IL132153A0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number: IL132153A0
Authority: IL; Israel
Prior art keywords: pct; date; novel compounds; sec; pub
Prior art date: 1997-04-15

Application number

IL13215398A

Other languages

English (en)

Original Assignee

Astra Pharma Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-15

Filing date

1998-04-07

Publication date

2001-03-19

1998-04-07 Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod

2001-03-19 Publication of IL132153A0 publication Critical patent/IL132153A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

IL13215398A 1997-04-15 1998-04-07 Novel compounds IL132153A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9701398A SE9701398D0 (sv)	1997-04-15	1997-04-15	Novel compounds
PCT/SE1998/000640 WO1998046606A1 (en)	1997-04-15	1998-04-07	Novel compounds

Publications (1)

Publication Number	Publication Date
IL132153A0 true IL132153A0 (en)	2001-03-19

Family

ID=20406576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13215398A IL132153A0 (en)	1997-04-15	1998-04-07	Novel compounds

Country Status (21)

Country	Link
US (1)	US6028074A (et)
EP (1)	EP0975636B1 (et)
JP (1)	JP2001520645A (et)
KR (1)	KR20010006350A (et)
CN (1)	CN1259951A (et)
AT (1)	ATE245648T1 (et)
AU (1)	AU733066B2 (et)
BR (1)	BR9808540A (et)
CA (1)	CA2286078A1 (et)
DE (1)	DE69816608T2 (et)
EE (1)	EE9900465A (et)
HU (1)	HUP0002104A3 (et)
ID (1)	ID22746A (et)
IL (1)	IL132153A0 (et)
IS (1)	IS5198A (et)
NO (1)	NO995006L (et)
PL (1)	PL336230A1 (et)
SE (1)	SE9701398D0 (et)
SK (1)	SK135699A3 (et)
TR (1)	TR199902538T2 (et)
WO (1)	WO1998046606A1 (et)

Families Citing this family (50)

