IL146434A0 - Pharmaceutical compositions containing ecteinascidin 743 - Google Patents

Pharmaceutical compositions containing ecteinascidin 743

Info

Publication number: IL146434A0
Authority: IL; Israel
Prior art keywords: ecteinascidin; pharmaceutical compositions; compositions containing; pharmaceutical; containing ecteinascidin
Prior art date: 1999-05-13

Application number

IL14643400A

Other languages

English (en)

Original Assignee

Pharma Mar Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-13

Filing date

2000-05-15

Publication date

2002-07-25

1999-05-13 Priority claimed from GBGB9911183.3A external-priority patent/GB9911183D0/en

1999-05-14 Priority claimed from GBGB9911346.6A external-priority patent/GB9911346D0/en

1999-08-05 Priority claimed from GBGB9918534.0A external-priority patent/GB9918534D0/en

1999-11-15 Priority claimed from GBGB9927005.0A external-priority patent/GB9927005D0/en

1999-11-16 Priority claimed from GBGB9927106.6A external-priority patent/GB9927106D0/en

2000-03-29 Priority claimed from GB0007637A external-priority patent/GB0007637D0/en

2000-05-15 Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa

2002-07-25 Publication of IL146434A0 publication Critical patent/IL146434A0/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL14643400A 1999-05-13 2000-05-15 Pharmaceutical compositions containing ecteinascidin 743 IL146434A0 (en)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
GBGB9911183.3A GB9911183D0 (en)	1999-05-13	1999-05-13	Treatment of cancers
GBGB9911346.6A GB9911346D0 (en)	1999-05-14	1999-05-14	Treatment of cancers
GBGB9918534.0A GB9918534D0 (en)	1999-08-05	1999-08-05	Treatment of cancers
GBGB9927005.0A GB9927005D0 (en)	1999-11-15	1999-11-15	Treatment of cancers
GBGB9927106.6A GB9927106D0 (en)	1999-11-16	1999-11-16	Cancer treatment
GB0007637A GB0007637D0 (en)	2000-03-29	2000-03-29	Antitumour compound
PCT/GB2000/001857 WO2000069441A1 (en)	1999-05-13	2000-05-15	Compositions and uses of et743 for treating cancer

Publications (1)

Publication Number	Publication Date
IL146434A0 true IL146434A0 (en)	2002-07-25

Family

ID=27546594

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL14643400A IL146434A0 (en)	1999-05-13	2000-05-15	Pharmaceutical compositions containing ecteinascidin 743
IL146434A IL146434A (en)	1999-05-13	2001-11-11	Pharmaceutical preparations containing actinacidin 347

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL146434A IL146434A (en)	1999-05-13	2001-11-11	Pharmaceutical preparations containing actinacidin 347

Country Status (32)

Country	Link
US (1)	US8119638B2 (xx)
EP (3)	EP1716853B9 (xx)
JP (2)	JP2002544231A (xx)
KR (1)	KR20020019914A (xx)
CN (2)	CN1360503A (xx)
AR (1)	AR028476A1 (xx)
AT (3)	ATE375795T1 (xx)
AU (2)	AU777417B2 (xx)
BG (1)	BG65680B1 (xx)
BR (1)	BR0010531A (xx)
CA (1)	CA2373794C (xx)
CY (4)	CY1105818T1 (xx)
CZ (1)	CZ301482B6 (xx)
DE (4)	DE60030554T8 (xx)
DK (3)	DK1176964T3 (xx)
ES (2)	ES2294756T3 (xx)
FR (1)	FR08C0013I2 (xx)
HU (2)	HU229866B1 (xx)
IL (2)	IL146434A0 (xx)
LU (1)	LU91418I2 (xx)
MX (1)	MXPA01011562A (xx)
MY (1)	MY164077A (xx)
NL (1)	NL300337I2 (xx)
NO (2)	NO324564B1 (xx)
NZ (1)	NZ515423A (xx)
PL (1)	PL198185B1 (xx)
PT (3)	PT1702618E (xx)
SI (3)	SI1716853T1 (xx)
SK (1)	SK287580B6 (xx)
TR (1)	TR200103819T2 (xx)
UA (1)	UA74782C2 (xx)
WO (1)	WO2000069441A1 (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY164077A (en)	1999-05-13	2017-11-30	Pharma Mar Sa	Compositions and uses of et743 for treating cancer
MXPA02011319A (es)	2000-05-15	2003-06-06	Pharma Mar Sa	Analogos antitumorales de ecteinascidina 743.
CA2428160C (en) *	2000-11-06	2009-10-13	Pharma Mar, S.A.	Compositions for antitumor treatment containing ecteinascidin 743
GB0117402D0 (en) *	2001-07-17	2001-09-05	Pharma Mar Sa	New antitumoral derivatives of et-743
IL161430A0 (en) *	2001-10-19	2004-09-27	Pharma Mar Sa	Pharmaceutical compositions containing ecteinascidin 743
GB0202544D0 (en)	2002-02-04	2002-03-20	Pharma Mar Sa	The synthesis of naturally occuring ecteinascidins and related compounds
GB0324201D0 (en) *	2003-10-15	2003-11-19	Pharma Mar Sau	Improved antitumoral combinations
DK1689404T3 (da) *	2003-11-13	2009-01-26	Pharma Mar Sau	Kombination af et-743 med 5-fluoracil-prodrugs til behandling af cancer
WO2005049030A1 (en) *	2003-11-14	2005-06-02	Pharma Mar, S.A.	Combination therapy comprising the use of et-743 and paclitaxel for treating cancer
GB0326486D0 (en) *	2003-11-14	2003-12-17	Pharma Mar Sau	Combination treatment
WO2006005602A2 (en) *	2004-07-09	2006-01-19	Pharma Mar, S.A.	Use of ecteinascidin in the treatment of cancer in patients with low level of brca1
NZ554765A (en) *	2004-10-26	2010-01-29	Pharma Mar Sa	Pegylated Liposomal Doxorubicin In Combination With Ecteinescidin 743
ATE368461T1 (de) *	2004-10-29	2007-08-15	Pharma Mar Sa	Zusammensetzungen enthaltend ecteinascidin und einen disaccharide
GB0522082D0 (en) *	2005-10-31	2005-12-07	Pharma Mar Sa	Formulations
JP2009536956A (ja) *	2006-05-12	2009-10-22	ファルマ・マール・ソシエダード・アノニマ	抗癌治療法
AU2008313634A1 (en) *	2007-10-19	2009-04-23	Pharma Mar, S.A.	Prognostic molecular markers for ET-743 treatment
WO2017133544A1 (zh) *	2016-02-04	2017-08-10	江苏恒瑞医药股份有限公司	一种曲贝替定的可注射胃肠外用药物组合物及其制备方法
JOP20190254A1 (ar)	2017-04-27	2019-10-27	Pharma Mar Sa	مركبات مضادة للأورام
WO2020239478A1 (en)	2019-05-28	2020-12-03	Pharma Mar, S.A.	Trabectedin for treating sarcomas based on genomic markers
CN112574234B (zh) *	2019-09-27	2022-05-24	江苏恒瑞医药股份有限公司	一种海鞘素衍生物的制备方法
EP4041194B1 (en)	2020-04-15	2024-03-13	EVER Valinject GmbH	Composition comprising trabectedin and an amino acid
US20230226051A1 (en)	2022-01-20	2023-07-20	Extrovis Ag	Trabectedin composition

