IL161468A0 - Method of producing human beta cell lines - Google Patents

Method of producing human beta cell lines

Info

Publication number
IL161468A0
IL161468A0 IL16146802A IL16146802A IL161468A0 IL 161468 A0 IL161468 A0 IL 161468A0 IL 16146802 A IL16146802 A IL 16146802A IL 16146802 A IL16146802 A IL 16146802A IL 161468 A0 IL161468 A0 IL 161468A0
Authority
IL
Israel
Prior art keywords
human beta
pancreatic
beta cell
cell lines
producing human
Prior art date
Application number
IL16146802A
Other languages
English (en)
Original Assignee
Univ Paris 7 Denis Diderot Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Paris 7 Denis Diderot Ct filed Critical Univ Paris 7 Denis Diderot Ct
Publication of IL161468A0 publication Critical patent/IL161468A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL16146802A 2001-10-19 2002-10-18 Method of producing human beta cell lines IL161468A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/981,750 US20030077256A1 (en) 2001-10-19 2001-10-19 Pancreas regeneration using embryonic pancreatic cells
PCT/IB2002/004599 WO2003033685A2 (en) 2001-10-19 2002-10-18 Method of producing human beta cell lines

Publications (1)

Publication Number Publication Date
IL161468A0 true IL161468A0 (en) 2004-09-27

Family

ID=25528625

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16146802A IL161468A0 (en) 2001-10-19 2002-10-18 Method of producing human beta cell lines

Country Status (18)

Country Link
US (2) US20030077256A1 (ko)
EP (1) EP1456356B1 (ko)
JP (1) JP2005505635A (ko)
KR (1) KR20040080430A (ko)
CN (1) CN1662644A (ko)
AT (1) ATE452967T1 (ko)
BR (1) BR0213429A (ko)
CA (1) CA2463979A1 (ko)
DE (1) DE60234862D1 (ko)
GB (1) GB2397825B (ko)
HR (1) HRP20040446A2 (ko)
HU (1) HUP0600102A2 (ko)
IL (1) IL161468A0 (ko)
NZ (1) NZ532965A (ko)
PL (1) PL370167A1 (ko)
RU (1) RU2004115108A (ko)
WO (1) WO2003033685A2 (ko)
ZA (1) ZA200403646B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1924690A4 (en) * 2005-09-15 2009-07-29 Burnham Inst Medical Research METHODS FOR SCREENING COMPOUNDS MODULATING THE ACTIVITY OF THE INSULIN PROMOTER
EP2121905B1 (en) * 2007-02-21 2016-02-10 Sarl Endocells Human pancreatic beta cell lines for diagnostic of diabetes
US8859286B2 (en) * 2013-03-14 2014-10-14 Viacyte, Inc. In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells
KR102205234B1 (ko) 2013-06-11 2021-01-20 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 SC-β 세포 및 조성물 그리고 그 생성 방법
US10443042B2 (en) 2014-12-18 2019-10-15 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
DK3234110T3 (da) 2014-12-18 2024-05-13 Harvard College FREMGANGSMÅDER TIL GENERERING AF STAMCELLE-AFLEDTE ß-CELLER OG ANVENDELSER DERAF
CN107614678B (zh) 2014-12-18 2021-04-30 哈佛学院校长同事会 干细胞来源的β细胞的产生方法及其使用方法
IL274436B2 (en) 2017-11-15 2024-01-01 Semma Therapeutics Inc Preparations for the production of islet cells and methods of use
EP3833365A4 (en) 2018-08-10 2022-05-11 Vertex Pharmaceuticals Incorporated ISLE DIFFERENTIATION DERIVED FROM STEM CELLS
CN110029130A (zh) * 2019-04-24 2019-07-19 皖南医学院第一附属医院（皖南医学院弋矶山医院） 基于CRISPR/Cas9***在Beta-TC-6细胞株中剔除Sidt2基因方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5723333A (en) * 1995-02-10 1998-03-03 Regents Of The University Of California Human pancreatic cell lines: developments and uses

Also Published As

Publication number Publication date
DE60234862D1 (de) 2010-02-04
BR0213429A (pt) 2004-11-09
WO2003033685A2 (en) 2003-04-24
RU2004115108A (ru) 2005-02-10
EP1456356B1 (en) 2009-12-23
HUP0600102A2 (en) 2006-05-29
WO2003033685A3 (en) 2004-05-27
KR20040080430A (ko) 2004-09-18
ATE452967T1 (de) 2010-01-15
ZA200403646B (en) 2005-01-26
HRP20040446A2 (en) 2005-04-30
NZ532965A (en) 2006-04-28
PL370167A1 (en) 2005-05-16
EP1456356A2 (en) 2004-09-15
GB2397825B (en) 2006-02-22
GB0411052D0 (en) 2004-06-23
US20030219418A1 (en) 2003-11-27
JP2005505635A (ja) 2005-02-24
GB2397825A (en) 2004-08-04
CN1662644A (zh) 2005-08-31
CA2463979A1 (en) 2003-04-24
US20030077256A1 (en) 2003-04-24

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