ATE327748T1 - Alkandiol derivate zur behandlung von knochenkrankheiten - Google Patents

Alkandiol derivate zur behandlung von knochenkrankheiten

Info

Publication number
ATE327748T1
ATE327748T1 AT02777456T AT02777456T ATE327748T1 AT E327748 T1 ATE327748 T1 AT E327748T1 AT 02777456 T AT02777456 T AT 02777456T AT 02777456 T AT02777456 T AT 02777456T AT E327748 T1 ATE327748 T1 AT E327748T1
Authority
AT
Austria
Prior art keywords
inhibit
esters
activity
compounds
independently
Prior art date
Application number
AT02777456T
Other languages
English (en)
Inventor
Stuart Ralston
Iain Robert Greig
T Hof Robert Jurgen Van
Kenneth John Armour
Original Assignee
Univ Aberdeen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Aberdeen filed Critical Univ Aberdeen
Application granted granted Critical
Publication of ATE327748T1 publication Critical patent/ATE327748T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT02777456T 2001-10-31 2002-10-31 Alkandiol derivate zur behandlung von knochenkrankheiten ATE327748T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0126157.7A GB0126157D0 (en) 2001-10-31 2001-10-31 Therapeutic compounds

Publications (1)

Publication Number Publication Date
ATE327748T1 true ATE327748T1 (de) 2006-06-15

Family

ID=9924891

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02777456T ATE327748T1 (de) 2001-10-31 2002-10-31 Alkandiol derivate zur behandlung von knochenkrankheiten

Country Status (9)

Country Link
US (1) US7745424B2 (de)
EP (1) EP1441716B1 (de)
JP (1) JP2005511556A (de)
KR (1) KR20050042044A (de)
AT (1) ATE327748T1 (de)
CA (1) CA2465399A1 (de)
DE (1) DE60211935T2 (de)
GB (1) GB0126157D0 (de)
WO (1) WO2003037321A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
US20060286064A1 (en) * 2000-08-30 2006-12-21 Medivas, Llc Therapeutic polymers and methods
ES2298753T3 (es) 2003-05-07 2008-05-16 The University Court Of The University Of Aberdeen Cetonas y cetonas reducidas como agentes terapeuticos para el tratamiento de enfermedades oseas.
US20060188469A1 (en) * 2003-10-14 2006-08-24 Medivas, Llc Vaccine delivery compositions and methods of use
US7589228B2 (en) 2004-05-28 2009-09-15 Nippon Shokubai Co., Ltd. Fluorine-containing compound
GB0412553D0 (en) 2004-06-04 2004-07-07 Univ Aberdeen Therapeutic agents for the treatment of bone conditions
US20070053984A1 (en) * 2005-03-03 2007-03-08 Monique Spann-Wade Topical gels compositions
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
EP1933881B1 (de) 2005-09-22 2019-03-13 Medivas, LLC Feste polymer-abgabezusammensetzungen und anwendungsverfahren dafür
US20080317684A1 (en) * 2006-09-06 2008-12-25 Isw Group, Inc. Topical Compositions
GB0705400D0 (en) 2007-03-21 2007-05-02 Univ Aberdeen Therapeutic compounds andm their use
GB0817207D0 (en) 2008-09-19 2008-10-29 Pimco 2664 Ltd therapeutic apsac compounds and their use
GB0817208D0 (en) 2008-09-19 2008-10-29 Pimco 2664 Ltd Therapeutic apsap compounds and their use
WO2010036973A1 (en) * 2008-09-25 2010-04-01 Comgenrx, Inc. Treatment of hyperproliferative disorders using cardiac glycosides
EP2723800B1 (de) 2011-06-23 2015-10-07 DSM IP Assets B.V. Mikro- oder nanopartikel mit einem biologisch abbaubaren polyesteramid-copolymer zur verwendung bei der verabreichung von bioaktiven substanzen
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
JP2014523911A (ja) * 2011-07-21 2014-09-18 黒▲龍▼江宝▲慶▼隆生物技▲術▼有限責任公司 イブプロフェン系化合物、その調製方法、使用および製剤
US11964956B2 (en) 2012-09-06 2024-04-23 Northeastern University Cannabinergic compounds and uses thereof
US20160108016A1 (en) 2012-09-06 2016-04-21 Northeastern University Novel Cannabinergic Compounds and Uses Thereof
US9580400B2 (en) 2013-02-26 2017-02-28 Northeastern University Cannabinergic nitrate esters and related analogs
EP2818531B1 (de) * 2013-06-25 2017-07-26 Merck Patent GmbH Polymerisierbare Verbindungen und ihre Verwendung für Flüssigkristallanzeigen
GB201311361D0 (en) 2013-06-26 2013-08-14 Pimco 2664 Ltd Compounds and their therapeutic use
EP3262028B1 (de) 2014-12-17 2021-10-27 Pimco 2664 Limited N-(4-hydroxy-4-methyl-cyclohexyl)-4-phenyl-benzenesulfonamide und n-(4-hydroxy-4-methyl-cyclohexyl)-4-(2-pyridyl)-benzenesulfonamide und deren therapeutische verwendung
US10434071B2 (en) 2014-12-18 2019-10-08 Dsm Ip Assets, B.V. Drug delivery system for delivery of acid sensitivity drugs
CN113402386B (zh) * 2021-05-28 2024-05-03 武汉亿科德精细化工有限公司 一种新戊二醇二苯甲酸酯的合成方法
WO2024083934A1 (en) 2022-10-19 2024-04-25 Basf Se Method for preparing 1,4-butanediol diesters