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1987007610A2 (en) *	1986-06-09	1987-12-17	University Of Illinois	Ecteinascidins 729, 743, 745, 759a, 759b and 770
US5089273A (en)	1986-06-09	1992-02-18	Board Of Trustees Of The University Of Illinois	Ecteinascidins 729, 743, 745, 759A, 759B and 770
US5256663A (en)	1986-06-09	1993-10-26	The Board Of Trustees Of The University Of Illinois	Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith
US5149804A (en)	1990-11-30	1992-09-22	The Board Of Trustees Of The University Of Illinois	Ecteinascidins 736 and 722
DE3635711A1 (de)	1986-10-21	1988-04-28	Knoll Ag	5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung
GB8805268D0 (en) *	1988-03-04	1988-04-07	Glaxo Group Ltd	Medicaments
GB9101221D0 (en) *	1991-01-19	1991-02-27	Smithkline Beecham Plc	Pharmaceuticals
US5721352A (en)	1991-02-19	1998-02-24	University Of Florida Research Foundation	Entomopoxvirus expression system
FR2697752B1 (fr)	1992-11-10	1995-04-14	Rhone Poulenc Rorer Sa	Compositions antitumorales contenant des dérivés du taxane.
US5891704A (en) *	1992-11-19	1999-04-06	Anticancer, Inc.	Method to produce high levels of methioninase
WO1994026250A1 (en) *	1993-05-14	1994-11-24	Depotech Corporation	Method for treating neurological disorders
US5478932A (en) *	1993-12-02	1995-12-26	The Board Of Trustees Of The University Of Illinois	Ecteinascidins
US20040059112A1 (en)	1994-02-18	2004-03-25	Rinehart Kenneth L.	Ecteinascidins
US5919816A (en) *	1994-11-14	1999-07-06	Bionumerik Pharmaceuticals, Inc.	Formulations and methods of reducing toxicity of antineoplastic agents
GB9508195D0 (en)	1995-04-20	1995-06-07	Univ British Columbia	Novel biologically active compounds and compositions,their use and derivation
US5721362A (en) *	1996-09-18	1998-02-24	President And Fellows Of Harvard College	Process for producing ecteinascidin compounds
DK1586322T3 (da) *	1996-11-05	2008-12-01	Childrens Medical Center	Sammensætninger indeholdende thalidomid og dextamethason til behandling af cancer
IL123740A0 (en) *	1997-03-28	1998-10-30	Pfizer	NK-1 receptor antagonists for the treatment of delayed emesis
US5985876A (en)	1997-04-15	1999-11-16	Univ Illinois	Nucleophile substituted ecteinascidins and N-oxide ecteinascidins
DE19720312A1 (de) *	1997-05-15	1998-11-19	Hoechst Ag	Zubereitung mit erhöhter in vivo Verträglichkeit
GB9801231D0 (en) *	1997-06-05	1998-03-18	Merck & Co Inc	A method of treating cancer
RU2217432C2 (ru)	1998-04-06	2003-11-27	Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Иллинойс	Эктеинасцидины, фармацевтическая композиция, содержащая их и способ лечения опухолей
NZ508585A (en) *	1998-05-11	2002-11-26	Pharma Mar S	Metabolites of ecteinascidin 743
US6124292A (en)	1998-09-30	2000-09-26	President And Fellows Of Harvard College	Synthetic analogs of ecteinascidin-743
MY164077A (en)	1999-05-13	2017-11-30	Pharma Mar Sa	Compositions and uses of et743 for treating cancer
AR035842A1 (es)	1999-05-14	2004-07-21	Pharma Mar Sa	Metodo de hemisintesis para la formacion de compuestos intermediarios y derivados y de estructuras relacionadas con la ecteinascidina y de tetrahidroisoquinolinfenoles y compuestos intermediarios de aplicacion en dicho metodo
WO2001077115A1 (en)	2000-04-12	2001-10-18	Pharma Mar, S.A.	Antitumoral ecteinascidin derivatives
US7247892B2 (en)	2000-04-24	2007-07-24	Taylor Geoff W	Imaging array utilizing thyristor-based pixel elements
MXPA02011319A (es)	2000-05-15	2003-06-06	Pharma Mar Sa	Analogos antitumorales de ecteinascidina 743.
US7420051B2 (en)	2000-05-15	2008-09-02	Pharma Mar, S.A.	Synthetic process for the manufacture of an ecteinaschidin compound
CA2418320A1 (en)	2000-08-11	2002-02-21	City Of Hope	The anti-neoplastic agent et-743 inhibits trans activation by sxr
CA2428160C (en)	2000-11-06	2009-10-13	Pharma Mar, S.A.	Compositions for antitumor treatment containing ecteinascidin 743
WO2002064843A1 (en)	2001-02-09	2002-08-22	The Regents Of The University Of California	Ecteinascidin family compounds: compositions and methods
EP1372658A2 (en)	2001-03-30	2004-01-02	Shire Biochem Inc.	Methods of treating cancer using cyplastin combined with a dioxolane nucleoside such as troxacitabine
GB0121285D0 (en)	2001-09-03	2001-10-24	Cancer Res Ventures Ltd	Anti-cancer combinations
IL161430A0 (en)	2001-10-19	2004-09-27	Pharma Mar Sa	Pharmaceutical compositions containing ecteinascidin 743
US20040019027A1 (en)	2002-04-12	2004-01-29	Barry Forman	Method of treating cerebrotendinous xanthomatosis
GB0312407D0 (en)	2003-05-29	2003-07-02	Pharma Mar Sau	Treatment
GB0324201D0 (en)	2003-10-15	2003-11-19	Pharma Mar Sau	Improved antitumoral combinations
DK1689404T3 (da)	2003-11-13	2009-01-26	Pharma Mar Sau	Kombination af et-743 med 5-fluoracil-prodrugs til behandling af cancer
WO2005049030A1 (en)	2003-11-14	2005-06-02	Pharma Mar, S.A.	Combination therapy comprising the use of et-743 and paclitaxel for treating cancer
GB0326486D0 (en)	2003-11-14	2003-12-17	Pharma Mar Sau	Combination treatment
WO2006005602A2 (en)	2004-07-09	2006-01-19	Pharma Mar, S.A.	Use of ecteinascidin in the treatment of cancer in patients with low level of brca1
EP1812114A2 (en)	2004-09-29	2007-08-01	Pharma Mar S.A., Sociedad Unipersonal	Ecteinascidin compounds as anti-inflammatory agents
NZ554765A (en)	2004-10-26	2010-01-29	Pharma Mar Sa	Pegylated Liposomal Doxorubicin In Combination With Ecteinescidin 743
ATE368461T1 (de)	2004-10-29	2007-08-15	Pharma Mar Sa	Zusammensetzungen enthaltend ecteinascidin und einen disaccharide
CA2630900A1 (en)	2005-11-25	2007-05-31	University Of Medicine And Dentistry Of New Jersey	Use of parp-1 inhibitors
JP2009536956A (ja)	2006-05-12	2009-10-22	ファルマ・マール・ソシエダード・アノニマ	抗癌治療法

2000
- 2000-05-13 MY MYPI20002107A patent/MY164077A/en unknown
- 2000-05-15 DE DE60030554T patent/DE60030554T8/de active Active
- 2000-05-15 SI SI200031067T patent/SI1716853T1/sl unknown
- 2000-05-15 SI SI200030977T patent/SI1702618T1/sl unknown
- 2000-05-15 AT AT06011784T patent/ATE375795T1/de active
- 2000-05-15 DK DK00927584T patent/DK1176964T3/da active
- 2000-05-15 PT PT06011784T patent/PT1702618E/pt unknown
- 2000-05-15 DK DK06011784T patent/DK1702618T3/da active
- 2000-05-15 AT AT06014005T patent/ATE500830T1/de active
- 2000-05-15 WO PCT/GB2000/001857 patent/WO2000069441A1/en active IP Right Grant
- 2000-05-15 CN CN00809976A patent/CN1360503A/zh active Pending
- 2000-05-15 EP EP06014005A patent/EP1716853B9/en not_active Expired - Lifetime
- 2000-05-15 AU AU45975/00A patent/AU777417B2/en not_active Expired
- 2000-05-15 CN CNB2005100091622A patent/CN100477993C/zh not_active Expired - Lifetime
- 2000-05-15 DE DE60036826T patent/DE60036826T2/de not_active Expired - Lifetime
- 2000-05-15 EP EP00927584A patent/EP1176964B8/en not_active Expired - Lifetime
- 2000-05-15 CA CA002373794A patent/CA2373794C/en not_active Expired - Lifetime
- 2000-05-15 UA UA2001128559A patent/UA74782C2/uk unknown
- 2000-05-15 PL PL352931A patent/PL198185B1/pl unknown
- 2000-05-15 AR ARP000102321A patent/AR028476A1/es not_active Application Discontinuation
- 2000-05-15 IL IL14643400A patent/IL146434A0/xx active IP Right Grant
- 2000-05-15 DK DK06014005.0T patent/DK1716853T3/da active
- 2000-05-15 CZ CZ20014081A patent/CZ301482B6/cs not_active IP Right Cessation
- 2000-05-15 TR TR2001/03819T patent/TR200103819T2/xx unknown
- 2000-05-15 AT AT00927584T patent/ATE338552T1/de active
- 2000-05-15 ES ES06011784T patent/ES2294756T3/es not_active Expired - Lifetime
- 2000-05-15 JP JP2000617900A patent/JP2002544231A/ja not_active Withdrawn
- 2000-05-15 NZ NZ515423A patent/NZ515423A/en not_active IP Right Cessation
- 2000-05-15 MX MXPA01011562A patent/MXPA01011562A/es active IP Right Grant
- 2000-05-15 BR BR0010531-7A patent/BR0010531A/pt not_active Application Discontinuation
- 2000-05-15 PT PT06014005T patent/PT1716853E/pt unknown
- 2000-05-15 DE DE60045720T patent/DE60045720D1/de not_active Expired - Lifetime
- 2000-05-15 EP EP06011784A patent/EP1702618B1/en not_active Expired - Lifetime
- 2000-05-15 HU HU0201187A patent/HU229866B1/hu active Protection Beyond IP Right Term
- 2000-05-15 DE DE122008000013C patent/DE122008000013I1/de active Pending
- 2000-05-15 SI SI200030905T patent/SI1176964T1/sl unknown
- 2000-05-15 SK SK1644-2001A patent/SK287580B6/sk not_active IP Right Cessation
- 2000-05-15 KR KR1020017014479A patent/KR20020019914A/ko active Search and Examination
- 2000-05-15 PT PT00927584T patent/PT1176964E/pt unknown
- 2000-05-15 ES ES00927584T patent/ES2272279T3/es not_active Expired - Lifetime
2001
- 2001-11-11 IL IL146434A patent/IL146434A/en active Protection Beyond IP Right Term
- 2001-11-12 NO NO20015516A patent/NO324564B1/no not_active IP Right Cessation
- 2001-12-03 BG BG106171A patent/BG65680B1/bg unknown
2005
- 2005-01-14 AU AU2005200180A patent/AU2005200180B9/en not_active Expired
2006
- 2006-11-30 CY CY20061101734T patent/CY1105818T1/el unknown
2007
- 2007-06-28 US US11/769,873 patent/US8119638B2/en not_active Expired - Fee Related
2008
- 2008-01-16 CY CY20081100059T patent/CY1107143T1/el unknown
- 2008-02-22 NL NL300337C patent/NL300337I2/nl unknown
- 2008-03-10 LU LU91418C patent/LU91418I2/fr unknown
- 2008-04-07 CY CY200800007C patent/CY2008007I2/el unknown
- 2008-04-16 FR FR08C0013C patent/FR08C0013I2/fr active Active
- 2008-05-16 NO NO2008005C patent/NO2008005I1/no not_active IP Right Cessation
2011
- 2011-06-08 CY CY20111100545T patent/CY1112753T1/el unknown
2012
- 2012-05-02 JP JP2012105249A patent/JP5777562B2/ja not_active Expired - Lifetime
2015
- 2015-01-06 HU HUS1500001C patent/HUS1500001I1/hu unknown

