IL151309A0 - Purification of lh and pharmaceutical compositions containing it - Google Patents

Purification of lh and pharmaceutical compositions containing it

Info

Publication number
IL151309A0
IL151309A0 IL15130901A IL15130901A IL151309A0 IL 151309 A0 IL151309 A0 IL 151309A0 IL 15130901 A IL15130901 A IL 15130901A IL 15130901 A IL15130901 A IL 15130901A IL 151309 A0 IL151309 A0 IL 151309A0
Authority
IL
Israel
Prior art keywords
purification
ion
pharmaceutical compositions
compositions containing
reverse phase
Prior art date
Application number
IL15130901A
Other languages
English (en)
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of IL151309A0 publication Critical patent/IL151309A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Semiconductor Lasers (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15130901A 2000-02-22 2001-01-22 Purification of lh and pharmaceutical compositions containing it IL151309A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00103692 2000-02-22
PCT/EP2001/000666 WO2001062774A2 (en) 2000-02-22 2001-01-22 Purified lh

Publications (1)

Publication Number Publication Date
IL151309A0 true IL151309A0 (en) 2003-04-10

Family

ID=8167926

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15130901A IL151309A0 (en) 2000-02-22 2001-01-22 Purification of lh and pharmaceutical compositions containing it
IL151309A IL151309A (en) 2000-02-22 2002-08-18 Cleansing of HL and pharmaceutical preparations containing it

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL151309A IL151309A (en) 2000-02-22 2002-08-18 Cleansing of HL and pharmaceutical preparations containing it

Country Status (31)

Country Link
US (2) US7053054B2 (pl)
EP (2) EP1261622B1 (pl)
JP (1) JP4959898B2 (pl)
KR (1) KR100808149B1 (pl)
CN (1) CN100480258C (pl)
AT (1) ATE356138T1 (pl)
AU (1) AU780377B2 (pl)
BG (1) BG65761B1 (pl)
BR (2) BR122012018280B8 (pl)
CA (1) CA2399100C (pl)
CY (1) CY1108056T1 (pl)
CZ (1) CZ303274B6 (pl)
DE (1) DE60127100T2 (pl)
DK (1) DK1261622T3 (pl)
EA (1) EA004385B1 (pl)
EE (1) EE04932B1 (pl)
ES (1) ES2278722T3 (pl)
HK (1) HK1052014A1 (pl)
HR (1) HRP20020651B1 (pl)
HU (1) HU227007B1 (pl)
IL (2) IL151309A0 (pl)
MX (1) MXPA02007867A (pl)
NO (1) NO328693B1 (pl)
PL (1) PL207728B1 (pl)
PT (1) PT1261622E (pl)
RS (1) RS50416B (pl)
SI (1) SI1261622T1 (pl)
SK (1) SK287041B6 (pl)
UA (2) UA92145C2 (pl)
WO (1) WO2001062774A2 (pl)
ZA (1) ZA200206108B (pl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL207728B1 (pl) * 2000-02-22 2011-01-31 Serono Lab Sposób oczyszczania LH z próbki, zastosowanie rekombinowanego hLH oraz kompozycja farmaceutyczna
DE10235168A1 (de) * 2002-08-01 2004-02-12 Aventis Pharma Deutschland Gmbh Verfahren zur Reinigung von Preproinsulin
BRPI0409571B1 (pt) * 2003-03-04 2016-05-31 Aspenbio Pharma Inc método para manter uma ou mais gravidezes em um ou mais mamíferos
CN1283792C (zh) * 2003-11-14 2006-11-08 余伟明 生物大分子组分相分离法
JP4763616B2 (ja) * 2003-12-22 2011-08-31 アレス トレーディング ソシエテ アノニム Ｆｓｈを精製するための方法
EP1709065B1 (en) * 2004-10-04 2010-06-02 Novetide Ltd. A counterion exchange process for peptides
PL1809663T3 (pl) * 2004-11-09 2009-01-30 Ares Trading Sa Sposób oczyszczania FSH
LT1917276T (lt) * 2005-08-26 2018-05-25 Ares Trading S.A. Glikozilinto interferono beta gavimo būdas
AU2006323925B2 (en) 2005-12-09 2012-08-02 Ares Trading S.A. Method for purifying FSH or a FSH mutant
JP2011500757A (ja) * 2007-10-22 2011-01-06 メルク セローノ ソシエテ アノニム Ｆｃ含有タンパク質の精製方法
US20100249381A1 (en) * 2007-10-22 2010-09-30 David Delvaille Method for Purifying FC-Fusion Proteins
CN101928342B (zh) * 2009-06-18 2013-05-08 上海天伟生物制药有限公司 一种高纯度绝经期促性腺素及其制备方法和用途
CN106999546A (zh) * 2014-05-01 2017-08-01 弗吉尼亚技术知识资产公司 角蛋白纳米材料及其制备方法
CN104569441B (zh) * 2015-01-19 2016-02-03 成都大熊猫繁育研究基地 大熊猫尿液促黄体素的酶联检测方法及其应用
WO2020229699A1 (en) 2019-05-16 2020-11-19 Ceva Sante Animale Compositions and methods for increasing reproduction performance in non human mammals using recombinant luteinizing hormone

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002757A1 (en) * 1988-09-02 1990-03-22 Integrated Genetics, Inc. Heteropolymeric protein
DE69029799T2 (de) * 1989-02-21 1997-05-28 Washington University, St. Louis, Mo. Modifizierte formen von fortpflanzungshormonen
US5087615A (en) * 1989-03-17 1992-02-11 Applied Research Systems Ars Holding N.V. Novel method of ovulation induction in humans
IT1250075B (it) * 1991-12-18 1995-03-30 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti gonadotropine.
IT1287138B1 (it) * 1996-11-07 1998-08-04 Ibsa Inst Biochimique Sa Procedimento per la separazione e purificazione di fsh e lh
TW518235B (en) * 1997-01-15 2003-01-21 Akzo Nobel Nv A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage
PT1775346E (pt) * 1997-06-25 2009-08-25 Merck Serono Sa Análogos de hormonas glicoproteicas reticulados com ligações dissulfureto, sua preparação e utilização
PL207728B1 (pl) * 2000-02-22 2011-01-31 Serono Lab Sposób oczyszczania LH z próbki, zastosowanie rekombinowanego hLH oraz kompozycja farmaceutyczna

Also Published As

Publication number Publication date
AU3543601A (en) 2001-09-03
US7053054B2 (en) 2006-05-30
JP4959898B2 (ja) 2012-06-27
KR100808149B1 (ko) 2008-02-29
US20030186893A1 (en) 2003-10-02
UA92145C2 (en) 2010-10-11
YU60302A (sh) 2005-09-19
CZ20022856A3 (cs) 2003-01-15
BRPI0108553B1 (pt) 2016-06-14
NO20023963L (no) 2002-08-20
EP1777231A2 (en) 2007-04-25
NO328693B1 (no) 2010-04-26
BG65761B1 (bg) 2009-10-30
EP1261622A2 (en) 2002-12-04
CY1108056T1 (el) 2013-09-04
US20060079460A1 (en) 2006-04-13
PL207728B1 (pl) 2011-01-31
DE60127100T2 (de) 2007-06-28
DK1261622T3 (da) 2007-05-29
EP1261622B1 (en) 2007-03-07
BRPI0108553B8 (pt) 2021-05-25
HUP0301814A3 (en) 2004-10-28
CN100480258C (zh) 2009-04-22
EE04932B1 (et) 2007-12-17
IL151309A (en) 2010-11-30
AU780377B2 (en) 2005-03-17
BG107001A (bg) 2003-04-30
BR122012018280B1 (pt) 2018-01-09
ATE356138T1 (de) 2007-03-15
CZ303274B6 (cs) 2012-07-11
BR122012018280B8 (pt) 2021-05-25
EA004385B1 (ru) 2004-04-29
BR0108553A (pt) 2003-12-23
CA2399100C (en) 2011-11-08
ZA200206108B (en) 2003-07-31
PT1261622E (pt) 2007-04-30
EP1777231A3 (en) 2007-11-07
CN1404486A (zh) 2003-03-19
HU227007B1 (en) 2010-04-28
SK12052002A3 (sk) 2002-12-03
DE60127100D1 (de) 2007-04-19
MXPA02007867A (es) 2003-02-10
WO2001062774A2 (en) 2001-08-30
WO2001062774A3 (en) 2002-03-14
HRP20020651B1 (en) 2011-01-31
NO20023963D0 (no) 2002-08-20
EE200200464A (et) 2003-12-15
JP2003532636A (ja) 2003-11-05
HRP20020651A2 (en) 2004-12-31
SI1261622T1 (sl) 2007-06-30
HK1052014A1 (en) 2003-08-29
SK287041B6 (sk) 2009-10-07
EA200200893A1 (ru) 2003-02-27
ES2278722T3 (es) 2007-08-16
PL362891A1 (pl) 2004-11-02
CA2399100A1 (en) 2001-08-30
RS50416B (sr) 2009-12-31
HUP0301814A2 (hu) 2003-08-28
KR20030001358A (ko) 2003-01-06
UA78676C2 (en) 2007-04-25

Similar Documents

Publication Publication Date Title
IL151309A0 (en) Purification of lh and pharmaceutical compositions containing it
IL151308A0 (en) PURIFICATION OF hCG AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT
WO1997049373A3 (en) Treatment and prevention of hiv infection by administration of derivatives of human chorionic gonadotropin
KR910700260A (ko) 호중구-활성화 펩티드-2
CY1107666T1 (el) Διαδικασια για την παρασκευη συνθεσεων γοναδοτροπινης
CA2176494A1 (en) Purification of Hemoglobin
RU2005118752A (ru) Позиционные изомеры пэгилированного интерферона l-2а (конъюгата пэг-ifn-l-2а)
Hooper et al. Histone III: II. ISOLATION AND SEQUENCES OF CHYMOTRYPTIC PEPTIDES FROM CALF THYMUS HISTONE III
IT1265304B1 (it) Derivati metallorganici degli acidi s-acil-2-(s)-(2-pirrolidon-5-(s)- carbonilamido)-3-mercapto propionici con magnesio, procedimento per la