IL106810A0 - Phosphono substituted tetrazole derivatives - Google Patents
Phosphono substituted tetrazole derivativesInfo
- Publication number
- IL106810A0 IL106810A0 IL106810A IL10681093A IL106810A0 IL 106810 A0 IL106810 A0 IL 106810A0 IL 106810 A IL106810 A IL 106810A IL 10681093 A IL10681093 A IL 10681093A IL 106810 A0 IL106810 A0 IL 106810A0
- Authority
- IL
- Israel
- Prior art keywords
- lower alkyl
- carboxyl
- formula
- aryl
- substituted
- Prior art date
Links
- 150000003536 tetrazoles Chemical class 0.000 title abstract 2
- 125000001476 phosphono group Chemical group [H]OP(*)(=O)O[H] 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 5
- -1 6-tetrahydronaphthyl Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 101100295738 Gallus gallus COR3 gene Proteins 0.000 abstract 1
- 102000003729 Neprilysin Human genes 0.000 abstract 1
- 108090000028 Neprilysin Proteins 0.000 abstract 1
- 125000005042 acyloxymethyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/14—Use of materials for tobacco smoke filters of organic materials as additive
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/16—Use of materials for tobacco smoke filters of inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F1/00—General methods for the manufacture of artificial filaments or the like
- D01F1/02—Addition of substances to the spinning solution or to the melt
- D01F1/10—Other agents for modifying properties
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F2/00—Monocomponent artificial filaments or the like of cellulose or cellulose derivatives; Manufacture thereof
- D01F2/24—Monocomponent artificial filaments or the like of cellulose or cellulose derivatives; Manufacture thereof from cellulose derivatives
- D01F2/28—Monocomponent artificial filaments or the like of cellulose or cellulose derivatives; Manufacture thereof from cellulose derivatives from organic cellulose esters or ethers, e.g. cellulose acetate
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Textile Engineering (AREA)
- Materials Engineering (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Manufacturing & Machinery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Artificial Filaments (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/940,118 US5273990A (en) | 1992-09-03 | 1992-09-03 | Phosphono substituted tetrazole derivatives |
US07/959,000 US5250522A (en) | 1992-10-09 | 1992-10-09 | Phosphono/biaryl substituted amino acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IL106810A0 true IL106810A0 (en) | 1993-12-08 |
Family
ID=27130130
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL106810A IL106810A0 (en) | 1992-09-03 | 1993-08-26 | Phosphono substituted tetrazole derivatives |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0660840B1 (no) |
JP (1) | JP3130938B2 (no) |
KR (1) | KR950702996A (no) |
AT (1) | ATE152727T1 (no) |
AU (1) | AU5089693A (no) |
CA (1) | CA2142348A1 (no) |
DE (1) | DE69310524T2 (no) |
DK (1) | DK0660840T3 (no) |
ES (1) | ES2101342T3 (no) |
FI (1) | FI950925A0 (no) |
GR (1) | GR3024314T3 (no) |
HU (1) | HUT72615A (no) |
IL (1) | IL106810A0 (no) |
NO (1) | NO950827L (no) |
NZ (1) | NZ255878A (no) |
WO (1) | WO1994005677A1 (no) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5583123A (en) * | 1994-12-22 | 1996-12-10 | Ciba-Geigy Corporation | Certain tetrazole derivatives |
US5550119A (en) * | 1995-03-02 | 1996-08-27 | Ciba-Geigy Corporation | Phosphono substituted tetrazole derivatives as ECE inhibitors |
US8673974B2 (en) * | 2010-11-16 | 2014-03-18 | Novartis Ag | Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD141930A1 (de) * | 1979-02-20 | 1980-05-28 | Kurt Issleib | Verfahren zur herstellung von n-phosphonomethylaminosaeuren und deren ester |
US5155100A (en) * | 1991-05-01 | 1992-10-13 | Ciba-Geigy Corporation | Phosphono/biaryl substituted dipeptide derivatives |
-
1992
- 1992-10-16 JP JP05507272A patent/JP3130938B2/ja not_active Expired - Lifetime
-
1993
- 1993-08-24 WO PCT/US1993/007965 patent/WO1994005677A1/en active IP Right Grant
- 1993-08-24 NZ NZ255878A patent/NZ255878A/en unknown
- 1993-08-24 HU HU9500648A patent/HUT72615A/hu unknown
- 1993-08-24 AT AT93920310T patent/ATE152727T1/de not_active IP Right Cessation
- 1993-08-24 KR KR1019950700824A patent/KR950702996A/ko not_active Application Discontinuation
- 1993-08-24 ES ES93920310T patent/ES2101342T3/es not_active Expired - Lifetime
- 1993-08-24 DE DE69310524T patent/DE69310524T2/de not_active Expired - Fee Related
- 1993-08-24 DK DK93920310.5T patent/DK0660840T3/da active
- 1993-08-24 EP EP93920310A patent/EP0660840B1/en not_active Expired - Lifetime
- 1993-08-24 CA CA002142348A patent/CA2142348A1/en not_active Abandoned
- 1993-08-24 AU AU50896/93A patent/AU5089693A/en not_active Abandoned
- 1993-08-26 IL IL106810A patent/IL106810A0/xx unknown
-
1995
- 1995-03-01 FI FI950925A patent/FI950925A0/fi not_active Application Discontinuation
- 1995-03-02 NO NO950827A patent/NO950827L/no unknown
-
1997
- 1997-07-30 GR GR970401963T patent/GR3024314T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0660840B1 (en) | 1997-05-07 |
AU5089693A (en) | 1994-03-29 |
EP0660840A1 (en) | 1995-07-05 |
NO950827L (no) | 1995-06-09 |
HUT72615A (en) | 1996-05-28 |
GR3024314T3 (en) | 1997-10-31 |
NO950827D0 (no) | 1995-03-02 |
DE69310524D1 (de) | 1997-06-12 |
ATE152727T1 (de) | 1997-05-15 |
CA2142348A1 (en) | 1994-03-17 |
DK0660840T3 (da) | 1997-07-14 |
JPH08501098A (ja) | 1996-02-06 |
KR950702996A (ko) | 1995-08-23 |
HU9500648D0 (en) | 1995-04-28 |
JP3130938B2 (ja) | 2001-01-31 |
FI950925A (fi) | 1995-03-01 |
FI950925A0 (fi) | 1995-03-01 |
NZ255878A (en) | 1996-12-20 |
ES2101342T3 (es) | 1997-07-01 |
WO1994005677A1 (en) | 1994-03-17 |
DE69310524T2 (de) | 1997-12-04 |
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