A/zh active Pending
- 2002-12-06 IL IL16213002A patent/IL162130A0/xx unknown
- 2002-12-06 CA CA2469483A patent/CA2469483C/en not_active Expired - Fee Related
- 2002-12-06 EP EP10175120A patent/EP2292734A1/en not_active Withdrawn
- 2002-12-06 GB GB0414957A patent/GB2399572B/en not_active Expired - Fee Related
-
2004
- 2004-05-23 IL IL162130A patent/IL162130A/en not_active IP Right Cessation
-
2008
- 2008-11-10 AU AU2008243182A patent/AU2008243182A1/en not_active Abandoned
-
2009
- 2009-09-06 IL IL200768A patent/IL200768A/en active IP Right Grant
- 2009-11-24 JP JP2009265829A patent/JP2010075195A/ja active Pending
-
2013
- 2013-06-18 JP JP2013127621A patent/JP2013236636A/ja not_active Withdrawn
-
2016
- 2016-07-26 JP JP2016146156A patent/JP2016187354A/ja active Pending
Also Published As
Publication number | Publication date |
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GB0414957D0 (en) | 2004-08-04 |
GB2412379A (en) | 2005-09-28 |
EP1463803A2 (en) | 2004-10-06 |
CA2469483C (en) | 2017-07-25 |
KR101457742B1 (ko) | 2014-11-03 |
CN102008503B (zh) | 2018-10-09 |
GB0503865D0 (en) | 2005-04-06 |
JP2010075195A (ja) | 2010-04-08 |
JP2005511084A (ja) | 2005-04-28 |
US20030153082A1 (en) | 2003-08-14 |
CA2469483A1 (en) | 2003-06-19 |
GB2399572B (en) | 2006-06-07 |
AU2008243182A1 (en) | 2008-12-04 |
WO2003050251A2 (en) | 2003-06-19 |
IL200768A0 (en) | 2010-05-17 |
KR20040081741A (ko) | 2004-09-22 |
AU2002366603B2 (en) | 2008-10-02 |
CN102008503A (zh) | 2011-04-13 |
EP2292734A1 (en) | 2011-03-09 |
IL200768A (en) | 2011-10-31 |
JP2016187354A (ja) | 2016-11-04 |
GB2399572A (en) | 2004-09-22 |
JP5364224B2 (ja) | 2013-12-11 |
GB2412379B (en) | 2006-03-29 |
EP1463803B1 (en) | 2018-02-14 |
JP2013236636A (ja) | 2013-11-28 |
WO2003050251A3 (en) | 2003-12-24 |
KR20100120723A (ko) | 2010-11-16 |
AU2002366603A1 (en) | 2003-06-23 |
CN1630716A (zh) | 2005-06-22 |
EP1463803A4 (en) | 2005-02-02 |
KR20130072272A (ko) | 2013-07-01 |
IL162130A (en) | 2010-05-31 |
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