IL132758A0 - Methods for treating inflammation and inflammatory diseases using padprt - Google Patents
Methods for treating inflammation and inflammatory diseases using padprtInfo
- Publication number
- IL132758A0 IL132758A0 IL13275898A IL13275898A IL132758A0 IL 132758 A0 IL132758 A0 IL 132758A0 IL 13275898 A IL13275898 A IL 13275898A IL 13275898 A IL13275898 A IL 13275898A IL 132758 A0 IL132758 A0 IL 132758A0
- Authority
- IL
- Israel
- Prior art keywords
- padprt
- methods
- inflammatory diseases
- treating inflammation
- inflammation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/855,616 US5908861A (en) | 1997-05-13 | 1997-05-13 | Methods for treating inflammation and inflammatory disease using pADPRT inhibitors |
US09/056,396 US6303629B1 (en) | 1997-05-13 | 1998-04-06 | Methods for treating inflammation, inflammatory diseases, arthritis and stroke using pADPRT inhibitors |
PCT/US1998/010033 WO1998051308A1 (fr) | 1997-05-13 | 1998-05-13 | Procede de traitement de l'inflammation ou de maladies inflammatoires a l'aide d'inhibiteurs de poly-adp ribose polymerase |
Publications (1)
Publication Number | Publication Date |
---|---|
IL132758A0 true IL132758A0 (en) | 2001-03-19 |
Family
ID=26735288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13275898A IL132758A0 (en) | 1997-05-13 | 1998-05-13 | Methods for treating inflammation and inflammatory diseases using padprt |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1009404A4 (fr) |
JP (1) | JP4362638B2 (fr) |
CN (1) | CN1198614C (fr) |
AU (2) | AU745790B2 (fr) |
BR (1) | BR9809115A (fr) |
CA (1) | CA2289119C (fr) |
IL (1) | IL132758A0 (fr) |
NZ (1) | NZ501650A (fr) |
WO (2) | WO1998051307A1 (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
OA11749A (en) | 1999-01-11 | 2005-07-19 | Agouron Pharma | Tricyclic inhibitors of poly(adp-ribose)polymerases. |
ECSP003637A (es) | 1999-08-31 | 2002-03-25 | Agouron Pharma | Inhibidores triciclicos de poli (adp-ribosa) polimerasas |
ES2282410T3 (es) | 2001-05-08 | 2007-10-16 | Kudos Pharmaceuticals Limited | Derivados de isoquinolinona como inhibidores de parp. |
DE60335359D1 (de) | 2002-04-30 | 2011-01-27 | Kudos Pharm Ltd | Phthalazinonderivate |
US7449464B2 (en) | 2003-03-12 | 2008-11-11 | Kudos Pharmaceuticals Limited | Phthalazinone derivatives |
GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
TW200536830A (en) | 2004-02-06 | 2005-11-16 | Chugai Pharmaceutical Co Ltd | 1-(2H)-isoquinolone derivative |
TWI389897B (zh) | 2005-02-22 | 2013-03-21 | Chugai Pharmaceutical Co Ltd | 1- (2H) -isoquinolinone derivatives |
RU2008100017A (ru) * | 2005-06-10 | 2009-07-20 | Бипар Сайенсиз, Инк. (Us) | Модуляторы parp и способ лечения рака |
GB0521373D0 (en) | 2005-10-20 | 2005-11-30 | Kudos Pharm Ltd | Pthalazinone derivatives |
CA2662335A1 (fr) * | 2006-09-05 | 2008-03-13 | Valeria Ossovskaya | Procedes de conception d'inhibiteurs de parp et leurs utilisations |
WO2008030891A2 (fr) * | 2006-09-05 | 2008-03-13 | Bipar Sciences, Inc. | Inhibition de la synthèse d'acides gras au moyen d'inhibiteurs parp et méthodes de traitement associées |
CN101641013B (zh) | 2007-01-22 | 2014-07-30 | Gtx公司 | 核受体结合剂 |
US9623021B2 (en) | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
PT2118074E (pt) | 2007-02-01 | 2014-03-20 | Resverlogix Corp | Compostos para a prevenção e tratamento de doenças cardiovasculares |
AU2008299721A1 (en) | 2007-09-14 | 2009-03-19 | Astrazeneca Ab | Phthalazinone derivatives |
UY31603A1 (es) | 2008-01-23 | 2009-08-31 | Derivados de ftalazinona | |
EP2346837B8 (fr) | 2008-06-26 | 2015-04-15 | Resverlogix Corporation | Procédés de préparation de dérivés de quinazolinone |
HUE030800T2 (en) | 2008-10-07 | 2017-05-29 | Astrazeneca Uk Ltd | Pharmaceutical Form No. 514 |
EP2377871A4 (fr) | 2008-11-28 | 2012-07-25 | Chugai Pharmaceutical Co Ltd | Dérivé de 1-(2h)-isoquinolone |
EP2382194B1 (fr) | 2009-01-08 | 2014-03-12 | Resverlogix Corp. | Composés pour la prévention et le traitement de maladies cardiovasculaires |
NZ708314A (en) | 2009-03-18 | 2017-08-25 | Resverlogix Corp | Quinazolinones for use as anticancer agents |
BRPI1014956B8 (pt) | 2009-04-22 | 2021-05-25 | Resverlogix Corp | agentes anti-inflamatórios |
PL2773354T3 (pl) | 2011-11-01 | 2019-12-31 | Resverlogix Corp. | Doustna formulacja o natychmiastowym uwalnianiu dla podstawowych chinazolinów |
WO2014080290A2 (fr) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Amines cycliques servant d'inhibiteurs de bromodomaines |
US9765039B2 (en) | 2012-11-21 | 2017-09-19 | Zenith Epigenetics Ltd. | Biaryl derivatives as bromodomain inhibitors |
JP2016507496A (ja) | 2012-12-21 | 2016-03-10 | ゼニス・エピジェネティクス・コーポレイションZenith Epigenetics Corp. | ブロモドメイン阻害剤としての新規複素環式化合物 |
JO3789B1 (ar) | 2015-03-13 | 2021-01-31 | Resverlogix Corp | التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة |
US11433074B2 (en) | 2017-06-22 | 2022-09-06 | Triact Therapeutics, Inc. | Methods of treating glioblastoma |
US11628144B2 (en) | 2017-09-29 | 2023-04-18 | Triact Therapeutics, Inc. | Iniparib formulations and uses thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6518890A (en) | 1989-09-26 | 1991-04-28 | Regents Of The University Of California, The | 6-amino-1,2-benzopyrones useful for treatment of viral diseases |
US5484951A (en) | 1990-10-19 | 1996-01-16 | Octamer, Incorporated | 5-iodo-6-amino-6-nitroso-1,2-benzopyrones useful as cytostatic and antiviral agents |
US5464871A (en) | 1993-05-12 | 1995-11-07 | Octamer, Inc. | Aromatic nitro and nitroso compounds and their metabolites useful as anti-viral and anti-tumor agents |
US5516941A (en) | 1991-10-22 | 1996-05-14 | Octamer, Inc. | Specific inactivators of "retroviral" (asymmetric) zinc fingers |
US5482975A (en) | 1991-10-22 | 1996-01-09 | Octamer, Inc. | Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents |
US5473074A (en) | 1991-10-22 | 1995-12-05 | Octamer, Incorporated | Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents and anti-tumor agents-54 |
DE4436127A1 (de) | 1994-09-27 | 1996-03-28 | Deutsches Rheumaforschungszent | Verwendung von aromatischen Amiden und Säuren zur Behandlung von rheumatischen Erkrankungen |
AU5259296A (en) * | 1995-04-07 | 1996-10-23 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of athero sclerosis |
US10766598B2 (en) | 2017-06-14 | 2020-09-08 | The Boeing Company | Wing-to-fuselage joints and aircraft including the same |
-
1998
- 1998-05-13 NZ NZ501650A patent/NZ501650A/en not_active IP Right Cessation
- 1998-05-13 WO PCT/US1998/009768 patent/WO1998051307A1/fr active Application Filing
- 1998-05-13 IL IL13275898A patent/IL132758A0/xx unknown
- 1998-05-13 CN CNB988063891A patent/CN1198614C/zh not_active Expired - Fee Related
- 1998-05-13 WO PCT/US1998/010033 patent/WO1998051308A1/fr not_active Application Discontinuation
- 1998-05-13 JP JP54960898A patent/JP4362638B2/ja not_active Expired - Fee Related
- 1998-05-13 EP EP98922359A patent/EP1009404A4/fr not_active Ceased
- 1998-05-13 AU AU74926/98A patent/AU745790B2/en not_active Ceased
- 1998-05-13 AU AU74847/98A patent/AU7484798A/en not_active Abandoned
- 1998-05-13 BR BR9809115-8A patent/BR9809115A/pt not_active Application Discontinuation
- 1998-05-13 CA CA2289119A patent/CA2289119C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4362638B2 (ja) | 2009-11-11 |
JP2002502367A (ja) | 2002-01-22 |
EP1009404A4 (fr) | 2009-07-01 |
AU7484798A (en) | 1998-12-08 |
WO1998051308A1 (fr) | 1998-11-19 |
NZ501650A (en) | 2001-11-30 |
EP1009404A1 (fr) | 2000-06-21 |
AU745790B2 (en) | 2002-03-28 |
CN1261278A (zh) | 2000-07-26 |
CN1198614C (zh) | 2005-04-27 |
CA2289119C (fr) | 2011-03-15 |
AU7492698A (en) | 1998-12-08 |
CA2289119A1 (fr) | 1998-11-19 |
BR9809115A (pt) | 2002-01-02 |
WO1998051307A1 (fr) | 1998-11-19 |
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