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB663072A (en) 1947-05-24 1951-12-19 British Celanese Improvements relating to compositions comprising organic thermoplastic substances
GB661185A (en) 1947-11-24 1951-11-21 Sterling Drug Inc Improvements in or relating to the production of alkoxyalkyl esters of iodobenzoic acids
GB716877A (en) 1951-07-25 1954-10-13 British Celanese Improvements in polyesters and their intermediates
GB774180A (en) 1953-11-18 1957-05-08 Cecil Reginald Burch Grading or separation of solid materials in liquid suspension
GB774635A (en) 1954-06-29 1957-05-15 Thomae Gmbh Dr K New benzoic acid derivatives, and processes for their preparation
JPS4326316Y1 (de) 1964-11-21 1968-11-01
CH496647A (de) 1967-12-15 1970-09-30 Hoechst Ag Verfahren zur Herstellung von Terephthalsäure-(B-hydroxy-äthyl)-estern
US3689535A (en) 1968-09-26 1972-09-05 John Kollar Process for preparing ethylene glycol esters
US3715389A (en) 1971-03-01 1973-02-06 Halcon International Inc Process for preparing glycol esters from olefinically unsaturated compounds
DE2602030C2 (de) * 1976-01-21 1983-12-01 Henkel KGaA, 4000 Düsseldorf Diphosphonoalkancarbonsäuren und Verfahren zu deren Herstellung
JP2748005B2 (ja) 1988-10-13 1998-05-06 旭電化工業株式会社 光学活性ビフェニル化合物および該化合物含有液晶組成物
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
US5374707A (en) * 1993-02-18 1994-12-20 Monsanto Company Hydroxy ethyl bibenzoate
JP3538444B2 (ja) * 1993-09-30 2004-06-14 株式会社三光開発科学研究所 ジヒドロキシ化合物およびその製造方法
US6124474A (en) 1999-12-21 2000-09-26 Abbott Laboratories Synthesis of chiral 2-azetidinemethanol compounds
JP4326316B2 (ja) 2003-12-09 2009-09-02 日産自動車株式会社 車両のトラクションコントロール装置

Also Published As

Publication number Publication date
EP1441716B1 (de) 2006-05-31
KR20050042044A (ko) 2005-05-04
CA2465399A1 (en) 2003-05-08
GB0126157D0 (en) 2002-01-02
US20040254151A1 (en) 2004-12-16
WO2003037321A1 (en) 2003-05-08
JP2005511556A (ja) 2005-04-28
DE60211935T2 (de) 2007-01-11
EP1441716A1 (de) 2004-08-04
US7745424B2 (en) 2010-06-29
DE60211935D1 (de) 2006-07-06

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