ATE345813T1 - Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat - Google Patents

Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat

Info

Publication number
ATE345813T1
ATE345813T1 AT98947150T AT98947150T ATE345813T1 AT E345813 T1 ATE345813 T1 AT E345813T1 AT 98947150 T AT98947150 T AT 98947150T AT 98947150 T AT98947150 T AT 98947150T AT E345813 T1 ATE345813 T1 AT E345813T1
Authority
AT
Austria
Prior art keywords
membrane
membranes
vaccine
viruses
proteins
Prior art date
Application number
AT98947150T
Other languages
English (en)
Inventor
Dennis T Brown
Racquel Hernandez
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Application granted granted Critical
Publication of ATE345813T1 publication Critical patent/ATE345813T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36161—Methods of inactivation or attenuation
AT98947150T 1997-09-18 1998-09-18 Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat ATE345813T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5966897P 1997-09-18 1997-09-18

Publications (1)

Publication Number Publication Date
ATE345813T1 true ATE345813T1 (de) 2006-12-15

Family

ID=22024455

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98947150T ATE345813T1 (de) 1997-09-18 1998-09-18 Virus mit membranmutationen für ein witsspektrum und deren verwendung als vakzinsubstrat

Country Status (16)

Country Link
US (1) US6306401B1 (de)
EP (1) EP1037603B1 (de)
JP (1) JP4318399B2 (de)
KR (1) KR20010024148A (de)
CN (1) CN1284859C (de)
AT (1) ATE345813T1 (de)
AU (1) AU737088B2 (de)
CA (1) CA2302809C (de)
DE (1) DE69836499T2 (de)
HK (1) HK1033544A1 (de)
IL (2) IL134978A0 (de)
NZ (1) NZ503128A (de)
RU (1) RU2218403C2 (de)
TW (1) TW589381B (de)
WO (1) WO1999013818A2 (de)
ZA (1) ZA988446B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7128915B2 (en) * 1997-09-18 2006-10-31 Research Development Foundation Membrane virus host range mutations and their uses as vaccine substrates
US7335363B2 (en) 1997-09-18 2008-02-26 Research Development Foundation Membrane virus host range mutations and their uses as vaccine substrates
US6589533B1 (en) * 1997-09-18 2003-07-08 Research Development Foundation Genetically-engineered alphaviruses, flaviviruses, and bunyaviruses with modified envelope transmembrane glycoproteins and altered host-range phenotype
JP2002523053A (ja) * 1998-07-30 2002-07-30 ジョーンズ ホプキンス ユニバーシティー スクール オブ メディシン 標的化されたアルファウイルスおよびアルファウイルスベクター
AU2006252406B2 (en) * 2005-06-01 2012-05-17 California Institute Of Technology Method of targeted gene delivery using viral vectors
CN100427918C (zh) * 2006-06-05 2008-10-22 中国科学院南海海洋研究所 一种海水鱼类卵子电镜扫描样品制备方法
PT2520168E (pt) 2006-07-21 2014-04-29 California Inst Of Techn Administração de gene alvo para vacinação de células dendríticas
PL2456786T5 (pl) 2009-07-24 2017-10-31 Immune Design Corp Wektory lentiwirusowe pseudotypowane glikoproteiną otoczki wirusa sindbis
WO2011119628A2 (en) * 2010-03-23 2011-09-29 The Regents Of The University Of California Compositions and methods for self-adjuvanting vaccines against microbes and tumors
US10081795B2 (en) * 2010-03-24 2018-09-25 Research Development Foundation Flavivirus host range mutations and uses thereof
WO2012003320A2 (en) 2010-07-01 2012-01-05 Research Development Foundation Flavivirus host-range mutations and uses thereof
US9713635B2 (en) 2012-03-30 2017-07-25 Immune Design Corp. Materials and methods for producing improved lentiviral vector particles
US8323662B1 (en) 2012-03-30 2012-12-04 Immune Design Corp. Methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein
EA038702B1 (ru) 2012-03-30 2021-10-07 Иммьюн Дизайн Корп. Лентивирусные векторные частицы, имеющие улучшенную эффективность трансдукции клеток, экспрессирующих dc-sign
US8895028B2 (en) * 2012-07-20 2014-11-25 Arbovax, Inc. Methods and compositions for dengue virus 3 (DV3) infectious clone
WO2014052588A1 (en) 2012-09-27 2014-04-03 Research Development Foundation Attenuated chikungunya virus
AR107262A1 (es) 2016-01-27 2018-04-11 Lilly Co Eli Inactivación de patógenos por delipidación
CN109943592B (zh) * 2019-04-29 2020-11-17 华中农业大学 含猪伪狂犬病病毒gD蛋白基因的重组杆状病毒转移载体、重组杆状病毒及制备方法和应用

Also Published As

Publication number Publication date
KR20010024148A (ko) 2001-03-26
EP1037603A4 (de) 2004-03-17
NZ503128A (en) 2001-08-31
IL134978A0 (en) 2001-05-20
AU9399698A (en) 1999-04-05
CA2302809C (en) 2011-08-09
WO1999013818A2 (en) 1999-03-25
IL134978A (en) 2008-03-20
RU2218403C2 (ru) 2003-12-10
CN1553961A (zh) 2004-12-08
CN1284859C (zh) 2006-11-15
JP2003525564A (ja) 2003-09-02
CA2302809A1 (en) 1999-03-25
WO1999013818A3 (en) 2003-12-04
JP4318399B2 (ja) 2009-08-19
TW589381B (en) 2004-06-01
EP1037603B1 (de) 2006-11-22
EP1037603A1 (de) 2000-09-27
US6306401B1 (en) 2001-10-23
ZA988446B (en) 2000-03-22
AU737088B2 (en) 2001-08-09
DE69836499D1 (de) 2007-01-04
DE69836499T2 (de) 2007-10-11
HK1033544A1 (en) 2001-09-07

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