IL139865A0 - A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same - Google Patents

A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same

Info

Publication number
IL139865A0
IL139865A0 IL13986599A IL13986599A IL139865A0 IL 139865 A0 IL139865 A0 IL 139865A0 IL 13986599 A IL13986599 A IL 13986599A IL 13986599 A IL13986599 A IL 13986599A IL 139865 A0 IL139865 A0 IL 139865A0
Authority
IL
Israel
Prior art keywords
same
pharmaceutical compositions
compositions containing
selective glucocorticoid
glucocorticoid antagonist
Prior art date
Application number
IL13986599A
Other languages
English (en)
Original Assignee
Karobio Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9812314.4A external-priority patent/GB9812314D0/en
Priority claimed from GBGB9815149.1A external-priority patent/GB9815149D0/en
Application filed by Karobio Ab filed Critical Karobio Ab
Publication of IL139865A0 publication Critical patent/IL139865A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13986599A 1998-06-08 1999-06-07 A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same IL139865A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9812314.4A GB9812314D0 (en) 1998-06-08 1998-06-08 Treatment of diabetes
GBGB9815149.1A GB9815149D0 (en) 1998-07-13 1998-07-13 Treatment of diabetes
PCT/IB1999/001175 WO1999063976A2 (en) 1998-06-08 1999-06-07 Liver-selective glucocorticoid antagonist for treating diabetes

Publications (1)

Publication Number Publication Date
IL139865A0 true IL139865A0 (en) 2002-02-10

Family

ID=26313822

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13986599A IL139865A0 (en) 1998-06-08 1999-06-07 A liver selective glucocorticoid antagonist and pharmaceutical compositions containing the same

Country Status (7)

Country Link
EP (1) EP1143948A3 (de)
JP (1) JP2002527355A (de)
KR (1) KR20010052431A (de)
AU (1) AU751569B2 (de)
CA (1) CA2334116A1 (de)
IL (1) IL139865A0 (de)
WO (1) WO1999063976A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9816935D0 (en) * 1998-08-05 1998-09-30 Karobio Ab Novel glucocortoid and thyroid receptor ligands for the treatment of metabolic disorders
GB9907048D0 (en) 1999-03-27 1999-05-19 Karobio Ab Novel glucocorticoid receptor ligands for the treatment of meta bolic disorders
GB9928805D0 (en) * 1999-12-07 2000-02-02 Karobio Ab Compounds active at the Glucocorticoid and Thyroid Hormone Receptors
ES2246292T3 (es) 2000-10-30 2006-02-16 Pfizer Products Inc. Moduladores de receptor glucocorticoide.
GB0029100D0 (en) * 2000-11-29 2001-01-10 Karobio Ab Compounds active at the glucocorticoid receptor
GB0029102D0 (en) 2000-11-29 2001-01-10 Karobio Ab Compounds active at the glucocorticoid receptor
JP2004519439A (ja) * 2000-12-20 2004-07-02 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト グルココルチコイド関連副作用の治療用の解離したグルココルチコイドレセプターアンタゴニスト
US6583180B2 (en) 2001-02-14 2003-06-24 Abbott Laboratories Glucocorticoid receptor modulators
ATE437853T1 (de) * 2001-02-14 2009-08-15 Karobio Ab Glucocorticoid-rezeptoren-modulatoren
EP1285927A3 (de) 2001-08-16 2005-06-29 Schering Aktiengesellschaft Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems
WO2003059253A2 (en) * 2001-12-21 2003-07-24 Smithkline Beecham Corporation Compositions and methods for altering glucose production
MXPA04009329A (es) 2002-03-26 2005-01-25 Boehringer Ingelheim Pharma Mimeticos de glucocorticoides, metodos para su preparacion, composiciones farmaceuticas y usos de los mismos.
US7186864B2 (en) 2002-05-29 2007-03-06 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7074806B2 (en) 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US8097606B2 (en) 2003-07-23 2012-01-17 Corcept Therapeutics, Inc. Antiglucocorticoids for the treatment of catatonia
US7527829B2 (en) 2003-07-31 2009-05-05 Soken Chemical & Engineering Co., Ltd. Fluid colloid crystal and process for producing three-dimensional aligned particle mass therefrom
UY28526A1 (es) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
US7741361B2 (en) 2004-12-27 2010-06-22 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
WO2008070507A2 (en) 2006-12-06 2008-06-12 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
AU2009256289A1 (en) 2008-06-06 2009-12-10 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US8138189B2 (en) * 2009-03-26 2012-03-20 Hoffman-La Roche Inc. Substituted benzene compounds as modulators of the glucocorticoid receptor
EP2459524A2 (de) 2009-07-31 2012-06-06 Cadila Healthcare Limited Neuartige verbindungen als glucocorticoidrezeptor-modulatoren

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374148A (en) * 1980-10-21 1983-02-15 Pfizer Inc. Carboxylic acid therapeutic agents
WO1998027986A1 (en) * 1996-12-24 1998-07-02 Zymogenetics, Inc. Treatment agents and methods for treating type ii diabetes and symptoms of type ii diabetes

Also Published As

Publication number Publication date
AU4160699A (en) 1999-12-30
KR20010052431A (ko) 2001-06-25
AU751569B2 (en) 2002-08-22
CA2334116A1 (en) 1999-12-16
JP2002527355A (ja) 2002-08-27
EP1143948A3 (de) 2002-09-11
EP1143948A2 (de) 2001-10-17
WO1999063976A3 (en) 2001-12-20
WO1999063976A2 (en) 1999-12-16

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