DE69836499D1 - Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat - Google Patents

Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat

Info

Publication number
DE69836499D1
DE69836499D1 DE69836499T DE69836499T DE69836499D1 DE 69836499 D1 DE69836499 D1 DE 69836499D1 DE 69836499 T DE69836499 T DE 69836499T DE 69836499 T DE69836499 T DE 69836499T DE 69836499 D1 DE69836499 D1 DE 69836499D1
Authority
DE
Germany
Prior art keywords
membrane
membranes
vaccine
viruses
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69836499T
Other languages
English (en)
Other versions
DE69836499T2 (de
Inventor
T Brown
Racquel Hernandez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Development Foundation
Original Assignee
Research Development Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Development Foundation filed Critical Research Development Foundation
Application granted granted Critical
Publication of DE69836499D1 publication Critical patent/DE69836499D1/de
Publication of DE69836499T2 publication Critical patent/DE69836499T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36161—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69836499T 1997-09-18 1998-09-18 Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat Expired - Lifetime DE69836499T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5966897P 1997-09-18 1997-09-18
US59668P 1997-09-18
PCT/US1998/019556 WO1999013818A2 (en) 1997-09-18 1998-09-18 Membrane virus host range mutations and their uses as vaccine substrates

Publications (2)

Publication Number Publication Date
DE69836499D1 true DE69836499D1 (de) 2007-01-04
DE69836499T2 DE69836499T2 (de) 2007-10-11

Family

ID=22024455

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69836499T Expired - Lifetime DE69836499T2 (de) 1997-09-18 1998-09-18 Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat

Country Status (16)

Country Link
US (1) US6306401B1 (de)
EP (1) EP1037603B1 (de)
JP (1) JP4318399B2 (de)
KR (1) KR20010024148A (de)
CN (1) CN1284859C (de)
AT (1) ATE345813T1 (de)
AU (1) AU737088B2 (de)
CA (1) CA2302809C (de)
DE (1) DE69836499T2 (de)
HK (1) HK1033544A1 (de)
IL (2) IL134978A0 (de)
NZ (1) NZ503128A (de)
RU (1) RU2218403C2 (de)
TW (1) TW589381B (de)
WO (1) WO1999013818A2 (de)
ZA (1) ZA988446B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7335363B2 (en) * 1997-09-18 2008-02-26 Research Development Foundation Membrane virus host range mutations and their uses as vaccine substrates
US6589533B1 (en) * 1997-09-18 2003-07-08 Research Development Foundation Genetically-engineered alphaviruses, flaviviruses, and bunyaviruses with modified envelope transmembrane glycoproteins and altered host-range phenotype
US7128915B2 (en) * 1997-09-18 2006-10-31 Research Development Foundation Membrane virus host range mutations and their uses as vaccine substrates
EP1100944A1 (de) * 1998-07-30 2001-05-23 The Johns Hopkins University School Of Medicine Zielgerichteter alphavirus und vektoren der alphavirus
EP2963118B1 (de) * 2005-06-01 2017-08-09 California Institute of Technology Verfahren zur gezielten genabgabe über virale vektoren
CN100427918C (zh) * 2006-06-05 2008-10-22 中国科学院南海海洋研究所 一种海水鱼类卵子电镜扫描样品制备方法
EP2526774A3 (de) 2006-07-21 2013-03-06 California Institute of Technology Zielgesteuerte Genabgabe für die Immunisierung mit Dendritenzellen
SI2770061T1 (sl) 2009-07-24 2019-02-28 Immune Design Corp. Neintegrirani lentiviralni vektorji
WO2011119628A2 (en) 2010-03-23 2011-09-29 The Regents Of The University Of California Compositions and methods for self-adjuvanting vaccines against microbes and tumors
BR112012024224A2 (pt) * 2010-03-24 2016-11-29 Arbovax Inc mutações da faixa de hospedeiro de flavivírus e seu uso.
US8889148B2 (en) 2010-07-01 2014-11-18 Research Development Foundation Flavivirus host-range mutations and uses thereof
US9713635B2 (en) 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
US8323662B1 (en) 2012-03-30 2012-12-04 Immune Design Corp. Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
PT2831095T (pt) 2012-03-30 2019-01-30 Immune Design Corp Partículas de vectores lentivirais com melhor eficácia de transdução de células que expressam dc-sign
US8895028B2 (en) * 2012-07-20 2014-11-25 Arbovax, Inc. Methods and compositions for dengue virus 3 (DV3) infectious clone
US9701719B2 (en) 2012-09-27 2017-07-11 Research Development Foundation Attenuated Chikungunya virus
AR107262A1 (es) 2016-01-27 2018-04-11 Lilly Co Eli Inactivación de patógenos por delipidación
CN109943592B (zh) * 2019-04-29 2020-11-17 华中农业大学 含猪伪狂犬病病毒gD蛋白基因的重组杆状病毒转移载体、重组杆状病毒及制备方法和应用

Also Published As

Publication number Publication date
CN1553961A (zh) 2004-12-08
NZ503128A (en) 2001-08-31
CA2302809A1 (en) 1999-03-25
DE69836499T2 (de) 2007-10-11
KR20010024148A (ko) 2001-03-26
AU737088B2 (en) 2001-08-09
EP1037603A1 (de) 2000-09-27
AU9399698A (en) 1999-04-05
CN1284859C (zh) 2006-11-15
CA2302809C (en) 2011-08-09
RU2218403C2 (ru) 2003-12-10
WO1999013818A3 (en) 2003-12-04
TW589381B (en) 2004-06-01
JP2003525564A (ja) 2003-09-02
EP1037603A4 (de) 2004-03-17
ZA988446B (en) 2000-03-22
EP1037603B1 (de) 2006-11-22
JP4318399B2 (ja) 2009-08-19
ATE345813T1 (de) 2006-12-15
IL134978A0 (en) 2001-05-20
IL134978A (en) 2008-03-20
WO1999013818A2 (en) 1999-03-25
US6306401B1 (en) 2001-10-23
HK1033544A1 (en) 2001-09-07

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