IL117331A - Indole derivatives their preparation and pharmaceutical compositions containing them - Google Patents
Indole derivatives their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL117331A IL117331A IL11733196A IL11733196A IL117331A IL 117331 A IL117331 A IL 117331A IL 11733196 A IL11733196 A IL 11733196A IL 11733196 A IL11733196 A IL 11733196A IL 117331 A IL117331 A IL 117331A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- indole derivatives
- indole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9504361.8A GB9504361D0 (en) | 1995-03-04 | 1995-03-04 | Heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117331A0 IL117331A0 (en) | 1996-07-23 |
| IL117331A true IL117331A (en) | 2000-06-29 |
Family
ID=10770638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11733196A IL117331A (en) | 1995-03-04 | 1996-03-01 | Indole derivatives their preparation and pharmaceutical compositions containing them |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5919811A (hu) |
| EP (1) | EP0813524A1 (hu) |
| JP (1) | JPH11501041A (hu) |
| KR (1) | KR19980702735A (hu) |
| CN (1) | CN1182417A (hu) |
| AR (1) | AR002711A1 (hu) |
| AU (1) | AU708291B2 (hu) |
| BR (1) | BR9607346A (hu) |
| CA (1) | CA2214583A1 (hu) |
| CO (1) | CO4700452A1 (hu) |
| CZ (1) | CZ277997A3 (hu) |
| EA (1) | EA000308B1 (hu) |
| GB (1) | GB9504361D0 (hu) |
| HU (1) | HUP9801838A3 (hu) |
| IL (1) | IL117331A (hu) |
| MX (1) | MX9706605A (hu) |
| NO (1) | NO309323B1 (hu) |
| NZ (1) | NZ303200A (hu) |
| PE (1) | PE62396A1 (hu) |
| PL (1) | PL322084A1 (hu) |
| TW (1) | TW438773B (hu) |
| WO (1) | WO1996027588A1 (hu) |
| ZA (1) | ZA961697B (hu) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5886191A (en) * | 1997-08-18 | 1999-03-23 | Dupont Pharmaceuticals Company | Amidinoindoles, amidinoazoles, and analogs thereof |
| GB9902455D0 (en) * | 1999-02-05 | 1999-03-24 | Zeneca Ltd | Chemical compounds |
| AU2002364549B2 (en) * | 2001-12-10 | 2007-11-22 | Amgen, Inc | Vanilloid receptor ligands and their use in treatments |
| GB0205176D0 (en) * | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| MXPA05007513A (es) * | 2003-01-14 | 2005-09-21 | Cytokinetics Inc | Compuestos, composiciones y metodos. |
| BRPI0512193B8 (pt) * | 2004-06-17 | 2021-05-25 | Cytokinetics Inc | composto ou sal farmaceuticamente aceitável, composição farmacêutica, e, uso do composto ou sal |
| US7176222B2 (en) | 2004-07-27 | 2007-02-13 | Cytokinetics, Inc. | Syntheses of ureas |
| US7538223B2 (en) * | 2005-08-04 | 2009-05-26 | Cytokinetics, Inc. | Compounds, compositions and methods |
| TW200808321A (en) | 2005-12-15 | 2008-02-16 | Cytokinetics Inc | Certain chemical entities, compositions and methods |
| EP1959947A2 (en) * | 2005-12-15 | 2008-08-27 | Cytokinetics, Inc. | Certain chemical entities, compositions and methods |
| US20070208000A1 (en) * | 2005-12-15 | 2007-09-06 | Morgan Bradley P | Certain chemical entities, compositions and methods |
| US7825120B2 (en) * | 2005-12-15 | 2010-11-02 | Cytokinetics, Inc. | Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas |
| WO2007078815A2 (en) * | 2005-12-16 | 2007-07-12 | Cytokinetics, Inc. | Certain chemical entities, compositions, and methods |
| EP1962852B1 (en) * | 2005-12-19 | 2017-01-25 | Cytokinetics, Inc. | Compounds, compositions and methods |
| WO2009035927A2 (en) * | 2007-09-13 | 2009-03-19 | Arete Therapeutics, Inc. | Bis-cyclyl substitued ureas or amides as soluble epoxide hydrolase inhibitors |
| PE20091101A1 (es) | 2007-12-18 | 2009-07-26 | Pharminox Ltd | AMIDAS DE ACIDO 3-SUBSTITUIDO-4-OXO-3,4-DIHIDRO-IMIDAZO[5,1-d] [1,2,3,5-TETRACINA-8-CARBOXILICO Y SU EMPLEO |
