IL134978A0 - Membrane virus host range mutations and their uses as vaccine substrates - Google Patents

Membrane virus host range mutations and their uses as vaccine substrates

Info

Publication number
IL134978A0
IL134978A0 IL13497898A IL13497898A IL134978A0 IL 134978 A0 IL134978 A0 IL 134978A0 IL 13497898 A IL13497898 A IL 13497898A IL 13497898 A IL13497898 A IL 13497898A IL 134978 A0 IL134978 A0 IL 134978A0
Authority
IL
Israel
Prior art keywords
membrane
membranes
vaccine
viruses
proteins
Prior art date
Application number
IL13497898A
Other languages
English (en)
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of IL134978A0 publication Critical patent/IL134978A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36161—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL13497898A 1997-09-18 1998-09-18 Membrane virus host range mutations and their uses as vaccine substrates IL134978A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5966897P 1997-09-18 1997-09-18
PCT/US1998/019556 WO1999013818A2 (en) 1997-09-18 1998-09-18 Membrane virus host range mutations and their uses as vaccine substrates

Publications (1)

Publication Number Publication Date
IL134978A0 true IL134978A0 (en) 2001-05-20

Family

ID=22024455

Family Applications (2)

Application Number Title Priority Date Filing Date
IL13497898A IL134978A0 (en) 1997-09-18 1998-09-18 Membrane virus host range mutations and their uses as vaccine substrates
IL134978A IL134978A (en) 1997-09-18 2000-03-09 Mutations in membranous viruses that affect the range of surrogates and use of viruses as immune substances

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL134978A IL134978A (en) 1997-09-18 2000-03-09 Mutations in membranous viruses that affect the range of surrogates and use of viruses as immune substances

Country Status (16)

Country Link
US (1) US6306401B1 (de)
EP (1) EP1037603B1 (de)
JP (1) JP4318399B2 (de)
KR (1) KR20010024148A (de)
CN (1) CN1284859C (de)
AT (1) ATE345813T1 (de)
AU (1) AU737088B2 (de)
CA (1) CA2302809C (de)
DE (1) DE69836499T2 (de)
HK (1) HK1033544A1 (de)
IL (2) IL134978A0 (de)
NZ (1) NZ503128A (de)
RU (1) RU2218403C2 (de)
TW (1) TW589381B (de)
WO (1) WO1999013818A2 (de)
ZA (1) ZA988446B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7335363B2 (en) * 1997-09-18 2008-02-26 Research Development Foundation Membrane virus host range mutations and their uses as vaccine substrates
US6589533B1 (en) * 1997-09-18 2003-07-08 Research Development Foundation Genetically-engineered alphaviruses, flaviviruses, and bunyaviruses with modified envelope transmembrane glycoproteins and altered host-range phenotype
US7128915B2 (en) * 1997-09-18 2006-10-31 Research Development Foundation Membrane virus host range mutations and their uses as vaccine substrates
EP1100944A1 (de) * 1998-07-30 2001-05-23 The Johns Hopkins University School Of Medicine Zielgerichteter alphavirus und vektoren der alphavirus
EP2963118B1 (de) * 2005-06-01 2017-08-09 California Institute of Technology Verfahren zur gezielten genabgabe über virale vektoren
CN100427918C (zh) * 2006-06-05 2008-10-22 中国科学院南海海洋研究所 一种海水鱼类卵子电镜扫描样品制备方法
EP2526774A3 (de) 2006-07-21 2013-03-06 California Institute of Technology Zielgesteuerte Genabgabe für die Immunisierung mit Dendritenzellen
SI2770061T1 (sl) 2009-07-24 2019-02-28 Immune Design Corp. Neintegrirani lentiviralni vektorji
WO2011119628A2 (en) 2010-03-23 2011-09-29 The Regents Of The University Of California Compositions and methods for self-adjuvanting vaccines against microbes and tumors
BR112012024224A2 (pt) * 2010-03-24 2016-11-29 Arbovax Inc mutações da faixa de hospedeiro de flavivírus e seu uso.
US8889148B2 (en) 2010-07-01 2014-11-18 Research Development Foundation Flavivirus host-range mutations and uses thereof
US9713635B2 (en) 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
US8323662B1 (en) 2012-03-30 2012-12-04 Immune Design Corp. Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
PT2831095T (pt) 2012-03-30 2019-01-30 Immune Design Corp Partículas de vectores lentivirais com melhor eficácia de transdução de células que expressam dc-sign
US8895028B2 (en) * 2012-07-20 2014-11-25 Arbovax, Inc. Methods and compositions for dengue virus 3 (DV3) infectious clone
US9701719B2 (en) 2012-09-27 2017-07-11 Research Development Foundation Attenuated Chikungunya virus
AR107262A1 (es) 2016-01-27 2018-04-11 Lilly Co Eli Inactivación de patógenos por delipidación
CN109943592B (zh) * 2019-04-29 2020-11-17 华中农业大学 含猪伪狂犬病病毒gD蛋白基因的重组杆状病毒转移载体、重组杆状病毒及制备方法和应用

Also Published As

Publication number Publication date
CN1553961A (zh) 2004-12-08
NZ503128A (en) 2001-08-31
CA2302809A1 (en) 1999-03-25
DE69836499T2 (de) 2007-10-11
KR20010024148A (ko) 2001-03-26
AU737088B2 (en) 2001-08-09
EP1037603A1 (de) 2000-09-27
AU9399698A (en) 1999-04-05
CN1284859C (zh) 2006-11-15
DE69836499D1 (de) 2007-01-04
CA2302809C (en) 2011-08-09
RU2218403C2 (ru) 2003-12-10
WO1999013818A3 (en) 2003-12-04
TW589381B (en) 2004-06-01
JP2003525564A (ja) 2003-09-02
EP1037603A4 (de) 2004-03-17
ZA988446B (en) 2000-03-22
EP1037603B1 (de) 2006-11-22
JP4318399B2 (ja) 2009-08-19
ATE345813T1 (de) 2006-12-15
IL134978A (en) 2008-03-20
WO1999013818A2 (en) 1999-03-25
US6306401B1 (en) 2001-10-23
HK1033544A1 (en) 2001-09-07

Similar Documents

Publication Publication Date Title
IL134978A0 (en) Membrane virus host range mutations and their uses as vaccine substrates
Farquhar et al. Functional organization of amphibian skin
Langosch et al. The role of transmembrane domains in membrane fusion
EP1555319A3 (de) Modifizierte Nukleinsaüresequenzen und Verfahren zur Erhöhung der mRNA-niveau und der Proteinexpression in Zellsystemen
WO2003068947A8 (en) Assay electrodes having immobilized lipid/protein layers and methods of making and using the same
WO2009091912A3 (en) Improved mammalian expression vectors and uses thereof
NZ320276A (en) Method and preparations for stabilizing biological materials by drying methods without freezing
WO2005081911A3 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF HIV INFECTION USING TRIM5α
DE59402827D1 (de) Verfahren zur gewinnung nativer, oligomerer, glykosylierter ektodomänen viraler membranproteine, deren verwendung, insbesondere als impfstoff gegen hiv
Hiebert et al. Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5
DE69920747D1 (de) Methode zur herstellung von rekombinanten zellen
JP2007502623A (ja) 膜タンパク質におけるフリンプロテアーゼ開裂部位の挿入およびその使用法
BR9811675A (pt) Genes isolados para proteìna da membrana de célula dentrìtica
Kraus et al. Open reading frame III of Borna disease virus encodes a nonglycosylated matrix protein
Dormeyer et al. A practical guide for the identification of membrane and plasma membrane proteins in human embryonic stem cells and human embryonal carcinoma cells
KR880701283A (ko) Aids의 원인이 되는 비루스의 당단백질을 암호화하는 비루스 벡터, 백신 및 항체
BR9811850A (pt) Expressão recombinante de peptìdeo c de insulina
WO2001042283A3 (en) Sex-chromosome-specific proteins, species specific and sperm specific proteins and methods for their identification and isolation
WO2005006960A3 (en) Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays
Petri Jr et al. Glycoprotein micelles isolated from vesicular stomatitis virus spontaneously partition into sonicated phosphatidylcholine vesicles
Sobel Myosin rings and spreading in mouse blastomeres.
WO1999047673A3 (en) Isolated mammalian membrane protein genes and related reagents
Lu et al. Phosphorylation of protein tyrosine by human erythrocyte casein kinase A
Kimura Further evidence of the similarity of microtubule protein from mitotic apparatus and sperm tail of the sea urchin, as a substrate in thiol-disulfide exchange reaction
Laster et al. Viral and non-viral induced fusion of pronase-digested human erythrocyte ghosts

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed