IL155986A0 - 4- (biphenylcarbonylamino) piperidine derivatives as mtp inhibitors - Google Patents

4- (biphenylcarbonylamino) piperidine derivatives as mtp inhibitors

Info

Publication number
IL155986A0
IL155986A0 IL15598601A IL15598601A IL155986A0 IL 155986 A0 IL155986 A0 IL 155986A0 IL 15598601 A IL15598601 A IL 15598601A IL 15598601 A IL15598601 A IL 15598601A IL 155986 A0 IL155986 A0 IL 155986A0
Authority
IL
Israel
Prior art keywords
biphenylcarbonylamino
piperidine derivatives
mtp inhibitors
mtp
inhibitors
Prior art date
Application number
IL15598601A
Other languages
English (en)
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL155986A0 publication Critical patent/IL155986A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL15598601A 2000-11-23 2001-10-25 4- (biphenylcarbonylamino) piperidine derivatives as mtp inhibitors IL155986A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015143A FR2816940A1 (fr) 2000-11-23 2000-11-23 Derives de 4-(biphenylcarbonylamino)-piperidine, compositions les contenant et leur utilisation
PCT/EP2001/012326 WO2002042291A1 (en) 2000-11-23 2001-10-25 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors

Publications (1)

Publication Number Publication Date
IL155986A0 true IL155986A0 (en) 2003-12-23

Family

ID=8856805

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15598601A IL155986A0 (en) 2000-11-23 2001-10-25 4- (biphenylcarbonylamino) piperidine derivatives as mtp inhibitors

Country Status (20)

Country Link
US (1) US20040034028A1 (xx)
EP (1) EP1335912A1 (xx)
JP (1) JP2004514676A (xx)
KR (1) KR20030060954A (xx)
CN (1) CN1476445A (xx)
AR (1) AR031499A1 (xx)
AU (1) AU2002221745A1 (xx)
BR (1) BR0115520A (xx)
CA (1) CA2429326A1 (xx)
CZ (1) CZ20031619A3 (xx)
FR (1) FR2816940A1 (xx)
HU (1) HUP0400819A2 (xx)
IL (1) IL155986A0 (xx)
MX (1) MXPA03004540A (xx)
NO (1) NO20032315L (xx)
PE (1) PE20020595A1 (xx)
PL (1) PL365939A1 (xx)
RU (1) RU2003117458A (xx)
SK (1) SK7362003A3 (xx)
WO (1) WO2002042291A1 (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TNSN03146A1 (fr) 2001-06-28 2005-12-23 Pfizer Prod Inc Indoles, benzofurannes et benzothiophenes a substituant triamide, utiles comme inhibiteurs de secretion de la proteine de transfert des triglycerides microsomaux et/ou de l'apolipo-proteine b (apo b).
CN1943786A (zh) 2002-02-28 2007-04-11 日本烟草产业株式会社 酯化合物及其医药用途
FR2856685B1 (fr) * 2003-06-25 2005-09-23 Merck Sante Sas Derives de thiazolylpiperidine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
EP1669345A4 (en) 2003-08-29 2008-02-20 Japan Tobacco Inc ESTER DERIVATIVE AND MEDICAL USE THEREOF
FR2865733B1 (fr) * 2004-02-04 2007-10-12 Merck Sante Sas Derives de thiazolylimidazole, leurs procedes de preparation, les compositions pharmaceutiques qui les contiennent et leurs applications en medecine
FR2871463B1 (fr) * 2004-06-11 2006-09-22 Merck Sante Soc Par Actions Si Derives a structure aroyl-o-piperidine, leurs procedes de preparation, les compositions pharmaceutiques qui les contiennent et leurs applications en therapeutique
US8101774B2 (en) 2004-10-18 2012-01-24 Japan Tobacco Inc. Ester derivatives and medicinal use thereof
FR2884831B1 (fr) * 2005-04-22 2007-08-10 Merck Sante Soc Par Actions Si Methode de criblage de composes inhibiteurs de la mtp
JO2653B1 (en) 2006-10-24 2012-06-17 شركة جانسين فارماسوتيكا ان. في Tetrahydroflavin 1-carboxylic acid substituted with pyridine or pyrazine inhibit MTB
JP5525261B2 (ja) 2006-10-24 2014-06-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｍｔｐ阻害性テトラヒドロ−ナフタレン−１−カルボン酸誘導体
ES2387471T3 (es) * 2006-12-20 2012-09-24 Amgen Inc. Compuestos heterocíclicos y su uso en el tratamiento de la inflamación, la angiogénesis y el cáncer
AR074466A1 (es) 2008-12-05 2011-01-19 Sanofi Aventis Piperidina espiro pirrolidinona y piperidinona sustituidas y su uso terapeutico en enfermedades mediadas por la modulacion de los receptores h3.
BR112012004533B1 (pt) 2009-09-03 2021-11-09 Bioenergenix Composto, composição farmacêutica, e uso do composto
US9073902B2 (en) 2011-01-05 2015-07-07 Bioenergenix, Llc Substituted quinoxaline carboxylic acid compounds for the inhibition of PASK
JP6139415B2 (ja) 2011-03-02 2017-05-31 バイオエナジェニックス Ｐａｓｋの阻害のための複素環化合物
US8916561B2 (en) 2011-03-02 2014-12-23 Bioenergenix, Llc Substituted quinoxaline compounds for the inhibition of PASK
JP6664632B2 (ja) * 2013-09-30 2020-03-13 国立大学法人 東京大学 アディポネクチン受容体活性化化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8528234D0 (en) * 1985-11-15 1985-12-18 Wyeth John & Brother Ltd Heterocyclic compounds
US5595872A (en) * 1992-03-06 1997-01-21 Bristol-Myers Squibb Company Nucleic acids encoding microsomal trigyceride transfer protein
CA2123728A1 (en) * 1993-05-21 1994-11-22 Noriyoshi Sueda Urea derivatives and their use as acat inhibitors
EP0863141B1 (en) * 1995-10-13 2001-09-12 Banyu Pharmaceutical Co., Ltd. Substituted heteroaromatic derivatives
AU2793197A (en) * 1996-05-31 1998-01-05 Banyu Pharmaceutical Co., Ltd. 1,4-disubstituted piperidine derivatives

Also Published As

Publication number Publication date
CA2429326A1 (en) 2002-05-30
FR2816940A1 (fr) 2002-05-24
NO20032315D0 (no) 2003-05-22
SK7362003A3 (en) 2003-11-04
AR031499A1 (es) 2003-09-24
RU2003117458A (ru) 2004-12-27
PE20020595A1 (es) 2002-07-08
CZ20031619A3 (cs) 2003-09-17
NO20032315L (no) 2003-05-22
AU2002221745A1 (en) 2002-06-03
EP1335912A1 (en) 2003-08-20
HUP0400819A2 (hu) 2004-07-28
CN1476445A (zh) 2004-02-18
JP2004514676A (ja) 2004-05-20
US20040034028A1 (en) 2004-02-19
MXPA03004540A (es) 2003-09-10
WO2002042291A1 (en) 2002-05-30
KR20030060954A (ko) 2003-07-16
PL365939A1 (en) 2005-01-24
BR0115520A (pt) 2003-09-16

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