| BRPI1011822A2 (pt) | 2009-06-23 | 2016-03-29 | Pharminox Ltd | "compostos de 3-substituída-8-substituída-3h-imidazo[5,1-d][1,2,3,5-tetrazin-4-ona e sua aplicação" |
| US20130012706A1 (en) | 2010-03-01 | 2013-01-10 | Pharminox Limited | Methods and Intermediates for the Synthesis of 4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazines |
| WO2012085501A1 (en) | 2010-12-20 | 2012-06-28 | Pharminox Limited | 8 - sulfo - imidazotetrazin- 4 - one compounds and their use as anticancer drug |
| TW202128630A (zh) | 2019-11-11 | 2021-08-01 | 荷蘭商卡普三世責任有限公司 | 工業規模上用於生產ε-己內醯胺及硫酸銨之方法及設備 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5145845A (en) * | 1991-05-14 | 1992-09-08 | Warner-Lambert Co. | Substituted 2-carboxylindoles having pharmaceutical activity |
| GB9208492D0 (en) * | 1992-04-16 | 1992-06-03 | Glaxo Spa | Heterocyclic compounds |
| GB9304500D0 (en) * | 1993-03-05 | 1993-04-21 | Glaxo Spa | Heterocyclic compounds |
| US5519048A (en) * | 1993-05-27 | 1996-05-21 | Merrell Pharmaceuticals Inc. | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof |
-
1995
- 1995-03-04 GB GBGB9504361.8A patent/GB9504361D0/en active Pending
-
1996
- 1996-03-01 BR BR9607346A patent/BR9607346A/pt unknown
- 1996-03-01 CZ CZ972779A patent/CZ277997A3/cs unknown
- 1996-03-01 AU AU49438/96A patent/AU708291B2/en not_active Ceased
- 1996-03-01 CN CN96193467A patent/CN1182417A/zh active Pending
- 1996-03-01 IL IL11733196A patent/IL117331A/xx not_active IP Right Cessation
- 1996-03-01 CA CA002214583A patent/CA2214583A1/en not_active Abandoned
- 1996-03-01 CO CO96009937A patent/CO4700452A1/es unknown
- 1996-03-01 KR KR1019970706142A patent/KR19980702735A/ko not_active Application Discontinuation
- 1996-03-01 WO PCT/EP1996/000840 patent/WO1996027588A1/en not_active Application Discontinuation
- 1996-03-01 PE PE1996000145A patent/PE62396A1/es not_active Application Discontinuation
- 1996-03-01 EP EP96905833A patent/EP0813524A1/en not_active Withdrawn
- 1996-03-01 PL PL96322084A patent/PL322084A1/xx unknown
- 1996-03-01 MX MX9706605A patent/MX9706605A/es unknown
- 1996-03-01 US US08/894,702 patent/US5919811A/en not_active Expired - Fee Related
- 1996-03-01 NZ NZ303200A patent/NZ303200A/xx unknown
- 1996-03-01 AR ARP960101610A patent/AR002711A1/es unknown
- 1996-03-01 ZA ZA9601697A patent/ZA961697B/xx unknown
- 1996-03-01 JP JP8526590A patent/JPH11501041A/ja active Pending
- 1996-03-01 EA EA199700160A patent/EA000308B1/ru not_active IP Right Cessation
- 1996-03-01 HU HU9801838A patent/HUP9801838A3/hu unknown
- 1996-03-19 TW TW085103238A patent/TW438773B/zh active
-
1997
- 1997-09-03 NO NO974043A patent/NO309323B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AR002711A1 (es) | 1998-04-29 |
| PE62396A1 (es) | 1997-01-11 |
| NO974043D0 (no) | 1997-09-03 |
| ZA961697B (en) | 1997-10-01 |
| EP0813524A1 (en) | 1997-12-29 |
| IL117331A0 (en) | 1996-07-23 |
| NO309323B1 (no) | 2001-01-15 |
| US5919811A (en) | 1999-07-06 |
| BR9607346A (pt) | 1997-12-30 |
| AU4943896A (en) | 1996-09-23 |
| EA000308B1 (ru) | 1999-04-29 |
| WO1996027588A1 (en) | 1996-09-12 |
| NO974043L (no) | 1997-11-03 |
| JPH11501041A (ja) | 1999-01-26 |
| CO4700452A1 (es) | 1998-12-29 |
| KR19980702735A (ko) | 1998-08-05 |
| MX9706605A (es) | 1998-02-28 |
| AU708291B2 (en) | 1999-07-29 |
| HUP9801838A3 (en) | 2000-04-28 |
| CN1182417A (zh) | 1998-05-20 |
| HUP9801838A2 (hu) | 1998-12-28 |
| TW438773B (en) | 2001-06-07 |
| CZ277997A3 (cs) | 1998-06-17 |
| GB9504361D0 (en) | 1995-04-26 |
| CA2214583A1 (en) | 1996-09-12 |
| EA199700160A1 (ru) | 1998-02-26 |
| PL322084A1 (en) | 1998-01-05 |
| NZ303200A (en) | 1999-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |