IL139385A - Labelled glutamine and lysine analogues, metal complexes thereof, and uses thereof for diagnosis - Google Patents

Labelled glutamine and lysine analogues, metal complexes thereof, and uses thereof for diagnosis

Info

Publication number
IL139385A
IL139385A IL13938599A IL13938599A IL139385A IL 139385 A IL139385 A IL 139385A IL 13938599 A IL13938599 A IL 13938599A IL 13938599 A IL13938599 A IL 13938599A IL 139385 A IL139385 A IL 139385A
Authority
IL
Israel
Prior art keywords
diagnosis
metal complexes
labelled
glutamine
lysine analogues
Prior art date
Application number
IL13938599A
Other languages
English (en)
Other versions
IL139385A0 (en
Original Assignee
Amersham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Plc filed Critical Amersham Plc
Publication of IL139385A0 publication Critical patent/IL139385A0/xx
Publication of IL139385A publication Critical patent/IL139385A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL13938599A 1998-05-15 1999-05-14 Labelled glutamine and lysine analogues, metal complexes thereof, and uses thereof for diagnosis IL139385A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98303872 1998-05-15
PCT/GB1999/001550 WO1999060018A1 (en) 1998-05-15 1999-05-14 Labelled glutamine and lysine analogues

Publications (2)

Publication Number Publication Date
IL139385A0 IL139385A0 (en) 2001-11-25
IL139385A true IL139385A (en) 2005-09-25

Family

ID=8234827

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13938599A IL139385A (en) 1998-05-15 1999-05-14 Labelled glutamine and lysine analogues, metal complexes thereof, and uses thereof for diagnosis

Country Status (17)

Country Link
US (2) US7049289B1 (zh)
EP (1) EP1077998B1 (zh)
JP (2) JP4199420B2 (zh)
KR (1) KR100660509B1 (zh)
CN (2) CN101407543A (zh)
AT (1) ATE384075T1 (zh)
AU (1) AU762736B2 (zh)
BR (1) BR9910468A (zh)
CA (1) CA2332277A1 (zh)
DE (1) DE69937996T2 (zh)
ES (1) ES2299245T3 (zh)
HU (1) HUP0102154A3 (zh)
IL (1) IL139385A (zh)
NO (1) NO20005751L (zh)
RU (1) RU2205186C2 (zh)
WO (1) WO1999060018A1 (zh)
ZA (1) ZA200006313B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002239655A1 (en) * 2001-01-05 2002-07-16 Duke University Contrast enhancement agent for magnetic resonance imaging
PL207834B1 (pl) * 2001-07-10 2011-02-28 Ge Healthcare As Związki na bazie peptydów, ich zastosowanie oraz zawierająca je kompozycja farmaceutyczna
GB0116815D0 (en) 2001-07-10 2001-08-29 Nycomed Amersham Plc Improved chelator conjugates
GB0223249D0 (en) * 2002-10-08 2002-11-13 Amersham Plc Improved imaging agents
GB0224799D0 (en) * 2002-10-25 2002-12-04 Amersham Plc Improved complex compositions
WO2004106939A2 (en) * 2003-06-03 2004-12-09 Paul Scherrer Institut Method for the linkage of bifunctional chelating agents and (radioactive) transition metal complexes to proteins and peptides
GB0515974D0 (en) * 2005-08-03 2005-09-07 Ge Healthcare Ltd Compounds and imaging methods
JP5635225B2 (ja) 2005-11-29 2014-12-03 日本メジフィジックス株式会社 放射性ハロゲン標識有機化合物の前駆体化合物
WO2008060368A2 (en) * 2006-10-02 2008-05-22 Duke University Transglutaminase-binding peptides and methods of use
US20130195756A1 (en) * 2012-01-31 2013-08-01 General Electric Company 99mTc IMAGING AGENTS AND METHODS OF USE
EP3027228A4 (en) 2013-08-01 2017-06-07 Rochester Institute of Technology Modular imaging agents containing amino acids and peptides
GB201610176D0 (en) * 2016-06-10 2016-07-27 Edinburgh Molecular Imaging Ltd Imaging agents and methods of use
US11162129B2 (en) * 2016-11-09 2021-11-02 IsoPlexis Corporation Photoprotective mixtures as imaging reagents in sequencing-by-synthesis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59186947A (ja) * 1983-03-09 1984-10-23 Kowa Co 新規ペプチド
EP0325639A4 (en) * 1987-07-07 1990-10-24 Cytrx Biopool Ltd. Fibrin-binding compound and method
US5270030A (en) * 1988-12-29 1993-12-14 Bio-Technology General Corp. Fibrin binding domain polypeptide and method of producing
DK0629133T3 (da) * 1992-01-03 2001-04-02 Rhomed Inc Farmaceutisk anvendelse af peptidmetalioner
US5608110A (en) * 1993-06-15 1997-03-04 Bracco International B.V. Heteroatom-bearing ligands and metal complexes thereof
US6653299B1 (en) * 1997-01-21 2003-11-25 Nycomed Amersham Plc Labelled factor XIIIa substrates