Also Published As

Publication number	Publication date
CY1105818T1 (el)	2011-02-02
BR0010531A (pt)	2002-06-04
CY1107143T1 (el)	2010-07-28
DE60030554T2 (de)	2007-09-13
AU4597500A (en)	2000-12-05
WO2000069441A1 (en)	2000-11-23
LU91418I2 (fr)	2008-05-13
DK1176964T3 (da)	2007-01-15
PL352931A1 (en)	2003-09-22
SI1702618T1 (sl)	2008-02-29
CY1112753T1 (el)	2016-02-10
EP1176964B8 (en)	2007-10-10
KR20020019914A (ko)	2002-03-13
EP1716853A3 (en)	2006-11-15
UA74782C2 (uk)	2006-02-15
NO20015516L (no)	2002-01-11
AU2005200180B2 (en)	2007-12-13
NZ515423A (en)	2004-04-30
MY164077A (en)	2017-11-30
PT1716853E (pt)	2011-05-12
IL146434A (en)	2008-03-20
CY2008007I1 (el)	2009-11-04
HU229866B1 (en)	2014-10-28
CY2008007I2 (el)	2009-11-04
CA2373794C (en)	2005-10-11
ATE375795T1 (de)	2007-11-15
HUP0201187A3 (en)	2002-11-28
CN1679631A (zh)	2005-10-12
NL300337I1 (nl)	2008-05-01
ATE500830T1 (de)	2011-03-15
DE60030554T8 (de)	2008-01-10
HUP0201187A2 (en)	2002-09-28
AR028476A1 (es)	2003-05-14
PT1702618E (pt)	2008-01-11
EP1176964B1 (en)	2006-09-06
PT1176964E (pt)	2007-01-31
SI1716853T1 (sl)	2011-10-28
ES2294756T3 (es)	2008-04-01
AU777417B2 (en)	2004-10-14
EP1702618A3 (en)	2006-12-27
EP1702618B1 (en)	2007-10-17
DK1702618T3 (da)	2008-02-25
FR08C0013I2 (fr)	2009-10-30
EP1716853B9 (en)	2011-09-28
JP2012149095A (ja)	2012-08-09
HUS1500001I1 (hu)	2016-08-29
LU91418I9 (xx)	2019-01-02
NO20015516D0 (no)	2001-11-12
US20070275942A1 (en)	2007-11-29
SI1176964T1 (sl)	2007-02-28
DE60045720D1 (de)	2011-04-21
AU2005200180B9 (en)	2008-05-29
CZ301482B6 (cs)	2010-03-17
PL198185B1 (pl)	2008-06-30
AU2005200180A1 (en)	2005-02-10
ATE338552T1 (de)	2006-09-15
DE60030554D1 (de)	2006-10-19
FR08C0013I1 (xx)	2008-05-30
CZ20014081A3 (cs)	2002-11-13
NO324564B1 (no)	2007-11-19
EP1716853A2 (en)	2006-11-02
NL300337I2 (nl)	2008-09-01
EP1176964A1 (en)	2002-02-06
NO2008005I2 (xx)	2010-09-27
DK1716853T3 (da)	2011-06-27
SK16442001A3 (sk)	2002-03-05
CA2373794A1 (en)	2000-11-23
CN1360503A (zh)	2002-07-24
DE60036826T2 (de)	2008-08-28
DE122008000013I1 (de)	2008-08-07
JP2002544231A (ja)	2002-12-24
TR200103819T2 (tr)	2002-04-22
EP1716853B1 (en)	2011-03-09
EP1702618A2 (en)	2006-09-20
US8119638B2 (en)	2012-02-21
NO2008005I1 (no)	2008-06-09
BG106171A (en)	2002-06-28
ES2272279T3 (es)	2007-05-01
JP5777562B2 (ja)	2015-09-09
CN100477993C (zh)	2009-04-15
MXPA01011562A (es)	2002-07-30
SK287580B6 (sk)	2011-03-04
BG65680B1 (bg)	2009-06-30
DE60036826D1 (de)	2007-11-29

