IL109848A - Vitamin d compounds their preparation and pharmaceutical and cosmetic compositions containing them - Google Patents

Vitamin d compounds their preparation and pharmaceutical and cosmetic compositions containing them

Info

Publication number
IL109848A
IL109848A IL10984894A IL10984894A IL109848A IL 109848 A IL109848 A IL 109848A IL 10984894 A IL10984894 A IL 10984894A IL 10984894 A IL10984894 A IL 10984894A IL 109848 A IL109848 A IL 109848A
Authority
IL
Israel
Prior art keywords
group
compounds
vitamin
pharmaceutical
preparation
Prior art date
Application number
IL10984894A
Other languages
English (en)
Other versions
IL109848A0 (en
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22098649&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL109848(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of IL109848A0 publication Critical patent/IL109848A0/xx
Publication of IL109848A publication Critical patent/IL109848A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/32—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.3.0) system, e.g. indenols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/457—Saturated compounds containing a keto group being part of a ring containing halogen
    • C07C49/467—Saturated compounds containing a keto group being part of a ring containing halogen polycyclic
    • C07C49/473—Saturated compounds containing a keto group being part of a ring containing halogen polycyclic a keto group being part of a condensed ring system
    • C07C49/477—Saturated compounds containing a keto group being part of a ring containing halogen polycyclic a keto group being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
IL10984894A 1993-06-04 1994-06-01 Vitamin d compounds their preparation and pharmaceutical and cosmetic compositions containing them IL109848A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/070,998 US5449668A (en) 1993-06-04 1993-06-04 Vitamin D compounds and method of preparing these compounds

Publications (2)

Publication Number Publication Date
IL109848A0 IL109848A0 (en) 1994-10-07
IL109848A true IL109848A (en) 1999-06-20

Family

ID=22098649

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10984894A IL109848A (en) 1993-06-04 1994-06-01 Vitamin d compounds their preparation and pharmaceutical and cosmetic compositions containing them

Country Status (15)