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SE9801399D0 (sv)	1998-04-21	1998-04-21	Astra Pharma Prod	Method and apparatus for filling containers
GC0000177A (en) *	1998-12-17	2006-03-29	Smithkline Beecham	Thrombopoietin mimetics
CY2010012I2 (el)	2000-05-25	2020-05-29	Novartis Ag	Μιμητικα θρομβοποιητινης
US6875786B2 (en)	2001-03-01	2005-04-05	Smithkline Beecham Corporation	Thrombopoietin mimetics
IL160307A0 (en)	2001-08-31	2004-07-25	Univ Rockefeller	Phosphodiesterase activity and regulation of phosphodiesterase 1-b-mediated signaling in brain
AR040083A1 (es)	2002-05-22	2005-03-16	Smithkline Beecham Corp	Compuesto bis-(monoetanolamina) del acido 3'-[(2z)-[1-(3,4-dimetilfenil) -1,5-dihidro-3-metil-5-oxo-4h-pirazol-4-iliden] hidrazino] -2'-hidroxi-[1,1'-bifenil]-3-carboxilico, procedimiento para prepararlo, composicion farmaceutica que lo comprende, procedimiento para preparar dicha composicion farmac
TW200526638A (en)	2003-10-22	2005-08-16	Smithkline Beecham Corp	2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline
WO2006127918A2 (en) *	2005-05-24	2006-11-30	Ott David M	Personal care and medicinal products incorporating bound organosulfur groups
ES2645371T3 (es)	2005-06-06	2017-12-05	Intra-Cellular Therapies, Inc.	Compuestos orgánicos
US9255099B2 (en)	2006-06-06	2016-02-09	Intra-Cellular Therapies, Inc.	Pyrazolo[3,4-D]pyrimidine-4,6(5H,7H)-diones as phosphodiesterase 1 inhibitors
EP2081431B1 (en)	2006-11-13	2013-01-16	Intra-Cellular Therapies, Inc.	Organic compounds
WO2008070095A1 (en)	2006-12-05	2008-06-12	Intra-Cellular Therapies, Inc.	Novel uses
ECSP077628A (es)	2007-05-03	2008-12-30	Smithkline Beechman Corp	Nueva composición farmacéutica
KR20100094551A (ko) *	2007-12-06	2010-08-26	인트라-셀룰라 써래피스, 인코퍼레이티드.	유기 화합물
CN101970444A (zh)	2007-12-06	2011-02-09	细胞内治疗公司	有机化合物
BRPI0922809A2 (pt)	2008-12-06	2018-05-29	Intracellular Therapies Inc	compostos orgânicos
EP2367431B1 (en)	2008-12-06	2015-08-05	Intra-Cellular Therapies, Inc.	Organic compounds
MX2011005933A (es)	2008-12-06	2011-12-16	Intra Cellular Therapies Inc	Compuestos organicos.
SG171776A1 (en)	2008-12-06	2011-07-28	Intra Cellular Therapies Inc	Organic compounds
US8664207B2 (en)	2008-12-06	2014-03-04	Intra-Cellular Therapies, Inc.	Organic compounds
SG171777A1 (en)	2008-12-06	2011-07-28	Intra Cellular Therapies Inc	Organic compounds
US11464781B2 (en)	2009-02-25	2022-10-11	Intra-Cellular Therapies, Inc.	PDE1 inhibitors for ophthalmic disorders
SG174403A1 (en)	2009-03-23	2011-10-28	Glenmark Pharmaceuticals Sa	Isothiazolo-pyrimidinedione derivatives as trpa1 modulators
UA108069C2 (uk) *	2009-03-23	2015-03-25	Гленмарк Фармасьютікалс, С.А.	Злиті піримідиндіонові похідні як модулятори trpa1
US8623880B2 (en)	2009-03-23	2014-01-07	Glenmark Pharmaceuticals S.A.	Fused pyrimidine-dione derivatives as TRPA1 modulators
AU2010227225A1 (en)	2009-03-23	2011-09-15	Glenmark Pharmaceuticals, S.A.	Furopyrimidinedione derivatives as TRPA1 modulators
US9468637B2 (en)	2009-05-13	2016-10-18	Intra-Cellular Therapies, Inc.	Organic compounds
EP3127427B1 (en)	2009-05-29	2020-01-08	Novartis Ag	Methods of administration of thrombopoietin agonist compounds
SG10201507362TA (en)	2009-08-05	2015-10-29	Intra Cellular Therapies Inc	Novel Regulatory Proteins And Inhibitors
TW201206937A (en)	2010-05-31	2012-02-16	Intra Cellular Therapies Inc	Organic compounds
EP2576551A4 (en)	2010-05-31	2014-04-16	Intra Cellular Therapies Inc	ORGANIC COMPOUNDS
US9371327B2 (en)	2010-05-31	2016-06-21	Intra-Cellular Therapies, Inc.	PDE1 inhibitor compounds
US9434730B2 (en)	2010-05-31	2016-09-06	Intra-Cellular Therapies, Inc.	PDE1 inhibitor compounds
US10561656B2 (en)	2011-06-10	2020-02-18	Intra-Cellular Therapies, Inc.	Organic compounds
MY165622A (en)	2012-06-08	2018-04-18	Glenmark Pharmaceuticals Sa	Amides of 2-amino-4aryl thiazole compounds and their salts
US9801882B2 (en)	2013-02-17	2017-10-31	Intra-Cellular Therapies, Inc.	Phosphodiesterase-1 inhibitors and their use in treatment of cardiovascular diseases
JP2016518343A (ja)	2013-03-15	2016-06-23	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	新規使用
JP6437519B2 (ja)	2013-03-15	2018-12-12	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	有機化合物
WO2015106032A1 (en)	2014-01-08	2015-07-16	Intra-Cellular Therapies, Inc.	Products and pharmaceutical compositions
JP6810613B2 (ja)	2014-06-20	2021-01-06	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	有機化合物
US10285992B2 (en)	2014-08-07	2019-05-14	Intra-Cellular Therapies, Inc.	Combinations of PDE1 inhibitors and NEP inhibitors and associated methods
US9546175B2 (en)	2014-08-07	2017-01-17	Intra-Cellular Therapies, Inc.	Organic compounds
TWI686394B (zh)	2014-08-07	2020-03-01	美商內胞醫療公司	有機化合物
EP3725789B1 (en)	2014-09-17	2022-03-09	Intra-Cellular Therapies, Inc.	7,8-dihydro-[2h]-imidazo-[1,2-a]pyrazolo[4,3-e]pyrimidin-4(5h)-one derivatives as phosphodiesterase 1 (pde1) inhibitors for treating diseases, disorders or injuries of the central nervous system (cns)
CN107205993B (zh)	2014-12-06	2021-03-09	细胞内治疗公司	有机化合物
AU2015357496B2 (en)	2014-12-06	2019-09-19	Intra-Cellular Therapies, Inc.	Organic compounds
WO2017172795A1 (en)	2016-03-28	2017-10-05	Intra-Cellular Therapies, Inc.	Novel compositions and methods
CN109311886B (zh) *	2016-06-23	2021-11-09	豪夫迈·罗氏有限公司	[1,2,3]***并[4,5-d]嘧啶衍生物
EP3509589B1 (en)	2016-09-12	2021-11-17	Intra-Cellular Therapies, Inc.	Novel uses
US11839614B2 (en)	2018-01-31	2023-12-12	Intra-Cellular Therapies, Inc.	Methods for treating or mitigating cardiotoxicity characterized by inhibition of adenosine A2 signaling and/or adenosine A2 receptor expression

Family Cites Families (5)

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Publication number	Priority date	Publication date	Assignee	Title
EP0063381A1 (de) *	1981-04-22	1982-10-27	Byk Gulden Lomberg Chemische Fabrik GmbH	Neue Pyrazolo(3,4-d)pyrimidine, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel
US4603203A (en) *	1983-12-14	1986-07-29	Takeda Chemical Industries, Ltd.	3-aminopyrazolo[3,4-d]pyrimidine derivatives and production thereof
EP0237289A3 (en) *	1986-03-14	1988-07-27	Takeda Chemical Industries, Ltd.	Pyrazolo [3,4-d] pyrimidine derivatives, their production and use
TW444018B (en) *	1992-12-17	2001-07-01	Pfizer	Pyrazolopyrimidines
DE69323212T2 (de) *	1992-12-17	1999-05-27	Pfizer	Pyrazole mit crf antagonistischer aktivität