Legal Events

Date	Code	Title
2008-11-03	FF	Patent granted
2009-02-11	KB	Patent renewed
2010-04-14	KB	Patent renewed

Publication	Publication Date	Title
HUP0203378A3 (en)	2004-07-28	Pharmaceutical compounds and pharmaceutical compositions containing them
HUP0203939A3 (en)	2004-12-28	Pharmaceutical compounds and compositions containing them and their use
IL148517A0 (en)	2002-09-12	Heterocyclic compounds and pharmaceutical compositions containing the same
IL149138A0 (en)	2002-11-10	Pharmaceutical compositions containing metformin
IL150077A0 (en)	2002-12-01	Heterocyclic compounds and pharmaceutical compositions containing the same
HUP0202513A2 (en)	2002-10-28	Betha-carboline pharmaceutical compositions
PL351387A1 (en)	2003-04-07	Pharmaceutical composition
GB0028088D0 (en)	2001-01-03	Pharmaceutical compositions
GB0001662D0 (en)	2000-03-15	Pharmaceutical compositions
IL144910A0 (en)	2002-06-30	Cyclic compounds and pharmaceutical compositions containing the same
HUP0103256A3 (en)	2002-05-28	Thiobenzimidazole derivatives and pharmaceutical compositions containing the compounds
IL146434A0 (en)	2002-07-25	Pharmaceutical compositions containing ecteinascidin 743
HK1044476A1 (en)	2002-10-25	Medicinal compositions
IL161430A0 (en)	2004-09-27	Pharmaceutical compositions containing ecteinascidin 743
IL152094A0 (en)	2003-05-29	Ecteinascidin derivatives and pharmaceutical compositions containing the same
GB9923436D0 (en)	1999-12-08	Pharmaceutical compositions
EP1166786A4 (en)	2004-05-12	MEDICAL COMPOSITIONS
IL149883A0 (en)	2002-11-10	Heterocyclic compounds and pharmaceutical compositions containing the same
HUP0201714A2 (en)	2002-10-28	Substituted heterocyclic compounds and pharmaceutical compositions containing them
HUP0000137A3 (en)	2001-03-28	Controller-release pharmaceutical composition containing anangetics
HUP0200747A2 (en)	2002-06-29	Pharmaceutical compounds and pharmaceutical compositions containing them
GB9904163D0 (en)	1999-04-14	Pharmaceutical compositions
IL148691A0 (en)	2002-09-12	Pharmaceutical compositions containing ciclesonide
GB2363572B (en)	2004-02-18	Pharmaceutical composition containing cyclosporin
GB9911017D0 (en)	1999-07-14	Pharmaceutical compositions