Country Link
US (3) US5449668A (xx)
EP (1) EP0633245B1 (xx)
KR (1) KR100301876B1 (xx)
CN (1) CN1050829C (xx)
AT (1) ATE142198T1 (xx)
AU (1) AU679221B2 (xx)
DE (1) DE69400469T2 (xx)
DK (1) DK0633245T3 (xx)
ES (1) ES2094023T3 (xx)
GR (1) GR3021581T3 (xx)
HU (1) HU219593B (xx)
IL (1) IL109848A (xx)
NZ (1) NZ260647A (xx)
PL (1) PL179104B1 (xx)
ZA (1) ZA943830B (xx)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5486509A (en) * 1991-06-28 1996-01-23 University Of Miami Method of preventing and treating chemotherapy-induced alopecia
ATE143007T1 (de) * 1991-07-05 1996-10-15 Duphar Int Res Vitamin-d derivat, verfahren zu dessen herstellung sowie zwischenprodukte dafür
US6291444B1 (en) * 1993-06-16 2001-09-18 Wisconsin Alumni Research Foundation Treatment of t-cell immunodeficiencies with vitamin D compounds
GB9314400D0 (en) * 1993-07-12 1993-08-25 Leo Pharm Prod Ltd Produktionsaktieselskab) chemical compounds
US5552392A (en) * 1993-11-03 1996-09-03 Wisconsin Alumni Research Foundation Method of treating hypoparathyroidism with (20S) vitamin D compounds
US5502050A (en) * 1993-11-29 1996-03-26 Cornell Research Foundation, Inc. Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis
CA2206876A1 (en) * 1994-11-21 1996-05-30 Wisconsin Alumni Research Foundation 18,19-dinor-vitamin d compounds
US5661140A (en) * 1994-11-21 1997-08-26 Wisconsin Alumni Research Foundation 18-nor-vitamin D compounds
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
IL118156A (en) * 1995-05-09 2001-08-26 Duphar Int Res Vitamin d compounds, their preparation and pharmaceutical compositions containing them
JP3738450B2 (ja) * 1995-11-20 2006-01-25 喜代司 喜多 ビタミンｄ類やビタミンｋ類を配合した外用剤
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
GB9622590D0 (en) * 1996-10-30 1997-01-08 Leo Pharm Prod Ltd Chemical compounds
US6187331B1 (en) 1997-06-10 2001-02-13 New Vision Co., Ltd. Composition for prophylaxis and/or treatment of dry syndrome comprising vitamin D
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
US6359152B2 (en) 1997-07-21 2002-03-19 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
AU2413499A (en) 1997-12-17 1999-07-05 Schering Aktiengesellschaft Vitamin d derivatives with phosphorous atoms in the side chains
EP0927721A1 (de) * 1997-12-17 1999-07-07 Schering Aktiengesellschaft Neue Vitamin D-Derivate mit Phosphoratomen in den Seitenketten, Zwischenprodukte bei ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
WO2000002580A2 (en) * 1998-07-10 2000-01-20 Duke University Medical Center Therapies using hemoproteins
WO2000053578A1 (fr) * 1999-03-11 2000-09-14 Kuraray Co., Ltd. Derives de la vitamine d et leur procede de preparation
US6912420B2 (en) * 2001-04-10 2005-06-28 Cardiac Pacemakers, Inc. Cardiac rhythm management system for hypotension
US7191000B2 (en) * 2001-07-31 2007-03-13 Cardiac Pacemakers, Inc. Cardiac rhythm management system for edema
JP2005504279A (ja) * 2001-09-27 2005-02-10 ザ・コカ−コーラ・カンパニー 食品のビタミン強化
US7563810B2 (en) 2002-11-06 2009-07-21 Celgene Corporation Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
US8034831B2 (en) * 2002-11-06 2011-10-11 Celgene Corporation Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
US20060171983A1 (en) * 2003-07-30 2006-08-03 Jin Tian Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease
WO2005027930A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. 2-alkylene-19-nor-vitamin d derivatives for the treatment of osteosarcoma
SI1730108T1 (sl) * 2004-03-18 2008-08-31 Leo Pharma As Stereoselektivna sinteza analogov vitamina D
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US7387610B2 (en) * 2004-08-19 2008-06-17 Cardiac Pacemakers, Inc. Thoracic impedance detection with blood resistivity compensation
WO2006094064A2 (en) * 2005-02-28 2006-09-08 Avocet Polymer Technologies, Inc. Method of reducing scars with vitamin d
US7603170B2 (en) * 2005-04-26 2009-10-13 Cardiac Pacemakers, Inc. Calibration of impedance monitoring of respiratory volumes using thoracic D.C. impedance
US7907997B2 (en) 2005-05-11 2011-03-15 Cardiac Pacemakers, Inc. Enhancements to the detection of pulmonary edema when using transthoracic impedance
US7340296B2 (en) 2005-05-18 2008-03-04 Cardiac Pacemakers, Inc. Detection of pleural effusion using transthoracic impedance
EA201691980A1 (ru) 2009-01-27 2017-07-31 БЕРГ ЭлЭлСи Способы уменьшения побочных эффектов, связанных с химиотерапией
SG178382A1 (en) 2009-08-14 2012-04-27 Berg Biosystems Llc Vitamin d3 and analogs thereof for treating alopecia
ES2396524B2 (es) * 2012-12-11 2013-08-01 Universidade De Santiago De Compostela Intermedios versátiles y funcionalizados en la síntesis de vitamina D y nuevos derivados de vitamina D
WO2014194133A1 (en) 2013-05-29 2014-12-04 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN105481256B (zh) * 2015-12-30 2018-02-16 三川德青科技有限公司 一种铅锌浮选尾矿微晶玻璃及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3666587D1 (en) * 1985-08-02 1989-11-30 Leo Pharm Prod Ltd Novel vitamin d analogues
DE68907483T2 (de) * 1988-04-21 1993-10-21 Leo Pharm Prod Ltd Vitamin d analoge.
US5401732A (en) * 1989-02-23 1995-03-28 Leo Pharmaceutical Products Ltd. A/S Kemiske Fabrik Produkionsaktiese Skab Vitamin D analogues
US5378695A (en) * 1989-02-23 1995-01-03 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Vitamin D analogues
GB8904154D0 (en) * 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds
US5321018A (en) * 1989-03-09 1994-06-14 Wisconsin Alumni Research Foundation Use of 1α-hydroxylated-19-nor-vitamin D compounds to treat psoriasis
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
NZ232734A (en) * 1989-03-09 1991-11-26 Wisconsin Alumni Res Found 19-nor vitamin d derivatives and pharmaceutical compositions
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
DE4011682A1 (de) * 1990-04-06 1991-10-10 Schering Ag 24-oxa-derivate in der vitamin d-reihe
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
US5486509A (en) * 1991-06-28 1996-01-23 University Of Miami Method of preventing and treating chemotherapy-induced alopecia
ATE143007T1 (de) * 1991-07-05 1996-10-15 Duphar Int Res Vitamin-d derivat, verfahren zu dessen herstellung sowie zwischenprodukte dafür
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds

Also Published As

Publication number Publication date
DE69400469D1 (de) 1996-10-10
CN1050829C (zh) 2000-03-29
HU219593B (hu) 2001-05-28
GR3021581T3 (en) 1997-02-28
AU6347294A (en) 1994-12-08
ATE142198T1 (de) 1996-09-15
PL303652A1 (en) 1994-12-12
PL179104B1 (pl) 2000-07-31
HUT67928A (en) 1995-05-29
DE69400469T2 (de) 1997-03-27
US5449668A (en) 1995-09-12
KR100301876B1 (ko) 2001-11-22
NZ260647A (en) 1995-11-27
ZA943830B (en) 1995-05-04
EP0633245A1 (en) 1995-01-11
KR950000662A (ko) 1995-01-03
USRE36854E (en) 2000-09-05
EP0633245B1 (en) 1996-09-04
ES2094023T3 (es) 1997-01-01
DK0633245T3 (da) 1996-12-23
HU9401637D0 (en) 1994-08-29
IL109848A0 (en) 1994-10-07
AU679221B2 (en) 1997-06-26
US6075015A (en) 2000-06-13
CN1099385A (zh) 1995-03-01

Similar Documents

Publication Publication Date Title
IL109848A (en) Vitamin d compounds their preparation and pharmaceutical and cosmetic compositions containing them
HUP9601001A2 (hu) Benzimidazolil-, benzoxazolil- és benzotiazolil-oxazolidinon-származékok, eljárás azok előállítására és ezeket tartalmazó gyógyszerkészítmények
HUT62886A (en) Process for producing new, furyl and thienyl group-substituted taxane derivatives and pharmaceutical compositions comprising such compounds as active ingredient
HUT62873A (en) Process for producing alkoxy-substituted taxane derivatives and pharmaceutical compositions comprising same as active ingredient
EP0420722A3 (en) Lipid compounds, derivatives of sphingosines, process for their preparation and their use, especially in cosmetics and in dermopharmaceutics
IL118156A (en) Vitamin d compounds, their preparation and pharmaceutical compositions containing them
IL116326A0 (en) Vitamin D compounds their preparation and pharmaceutical compositions containing them
IL164967A0 (en) Use of estrogen antagonists and estrogen agonists in the preparation of medicament for inhibiting pathological conditions
GB1536515A (en) Compositions containing silicon derivatives
NO800447L (no) Derivater av difenylhydantoin, farmasoeytiske preparater inneholdende slike preparater, samt fremgangsmaate til fremstilling av de aktive forbindelser
MX9203597A (es) Nuevos derivados de la pristinamicina iib y composiciones farmaceuticas que los contienen.
ATE19773T1 (de) Nitroaliphatische verbindungen, verfahren zu deren herstellung und deren verwendung.
MX9201279A (es) Derivados de 1-fenil-3-aza bi ciclo alquil-imidazolidin-2-onas, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
MX9306394A (es) Derivados de benzofurano, proceso para su preparacion y composicion farmaceutica que los contiene
SE8600046L (sv) Anvendning av en esterforening som temporer baktericid och produkt innehallande esterforeningen
IL112362A0 (en) Vitamin D compounds, their preparation and pharmaceutical compositions containing them
ES2009924A6 (es) Procedimiento para preparar nuevos tetrahidrofuranos y tetrahidrotiofenos.
AU4953997A (en) New histidine derivatives, preparation process, and their use as free antiradical agents
ES475004A1 (es) Un procedimiento para la preparacion de sales de eteres del acido clavulanico
CA2097997A1 (en) Vitamin d compounds and method of preparing these compounds
HUP9801716A1 (hu) 5H,10H-Imidazo[1,2-a]indeno[1,2-e]pirazin-4-on-származékok, eljárás előállításukra,az ezeket tartalmazó gyógyszerkészítmények és a vegyületek intermedierjei

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees