IL150643A0 - Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 [4r-(3s-hydroxy-1-methyl) piperidinyl]-4h-1-benzopyran-4-one - Google Patents

Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 [4r-(3s-hydroxy-1-methyl) piperidinyl]-4h-1-benzopyran-4-one

Info

Publication number: IL150643A0
Authority: IL; Israel
Prior art keywords: benzopyran; piperidinyl; chlorophenyl; dihydroxy; cis
Prior art date: 2000-01-18

Application number

IL15064301A

Other languages

English (en)

Original Assignee

Aventis Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-18

Filing date

2001-01-08

Publication date

2003-02-12

2001-01-08 Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc

2003-02-12 Publication of IL150643A0 publication Critical patent/IL150643A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Immunology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

IL15064301A 2000-01-18 2001-01-08 Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 [4r-(3s-hydroxy-1-methyl) piperidinyl]-4h-1-benzopyran-4-one IL150643A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US48781500A	2000-01-18	2000-01-18
PCT/US2001/000520 WO2001053294A1 (en)	2000-01-18	2001-01-08	Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one

Publications (1)

Publication Number	Publication Date
IL150643A0 true IL150643A0 (en)	2003-02-12

Family

ID=23937213

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15064301A IL150643A0 (en)	2000-01-18	2001-01-08	Ethanol solvate of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 [4r-(3s-hydroxy-1-methyl) piperidinyl]-4h-1-benzopyran-4-one
IL150643A IL150643A (en)	2000-01-18	2002-07-08	Ethanol solvate of (- (- cis – 2 -) - chlorophenyl (–5,7– dehydroxy – R4–) S] –38– hydroxy – 1 – methylpipridinyl [- H4– 1 – benzopyran – 4 – on (II FORM) , Its preparation and medicinal preparations containing it

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL150643A IL150643A (en)	2000-01-18	2002-07-08	Ethanol solvate of (- (- cis – 2 -) - chlorophenyl (–5,7– dehydroxy – R4–) S] –38– hydroxy – 1 – methylpipridinyl [- H4– 1 – benzopyran – 4 – on (II FORM) , Its preparation and medicinal preparations containing it

Country Status (26)

Country	Link
EP (1)	EP1252155B1 (xx)
JP (1)	JP2003520798A (xx)
KR (1)	KR100825530B1 (xx)
CN (1)	CN1395577A (xx)
AR (1)	AR027226A1 (xx)
AT (1)	ATE284400T1 (xx)
AU (1)	AU2001230869A1 (xx)
BR (1)	BR0107724A (xx)
CA (1)	CA2397594C (xx)
CZ (1)	CZ301235B6 (xx)
DE (1)	DE60107652T2 (xx)
DK (1)	DK1252155T3 (xx)
EA (1)	EA005182B1 (xx)
ES (1)	ES2228800T3 (xx)
HU (1)	HU225155B1 (xx)
IL (2)	IL150643A0 (xx)
MX (1)	MXPA02006965A (xx)
NO (1)	NO322626B1 (xx)
NZ (1)	NZ520281A (xx)
PL (1)	PL201690B1 (xx)
PT (1)	PT1252155E (xx)
SI (1)	SI1252155T1 (xx)
SK (1)	SK287216B6 (xx)
TW (1)	TWI293072B (xx)
WO (1)	WO2001053294A1 (xx)
ZA (1)	ZA200205640B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA3034875C (en)	2016-08-23	2024-05-28	Eisai R&D Management Co., Ltd.	Combination therapies for the treatment of hepatocellular carcinoma
EP4218820A3 (en)	2017-03-16	2023-09-20	Eisai R&D Management Co., Ltd.	Combination therapies for the treatment of breast cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN164232B (xx) *	1986-04-11	1989-02-04	Hoechst India
DE3836676A1 (de) *	1988-10-28	1990-05-03	Hoechst Ag	Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
US5284856A (en) *	1988-10-28	1994-02-08	Hoechst Aktiengesellschaft	Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
US5908934A (en) *	1996-09-26	1999-06-01	Bristol-Myers Squibb Company	Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

2001
- 2001-01-08 IL IL15064301A patent/IL150643A0/xx unknown
- 2001-01-08 ES ES01902993T patent/ES2228800T3/es not_active Expired - Lifetime
- 2001-01-08 PL PL355992A patent/PL201690B1/pl not_active IP Right Cessation
- 2001-01-08 WO PCT/US2001/000520 patent/WO2001053294A1/en active IP Right Grant
- 2001-01-08 EP EP01902993A patent/EP1252155B1/en not_active Expired - Lifetime
- 2001-01-08 JP JP2001553768A patent/JP2003520798A/ja active Pending
- 2001-01-08 PT PT01902993T patent/PT1252155E/pt unknown
- 2001-01-08 SK SK1037-2002A patent/SK287216B6/sk not_active IP Right Cessation
- 2001-01-08 BR BR0107724-4A patent/BR0107724A/pt not_active Application Discontinuation
- 2001-01-08 AU AU2001230869A patent/AU2001230869A1/en not_active Abandoned
- 2001-01-08 CA CA2397594A patent/CA2397594C/en not_active Expired - Fee Related
- 2001-01-08 SI SI200130293T patent/SI1252155T1/xx unknown
- 2001-01-08 NZ NZ520281A patent/NZ520281A/en not_active IP Right Cessation
- 2001-01-08 AT AT01902993T patent/ATE284400T1/de active
- 2001-01-08 CN CN01803857A patent/CN1395577A/zh active Pending
- 2001-01-08 DK DK01902993T patent/DK1252155T3/da active
- 2001-01-08 KR KR1020027009140A patent/KR100825530B1/ko not_active IP Right Cessation
- 2001-01-08 EA EA200200776A patent/EA005182B1/ru not_active IP Right Cessation
- 2001-01-08 CZ CZ20022467A patent/CZ301235B6/cs not_active IP Right Cessation
- 2001-01-08 DE DE60107652T patent/DE60107652T2/de not_active Expired - Lifetime
- 2001-01-08 MX MXPA02006965A patent/MXPA02006965A/es active IP Right Grant
- 2001-01-08 HU HU0204297A patent/HU225155B1/hu not_active IP Right Cessation
- 2001-01-17 TW TW090101052A patent/TWI293072B/zh not_active IP Right Cessation
- 2001-01-17 AR ARP010100186A patent/AR027226A1/es not_active Application Discontinuation
2002
- 2002-07-08 IL IL150643A patent/IL150643A/en not_active IP Right Cessation
- 2002-07-12 NO NO20023385A patent/NO322626B1/no not_active IP Right Cessation
- 2002-07-15 ZA ZA200205640A patent/ZA200205640B/en unknown

Also Published As

Publication number	Publication date
ZA200205640B (en)	2003-11-26
ATE284400T1 (de)	2004-12-15
TWI293072B (en)	2008-02-01
AR027226A1 (es)	2003-03-19
HU225155B1 (en)	2006-07-28
KR100825530B1 (ko)	2008-04-25
SK287216B6 (sk)	2010-03-08
CZ301235B6 (cs)	2009-12-16
ES2228800T3 (es)	2005-04-16
NO20023385D0 (no)	2002-07-12
DE60107652D1 (de)	2005-01-13
IL150643A (en)	2009-08-03
CZ20022467A3 (cs)	2002-10-16
EA005182B1 (ru)	2004-12-30
BR0107724A (pt)	2002-10-01
PL355992A1 (en)	2004-05-31
DE60107652T2 (de)	2005-12-22
CN1395577A (zh)	2003-02-05
CA2397594C (en)	2010-03-23
NO20023385L (no)	2002-08-27
MXPA02006965A (es)	2004-09-06
NZ520281A (en)	2004-04-30
DK1252155T3 (da)	2005-04-04
EP1252155A1 (en)	2002-10-30
JP2003520798A (ja)	2003-07-08
SK10372002A3 (sk)	2002-12-03
KR20020069514A (ko)	2002-09-04
HUP0204297A3 (en)	2005-04-28
WO2001053294A1 (en)	2001-07-26
CA2397594A1 (en)	2001-07-26
NO322626B1 (no)	2006-11-06
EP1252155B1 (en)	2004-12-08
HUP0204297A2 (hu)	2003-04-28
EA200200776A1 (ru)	2002-12-26
PL201690B1 (pl)	2009-04-30
AU2001230869A1 (en)	2001-07-31
SI1252155T1 (en)	2005-06-30
PT1252155E (pt)	2005-04-29

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