1997
- 1997-04-15 SE SE9701398A patent/SE9701398D0/xx unknown
1998
- 1998-04-07 TR TR1999/02538T patent/TR199902538T2/xx unknown
- 1998-04-07 KR KR1019997009435A patent/KR20010006350A/ko not_active Application Discontinuation
- 1998-04-07 AT AT98917859T patent/ATE245648T1/de not_active IP Right Cessation
- 1998-04-07 SK SK1356-99A patent/SK135699A3/sk unknown
- 1998-04-07 PL PL98336230A patent/PL336230A1/xx unknown
- 1998-04-07 EP EP98917859A patent/EP0975636B1/en not_active Expired - Lifetime
- 1998-04-07 ID IDW991207A patent/ID22746A/id unknown
- 1998-04-07 DE DE69816608T patent/DE69816608T2/de not_active Expired - Fee Related
- 1998-04-07 AU AU70909/98A patent/AU733066B2/en not_active Ceased
- 1998-04-07 HU HU0002104A patent/HUP0002104A3/hu unknown
- 1998-04-07 BR BR9808540-9A patent/BR9808540A/pt not_active IP Right Cessation
- 1998-04-07 CA CA002286078A patent/CA2286078A1/en not_active Abandoned
- 1998-04-07 WO PCT/SE1998/000640 patent/WO1998046606A1/en active IP Right Grant
- 1998-04-07 JP JP54380398A patent/JP2001520645A/ja not_active Ceased
- 1998-04-07 IL IL13215398A patent/IL132153A0/xx unknown
- 1998-04-07 CN CN98806075A patent/CN1259951A/zh active Pending
- 1998-04-07 EE EEP199900465A patent/EE9900465A/et unknown
- 1998-08-07 US US09/068,304 patent/US6028074A/en not_active Expired - Fee Related
1999
- 1999-09-27 IS IS5198A patent/IS5198A/is unknown
- 1999-10-14 NO NO995006A patent/NO995006L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO995006D0 (no)	1999-10-14
EP0975636A1 (en)	2000-02-02
PL336230A1 (en)	2000-06-19
TR199902538T2 (xx)	2000-02-21
HUP0002104A3 (en)	2002-03-28
JP2001520645A (ja)	2001-10-30
EP0975636B1 (en)	2003-07-23
DE69816608T2 (de)	2004-04-15
IS5198A (is)	1999-09-27
US6028074A (en)	2000-02-22
DE69816608D1 (de)	2003-08-28
CN1259951A (zh)	2000-07-12
AU7090998A (en)	1998-11-11
BR9808540A (pt)	2000-05-23
KR20010006350A (ko)	2001-01-26
SK135699A3 (en)	2000-05-16
CA2286078A1 (en)	1998-10-22
EE9900465A (et)	2000-04-17
SE9701398D0 (sv)	1997-04-15
HUP0002104A2 (hu)	2001-01-29
NO995006L (no)	1999-10-14
ATE245648T1 (de)	2003-08-15
WO1998046606A1 (en)	1998-10-22
AU733066B2 (en)	2001-05-03
ID22746A (id)	1999-12-09

Publication	Publication Date	Title
IL132153A0 (en)	2001-03-19	Novel compounds
PL340836A1 (en)	2001-02-26	Novel compounds
IL132763A0 (en)	2001-03-19	Novel compounds
IS5082A (is)	1999-06-14	Pýrróló[3,4-D]pýrimídínon-afleiður og notkun þeirra sem lyfja
UA66801C2 (uk)	2004-06-15	Триазоло[4,5-d]піримідинові сполуки, спосіб їх одержання (варіанти), фармацевтична композиція на їх основі та спосіб лікування порушень агрегації тромбоцитів
HUT75776A (en)	1997-05-28	Pyrazolo and pyrrolopyridines, their using, pharmaceutical compositions containing them and intermediates
PL338518A1 (en)	2000-11-06	Novel compounds
IL108520A (en)	1997-09-30	2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a\| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IL134111A0 (en)	2001-04-30	Triazolo [4,5-d] pyrimidine compounds, their use anovel compounds s medicaments, compositions containing them and processes for their preparation
DE60005940D1 (de)	2003-11-20	Zusammensetzung zur behandlung sexueller funktionsstörungen die phosphodiesterase-5 inhibitoren enthaltend
GR3034354T3 (en)	2000-12-29	IMIDAZO 1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF
DE69911785D1 (de)	2003-11-06	Triazolo[4,5-d]pyrimidin-verbindungen
AU3862997A (en)	1998-02-20	Stable derivatives of ubiquinole, processes for their production and pharmaceutical use thereof
IL88726A0 (en)	1989-07-31	Dihydrothienobenzodiazepinone derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof
HU9503099D0 (en)	1995-12-28	New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components
AU7436098A (en)	1998-11-13	Use of mizolastine for preparing a medicine for treating inflammation