Also Published As

Publication number Publication date
EP1077998B1 (en) 2008-01-16
JP4199420B2 (ja) 2008-12-17
AU762736B2 (en) 2003-07-03
DE69937996D1 (de) 2008-03-06
CA2332277A1 (en) 1999-11-25
HUP0102154A2 (hu) 2001-09-28
EP1077998A1 (en) 2001-02-28
CN101407543A (zh) 2009-04-15
US7049289B1 (en) 2006-05-23
ZA200006313B (en) 2002-07-17
KR20010043608A (ko) 2001-05-25
AU3942899A (en) 1999-12-06
RU2205186C2 (ru) 2003-05-27
KR100660509B1 (ko) 2006-12-22
ATE384075T1 (de) 2008-02-15
WO1999060018A1 (en) 1999-11-25
HUP0102154A3 (en) 2009-01-28
DE69937996T2 (de) 2009-01-02
JP2002515510A (ja) 2002-05-28
NO20005751D0 (no) 2000-11-14
NO20005751L (no) 2001-01-08
BR9910468A (pt) 2001-01-09
JP2006137751A (ja) 2006-06-01
ES2299245T3 (es) 2008-05-16
US20060292075A1 (en) 2006-12-28
IL139385A0 (en) 2001-11-25
CN1309661A (zh) 2001-08-22

Similar Documents

Publication Publication Date Title
IL139385A (en) Labelled glutamine and lysine analogues, metal complexes thereof, and uses thereof for diagnosis
GR3026665T3 (en) Dual action inhibitors.
AU8188987A (en) Improved metal complex-containing pharmaceutical agents
HU9503174D0 (en) 2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
IL140437A0 (en) Pharmaceutical compositions comprising 2-quinolines
NO960724L (no) Middel for transdermal applisering inneholdende gestodenestere
GEP20074185B (en) Incclusion complexs of aryl- heterocyclic salts
EP0723602A4 (zh)
BG101851A (en) Hepatitis vaccine
BG103995A (en) Reverse hydroxamate inhibitors of matrix metalloprreverse hydroxamate inhibitors of matrix metallprooteinases teinases
SG168401A1 (en) Catalyst and use thereof
NZ334854A (en) Foliar fertilisers including trace element compounds
GR3032287T3 (en) Sprout inhibitor for potatoes.
TW349000B (en) Fungicidal two-component composition based on R-metalaxyl and usage thereof
CA2481593A1 (en) Biologically stable liquid composition of fviii, of vwf or of fviii/vwf complex of human origin
SE7910541L (sv) Ferritisk fe-mn-legering for kryogena applikationer
HU9601031D0 (en) Ibuprofen and flurbiprofen as anti-pruritic agents
DE59808546D1 (de) Verwendung von fettsäureniedrigalkylestern in abbeizmitteln
ES2153425T3 (es) Sulfato de tris(isonitrilo)cobre(i) para preparar complejos de radio nuclidos.
ATE261124T1 (de) Biotin-peg-substrat für einen lipase-assay
ATE232111T1 (de) Polyrotaxane
MY122562A (en) Antibacterial composition
EP0884378A3 (en) Friction modifier compound and lubricating oil composition containing the same
ZA982808B (en) Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia
UA23145A (uk) Спосіб визhачеhhя активhості бромелаїhу

Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees